One of the worst neurological disorders to have is dementia. It is a general term used to describe cognitive decline of the brain. It s not specific disease but denotes several brain disorders and mental illnesses. A person suffering from dementia can have severe impairment in judgment, loss of memory and thinking. Dementia is a very difficult disease not only for the patient but also for their families and caregivers. 

Some facts about dementia are as follows:

It s not a mental disorder occurring in old age but it does degenerates with age.
An estimation of 47.5 million people worldwide suffers from dementia and 60% of these people live in low and middle-income countries and according to WHO this figure is likely to increase.
Every 4 seconds a new case of dementia is reported
Dementia is a collective term to describe the many types of in people, such as 

Alzheimer s Disease: It is one of the most common type of dementia accounting for 60-80% of dementia case. People suffering from Alzheimer s have fewer nerve cells and the size of the brain shrinks.
Vascular Dementia: Another most common form of dementia occurring after a stroke.
Lewy Body Dementia: It is neurodegenerative condition that involves a protein called alpha-synuclein which changes the brain. Symptoms may be similar to Parkinson s disease.
Symptoms of dementia can range from mild to moderate to severe that includes:

Memory Loss
Disorientation meaning inability to focus or pay attention
Changes in visual perception
Impairment in reasoning and judgment
Dementia can be caused by damage to brain cells or progressive brain cell death. As a result communication between brain cells become difficult. Other symptoms include:

Stroke
Brain Tumor
Head Injury
Prion Disease
HIV Infection
Reversible Factors

There are no definite tests for dementia. Doctors and neurologists have to medical history, blood tests and CT scans to find out whether a person has dementia or not. However, the most potent evaluation comes from a set of questions that are asked to a patient suspected of having dementia. The ability to answer those questions correctly is one of the best diagnoses for dementia.
There is no specific treatment for dementia as it is not a curable disease and degenerates with time. However, medicines or drugs given for Alzheimer s can be given to people suffering from dementia.
Although results vary depending upon a person s lifestyle s and habits, doctors suggest eating healthy, exercising regularly, and stopping smoking and drinking may prevent some types of dementia.
The best treatment for dementia is to treat the person with care and love so that they don t feel neglected.
Dementia is often associated with old age but that is not always true. It is important to gain knowledge and educate others also.

Dementia - Quick Facts You Must Know About It!

Parkinson s disease is a disorder involving the nervous system. It can start with a mere tremor of one hand and advances to slow movement and stiffness. The face might show little no symptoms in the beginning but the speech might become slurred. With every passing day, the condition worsens. This condition has no permanent cure but the symptoms can be improved with proper medication.

What are the symptoms?
Some unmistakable symptoms include the following:

A sudden shaking of the limb. A sudden tremor of the hand is a very common symptom of this disease.
A stiffness of the muscles that can limit the range of motion and sharp pain.
The posture of the body might get compromised. Often balancing problems are witnessed among many patients.
There could be problems with speech leading to soft, slurry or quick speech. The speech in some cases can become monotonous devoid of inflexions.
Parkinson s disease can lead to slow movement and makes performing of simple tasks difficult.
Patients often find writing very difficult
What are the possible causes of Parkinson s disease?

Specific genetic mutation can lead to Parkinson s disease in folks who have a family history of Parkinson s disease. Certain variations of the gene increase the risk of this disease
Exposure to certain environmental factors or certain toxins can trigger Parkinson s disease in an individual.
Certain cells in the brain known as Lewy bodies can trigger Parkinson s disease.
A certain kind of protein cells within the brain known as alpha-synuclein can trigger the Parkinson s disease in an individual
What are the risk factors?

Heredity: Having an immediate family member or a close relative suffering from Parkinson s disease can increase the risk of getting this disease in an individual
Age: Although not a prime risk factor, but an individual over the age of over 60 have an increased risk of getting this disease
Toxins: Exposure to pesticide or certain herbicide increase the risk of Parkinson s
Sex: Men are more likely to get Parkinson s disease than women
What is the medication for Parkinson s disease?

Carbidopa-levodopa: This is a natural chemical that gets passed to the brain and is converted to dopamine by the body. The benefits of this medication might reduce with increased symptoms.
Carbidopa-levodopa infusion: A popular drug in this category is known as the Duopa. It is administered directly into the small intestine in the form of gel through a feeding tube.
MAO-B inhibitors: Drugs from this group include rasagiline and selegiline. This is a powerful medicine. Many patient experiences hallucination during the initial days of consuming these drugs.
Anticholinergics: This medication is mainly used to counter tremors of the limbs in the early stage of the Parkinson s disease.

Parkinson's Disease - What Are The Risk Factors?

Alzheimer's disease is a dynamic disease that causes loss of memory and other vital mental functions. To start with, someone with Alzheimer's disease may witness light confusion in the beginning and trouble recalling. In the long run, individuals with the disease may even overlook important individuals in their lives and experience emotional identity changes.

Dementia: Alzheimer s disease is the most widely recognised reason for dementia   a gathering of brain issues that causes the loss of intellectual and social abilities. In Alzheimer's disease, the brain cells deteriorate and die, bringing on an enduring decrease in memory and mental capacity.
Brain Cells: Despite the fact that the reasons for Alzheimer's is not yet completely comprehended, its impact on the brain is clear. Alzheimer's disease harms the brain cells. A mind influenced by Alzheimer's has fewer cells and fewer associations among surviving cells than a solid mind.
Brain Shrinkage: As more brain cells start to die, Alzheimer's prompts critical brain shrinkage. At the point when specialists inspect Alzheimer's brain tissue under the magnifying instrument, they see two sorts of irregularities that are considered to cause Alzheimer s. These are:
Plaque: These clusters of a protein called beta-amyloid may harm and crush brain cells in a few ways, meddling with cell-to-cell functioning. In spite of the fact that a definitive reason for brain cell passing in Alzheimer's is not known, the accumulation of beta-amyloid on the outside of brain cells is a prime reason.
Tangles: Brain cells rely upon an inner support and transport framework to carry the supplements and other fundamental materials through their long extensions. This framework requires the typical structure and working of a protein called tau. In Alzheimer's, strings of tau protein turn into strange tangles inside the brain cells. This may also cause the decrease of brain cells. 
Here are some more causes that can lead to this disease:

Age: Age is a most critical cause in the development of Alzheimer's disease. The probability of building up the condition increases after you reach sixty-five years of age.
Family history: The qualities you acquire from your parents can add to your danger of building up Alzheimer's infection. This may also contribute to the environmental factors which can cause this condition. In some families, a single gene creates Alzheimer s disease and the dangers of the condition being passed on are much higher.
Head injuries: Individuals who have had serious head damage have been observed to be at higher risk of building up Alzheimer's disease.
Cardiovascular diseases: Research demonstrates that few lifestyle components and conditions connected with cardiovascular disease can build the danger of Alzheimer's disease. These include smoking, obesity, diabetes, hypertension and high cholesterol.


Alzheimer's Disease - Reasons That Can Lead To It!

Dementia cannot be singularly regarded as a specific disease, but rather indicates a group of symptoms associated with your memory, cognitive thinking, and social abilities, up to the point where daily functioning gets affected. In most cases, dementia steadily worsens over time (progressive dementias). Dementia is not to be confused with memory loss alone; because it is natural with old people to experience memory loss, but that does not necessarily mean they have dementia. If the reason is dementia, then you may require medical treatment.

Causes

Dementias are generally caused either by damage to or changes in the nerve cells operating in the brain. The causes can be grouped differently based on the type of dementia experienced and the part of the brain affected. While some causes can be reversed with effective treatment, others, unfortunately, cannot.

The most common causes of dementia which cannot be reversed include:

1. Alzheimer's disease
2. Vascular dementia
3. Parkinson's disease
4. Frontotemporal dementia
5. Dementia with Lewy (dementia which is neurodegenerative and progressive in nature) bodies
6. Severe head injuries

Other irreversible causes which are relatively rarer than usual include:

1. Huntington's disease (breakage of the brain's nerve cells)
2. Creutzfeldt-jakob disease (irreversible and fatal brain disease)
3. Multiple sclerosis or amyotrophic lateral sclerosis
4. Infections like syphilis
5. Leukoencephalopathies (diseases affecting the brain's'white' areas)
6. Brain injuries
7. Multiple system atrophy

Causes of dementia which can be treated include:

1. Hypothyroidism
2. Heavy metal poisoning
3. Certain brain tumors
4. Chronic alcoholism
5. Hiv/aids
6. Vitamin b12 deficiency
7. Medicinal side effects or abnormal drug reactions
8. Normal pressure hydrocephalus
9. Certain cases of encephalitis

Symptoms

Symptoms of dementia include:

1. Memory loss
2. Difficulty finding the right words
3. Difficulty exercising judgments, especially during emergencies
4. Inability to recall particular events or to recognize people and places
5. Depression or other mood disorders, in addition to symptoms like uncontrolled aggression or constant agitation.

Causes and Symptoms of Dementia

What is Parkinson s disease?
Parkinson s disease is a progressive and degenerative disorder of the Central Nervous System that mostly affects older people. It is a chronic disease and the symptoms develop over a period of time. The characteristic symptoms of Parkinson s are rigidity, shaking, bradykinesia (slowness in movement) and shuffled gait. Anxiety and depression also seem to be common in advanced stages of Parkinson s disease. In addition to the motor symptoms, the cognitive function of the brain is also compromised.

Degeneration of the nerve cells in the substantia nigra of the brain results in the reduction in production of dopamine which is a neurotransmitter in the brain. Neurotransmitters relay impulses from one nerve to the other. This is what is mainly responsible for the motor symptoms in Parkinson s. Although, Parkinson s is not a curable disease, it can be controlled and the progress of the disease can be kept in check with certain medications.

What causes Parkinson s disease?
The cause of Parkinson s is mostly idiopathic, i.e. the cause is unknown and is not specific. However, there have been cases which show that it can be attributed to factors such as genetic and environmental factors.
What are the symptoms of Parkinson s?

The symptoms of Parkinson s can be classified as Motor symptoms and Non-motor symptoms:

Motor Symptoms 

Bradykinesia: Slow movement
Tremor of limbs
Rigidity or stiffness of trunk and limbs
Impaired balance and difficulty in coordination or postural instability
Non-motor Symptoms 

Depression
Anxiety and fear
Loss of energy and fatigue
Constipation
Excessive salivation
Weight gain or weight loss
Cognitive problems such as difficulty in remembering, confusion, dementia
Parkinson s disease is not curable, but when detected early, medicines are prescribed to give symptomatic relief. Dopamine substitutes are prescribed to the patient to relieve the motor symptoms.

Parkinson's Disease - Understanding The Motor & Non-motor Symptoms!

With age, most body organs begin to deteriorate in their function. This happens to the brain also, thereby reducing the overall speed of functioning of most organs. While slowing of bodily movement is visible, the internal organs functioning also slows down, which is not that obvious. Memory loss or dementia is one of the main manifestations of this degeneration of the brain.

Alzheimer s is the most common form of dementia, and the associated symptoms includes reduced reasoning abilities and cognitive defects. Though it is seen only in the elderly, not all elderly people will have Alzheimer s. The overall quality of life of the affected person is reduced with difficulty remembering things that were recently learned. It is a progressive disease and as it gets more severe, a full-time caretaker may be required.

Causes: The brain cells are affected by protein masses known as plaques and tangles. These hamper the way communication between the brain cells happens as well as affect nutrition from reaching all parts of the brain. This leads to shrinking of the brain, eventually leading to memory loss and other problems. There is also a strong genetic linkage, as most people with Alzheimer s have the lipoprotein A gene.

Symptoms: Though memory loss is the most common symptom, there are other symptoms:

Being confused about places, people, and times
Inability to find the right words during conversations
Regular objects are misplaced
Becoming irritable, (in someone who was not so previously)
Mood swings
Personality changes
Inability to organise thoughts
Not able to make the right decisions
Repetitive talks and actions
Forgetfulness (not something the person always does)
Difficulty with numbers (again, not something calculations
Difficulty managing everyday tasks and minor problems
Suspicion of others (like immediate family members and friends)
Risk factors: While age is definitely a risk factor, the fact that not all aged people develop Alzheimer s is to be borne in mind. Other risk factors include the history of stroke, high cholesterol, high blood pressure, diabetes, smoking, obesity, and poor lifestyle choices.

Diagnosis: While there is no definitive way to diagnose Alzheimer s, symptoms along with brain scans and neuropsychological function testing are useful ways to confirm the diagnosis.

Treatment: This is aimed at two things reducing the rate of disease progression and treat (or reverse) symptoms if possible.

Cholinesterase inhibitors improve cellular communication in the brain and also manage depression and agitation. Memantine is used to slow the pace of disease progression.
In people with the disease, small changes are useful to help them with the symptoms. These include keeping essential things like keys and wallet in the same place, keep a daily diary to help them remember things, keep pictures of friends and family within visible distance.

Alzheimer's - An Overview!

Don't wait any longer, manage your Neurodegeneration online with a Lybrate doctor today

Consult for Neurodegeneration - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES