Alzheimer's disease is a neurological problem that is characterised by a cognitive decline and memory loss. It is a type of neurodegenerative dementia. The symptoms of alzheimer's disease include not being able to absorb and retain new information, lack of reasoning and judging, not being able to take on complex tasks, impaired visuospatial abilities, problems in reading, writing and speech, among many others. If a person has at least two of these symptoms in a debilitating manner, then the diagnosis can be made in favour of alzheimer's disease. The main causes of alzheimer's are shrinkage of the brain size and death of the brain cells. The immune system is also said to trigger this neurodegenerative disease. Let us find out what medical science has found so far.

1. Connections: many a times, in alzheimer's disease, the memory and behaviour of the person changes because the brain is unable to make proper neural connections which can lead to memory loss of how a person behaved and the elements that formed the basis of the patient's cognition. Apparently, the immune system behaves in the same way within the brain and blocks the connection. This happens because there is constant communication between the brain and immune system along neurological lines, which is where the disease first emanates.

2. Inflammation: the brain is prone to inflammation or swelling that is not the normal kind. This inflammation happens as a result of the activation of the infection fighting neurotransmitters and the chemical changes that happen in the brain when an infection strikes. The inflammation usually happens in the plaques or clumps which the brain tries to protect. These clumps are made up of a protein called amyloid. The immune system is responsible for creating this inflammation in the brain of the patient.

3. Pattern recognition receptors: many of these receptors work in different manners and cooperate with each other to create a response in the brain. These prrs can be found in the brain plaques, and they develop the signs of danger which further fuels the inflammation in the brain as a matter of protection.

4. Activation of cells linked with the immune system: when the prrs begin to respond, it basically activates the immune system and the cells of the same. This is the basic reaction that causes the changes in brain which then leads to the attachment of the protein to the tissue that is diseased, in which case alzheimer's disease starts. The inflammation that we had spoken about earlier basically happens in the nervous tissue.

It is important to recognise and act on the initial signs of alzheimer's disease before it progresses beyond one's control.

Can the Immune System Trigger Alzheimer's Disease

What is Parkinson s disease?
Parkinson s disease is a progressive and degenerative disorder of the Central Nervous System that mostly affects older people. It is a chronic disease and the symptoms develop over a period of time. The characteristic symptoms of Parkinson s are rigidity, shaking, bradykinesia (slowness in movement) and shuffled gait. Anxiety and depression also seem to be common in advanced stages of Parkinson s disease. In addition to the motor symptoms, the cognitive function of the brain is also compromised.

Degeneration of the nerve cells in the substantia nigra of the brain results in the reduction in production of dopamine which is a neurotransmitter in the brain. Neurotransmitters relay impulses from one nerve to the other. This is what is mainly responsible for the motor symptoms in Parkinson s. Although, Parkinson s is not a curable disease, it can be controlled and the progress of the disease can be kept in check with certain medications.

What causes Parkinson s disease?
The cause of Parkinson s is mostly idiopathic, i.e. the cause is unknown and is not specific. However, there have been cases which show that it can be attributed to factors such as genetic and environmental factors.
What are the symptoms of Parkinson s?

The symptoms of Parkinson s can be classified as Motor symptoms and Non-motor symptoms:

Motor Symptoms 

Bradykinesia: Slow movement
Tremor of limbs
Rigidity or stiffness of trunk and limbs
Impaired balance and difficulty in coordination or postural instability
Non-motor Symptoms 

Depression
Anxiety and fear
Loss of energy and fatigue
Constipation
Excessive salivation
Weight gain or weight loss
Cognitive problems such as difficulty in remembering, confusion, dementia
Parkinson s disease is not curable, but when detected early, medicines are prescribed to give symptomatic relief. Dopamine substitutes are prescribed to the patient to relieve the motor symptoms.

Parkinson's Disease - Understanding The Motor & Non-motor Symptoms!

Firstly, what you need to realise is that Alzheimer s is not dementia and the main point you need to remember about the difference between the two is that the former is a disease while the latter is a syndrome. Alzheimer s is a neurodegenerative disease, it breaks down the cognitive functions of the brain and reduces a person s ability to function properly. It s one of the foremost reasons for untimely senility in middle-aged to old-aged persons.

It can be a scary time for the patient themselves as well as for friends and family alike but fear not, there are ways to reduce the chances of suffering from this painful predicament. Here are a few easy hacks to keep in mind to stave off the risk of Alzheimer s:

Fix your diet: Cut down on saturated fats and construct a diet combining lots of healthy vitamin and mineral rich foods, fruits and vegetables. Vitamin E is essential as well as vitamin B12 which can also be taken in the form of supplements. Vitamin E can be found in foods like spinach and even nuts. Rush University Medical Centre in Chicago has, after a lot of research, developed the MIND and DASH diets. The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet collates portions of the DASH (Dietary Approaches to Stop Hypertension) diet to create the perfect combination that has been shown to reduce the risk of Alzheimer s by 53 percent.
Exercise mental and physical: A sedentary lifestyle is one of the major causes of Alzheimer s because it leads to slower brain activity and an overall unhealthy lifestyle. To break out of this you need to regularly exercise and not just physical exercises but also mental exercises such as solving mental maths and crosswords and reading books and newspapers. There are a lot of apps concerning games that help boost brain activity on the market that can help as well. Physical exercise can include swimming, brisk walking, joking and even gardening.
Reduce stress: Stress proves to be a huge issue for the brain contributing to its damage by putting a lot of pressure on it. Try to relax more by improving your sleep cycle, resting as and when required, and not overworking yourself.
Aromatherapy: Essential oils have been shown to work wonders, by reducing stress and relaxing the mind. Lavender, rosemary, lemon and even orange are some great options you can try out. These oils can help rejuvenate damaged brain and nerve cells.
Meditation: Studies have shown that regular meditation helps boost grey matter in the brain, and along with yoga, keeps the minds and bodies of middle-aged people active and better focused contributing to the overall health of the brain.

Life Hacks! How To Beat Alzheimer's

The skin is an elastic organ (yes, it is an organ!), but only to a certain extent. It has a limit to which it can accommodate the underlying tissues. With the increase in bulk, for example, puberty, pregnancy, muscle mass building or surgical implants, the skin is made to stretch beyond its limits. What happens is this stretch causes the skin to stretch too, and these stretch marks or striae become an unpleasant thing that needs to be hidden. 

Dressing needs to be changed so that they are not showing. Dermatologists see a big demand for getting rid of these marks too. There have been conventional, time-tested methods which help in getting rid of these. However, with newer advancements in dermatology, the platelet rich plasma is being widely used for getting rid of these stretch marks.

Why stretch marks? 

In any of the scenarios above, the stretch marks appear because there is a lack of underlying supportive tissue when it is stretched out. There is a lack of collagen and connective tissue, causing stretch marks. These are most evident in fat collecting areas like breasts, abdomen, thighs, upper arms, etc.

What is platelet-rich plasma or PRP? 

The blood is composed of a liquid portion known as plasma, which contains three main types of cells i.e. white blood cells, red blood cells, and platelets. The white blood cells are the ones responsible for fighting infections. The red cells give blood its color and also are responsible for carrying nutrients to the various organs. The platelets are tiny fragments of cells which help in blood clotting. Platelets are also rich in what are called totipotent cells, which can grow into any type of cells. When the body is affected, due to injury, infection, trauma, etc., these get concentrated in the affected area and are produced in large numbers to help in the recovery of the particular affected area.

Technique: 

The area to be treated is isolated and prepared. Blood is centrifuged to remove other cells and obtain platelet rich plasma. This RPR is injected into the underlying layers of the skin. This induces the release of growth factors into the connective tissue space. Collagen is produced over a period of time, which causes the skin to become taut and lose the stretch marks. The injection can be repeated if required on the topmost layer. It can also be mixed with thrombin to form a gel, which is then used similarly. Using it both in the underlying and superficial layers helps in completely getting rid of the marks.

Studies have shown a reduction in both the depth and size of the stretch marks and some might require two to three repeat injections.


Stretch Marks - How PRP Therapy Can Help You?

Alzheimer s disease is a neurological, irreversible, progressive brain disorder. It is a chronic neurodegenerative dementia that causes the death of brain cells, causing memory loss and cognitive decline. It affects a person s thinking and behavior. The symptoms develop slowly and get worse as time passes.

Causes:
As it is a kind of dementia, Alzheimer s is caused by the death of brain cells. Over a course of time, brain cells die progressively and at the end, the tissue is left with fewer nerve cells and connections. As a result, the total brain size shrinks. Tiny inclusions called plaques and tangles can be seen in the postmortem. These cannot be seen or tested in a living Alzheimer s affected brain. These plaques are given the name  amyloid plaques  because they are found among the dying cells of the brain when a protein called beta-amyloid builds. The tangles stay in the neurons; they are formed from a protein called tau.

There are several reasons behind all this, some of which are listed below-

Anti-anxiety medications
Hitting on the head too many times
Regularly sleep-deprived
Loneliness
Diabetes in the brain
Old age
Genetic line
Down s syndrome
Cardiovascular diseases
Symptoms:
Alzheimer s disease damages the brain, so the clinical signs and symptoms begin to show very early. The symptoms are-

Memory loss
Agitation and mood swings
Poor judgment
The trouble with money calculations
Difficulty doing familiar tasks
Trouble in planning or solving a problem
Confusion with time and place
Difficulty in communicating
Loss of motivation
Inappropriate behavior
Aggressive personality
Childlike behavior
Preventing Alzheimer s disease:
Alzheimer s disease ultimately results in death. Even if there are treatments, they cannot fully cure it. So it s better to try to prevent it before it happens. Ways to prevent Alzheimer s disease are-

Eating more fruits and vegetables.
Eating berries every day.
Increasing omega-3 fatty acids.
Taking folic acid supplements.
Drinking grape juice or red wine with evening meal.
Doing the Mediterranean style diet.
Controlling the blood pressure.
Having strong social support.
Treatment of Alzheimer s disease:

Treatment of Alzheimer s disease is a long time process.
First of all, doctors perform a physical exam to check the overall neurological health. By this, they check muscle strength, reflexes, walking ability, sense of sight and hearing, coordination and balance.
Then comes the blood test to find the cause of confusion and memory loss by checking the thyroid disorder and vitamin deficiency.
Then they perform the neuropsychological test and check the mental status.
Then there are other tests, like MRI, CT, and PET.
After all this, drugs are given and a safe and supportive environment is created with proper exercise and nutrition.
Alzheimer s disease is undoubtedly the worst kind of disease. Hence, it is highly recommended to contact a doctor as soon as any symptom is noticed.

All About Alzheimer's Disease!

Diagnosing dementia can be more difficult than you can imagine. Medically, the patient needs to have at least two areas of mental functionality impaired to an extent where it interferes with their everyday life. However, diagnosis is just the beginning as treating dementia can be even more challenging. Here is a look at some of the treatment options available for dementia patients.

 Treatment for Dementia
There is often no cure for most forms of dementia. Treatment relies on the management of the condition, to ensure that the progression can be impeded. With proper treatment, patients can live a relatively normal life for a number of years.

Cholinesterase inhibitors- These medications are used for the treatment of Alzheimer s disease. They are chemical agents that boost the memory and judgment of the patient. The same is also an effective medication for those suffering from Parkinson s disease and Lewy body dementia.
Therapy- Making small changes to some aspects of life of the patient can often yield good results. For instance, clearing the clutter and noise in the house can be an effective way of helping dementia patients deal with their condition. Similarly, creating a safe environment at home with little chance of severe accidents, will ensure the safety of the patient.
Stress in caregivers of dementia patients
Dementia patients need to be cared for, ideally by a close family member such as a spouse. However, these caregivers undergo a lot of stress while providing support to the patient. For instance, Alzheimer s patients often do not recognize their caregiver who may also be their spouse. Here are some burdens that caregivers have to deal with.

Anger- The sense of fury towards the patient can be strong after years of providing care. They may also be frustrated with the fact that the affected person is unable to perform simple everyday jobs, such as brushing their teeth or tying their shoelaces.
Anxiety- A sense of hopelessness regarding the future is common. It is also the fear of what new challenges the next day might bring.
Depression- Seeing their loved one s mental state deteriorating with each passing day can be difficult to handle and pushes some caregivers into depression.
With such continuous emotional and physical stress, caregivers often fall sick themselves. This is why it is necessary to maintain a bright outlook and remember that a dementia patient can only get well if they have the full support of the caregiver. In case you have a concern or query you can always consult an expert & get answers to your questions!

Treating Dementia - Things You Should Know!

Don't wait any longer, manage your Neurodegeneration online with a Lybrate doctor today

Consult for Neurodegeneration - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES