Irrfan Khan's saddening revelation about his health and diagnosis of Neuroendocrine tumour (NET) has undoubtedly created a rage amongst his fans, which is now being followed by good wishes for speedy recovery from his supporters all across social media.  

The actor shared in an emotional Twitter post that he s been diagnosed with NET, a rare tumour that develops from cells of the neuroendocrine system and grows predominantly in the digestive or respiratory tract - lungs, appendix, small intestine, rectum, and pancreas - it can occur in any part of the body.

Here is more on Irrfan s disease:

What is NET?

A neuroendocrine tumor is characterized by a rapid and abnormal growth that happens in the nerve cells which produce hormones. Hormones control how different organs in the body work.

It is a condition wherein, endocrine cells, the hormone-producing cells of the body, develop a tumor in any part of the body - while it can can grow in lungs or the thymus, or more rarely, in the ovaries, kidneys, or testicles - the most common is lung, intestines, and pancreas.

What causes NET?

A neuroendocrine tumour is quite a rare disease, occurs in less than one per million cases. The exact cause is not known.

The Symptoms-

It can cause a myriad of symptoms, depending on where in the body the NET is.

If it is in your digestive system, it can cause pain or discomfort in the abdomen area that comes and goes. You may feel sick, nauseated, vomited, or there may be a change in how often you pass stools.
If the NET is in the lung, it can cause shortness of breath, chest infections, or you can even have a cough up blood.
Weight loss and loss of appetite may also be some common signs of a neuroendocrine tumour.
Some NETs may overproduce a hormone-like substance called serotonin. This causes a group of symptoms called carcinoid syndrome. Symptoms include wheezing (like asthma), flushing of the skin and diarrhoea.
Who can be affected with NET?

These tumours, depending on the type, are more common in certain age or sex. And few have very strong family history too.
People who have a rare condition called multiple endocrine neoplasia 1 have an increased risk of developing a NET.
Did You Know?

Apple founder  Steve Jobs  died from the same disease in 2011. The tumour affected his pancreas.

Know The Different Types of NET:

Based on the organ that is affected, NET can vary a lot. When the chromaffin cells that produce adrenaline are affected, it is called Pheochromocytoma, and it is related to the stress levels of the body.

When a cell is formed abnormally under the skin and the hair follicles, it is called Merkel cell cancer. This is also called neuroendocrine carcinoma of the skin and the condition can occur anywhere in the body. The commonly occurring places include lungs, gastrointestinal tract, and brain.

The status of the tumour, cancerous (malignant) or noncancerous (benign), decides the survival rate. Often slow-growing and noncancerous, they can invade surrounding parts of the body and at times, turn cancerous and spread across the body. However, you can still choose to live a good quality life with strict modifications in diet and lifestyle. The changes are made after taking into consideration the symptoms of the tumor. The organ where the tumor is formed also matters.

How Is It Treated?

Treatment depends on the location of the tumour, its type, how severe it is and whether it has spread to other parts of the body. Usually, the first treatment choice is surgery to remove the tumour. And, if the NET cannot be removed, your will prescribed with a treatment that will not only relieve the symptoms but will also improve the quality of your life.

How can a NET be prevented?

The first thing you need to do for the prevention of NET is to curb stress. Stress affects the entire body severely.

Lifestyle modifications:

A healthy lifestyle is what you need to stick to if you want to manage its symptoms during the treatment cycle. Your doctor will prescribe you to do exercises at least 4 days a week for a minimum of 30 minutes. You can also try a walk instead of strenuous exercises.

People with carcinoid syndrome may be advised to avoid food or activities that may trigger flushing, such as eating spicy food or drinking alcohol.

Indulge yourself in therapies that help in gaining more positive energy. If you are already affected by NET, eliminate all the sources of stress and get a good night's sleep every day. Join the support groups that make you grow strong and happy. After all, the mind is devised to do miracles when it is full of life and positive thoughts.

Is Irrfan Khan's tumour curable?

Dr Saumitra Rawat, HOD, Surgical Gastroenterology & Liver Transplant, Sri Ganga Ram Hospital, said, "NeuroEndocrine Tumour is an abnormal growth of Neuroendo cells which are present in bodies. When there is an abnormal growth, then it forms a tumor - Normally seen in intestine, pancreas, lung, thyroid and other parts of the body".

On commenting on Khan's case, he said, "It depends on the location of tumour, its size, and what is its mitotic index".

"Depending on where the tumour is localized, you can take it out surgically and the chances of cure are very high", Dr Rawat explained.

Actor Irrfan, who has been diagnosed with the disease is one of the most versatile actors in India, has also made a name for himself in the west, where he has been an important part of critically-acclaimed films such as  The Namesake ,  Jurassic World , and  Life of Pi . At home, the actor has delivered remarkable performances in films such as  Haasil ,  Paan Singh Tomar ,  Maqbool ,  Lunch Box ,  Piku , and the most recent  Hindi Medium .

Irrfan Khan is not just a disarmingly natural actor, but also an endearing human being -- honest and humble to the core. It s time to stand together and pray for him a speedy recovery!

Irrfan Khan - Battle Against Neuroendocrine Tumour!

Cancer has been regarded as one of the most deadly diseases. It is a non-communicable chronic disorder, caused by uncontrolled growth of cells in the human body. Every year over 7 million people succumb to this disease globally and over 12 million people are diagnosed with cancer. Indian Council of Medical Research (ICMR), estimated that India will observe over 8 lakh deaths and over 17 lakh new cancer cases annually by the year 2020. The survival expectancy of a cancer patient depends upon the stage of diagnosis.

There are some forms of cancer which show any noticeable symptoms only in the final stage while there are certain other subtle symptoms which if paid attention to might save a life.
Some common signs of cancer:

Unexplained weight loss: This is one of the earliest noticeable symptoms of cancer and is particularly common in patients of lung and breast cancer. Weight loss has been observed in over 40% of cancer patients at the time of diagnosis. Losing over 10% of body weight in a span of 6 months or less could be a cause of concern.
Wheezing: This is associated with lung cancer, which is also the most common form of cancer. When the airway in the lungs is pressed or narrowed by a tumor, it creates a wheezing sound while breathing.
Frequent infections: Frequent infections and fever may indicate that something is not right with the internal organs of the body. This could be because of cancerous conditions such as leukemia or lymphoma. 
Loss of appetite: Cancer impacts the metabolic process of the body, hence often leads to a loss of appetite. This is particularly a symptom of colon, stomach, ovaries and pancreatic cancer. 
Blood in stool/urine: Traces of blood while passing stool or urine could be a symptom of cancer. Though, this could be attributed to many other infections and conditions as well.
Chronic cough: Flu and cough along with symptoms like chest pain, hoarseness, weight loss and fatigue could be because of lung cancer.
Night sweats: Though night sweat could be attributed to many more reasons, it is also one of the many early warning signs of cancer.

Early Warning Signs Of Cancer That We Often Ignore!

Let s start with some mind-boggling statistics: in India, over 2.5 million patients are diagnosed with cancer. Moreover, it is estimated that around 700,000 new patients are found to have cancer, each year, and around 550,000 annual deaths are related to cancer.

While these perturbing numbers might unnerve you, there is, however, a case for cautious optimism. While there are certain causes of cancer like genetics and environment which are beyond your realms of control; there are certain causes which can be controlled by you. Research shows that nearly 70% of cancer causes are in your hands   including your own diet.

Your daily nutritional intake is vital for two reasons:

There are definite cancer-preventing nutrients and food items;
Conversely, there are certain types of nutrients and food items which cause cancer.
While research typically points to links between food items and cancer than well-established cause-effect relationships, it is found that certain dietary items have a greater influence. Here are some general guidelines to guide you better:

Avoid processed and red meat: Processed and red meat are generally considered as any meat which has been artificially modified for taste or purposes of preservation. It must be noted that during this process of preservation there are certain chemicals mixed with it which makes it carcinogenic in nature. Though the WHO (World health organization) hasn t recommended any specific amount for consumption, it has categorized processed and red meats as a Group 1   carcinogen.
Consume more fruits and vegetables: Plant foods including fruits and vegetables contain essential micronutrients like flavonoids and carotenoids which researchers  state are powerful antioxidants. Antioxidants help prevent the destruction of cells as they diminish free radicals. It is recommended to regularly consume fruits and vegetables like berries, broccoli, leafy greens, apples, papaya, among others.
Reduce your alcohol and smoking habit: Along with processed and red meats, alcohol is designated as a Group 1   carcinogen by the WHO. Cancer research has repeatedly linked consumption of alcohol to higher chances of cancer, irrespective of the alcohol type. A number of cancers including pharynx, liver, and breast are directly connected to alcohol.
Furthermore, it is suggested that an individual must limit to no more than a drink on any given day.

In conclusion, it must be stated that our diets play an indispensable role in the prevention of cancer. The consumption of healthy food items will only bolster our physical well-being along with the reduction of cancer occurrence.

How Your Diet Can Potentially Prevent Cancer?

We live in an age where every single individual, more or less, is exposed to the risk of cancer. It is probably an unfavorable lifestyle we lead that deprives us of good health. This might alarm many but considerable changes in lifestyle can help you realize cancer as a preventable disease. Cancer does not only make you undergo severe suffering but it also affects your friends and family. The pallor of misery spreads wider than you think.

Abstain from tobacco: Consuming raw tobacco or smoking tobacco can be equally detrimental to your health. Tobacco increases your chances of contracting the disease. As is known, passive smoking can also affect your health adversely. Tobacco can be the potential cause behind cancer of the mouth, throat, larynx, lungs, oral cavity and even the pancreas. It might harm your kidneys and cervix. It is upon you to quit tobacco at the earliest possible. One should also try and persuade friends and relatives to give up smoking.
Drink alcohol in moderation: Complete abstinence from alcohol might not be possible if you have already been ushered into your work- life. The society might require you to be an occasional drinker. It is important to drink in moderation. Crossing the limit can propel consequences as serious as cancer of the stomach, pancreas, liver and the heart.
A balanced and nutritious diet: Deciding on a plant- based diet or a Mediterranean diet can aid your fight against the risk of cancer. A Mediterranean diet will involve green leafy vegetables, lots of fresh fruits, whole grains, mixed nuts, legumes and also the use of extra- virgin olive oil. Fish can be a safe bet but red meat should be avoided. One must also try to avoid processed meat as they tend to make you prone to the risk of cancer.
Immunization: Hepatitis B and HPV or Human papilloma virus vaccines are extremely necessary to protect you against the sexually transmitted types of cancer.
Sun protection: Caring for your skin doesn't arise from vanity. Skin cancer is one of the most prevalent kinds of cancer; the chances of this disease can be restricted by remaining in shade especially during midday, by wearing covered clothes and by using a good sunscreen lotion repeatedly while outside.
Exercise diligently: Did you think it was okay to have weaker muscles and bulging layers of fat? If yes, you probably have grown numb to the inadequacies you face in result. Unchecked fat can lead to obesity which further complicates health conditions. Metabolic activity differs from person to person. Regular exercising can help regulate metabolism according to the needs of your body. Physical exercise protects you against the risk of breast and colon cancer. Moderate or vigorous physical activity for 150 to 75 minutes a week respectively can reduce the risk of cancer.

Reduce the Risk of Cancer - Get Tips!

Lasers have come as a boon to treat many medical conditions very safely and effectively. They are absolutely indispensable for permanent hair removal, tattoo removal, freckle removal, skin rejuvenation, treatment of birthmarks and many other internal medical conditions. There is a common misconception that lasers are harmful for your skin and can cause skin cancers. This is far from the truth, since lasers are actually used to treat skin cancers and also help in keeping the skin youthful and rejuvenated. 

Lasers use non-ionising light (like red or green light) and not ionising radiation like x-rays or gamma rays. These spectrums of light do not induce cancer formation. 
Fair skinned races are at much greater risk than skin of color. Melanin in darker skin does not allow harmful UV light in sunlight to penetrate through and the risk of skin cancers in darker skin is therefore small with normal sun exposure. Also, common lasers do not use UV light. 
Laser treatments are administered not in prolonged durations but in pulses much less than a second and parameters in the range of milliseconds and microseconds are most commonly used. Prolonged sun exposure is the most common precipitating factor for skin cancers. 
Laser light does not reach any internal organ. In fact, it requires some expertise even to make laser light reach its target just 1-2 millimeters below the skin. This is because melanin pigment in skin blocks laser light from getting through. An expert dermatologist with sound knowledge of skin optics and laser physics is able to achieve this safely and effectively. 
Laser treatments work on the principle of ''selective photothermolysis'. This means that laser light very specifically destroys only the intended target. Thus, a hair removal laser will destroy only the hair roots while leaving surrounding skin structures unharmed. Similarly, blood vessels in birth marks, collagen in wrinkles or scars, abnormal growths and cancers and individual inks in tattoos can be targeted very specifically with lasers without affecting any other structure.

Lasers - Do Not Cause Cancers!

International Childhood Cancer Day is celebrated annually on 15 February to raise awareness and to express support for children and adolescents with cancer, survivors and their families.

Why is Cancer the biggest Threat to the YOUNG in India?

There are fewer Indians who have successfully battled Cancer and have emerged successful. Yuvraj Singh, the legendary cricketer, who was diagnosed with a rare cancer at 29, survived due to an early detection. Cancer cases in India are not as many as they are in the developed world. However, due to late detection the survival rate in the country is far worse. Particularly, we are losing our youth to Cancer. Most tobacco (pan masala) related cancers and child cancers go undetected until very late.

Few cancers like cervical cancer and breast cancer which affect women of any age, are curable, however, due to lack of awareness and timely screening, many Indian women succumb to these cancers. The most common sites for cancer among men are lung, prostate, colon, rectum, stomach and liver while that among women are breast, colon, rectum, lung, cervix and stomach.

In proportion to our population, we lack the right infrastructure nationwide. esp in the northern and north eastern region, there is a dearth of good cancer facilities, where radiation, care or treatment can be given. Not even one third of cancer patients are alive beyond 5 years after their diagnosis in India, and about 71% of cancer deaths occur in patients in their prime productive years   between the ages of 30 to 69 years.

 Most Indians believe that cancer is generally incurable and that it should be kept secret from neighbors and family.  -  Dr Paul Goss, MD, Harvard University.

All these factors have contributed to a very high mortality rate. No wonder Cancer is dreaded in the country. Investment, infrastructure, lifestyles as well as mindsets need to change if we were to contain the Cancer mortality rate. While you need to watch out for early signs of cancer, here are the lifestyle changes every individual esp. all youth must adopt to avoid cancer.

Avoid Tobacco - both smoking and chewing.

Reduce alcohol intake - Save your organs from deteriorating.

Limit UV ray exposure from the sun - Keeps your skin safe.

Maintain a healthy diet - Include foods rich in Vitamins, minerals and fiber which nourish your body and build immunity.

Increase your level of fitness - Maintain a good bodyweight. Additional flab invites a host of troubles, that includes variety of cancers.

Seeking regular medical checkup or screening - This is the only way to prevent and get detected early on.

International Childhood Cancer Day - Why Cancer Is A Threat For Young?

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