People suffering from sickle cell disease (scd) usually start showing symptoms very early. They can appear to show up even during the first year of life. Symptoms of a sickle cell vary from one person to another and can be mild to serious depending on the condition.

 

Sickle cell disease is a health condition that worsens with time. Despite the absence of any full-proof solution, some treatments prevent further complications. These treatments can help patients receive aid for a lifetime. Simply said, sickle cell diseases can be managed medically.

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Treatment

Treatment in a sickle cell patient depends on the severity of the symptoms. Preventing complications and relieving pain is the primary aim of the diagnosis. They can range from medications to blood transfusions.

 

Concerns

Some of the concerns that need to be taken care of during the treatment of scd are-

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	Prevent painful scenarios
	


A painful episode or sickle cell crisis can be avoided by consuming sufficient fluids, wearing warm clothing, and staying away from sudden temperature changes.

 


	
	Avoid infections
	


Children with sickle cell anemia are made safe from infections by using penicillin. Adults with anemia might need to take penicillin all their lives. Doctors should ensure that all vaccinations in children and adults are periodically done to avoid any infections. However, during the covid-19 pandemic sickle cell patients should take extra care.

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Medications

While there can be numerous ways to manage sickle cell treatment, medications help in a significant way. Some of the prescribed medicines are-


	
	Hydroxyurea- it reduces the frequency of sickle crises. Pregnant women should stay away from this according to experts.
	
	
	Crizanlizumab- this drug injected into the patient can help reduce the sickle crises in adults and children over the age of 16.
	
	
	Voxelotor- it is an oral drug used in children over 12. It lowers the risk of anemia by improving blood flow.
	
	
	Pain-relievers- narcotics to prevent excessive pain can also be used during the treatment.
	


 

Surgical procedures


	
	Blood transfusion
	


It is used to prevent stroke and other related complications in patients. This can increase the number of red blood cells in the body that can help reduce the symptoms.

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	Stem cell transplant
	


It is also called a bone marrow transplant and is used to replace affected bone marrow with a healthy one. This procedure is carried out between matched donor and recipient. Although it is a known cure for sickle cell disease, various risks involved make it a less used practice.

 

Can Sickle Cell Be Cured?

People with sickle cell disease often experience myriad symptoms of the disease that can be controlled by the right nutrition. Reports suggest that nutrition is an increasingly significant factor to prevent symptoms such as slow growth, lower body mass, joint issues, infections, pain crises, and anemia.

There is a greater than the typical requirement for both calories and micronutrients.

The nutritional requirement of a sickle cell patient emphasizes more on vegetables, fruits, whole grains, and more similar food items. These can prevent any deficiencies in the body and also decrease any chances of disease exacerbation.

 


	
	High-calorie nutrient-dense diet
	


The usual energy intake in a sickle cell patient is normally lower than the average values. It is a case even when the condition is asymptomatic where the requirement drops to half the level. As a result, people with sickle cell diseases (especially kids) are at higher risk for impaired growth and considerably lesser fat and fat-free mass, with obesity also posing a risk. It is suggested to have adequate energy supplements in the diet to reach the minimum sufficient requirement of the body that can be done only by proper nutritional assessment.


	
	Adequate fluids
	


Avoiding dehydration is another significant factor to avoid any severe symptoms of sickle cell disease. Sickling of the erythrocytes aggravates in patients who perform hardcore physical work in the heat without drinking enough fluids. This leads to dehydration and can even result in constipation.


	
	Micronutrients
	


Micronutrient deficiencies can be found in sickle cell patients up to a great extent. Several vitamins and minerals like vitamin a, b6, c, e, carotenoids, zinc, and magnesium are often found in fewer numbers in scd patients. A significant drop in blood-antioxidant status may result in acute chest syndrome. The supplementation of these vitamins and minerals can reduce the number of sickled cells in the body. Plant phenols and flavonoids may also help in lowering oxidative stress.


	
	Calcium-rich food
	


Getting plenty of calcium-rich food like dairy products, leafy vegetables, cereals, and fruit juices aids the child's growth and development. This may lead to a stronger physical structure and a greater resistance to the disease.


	
	Omega-3 fatty acid
	


There are reduced proportions of omega-3 polyunsaturated fatty acids in sickle cell patients. These acids aid the fluidity of red blood cell membranes. As a result, they prevent sickle cell crises. Supplemental docosahexaenoic (dha) and eicosapentaenoic (epa) have shown numerous therapeutic benefits in scd patients.


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Role Of Nutrition In Sickle Cell Disease

International yoga day or international day of yoga is celebrated on 21 june annually. It took a shape in the united nations general assembly in 2014 when indian prime minister narendra modi proposed a day for yoga. The mental, physical, and spiritually enticing practice of yoga started being celebrated in 2015.

 

Yoga and its importance

The term'yoga' is derived from sanskrit which means to reunite or join. It is symbolic of the union of mind and body. Yoga originated some 5000 years ago in india. It was developed as a process to interconnect the mind, soul, and body. As it started gaining popularity in the west, it became an exercise and a method to relax. Through yoga, you can easily calm down your nerves, alleviate any physical concerns, get relieved of any chronic pain, and attain bodily well-being.

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Significance of 21 june

June 21 is also called the summer solstice. It is considered the longest day of the year when the sun is out for most parts of the day. From yoga's perspective, the summer solstice allows the transition to dakshinayana. Hence, it was chosen as an ideal day to celebrate a healthy mind and body.

 

Un declaration

After the draft resolution was presented in the un general assembly, it received support from 177 member countries. Pm modi in his statement emphasized yoga's invaluable importance. He also stressed the fact that how yoga connects us to nature.

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Benefits of yoga


	
	Yoga and fitness
	


Yoga ensures that a person is healthy in its true sense. The different postures of yoga encourage overall fitness and balance of the body. In addition, an enhanced mental strength, physical power, stamina, and detoxification of the body.


	
	Yoga and stress relief
	


Some precious moments of yoga each day is a good way to eliminate everyday stress. Be it physical or mental, certain practices like meditation and pranayama are perfect for preventing stress.


	
	Yoga and inner peace
	


There is a serious need for peace in this robust world. Yoga done regularly gives you extensive inner peace. It is vital to calm your disturbed peace. Moreover, breathing exercises in yoga are very helpful against unwanted stress. Immune system enhancement and protection from frequent diseases is another one of yoga s benefits.



 

International Yoga Day: All You Need To Know!

Yoga is a very important part of everyone s life. Yoga is a time tested and natural way to eliminate various diseases and problems with the body as well as the mind. It is antiquated craftsmanship that strengthens the body as well as relaxes the brain with the right dose of mindfulness as well. Yoga tends to stimulate the nervous system and the endocrine, digestive and circulatory systems and improve the functioning of the same.

 

Below mentioned postures affect at least one of these systems, thereby clearing the path for a strong immune system. ;

Shishuasana (child posture): shishuasana is a phenomenal stance that de-congests the abdomen and constructs a superior and stronger immune system.

Setu bandhasana (bridge posture): setu bandhasana opens the heart and enhances the blood flow. It increases the energy in the body to build a strong resistance against pathogens.

Halasana (plow posture): halasana is a pose that requires a backward bend. It discharges white cells in the body and strengthens the immune system.

Bhujangasana (cobra posture): bhujangasana is a mid-section opening posture which discharges white cells that enhance the body s resistance.

Dhanurasana (bow posture): dhanurasana is yet another posture that enhances the flow of white cells by putting weight on the working of the digestive system.

Matsyasana (fish posture): matsyasana stretches the abdomen and chest and strengthens the thymus. This enhances the body's invulnerability level.

Vinyasa adho mukha svanasana (flowing downward facing dog pose): begin with the plank pose, palms lying on the floor just underneath your shoulder and extend the legs backward. The whole body should form a straight line like a board. Taking a full breath, lift your hips off the floor. Hold yourself on the hands and heels. Your head needs to point towards the ground. Take full breaths, two or three times, as you hold the position. Breathe out a deep breath, relax and return to the plank posture. Gradually bring down your body. Slide your hands backward, allowing your palms to rest alongside the chest. Toes need to be in contact with the mat or the floor.

Ayurveda, yoga and meditation are the perfect variables to carry on with a sound life.

 

Yoga Asanas That Can Boost Your Immune System

While yoga is mainly considered to be a physical process that unites our spiritual conscience, there's more to it. Meditation, prayer, breathwork, and rituals are some self-disciplinary practices that make up the entirety of yoga.

 

Benefits

Apart from physical well-being, yoga also ensures that your overall health gets a boost and you feel rejuvenated. Some scientific benefits of yoga are-

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	Increases flexibility
	


Yoga offers many asanas and styles to choose from and almost all of them contribute to improving flexibility. Yoga acts as a catalyst to increase mobility in older people.


	
	Relieves stress
	


Studies suggest that the second most cited reason for people to practice yoga is that it releases stress. Science proves that yoga helps lower the stress and tension levels in individuals.


	
	Boosts mental health
	


Some studies have observed that yoga is an excellent practice to treat major depressive disorder (mdd). Both movement-based and breathing-based yoga therapies are helpful to improve mental health.


	
	Reduces inflammation
	


Reports suggest that yoga reduces inflammation in the body. As a result, it prevents any chronic disease.


	
	Increases strength
	


Some styles and asanas of yoga can also be strength building. Yoga s effectiveness at improving physical strength has been suggested by many reports.


	
	Reduces anxiety
	


There are numerous anxiety disorders that need care such as anxiety disorders, social anxiety, and phobias. Yoga in the form of meditation helps in reducing the symptoms of the same.


	
	Boosts immunity
	


Excessive stress affects your immune system directly. One is more susceptible to diseases if the immunity is weak. As yoga is a proven way to relieve stress and reduce inflammation, it helps the body develop stronger immunity with time.


	
	Improves balance
	


Balance is important for performing daily movements. Yoga has shown considerable progress in improving bodily balance. Being consistent with yoga makes sure that you get long-lasting benefits as well.


	
	Cardiovascular functioning
	


Pranayama or yogic breathing greatly helps numerous systems in the body. Controlled breathing lowers the chances of change in heart rate, stroke, and more.


	
	Improves quality of sleep
	


Yoga improves the quality of sleep. It is also because of the aftereffects of the exercise. However, yoga has some qualities like mental calming and stress relief that allow a sound sleep.


	
	Boosts bone health
	


Isometric contractions in yoga provide a holistic engagement of bones. They also reverse the bone loss related to osteoporosis and osteopenia.


	
	Improves brain functioning
	


Yoga stimulates the functioning of the brain and boosts energy levels. Studies suggest that it can improve executive functioning, mental flexibility, task switching capabilities, and memory.







 

Scientific Benefits Of Yoga

What are the different types of sickle cell disease?

Sickle cell disease or sickle cell disorder is a term often used to talk about a group of diseases affecting hemoglobin. It is the oxygen-carrying element of blood that makes up 2 alpha globins and 2 beta globins. Sickle cell disease happens due to beta-globin mutation and depending on the abnormality in mutation.

Types-
Sickle cell diseases can be of many types depending on the gene mutation in the blood. Some of the common types are-

Sickle hemoglobin s disease (ss)
Hemoglobin ss disease or sickle cell anemia is the most popular type of scd. It takes place when hemoglobin s gene mutation is inherited from both mother and father. In simple words, it happens when the child inherits one substitution beta-globin gene from each parent. In this type, the body only produces hemoglobin s. It is mostly found in people of african and indian origin.

Sickle hemoglobin- c disease (sc):
Patients with sickle hemoglobin sc disease have a moderately dissimilar swapping in their genes of beta-globin. Here, both hemoglobin c and hemoglobin s are inherited from each parent. It may cause similar symptoms like anemia but remains relatively l. People of west african and mediterranean origin are more prone to this.

Hbs beta-thalassemia
People with this type of scd inherit one sickle cell gene s and one gene for beta-thalassemia from each parent. Zero and plus are the two common types of beta-thalassemia. While beta 0 thalassemia usually takes a severe form, beta + thalassemia is a milder form of the disease.

Sickle beta-zero thalassemia
Beta-zero thalassemia takes form when the child inherits the beta s gene from one parent and beta 0 thalassemia gene mutation from the other. With similar symptoms to anemia, it is a slightly severe form of beta-thalassemia.

Sickle beta-plus thalassemia
Substitutions in both beta-globin genes take place in patients with sickle beta thalassemia (sb) disease. This may even lead to the requirement of blood transfusion if no normal beta globin is produced. Mediterranean and caribbean people are more likely to have this disorder.

Hemoglobin sd, hemoglobin se, and hemoglobin so
These are the few rare and not less common types of sickle cell diseases. They are also less severe. People with these forms of scd inherit one sickle cell gene s and one gene from uncommon hemoglobin (d, e, or o) from each parent.

Sickle cell trait
Hbas
People with sct have one sickle cell gene s and one normal gene a from both mother and father. Ones with this disorder show few to no signs of the disease and usually spend a normal life. However, the risk to their future generations still exists.
 

What Are The Different Types Of Sickle Cell Disease?

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