Depression is possibly regarded as the first sign of Alzheimer s disease. According to a research, the connection between Alzheimer s disease and depression is very interesting. It has been found that the life of people who are suffering from dementia is affected in 2 different ways. Individuals who have suffered from depression in their lives are at a greater risk of developing dementia. It has also been observed that people suffering from dementia also have depression. The health condition should be treated immediately because if it is ignored it can damage the quality of life and result in worst conditions like memory loss. Temperament, as well as behavioral changes, may precede memory problems in people with the disease.

Risk factor of dementia
The significant risk factor for dementia or common form of Alzheimer s is developing depression at a younger age. The other reasons for the link are not very clear, however, it has been speculated that the inflammation that occurs in depression is a contributing factor to the Alzheimer s disease. The risk of dementia also increases with certain proteins which spiral with depression. The common signs of Alzheimer s disease include lack of appetite, sadness, agitation, weight loss, and anxiety. People suffering from this condition are unable to tell if they are depressed, but their actions help in communicating a message. It is always better to seek the assistance of a physician as doctors can make use of tools to assess the neurological disorder.

Best way to treat patients with Alzheimer s
The best way to treat patients suffering from dementia and who are depressed is to engage them in activities. It is important that they step out and do some exercises. They should go out in the sunshine. It is necessary to engage them in activities and conversations and help them to lead a higher quality of life. Some of the symptoms of dementia and depression are alike but not all of them. The major symptoms of depression include feeling tired most of the times, feeling restless, irritable, feeling worthless/guilty, unplanned weight gain and trouble in focusing. These symptoms often occur for more than 2 weeks or longer.

Difficulties caused by Alzheimer s disease
In the case of Alzheimer s disease, it becomes very difficult for the individual to communicate, learn or remember mainly because the damage is caused to the brain. Due to the brain damage, there is a possibility of changes in the personality and moods of individuals suffering from this health condition. The quality of life is affected by depression as well as Alzheimer s disease. Hence, it is always better to treat the condition immediately. For that reason, it is very important to set up a pleasant environment around and help patients suffering from this condition by helping them do enjoyable tasks and make them feel positive about life.

Alzheimer's Disease & Depression - How They Are Related?

What is Parkinson s disease?
Parkinson s disease is a progressive and degenerative disorder of the Central Nervous System that mostly affects older people. It is a chronic disease and the symptoms develop over a period of time. The characteristic symptoms of Parkinson s are rigidity, shaking, bradykinesia (slowness in movement) and shuffled gait. Anxiety and depression also seem to be common in advanced stages of Parkinson s disease. In addition to the motor symptoms, the cognitive function of the brain is also compromised.

Degeneration of the nerve cells in the substantia nigra of the brain results in the reduction in production of dopamine which is a neurotransmitter in the brain. Neurotransmitters relay impulses from one nerve to the other. This is what is mainly responsible for the motor symptoms in Parkinson s. Although, Parkinson s is not a curable disease, it can be controlled and the progress of the disease can be kept in check with certain medications.

What causes Parkinson s disease?
The cause of Parkinson s is mostly idiopathic, i.e. the cause is unknown and is not specific. However, there have been cases which show that it can be attributed to factors such as genetic and environmental factors.
What are the symptoms of Parkinson s?

The symptoms of Parkinson s can be classified as Motor symptoms and Non-motor symptoms:

Motor Symptoms 

Bradykinesia: Slow movement
Tremor of limbs
Rigidity or stiffness of trunk and limbs
Impaired balance and difficulty in coordination or postural instability
Non-motor Symptoms 

Depression
Anxiety and fear
Loss of energy and fatigue
Constipation
Excessive salivation
Weight gain or weight loss
Cognitive problems such as difficulty in remembering, confusion, dementia
Parkinson s disease is not curable, but when detected early, medicines are prescribed to give symptomatic relief. Dopamine substitutes are prescribed to the patient to relieve the motor symptoms.

Parkinson's Disease - Understanding The Motor & Non-motor Symptoms!

Alzheimer's disease is a dynamic disease that causes loss of memory and other vital mental functions. To start with, someone with Alzheimer's disease may witness light confusion in the beginning and trouble recalling. In the long run, individuals with the disease may even overlook important individuals in their lives and experience emotional identity changes.

Dementia: Alzheimer s disease is the most widely recognised reason for dementia   a gathering of brain issues that causes the loss of intellectual and social abilities. In Alzheimer's disease, the brain cells deteriorate and die, bringing on an enduring decrease in memory and mental capacity.
Brain Cells: Despite the fact that the reasons for Alzheimer's is not yet completely comprehended, its impact on the brain is clear. Alzheimer's disease harms the brain cells. A mind influenced by Alzheimer's has fewer cells and fewer associations among surviving cells than a solid mind.
Brain Shrinkage: As more brain cells start to die, Alzheimer's prompts critical brain shrinkage. At the point when specialists inspect Alzheimer's brain tissue under the magnifying instrument, they see two sorts of irregularities that are considered to cause Alzheimer s. These are:
Plaque: These clusters of a protein called beta-amyloid may harm and crush brain cells in a few ways, meddling with cell-to-cell functioning. In spite of the fact that a definitive reason for brain cell passing in Alzheimer's is not known, the accumulation of beta-amyloid on the outside of brain cells is a prime reason.
Tangles: Brain cells rely upon an inner support and transport framework to carry the supplements and other fundamental materials through their long extensions. This framework requires the typical structure and working of a protein called tau. In Alzheimer's, strings of tau protein turn into strange tangles inside the brain cells. This may also cause the decrease of brain cells. 
Here are some more causes that can lead to this disease:

Age: Age is a most critical cause in the development of Alzheimer's disease. The probability of building up the condition increases after you reach sixty-five years of age.
Family history: The qualities you acquire from your parents can add to your danger of building up Alzheimer's infection. This may also contribute to the environmental factors which can cause this condition. In some families, a single gene creates Alzheimer s disease and the dangers of the condition being passed on are much higher.
Head injuries: Individuals who have had serious head damage have been observed to be at higher risk of building up Alzheimer's disease.
Cardiovascular diseases: Research demonstrates that few lifestyle components and conditions connected with cardiovascular disease can build the danger of Alzheimer's disease. These include smoking, obesity, diabetes, hypertension and high cholesterol.


Alzheimer's Disease - Reasons That Can Lead To It!

With age, most body organs begin to deteriorate in their function. This happens to the brain also, thereby reducing the overall speed of functioning of most organs. While slowing of bodily movement is visible, the internal organs functioning also slows down, which is not that obvious. Memory loss or dementia is one of the main manifestations of this degeneration of the brain.

Alzheimer s is the most common form of dementia, and the associated symptoms includes reduced reasoning abilities and cognitive defects. Though it is seen only in the elderly, not all elderly people will have Alzheimer s. The overall quality of life of the affected person is reduced with difficulty remembering things that were recently learned. It is a progressive disease and as it gets more severe, a full-time caretaker may be required.

Causes: The brain cells are affected by protein masses known as plaques and tangles. These hamper the way communication between the brain cells happens as well as affect nutrition from reaching all parts of the brain. This leads to shrinking of the brain, eventually leading to memory loss and other problems. There is also a strong genetic linkage, as most people with Alzheimer s have the lipoprotein A gene.

Symptoms: Though memory loss is the most common symptom, there are other symptoms:

Being confused about places, people, and times
Inability to find the right words during conversations
Regular objects are misplaced
Becoming irritable, (in someone who was not so previously)
Mood swings
Personality changes
Inability to organise thoughts
Not able to make the right decisions
Repetitive talks and actions
Forgetfulness (not something the person always does)
Difficulty with numbers (again, not something calculations
Difficulty managing everyday tasks and minor problems
Suspicion of others (like immediate family members and friends)
Risk factors: While age is definitely a risk factor, the fact that not all aged people develop Alzheimer s is to be borne in mind. Other risk factors include the history of stroke, high cholesterol, high blood pressure, diabetes, smoking, obesity, and poor lifestyle choices.

Diagnosis: While there is no definitive way to diagnose Alzheimer s, symptoms along with brain scans and neuropsychological function testing are useful ways to confirm the diagnosis.

Treatment: This is aimed at two things reducing the rate of disease progression and treat (or reverse) symptoms if possible.

Cholinesterase inhibitors improve cellular communication in the brain and also manage depression and agitation. Memantine is used to slow the pace of disease progression.
In people with the disease, small changes are useful to help them with the symptoms. These include keeping essential things like keys and wallet in the same place, keep a daily diary to help them remember things, keep pictures of friends and family within visible distance.

Alzheimer's - An Overview!

The skin is an elastic organ (yes, it is an organ!), but only to a certain extent. It has a limit to which it can accommodate the underlying tissues. With the increase in bulk, for example, puberty, pregnancy, muscle mass building or surgical implants, the skin is made to stretch beyond its limits. What happens is this stretch causes the skin to stretch too, and these stretch marks or striae become an unpleasant thing that needs to be hidden. 

Dressing needs to be changed so that they are not showing. Dermatologists see a big demand for getting rid of these marks too. There have been conventional, time-tested methods which help in getting rid of these. However, with newer advancements in dermatology, the platelet rich plasma is being widely used for getting rid of these stretch marks.

Why stretch marks? 

In any of the scenarios above, the stretch marks appear because there is a lack of underlying supportive tissue when it is stretched out. There is a lack of collagen and connective tissue, causing stretch marks. These are most evident in fat collecting areas like breasts, abdomen, thighs, upper arms, etc.

What is platelet-rich plasma or PRP? 

The blood is composed of a liquid portion known as plasma, which contains three main types of cells i.e. white blood cells, red blood cells, and platelets. The white blood cells are the ones responsible for fighting infections. The red cells give blood its color and also are responsible for carrying nutrients to the various organs. The platelets are tiny fragments of cells which help in blood clotting. Platelets are also rich in what are called totipotent cells, which can grow into any type of cells. When the body is affected, due to injury, infection, trauma, etc., these get concentrated in the affected area and are produced in large numbers to help in the recovery of the particular affected area.

Technique: 

The area to be treated is isolated and prepared. Blood is centrifuged to remove other cells and obtain platelet rich plasma. This RPR is injected into the underlying layers of the skin. This induces the release of growth factors into the connective tissue space. Collagen is produced over a period of time, which causes the skin to become taut and lose the stretch marks. The injection can be repeated if required on the topmost layer. It can also be mixed with thrombin to form a gel, which is then used similarly. Using it both in the underlying and superficial layers helps in completely getting rid of the marks.

Studies have shown a reduction in both the depth and size of the stretch marks and some might require two to three repeat injections.


Stretch Marks - How PRP Therapy Can Help You?

Ageing is inevitable, and as much as we want to escape, there is no way out. All organs, whether obvious or not, undergo gradual degeneration and deterioration. The brain is no exception, and memory being one of its main function also begins to decline with age. There are various factors which determine how quickly this ageing sets in and how rapidly it progresses. These are dictated by a person s lifestyle, activity levels, and overall body changes. Dementia also has a strong family history, and if you know someone who has a family history, there are some early signs that you could watch for. This will help in both empathizing with the person, as well as to help in arresting progression. Read on to know the signs that need to be watched out for.

Mood changes: Sudden changes in mood, especially going into short periods of depression without an obvious reason, is one of the first symptoms of dementia. If it is happening repeatedly, this can help identify dementia.
Personality changes: If a shy person suddenly becomes outgoing or vice versa, this could be an early indicator of dementia. They either develop or shed inhibitions, which is a new change for them.
Memory loss: Sudden short-term memory loss for a person who had a very strong memory is a definite indicator of dementia. They might clearly remember the distant events but forget small things like where to find their medicines, where things are in the kitchen or bathroom, etc. Because of this, you might see them repeating what they just did. This could be like washing a glass again, saying or asking the same thing again, etc.
The difficulty with regular tasks: Short-term memory loss causes difficulty with regular tasks like laying out the dinner table, finding regular medicines, paying utility bills, etc. There is also difficulty in learning new tasks, which further complicates things.
Feeling lost: Due to sudden memory loss and difficulty with regular tasks, they suddenly feel lost, which in turns adds to their depression.
Apathy: This also leads to a general lack of interest in things and people around them. They could have had hobbies, which no longer interest them.
Disoriented: They find it difficult to be aligned to time and space. Directions which they clearly know could seem difficult.
Not able to connect the dots: While the elderly people are generally good at telling stories and anecdotes, with dementia setting in, this becomes difficult.
These are some symptoms which can help identify if a near one is slowly developing dementia. Identifying in the early stages can help in arresting progress and extending support.

Dementia - How To Know If Someone Is Suffering From It?

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