One of the common ailments in the elderly people is the Parkinson s. A progressive disorder, when left untreated, results in worsening of the symptoms. Hence, it is essential to understand the treatment options available to manage the condition effectively. You may be suggested surgical therapies if medication is not effective enough to treat the symptoms.

Surgical treatment options can be beneficial for patients who are suffering from symptoms, but they do not help with treating the disease. In the past, surgical methods like Thalamotomy and Pallidotomy were used to destroy brain cells that contributed to the symptoms. While these methods are still used, they are very rare and situational.

Deep Brain Stimulation (DBS), an FDA-approved procedure, has become much more popular as it is much safer and does not involve invasive surgery. Instead of destroying brain cells like traditional methods, DBS involves sending electric pulses to the affected brain cells to reduce the symptoms. It is not a treatment procedure, but a means of bringing down the severity of Parkinson s to allow better and more comfortable treatment.

Deep Brain Simulation   Who are the right candidates?
Deep Brain Simulation is commonly used for Parkinson  s disease, but it is not recommended for everyone. It is a preferred method of treatment for people who have had Parkinson s for at least four years but have complications which include long periods of time where medications do not work, or symptoms return, uncontrolled and involuntary movements or the freezing/stiffness in the body.

Deep Brain Simulation is not recommended for those who have Dementia as it can lead to memory problems. The general rule of thumb that neurosurgeons follow is that Deep Brain Simulation can help with symptoms that do not get better with medication. DBS can help reduce medication requirements for patients as well as reduce the side effects that may occur due to medication.

Disorder specialists and neurosurgeons can conduct tests to determine if DBS is going to be effective for a patient before going ahead with such a procedure. An extensive assessment is necessary to understand the symptoms, the effect of Parkinson's drugs and also brain imaging is done. All of the expected benefits are then evaluated for the patients, and if the procedure can help alleviate the symptoms, DBS is given a green signal by neurosurgeons and patients can undergo the procedure.

How Does Deep Brain Simulation Work?
Deep Brain Simulation is a very complex procedure. Brain cells communicate with the rest of the body through electric signal, and these become irregular and do not work properly when affected by Parkinson's. DBS smoothens the functioning of these brain cells and reduces symptoms through electric pulses through the implantation of a medical device known as neurostimulator which is also referred as brain pacemaker.

But, as with any treatment procedure, DBS has potential risks and side effects, hence discuss with neurosurgeon thoroughly to access the suitability.

Adopting Deep Brain Stimulation For Parkinson's disease

What is Parkinson s disease?
Parkinson s disease is a progressive and degenerative disorder of the Central Nervous System that mostly affects older people. It is a chronic disease and the symptoms develop over a period of time. The characteristic symptoms of Parkinson s are rigidity, shaking, bradykinesia (slowness in movement) and shuffled gait. Anxiety and depression also seem to be common in advanced stages of Parkinson s disease. In addition to the motor symptoms, the cognitive function of the brain is also compromised.

Degeneration of the nerve cells in the substantia nigra of the brain results in the reduction in production of dopamine which is a neurotransmitter in the brain. Neurotransmitters relay impulses from one nerve to the other. This is what is mainly responsible for the motor symptoms in Parkinson s. Although, Parkinson s is not a curable disease, it can be controlled and the progress of the disease can be kept in check with certain medications.

What causes Parkinson s disease?
The cause of Parkinson s is mostly idiopathic, i.e. the cause is unknown and is not specific. However, there have been cases which show that it can be attributed to factors such as genetic and environmental factors.
What are the symptoms of Parkinson s?

The symptoms of Parkinson s can be classified as Motor symptoms and Non-motor symptoms:

Motor Symptoms 

Bradykinesia: Slow movement
Tremor of limbs
Rigidity or stiffness of trunk and limbs
Impaired balance and difficulty in coordination or postural instability
Non-motor Symptoms 

Depression
Anxiety and fear
Loss of energy and fatigue
Constipation
Excessive salivation
Weight gain or weight loss
Cognitive problems such as difficulty in remembering, confusion, dementia
Parkinson s disease is not curable, but when detected early, medicines are prescribed to give symptomatic relief. Dopamine substitutes are prescribed to the patient to relieve the motor symptoms.

Parkinson's Disease - Understanding The Motor & Non-motor Symptoms!

Alzheimer s disease is a neurological, irreversible, progressive brain disorder. It is a chronic neurodegenerative dementia that causes the death of brain cells, causing memory loss and cognitive decline. It affects a person s thinking and behavior. The symptoms develop slowly and get worse as time passes.

Causes:
As it is a kind of dementia, Alzheimer s is caused by the death of brain cells. Over a course of time, brain cells die progressively and at the end, the tissue is left with fewer nerve cells and connections. As a result, the total brain size shrinks. Tiny inclusions called plaques and tangles can be seen in the postmortem. These cannot be seen or tested in a living Alzheimer s affected brain. These plaques are given the name  amyloid plaques  because they are found among the dying cells of the brain when a protein called beta-amyloid builds. The tangles stay in the neurons; they are formed from a protein called tau.

There are several reasons behind all this, some of which are listed below-

Anti-anxiety medications
Hitting on the head too many times
Regularly sleep-deprived
Loneliness
Diabetes in the brain
Old age
Genetic line
Down s syndrome
Cardiovascular diseases
Symptoms:
Alzheimer s disease damages the brain, so the clinical signs and symptoms begin to show very early. The symptoms are-

Memory loss
Agitation and mood swings
Poor judgment
The trouble with money calculations
Difficulty doing familiar tasks
Trouble in planning or solving a problem
Confusion with time and place
Difficulty in communicating
Loss of motivation
Inappropriate behavior
Aggressive personality
Childlike behavior
Preventing Alzheimer s disease:
Alzheimer s disease ultimately results in death. Even if there are treatments, they cannot fully cure it. So it s better to try to prevent it before it happens. Ways to prevent Alzheimer s disease are-

Eating more fruits and vegetables.
Eating berries every day.
Increasing omega-3 fatty acids.
Taking folic acid supplements.
Drinking grape juice or red wine with evening meal.
Doing the Mediterranean style diet.
Controlling the blood pressure.
Having strong social support.
Treatment of Alzheimer s disease:

Treatment of Alzheimer s disease is a long time process.
First of all, doctors perform a physical exam to check the overall neurological health. By this, they check muscle strength, reflexes, walking ability, sense of sight and hearing, coordination and balance.
Then comes the blood test to find the cause of confusion and memory loss by checking the thyroid disorder and vitamin deficiency.
Then they perform the neuropsychological test and check the mental status.
Then there are other tests, like MRI, CT, and PET.
After all this, drugs are given and a safe and supportive environment is created with proper exercise and nutrition.
Alzheimer s disease is undoubtedly the worst kind of disease. Hence, it is highly recommended to contact a doctor as soon as any symptom is noticed.

All About Alzheimer's Disease!

The skin is an elastic organ (yes, it is an organ!), but only to a certain extent. It has a limit to which it can accommodate the underlying tissues. With the increase in bulk, for example, puberty, pregnancy, muscle mass building or surgical implants, the skin is made to stretch beyond its limits. What happens is this stretch causes the skin to stretch too, and these stretch marks or striae become an unpleasant thing that needs to be hidden. 

Dressing needs to be changed so that they are not showing. Dermatologists see a big demand for getting rid of these marks too. There have been conventional, time-tested methods which help in getting rid of these. However, with newer advancements in dermatology, the platelet rich plasma is being widely used for getting rid of these stretch marks.

Why stretch marks? 

In any of the scenarios above, the stretch marks appear because there is a lack of underlying supportive tissue when it is stretched out. There is a lack of collagen and connective tissue, causing stretch marks. These are most evident in fat collecting areas like breasts, abdomen, thighs, upper arms, etc.

What is platelet-rich plasma or PRP? 

The blood is composed of a liquid portion known as plasma, which contains three main types of cells i.e. white blood cells, red blood cells, and platelets. The white blood cells are the ones responsible for fighting infections. The red cells give blood its color and also are responsible for carrying nutrients to the various organs. The platelets are tiny fragments of cells which help in blood clotting. Platelets are also rich in what are called totipotent cells, which can grow into any type of cells. When the body is affected, due to injury, infection, trauma, etc., these get concentrated in the affected area and are produced in large numbers to help in the recovery of the particular affected area.

Technique: 

The area to be treated is isolated and prepared. Blood is centrifuged to remove other cells and obtain platelet rich plasma. This RPR is injected into the underlying layers of the skin. This induces the release of growth factors into the connective tissue space. Collagen is produced over a period of time, which causes the skin to become taut and lose the stretch marks. The injection can be repeated if required on the topmost layer. It can also be mixed with thrombin to form a gel, which is then used similarly. Using it both in the underlying and superficial layers helps in completely getting rid of the marks.

Studies have shown a reduction in both the depth and size of the stretch marks and some might require two to three repeat injections.


Stretch Marks - How PRP Therapy Can Help You?

Neurology is the branch of science and medicine dealing with the central and peripheral nervous system. The nervous system is made of the brain and spinal cord. The disorders, illness or injuries of the nervous system can become problematic for people suffering from them. One of the worst diseases of the nervous system is Parkinson s disease.

It is a progressive disorder affecting the central nervous system that leads to slowing down of movement and slurring of speech over a period of time. It is a condition where the nerve cells in the brain producing dopamine (a neurotransmitter) are affected.

Some of the early signs of Parkinson s include:

Tremor: If you have noticed a slight shaking of your hands or limbs, then Parkinson s might be the cause. The trembling can range from mild to severe as the disease progresses. The back-and-forth rubbing of your thumb and forefinger is known as pill-rolling tremor. One of the most prominent signs is your hand shaking even when it is rested.
Bradykinesia (slow movement): As the disease progresses, you may find it difficult to move your hands or legs or going from one place to another. Even making the smallest movement will require an increased effort on your part.
Rigid Muscles: The muscles in your body can become stiff causing you pain and making it difficult to perform physical activities.
Masked Face: Your face may experience spasms or become stiff periodically. It can also lead to complete paralysis on one side of the face.
Stooping or improper balance: Having Parkinson s disease can make your body posture imbalanced resulting in stooping or hunching over.
Decreased Automatic Movements: You may experience difficulty in smiling, blinking or swinging your arms while walking.
Alteration in voice or speaking: Your voice can become soft or you may slur while talking. You can also experience a monotonous voice.
Writing may become small: You can experience changes in your handwriting as it becomes small and crowded.
Loss of Smell: The smell of food sitting right in front of you may not register in your olfactory resulting in loss of appetite.
Constipation: Having Parkinson s disease can lead to patients experiencing irritable bowel syndrome.
Have Trouble Sleeping: It might be difficult to fall asleep for people suffering from Parkinson s. Also, there are sudden movements during the sleeping process.
Dizziness: People suffering from Parkinson s may faint from time to time.
These were some of the symptoms and signs by which you can tell whether a person has Parkinson s or not. However, as of now it is not curable and can only be treated with medicines. But, early detection can definitely help in preventing it from affecting the whole body.

Parkinson's Disease - Are You Aware Of These Signs?

One of the worst neurological disorders to have is dementia. It is a general term used to describe cognitive decline of the brain. It s not specific disease but denotes several brain disorders and mental illnesses. A person suffering from dementia can have severe impairment in judgment, loss of memory and thinking. Dementia is a very difficult disease not only for the patient but also for their families and caregivers. 

Some facts about dementia are as follows:

It s not a mental disorder occurring in old age but it does degenerates with age.
An estimation of 47.5 million people worldwide suffers from dementia and 60% of these people live in low and middle-income countries and according to WHO this figure is likely to increase.
Every 4 seconds a new case of dementia is reported
Dementia is a collective term to describe the many types of in people, such as 

Alzheimer s Disease: It is one of the most common type of dementia accounting for 60-80% of dementia case. People suffering from Alzheimer s have fewer nerve cells and the size of the brain shrinks.
Vascular Dementia: Another most common form of dementia occurring after a stroke.
Lewy Body Dementia: It is neurodegenerative condition that involves a protein called alpha-synuclein which changes the brain. Symptoms may be similar to Parkinson s disease.
Symptoms of dementia can range from mild to moderate to severe that includes:

Memory Loss
Disorientation meaning inability to focus or pay attention
Changes in visual perception
Impairment in reasoning and judgment
Dementia can be caused by damage to brain cells or progressive brain cell death. As a result communication between brain cells become difficult. Other symptoms include:

Stroke
Brain Tumor
Head Injury
Prion Disease
HIV Infection
Reversible Factors

There are no definite tests for dementia. Doctors and neurologists have to medical history, blood tests and CT scans to find out whether a person has dementia or not. However, the most potent evaluation comes from a set of questions that are asked to a patient suspected of having dementia. The ability to answer those questions correctly is one of the best diagnoses for dementia.
There is no specific treatment for dementia as it is not a curable disease and degenerates with time. However, medicines or drugs given for Alzheimer s can be given to people suffering from dementia.
Although results vary depending upon a person s lifestyle s and habits, doctors suggest eating healthy, exercising regularly, and stopping smoking and drinking may prevent some types of dementia.
The best treatment for dementia is to treat the person with care and love so that they don t feel neglected.
Dementia is often associated with old age but that is not always true. It is important to gain knowledge and educate others also.

Dementia - Quick Facts You Must Know About It!

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