Parkinson's disease is a neurodegenerative condition that affects your brain cells which produce dopamine and thus hampering all kinds of motor functioning and other emotional responses. After the disease is diagnosed, medication and therapy can help to provide relief from the symptoms to a large extent but a permanent cure is not possible.

Causes:

The disorder does not have a definite set of causes. A small percentage of the cases have been related to hereditary factors and others have a range of environmental causes associated with them.

1. Genetic factors:

Specific gene mutations and gene variations have been proved to cause Parkinson's, such as SNCA, PARK2, PARK7, PINK1 and LRRK2. These make or recycle proteins which are linked to the disease.

Research shows that men are at a 1.75 times greater risk of developing the condition than women are. Also, age plays a role with most cases occurring after the age of 60.

2. Environmental factors:

Regular exposure to inorganic insecticides, pesticides, herbicides and heavy metals or other toxins may cause the disorder. In rare cases, Parkinson's disease occurs in the aftermath of a severe head injury or immune disorders.

Symptoms:

The symptoms can be classified into two broad categories-

1. Motor symptoms:

The hand tremors when in resting position
The grip loosens
Walking slows down
Facial muscles freeze partially
Speech is slurred
Balance is disturbed
Swallowing is painful
Urination is abnormally frequent
Dementia-like symptoms are seen
There is involuntary twitching of the fingers and toes
Repetition of the same movement in quick succession is nearly impossible
2. Non-motor symptoms:

Dental problems
Vision impairment
Skin disorders
Panic attacks
Excessive secretion of saliva
Extreme weight loss or gain
Sexual problems
Loss of sense of smell
Lowering of the pitch of the voice
Fatigue

Causes and Symptoms of Parkinson's Disease

Parkinson s disease is a disorder involving the nervous system. It can start with a mere tremor of one hand and advances to slow movement and stiffness. The face might show little no symptoms in the beginning but the speech might become slurred. With every passing day, the condition worsens. This condition has no permanent cure but the symptoms can be improved with proper medication.

What are the symptoms?
Some unmistakable symptoms include the following:

A sudden shaking of the limb. A sudden tremor of the hand is a very common symptom of this disease.
A stiffness of the muscles that can limit the range of motion and sharp pain.
The posture of the body might get compromised. Often balancing problems are witnessed among many patients.
There could be problems with speech leading to soft, slurry or quick speech. The speech in some cases can become monotonous devoid of inflexions.
Parkinson s disease can lead to slow movement and makes performing of simple tasks difficult.
Patients often find writing very difficult
What are the possible causes of Parkinson s disease?

Specific genetic mutation can lead to Parkinson s disease in folks who have a family history of Parkinson s disease. Certain variations of the gene increase the risk of this disease
Exposure to certain environmental factors or certain toxins can trigger Parkinson s disease in an individual.
Certain cells in the brain known as Lewy bodies can trigger Parkinson s disease.
A certain kind of protein cells within the brain known as alpha-synuclein can trigger the Parkinson s disease in an individual
What are the risk factors?

Heredity: Having an immediate family member or a close relative suffering from Parkinson s disease can increase the risk of getting this disease in an individual
Age: Although not a prime risk factor, but an individual over the age of over 60 have an increased risk of getting this disease
Toxins: Exposure to pesticide or certain herbicide increase the risk of Parkinson s
Sex: Men are more likely to get Parkinson s disease than women
What is the medication for Parkinson s disease?

Carbidopa-levodopa: This is a natural chemical that gets passed to the brain and is converted to dopamine by the body. The benefits of this medication might reduce with increased symptoms.
Carbidopa-levodopa infusion: A popular drug in this category is known as the Duopa. It is administered directly into the small intestine in the form of gel through a feeding tube.
MAO-B inhibitors: Drugs from this group include rasagiline and selegiline. This is a powerful medicine. Many patient experiences hallucination during the initial days of consuming these drugs.
Anticholinergics: This medication is mainly used to counter tremors of the limbs in the early stage of the Parkinson s disease.

Parkinson's Disease - What Are The Risk Factors?

Parkinson s disease usually develops at a very slow rate and the early signs of this disease often go unnoticed. As the condition progresses, the symptoms become more prominent. Parkinson s disease affects the nervous system and cannot be completely cured. However, with proper treatment, its rate of progression can be slowed and this condition can be managed. The earlier a diagnosis is made, the more effective treatment will be. Thus, it is important to be able to recognize the signs the symptoms of this disease.

The signs and symptoms of Parkinson s disease vary from person to person. In most cases, symptoms begin on one side of the body and are worse on that side even after it begins to be noticed on the other side. These symptoms can include:

Tremors
Involuntary shaking of a part of the body is usually the first sign of Parkinson s the hands are most affected by this symptom. These tremors can be felt while performing an activity or even when the hand is at rest. In some cases, it can even keep a person from performing normal tasks such as writing. Tremors caused by Parkinson s can also take the form of an uncontrollable back and forth rubbing movement between the thumb and forefinger.

Slow Movements
This is also known as bradykinesia. As the disease progresses, it can slow down movement and reduce the person s ability to move. Simple tasks such as walking can become more difficult and take much longer. The person s steps may become shorter and they may also drag their feet as they walk. Parkinson s patients may also find it difficult to get in and out of chairs.

Rigidity
Parkinson s can make muscles stiff and difficult to move. This can affect the muscles of any part of the body. This rigidity can limit the person s range of movement and make moving the affected muscles very painful.

Loss of certain movements
In addition to muscle rigidity, the person may not be able to make certain movements that we take for granted. For example, he or she may not be able to blink or smile. Swinging the arms while walking may also become more difficult.

Changes to speech
Parkinson s can make a person speak slower and reduce his or her natural volume. The person s speech may also sound slurred. In addition, they may find it difficult to speak with inflections due to which their speech may appear to be monotonic.

Imbalance
Parkinson s may affect a person s posture and balance. In many cases, Parkinson s patients develop a stoop. The loss of balance can make climbing stairs difficult and cause them to fall easily.

Parkinson's Disease - Signs And Symptoms You Should Know About It!

Diagnosing dementia can be more difficult than you can imagine. Medically, the patient needs to have at least two areas of mental functionality impaired to an extent where it interferes with their everyday life. However, diagnosis is just the beginning as treating dementia can be even more challenging. Here is a look at some of the treatment options available for dementia patients.

 Treatment for Dementia
There is often no cure for most forms of dementia. Treatment relies on the management of the condition, to ensure that the progression can be impeded. With proper treatment, patients can live a relatively normal life for a number of years.

Cholinesterase inhibitors- These medications are used for the treatment of Alzheimer s disease. They are chemical agents that boost the memory and judgment of the patient. The same is also an effective medication for those suffering from Parkinson s disease and Lewy body dementia.
Therapy- Making small changes to some aspects of life of the patient can often yield good results. For instance, clearing the clutter and noise in the house can be an effective way of helping dementia patients deal with their condition. Similarly, creating a safe environment at home with little chance of severe accidents, will ensure the safety of the patient.
Stress in caregivers of dementia patients
Dementia patients need to be cared for, ideally by a close family member such as a spouse. However, these caregivers undergo a lot of stress while providing support to the patient. For instance, Alzheimer s patients often do not recognize their caregiver who may also be their spouse. Here are some burdens that caregivers have to deal with.

Anger- The sense of fury towards the patient can be strong after years of providing care. They may also be frustrated with the fact that the affected person is unable to perform simple everyday jobs, such as brushing their teeth or tying their shoelaces.
Anxiety- A sense of hopelessness regarding the future is common. It is also the fear of what new challenges the next day might bring.
Depression- Seeing their loved one s mental state deteriorating with each passing day can be difficult to handle and pushes some caregivers into depression.
With such continuous emotional and physical stress, caregivers often fall sick themselves. This is why it is necessary to maintain a bright outlook and remember that a dementia patient can only get well if they have the full support of the caregiver. In case you have a concern or query you can always consult an expert & get answers to your questions!

Treating Dementia - Things You Should Know!

Ageing is inevitable, and as much as we want to escape, there is no way out. All organs, whether obvious or not, undergo gradual degeneration and deterioration. The brain is no exception, and memory being one of its main function also begins to decline with age. There are various factors which determine how quickly this ageing sets in and how rapidly it progresses. These are dictated by a person s lifestyle, activity levels, and overall body changes. Dementia also has a strong family history, and if you know someone who has a family history, there are some early signs that you could watch for. This will help in both empathizing with the person, as well as to help in arresting progression. Read on to know the signs that need to be watched out for.

Mood changes: Sudden changes in mood, especially going into short periods of depression without an obvious reason, is one of the first symptoms of dementia. If it is happening repeatedly, this can help identify dementia.
Personality changes: If a shy person suddenly becomes outgoing or vice versa, this could be an early indicator of dementia. They either develop or shed inhibitions, which is a new change for them.
Memory loss: Sudden short-term memory loss for a person who had a very strong memory is a definite indicator of dementia. They might clearly remember the distant events but forget small things like where to find their medicines, where things are in the kitchen or bathroom, etc. Because of this, you might see them repeating what they just did. This could be like washing a glass again, saying or asking the same thing again, etc.
The difficulty with regular tasks: Short-term memory loss causes difficulty with regular tasks like laying out the dinner table, finding regular medicines, paying utility bills, etc. There is also difficulty in learning new tasks, which further complicates things.
Feeling lost: Due to sudden memory loss and difficulty with regular tasks, they suddenly feel lost, which in turns adds to their depression.
Apathy: This also leads to a general lack of interest in things and people around them. They could have had hobbies, which no longer interest them.
Disoriented: They find it difficult to be aligned to time and space. Directions which they clearly know could seem difficult.
Not able to connect the dots: While the elderly people are generally good at telling stories and anecdotes, with dementia setting in, this becomes difficult.
These are some symptoms which can help identify if a near one is slowly developing dementia. Identifying in the early stages can help in arresting progress and extending support.

Dementia - How To Know If Someone Is Suffering From It?

Neurology is the branch of science and medicine dealing with the central and peripheral nervous system. The nervous system is made of the brain and spinal cord. The disorders, illness or injuries of the nervous system can become problematic for people suffering from them. One of the worst diseases of the nervous system is Parkinson s disease.

It is a progressive disorder affecting the central nervous system that leads to slowing down of movement and slurring of speech over a period of time. It is a condition where the nerve cells in the brain producing dopamine (a neurotransmitter) are affected.

Some of the early signs of Parkinson s include:

Tremor: If you have noticed a slight shaking of your hands or limbs, then Parkinson s might be the cause. The trembling can range from mild to severe as the disease progresses. The back-and-forth rubbing of your thumb and forefinger is known as pill-rolling tremor. One of the most prominent signs is your hand shaking even when it is rested.
Bradykinesia (slow movement): As the disease progresses, you may find it difficult to move your hands or legs or going from one place to another. Even making the smallest movement will require an increased effort on your part.
Rigid Muscles: The muscles in your body can become stiff causing you pain and making it difficult to perform physical activities.
Masked Face: Your face may experience spasms or become stiff periodically. It can also lead to complete paralysis on one side of the face.
Stooping or improper balance: Having Parkinson s disease can make your body posture imbalanced resulting in stooping or hunching over.
Decreased Automatic Movements: You may experience difficulty in smiling, blinking or swinging your arms while walking.
Alteration in voice or speaking: Your voice can become soft or you may slur while talking. You can also experience a monotonous voice.
Writing may become small: You can experience changes in your handwriting as it becomes small and crowded.
Loss of Smell: The smell of food sitting right in front of you may not register in your olfactory resulting in loss of appetite.
Constipation: Having Parkinson s disease can lead to patients experiencing irritable bowel syndrome.
Have Trouble Sleeping: It might be difficult to fall asleep for people suffering from Parkinson s. Also, there are sudden movements during the sleeping process.
Dizziness: People suffering from Parkinson s may faint from time to time.
These were some of the symptoms and signs by which you can tell whether a person has Parkinson s or not. However, as of now it is not curable and can only be treated with medicines. But, early detection can definitely help in preventing it from affecting the whole body.

Parkinson's Disease - Are You Aware Of These Signs?

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