The world celebrates world blood donor day on the 14th of june to raise awareness of the need for safe blood and blood products and to thank voluntary and unpaid blood donors for their life-saving gift of blood. 

Importance of blood donation

The importance of donating blood is not only to save the lives of thousands of people who are deprived of life but also to save the lives of many more who are affected by the various diseases. ;

 

It has also been seen that when people; e have donated their blood, they have gained many health benefits as it helps in weight loss, helps maintain healthy liver and iron levels, it helps reduce the risk of heart attack and cancer. ;

 

A blood donation can save a life of- ;


	
	Victims of natural disasters, including earthquakes
	
	
	Patients with hemophilia, sickle cell disease, or cancer
	
	
	People who suffer traumatic injuries from being in a car accident
	
	
	Surgery patients
	
	
	Shooting or stabbing victims
	
	
	Women who suffer complications during childbirth
	


 

Blood types that are needed most

It s good to donate if you re healthy. However, there s always a need for specific blood and plasma which are universal and can be used when a patient blood type is unknown. For newborn infants or if a patient's particular blood type is unavailable.

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	Type o negative blood is always needed because it can be used in patients regardless of their blood type.
	
	
	Type ab positive plasma can also be transfused to patients with other blood types. 
	


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Donations are constantly needed

Because of their short shelf life of 5 days after being collected, platelet donations are constantly by the blood blank. Red blood cells also have a short shelf life and needed to be used within 42 days after the collection. Cryoprecipitate and plasma can be frozen and stored for up to a year after donation.


 

Some misconceptions about blood donations


	
	The donor will not experience any kind of pain while donating. ;
	
	
	There will be no scarcity of blood in the body after donating the blood as even after the donation the body will have a surplus quantity of blood. 
	
	
	The common misconception everyone has is that they will faint after donating their blood. ;
	
	
	You will be able to resume your everyday activity immediately after donating the blood. 
	
	
	You will not get infected with aids if you donate your blood. ;
	


 

Donating blood is a great way to give back to your community and potentially save a life by only giving up an hour of your time.

World Blood Donor Day: How Can We Save Life By Donating Blood?

What are the different types of sickle cell disease?

Sickle cell disease or sickle cell disorder is a term often used to talk about a group of diseases affecting hemoglobin. It is the oxygen-carrying element of blood that makes up 2 alpha globins and 2 beta globins. Sickle cell disease happens due to beta-globin mutation and depending on the abnormality in mutation.

Types-
Sickle cell diseases can be of many types depending on the gene mutation in the blood. Some of the common types are-

Sickle hemoglobin s disease (ss)
Hemoglobin ss disease or sickle cell anemia is the most popular type of scd. It takes place when hemoglobin s gene mutation is inherited from both mother and father. In simple words, it happens when the child inherits one substitution beta-globin gene from each parent. In this type, the body only produces hemoglobin s. It is mostly found in people of african and indian origin.

Sickle hemoglobin- c disease (sc):
Patients with sickle hemoglobin sc disease have a moderately dissimilar swapping in their genes of beta-globin. Here, both hemoglobin c and hemoglobin s are inherited from each parent. It may cause similar symptoms like anemia but remains relatively l. People of west african and mediterranean origin are more prone to this.

Hbs beta-thalassemia
People with this type of scd inherit one sickle cell gene s and one gene for beta-thalassemia from each parent. Zero and plus are the two common types of beta-thalassemia. While beta 0 thalassemia usually takes a severe form, beta + thalassemia is a milder form of the disease.

Sickle beta-zero thalassemia
Beta-zero thalassemia takes form when the child inherits the beta s gene from one parent and beta 0 thalassemia gene mutation from the other. With similar symptoms to anemia, it is a slightly severe form of beta-thalassemia.

Sickle beta-plus thalassemia
Substitutions in both beta-globin genes take place in patients with sickle beta thalassemia (sb) disease. This may even lead to the requirement of blood transfusion if no normal beta globin is produced. Mediterranean and caribbean people are more likely to have this disorder.

Hemoglobin sd, hemoglobin se, and hemoglobin so
These are the few rare and not less common types of sickle cell diseases. They are also less severe. People with these forms of scd inherit one sickle cell gene s and one gene from uncommon hemoglobin (d, e, or o) from each parent.

Sickle cell trait
Hbas
People with sct have one sickle cell gene s and one normal gene a from both mother and father. Ones with this disorder show few to no signs of the disease and usually spend a normal life. However, the risk to their future generations still exists.
 

What Are The Different Types Of Sickle Cell Disease?

Kidney - prolonged periods of stress can indirectly hurt your kidneys. So you need to be stress free to keep your kidneys healthy.

Stress And Kidney Failure: Are They Connected?

Potassium is one of the seven essential macrominerals found in a variety of foods, including legumes, fish, and leafy vegetables. The mineral plays a vital role in various body functions, such as regulating water balance, heart functioning, and muscle contractions.

Potassium deficiency can lead to weakness, ;fatigue, and constipation. It is therefore important that you include potassium-rich foods in your daily ;diet.

However, keep in mind that taking in more than the required amount of potassium can do more harm than good to your body.

How much should you take in and why?

As per the world health organization, the recommended daily intake of potassium for adults is between 3500mg and 4700mg, as it is safe to consume. When taken in recommended measures, a potassium-rich diet can have some impressive benefits on your overall health. It may reduce or prevent a host of health problems.


	
	Lower high blood pressure
	
	
	Helps eliminate salt insensitivity
	
	
	Reduces your chances of getting a ;stroke by 7%
	
	
	Helps prevent osteoporosis and minimizes the risk of bone fractures
	
	
	Alleviates the risk of ;kidney stones
	


Natural foods are the best source of this mineral. However, you may also turn to supplements, as per your healthcare provider s recommendation.

How much is too much?

Despite its health benefits, potassium should be consumed within the prescribed limit. Going overboard can cause excess potassium to be stored in your blood, and your kidneys may not be able to filter the excess amount   this condition could possibly lead to hyperkalemia. If your potassium levels are between 5.1mmol/l and 6.0mmol/l, you might be at risk of hyperkalemia. Higher than 6.0mmol/l level is considered dangerous   you will need to monitor and manage the condition in order to avoid the risk.

Potassium is essential for bodily functions. A healthy diet and overall eating patterns are important for maintaining good health and keeping illnesses at bay. Be sure to meet your recommended daily intake and avoid exceeding 4700mg of potassium daily. If you are looking to include supplements, talk to your doctor and make sure you stick to the prescribed dosage.

How Safe Is Potassium For Your Health?

Abstract

Background: it is essential to have an understanding of life expectancy and risk factors among patients with sickle cell disease (sickle cell anemia, hemoglobin diseases, and thalassemias). These are required to counsel the patients, target treatment, and plan the right clinical trials.

 

Methods: a research followed 3764 people ranging from birth to 66 years of age and suffering from scd. The procedure was done to understand the life expectancy and calculate the average age at death. Moreover, the study understood the reasons for the death in all 209 adults. It used the proportional-hazards regression analysis to know the risks for an untimely death in adults with sickle cell anemia.

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Results: when the results for young kids and adults with sickle cell anemia were observed, it was found that the average age at death was 48 for women and 42 for men. Moreover, suffering from hemoglobin c disease had an average mortality age of 60 for men and 68 years for women.

 

In people with sickle cell disease, 18% of deaths took place in patients with mainly renal organ failures. 33% of the tested patients were medically free of organ failures but episodes of pain crisis took their life. Out of these patients, 78% experienced chronic pain, chest syndrome, or both, while 22% suffered a stroke that took their lives.

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Clinical modeling showed that people with sickle cell anemia faced acute chest syndrome, seizures, kidney failure, a white-cell count of over 15, 000 per cubic mm, and a low hemoglobin level were related to a risk of early death.

 

Conclusions: results suggested that 50% of patients with sickle cell anemia lived beyond the age of 50. A huge share of those who lost their lives suffered no noticeable chronic organ failure. However, most of them died due to acute episodes of pain or stroke. Early death was seen highest among patients who had symptomatic disease. High levels of fetal hemoglobin suggested improved chances of survival and are assumably a credible source to foresee the risks and other factors related to adult life expectancy.


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Life Expectancy And Risk Factors Involved In Sickle Cell Disease

Diabetes is a common chronic condition that results from excessively high blood glucose. In this condition, either the pancreas fail to produce enough insulin, or your body does not utilize insulin produced by pancreas properly. This might lead to cardiovascular problems and neural problems, as well as health problems like ;depression and ;anxiety. Recent studies reveal that diabetes may have an impact on your reproductive health too.

Effects on men

A common problem that affects men s sexual life is erectile dysfunction. Diabetic men face this as they have low testosterone levels and are unable to maintain an erection during sex. For an erection, constant blood flow is necessary inside the penis. However, as diabetes disrupts the blood flow and damages the blood vessels, men are not able to achieve an erection.

Furthermore, diabetes also damages the arteries and nerves, which again, disturbs the blood flow to the penis. This also causes erectile dysfunction. Other factors that can cause sexual complications among men are- ;


	
	Diabetes-induced obesity
	
	
	High blood pressure
	
	
	Retrograde ejaculation ;  refers to a condition where semen is ejaculated to your bladder, but not through your penis
	


Effects on women

For women, during menopause, blood ;sugar levels may drop due to diabetes. Besides, high blood sugar levels damage the nerves of a woman. This may hinder the ability to feel aroused during sex and lowers sexual stimulation. This reduces their capability to achieve orgasm.

Another common issue among women with diabetes is ;vaginal dryness. This causes a lack of lubrication in the vagina that makes sex painful. Damage to the nerves that lubricate the vagina may be the reason for this. During menopause or after menopause, it can be due to low oestrogen.

Diabetes is more likely to cause vaginal infections such as yeast infections and urinary tract infections. Both of these cause pain during sexual intercourse. If the nerves of the bladder are damaged, it can lead to urinary incontinence ;while sex.

There are certain medications and therapy that may help control diabetes. Additionally, changes in lifestyle such as eating healthy, exercising daily etc. Will enhance your well-being that will significantly improve your blood glucose levels   and in turn, your sex life.

Know How Diabetes Impacts Reproductive Health

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