Parkinson s disease is a disorder involving the nervous system. It can start with a mere tremor of one hand and advances to slow movement and stiffness. The face might show little no symptoms in the beginning but the speech might become slurred. With every passing day, the condition worsens. This condition has no permanent cure but the symptoms can be improved with proper medication.

What are the symptoms?
Some unmistakable symptoms include the following:

A sudden shaking of the limb. A sudden tremor of the hand is a very common symptom of this disease.
Stiffness of the muscles that can limit the range of motion and sharp pain.
The posture of the body might get compromised. Often balancing problems are witnessed among many patients.
There could be problems with speech leading to soft, slurry or quick speech. The speech in some cases can become monotonous devoid of inflexions.
Parkinson s disease can lead to slow movement and makes performing of simple tasks difficult.
Patients often find writing very difficult
What are the possible causes of Parkinson s disease?

Specific genetic mutation can lead to Parkinson s disease in folks who have a family history of Parkinson s disease. Certain variations of the gene increase the risk of this disease
Exposure to certain environmental factors or certain toxins can trigger Parkinson s disease in an individual.
Certain cells in the brain known as Lewy bodies can trigger Parkinson s disease.
A certain kind of protein cells within the brain known as alpha-synuclein can trigger the Parkinson s disease in an individual
What are the risk factors?

Heredity: Having an immediate family member or close relative suffering from Parkinson s disease can increase the risk of getting this disease in an individual
Age: Although not a prime risk factor, but an individual over the age of over 60 have an increased risk of getting this disease
Toxins: Exposure to pesticide or certain herbicide increase the risk of Parkinson s
Sex: Men are more likely to get Parkinson s disease than women
What is the medication for Parkinson s disease?

Carbidopa-levodopa: This is a natural chemical that gets passed to the brain and is converted to dopamine by the body. The benefits of this medication might reduce with increased symptoms.
Carbidopa-levodopa infusion: A popular drug in this category is known as the Duopa. It is administered directly into the small intestine in the form of gel through a feeding tube.
MAO-B inhibitors: Drugs from this group include rasagiline and selegiline. This is powerful medicine. Many patient experiences hallucination during the initial days of consuming these drugs.
Anticholinergics: This medication is mainly used to counter tremors of the limbs in the early stage of Parkinson s disease.

Parkinson's Disease - Know The Risks Involved!

Alzheimer's disease is a neurodegenerative disorder that causes a degradation and eventually death of the brain cells. People with Alzheimer's disease suffer from a memory loss. There is also a progressive decline in the cognitive capacity of the brain.Today, Alzheimer's disease and dementia have become almost synonymous with old age. It is a heartbreaking experience to see aged people with Alzheimer's disease. They have little or no memory of the present time, of their loved people or the things around them. 

The Alzheimer's disease starts off as a mild condition and then gradually progresses through stages. In this article, we will discuss the different stages associated with Alzheimer's disease.

The first stage: This stage shows no significant changes in the affected person. Thus, without any diagnostic tests (such as a PET scan), it will be difficult to detect the condition in the initial stage.
The second stage: This stage brings about some changes in the person. The person might misplace things or may even forget words (something that is often brushed aside as a small problem). However, this seldom interferes with their daily activities. Like the first stage, this stage, in most cases, goes unnoticed.
The third stage: This is the stage that brings about visible changes in the person concerned such as
The person experiences difficulties in trying to organize things.
They forget things they have read, or heard just a few seconds back.
In some cases, the person may not be able to recollect a person's name they have just met.
Some people may end up repeating the same question over and over again.
The fourth stage: This stage marks a further decline in the mental health. The person gets forgetful about himself or herself. They also start mixing up with the dates and months or makes major goof up while cooking (misses out on ingredients).
The fifth stage: The mental deterioration reaches a step further. The person slowly starts forgetting about the present, such as their address, the time of the day, their profession and even phone numbers.
The sixth stage: The problem is getting worse. Hallucination is slowly setting in. The person is starting to forget people and their faces, mixing one identity with another.
The seventh stage: The final and unfortunately, the worst stage. The person stops talking to people, eating, or even walking. They stay confined to their world, oblivious of their immediate surrounding.
Dealing with an Alzheimer patient

In addition to the treatment and medication, a person with Alzheimer's disease needs the love, care, and support of their close and dear ones. Isolating them will only worsen the situation.
It may not be easy to deal with an Alzheimer's patient as the disease progresses, but do not be rude to them. Give them the confidence.
Always keep a paper containing their name, address and emergency contact number in their wallet.
People after the age of 50 should undergo regular health check ups.

Alzheimer's - How The Disease Progresses?

Alzheimer's disease is a dynamic disease that causes loss of memory and other vital mental functions. To start with, someone with Alzheimer's disease may witness light confusion in the beginning and trouble recalling. In the long run, individuals with the disease may even overlook important individuals in their lives and experience emotional identity changes.

Dementia: Alzheimer s disease is the most widely recognised reason for dementia   a gathering of brain issues that causes the loss of intellectual and social abilities. In Alzheimer's disease, the brain cells deteriorate and die, bringing on an enduring decrease in memory and mental capacity.
Brain Cells: Despite the fact that the reasons for Alzheimer's is not yet completely comprehended, its impact on the brain is clear. Alzheimer's disease harms the brain cells. A mind influenced by Alzheimer's has fewer cells and fewer associations among surviving cells than a solid mind.
Brain Shrinkage: As more brain cells start to die, Alzheimer's prompts critical brain shrinkage. At the point when specialists inspect Alzheimer's brain tissue under the magnifying instrument, they see two sorts of irregularities that are considered to cause Alzheimer s. These are:
Plaque: These clusters of a protein called beta-amyloid may harm and crush brain cells in a few ways, meddling with cell-to-cell functioning. In spite of the fact that a definitive reason for brain cell passing in Alzheimer's is not known, the accumulation of beta-amyloid on the outside of brain cells is a prime reason.
Tangles: Brain cells rely upon an inner support and transport framework to carry the supplements and other fundamental materials through their long extensions. This framework requires the typical structure and working of a protein called tau. In Alzheimer's, strings of tau protein turn into strange tangles inside the brain cells. This may also cause the decrease of brain cells. 
Here are some more causes that can lead to this disease:

Age: Age is a most critical cause in the development of Alzheimer's disease. The probability of building up the condition increases after you reach sixty-five years of age.
Family history: The qualities you acquire from your parents can add to your danger of building up Alzheimer's infection. This may also contribute to the environmental factors which can cause this condition. In some families, a single gene creates Alzheimer s disease and the dangers of the condition being passed on are much higher.
Head injuries: Individuals who have had serious head damage have been observed to be at higher risk of building up Alzheimer's disease.
Cardiovascular diseases: Research demonstrates that few lifestyle components and conditions connected with cardiovascular disease can build the danger of Alzheimer's disease. These include smoking, obesity, diabetes, hypertension and high cholesterol.


Alzheimer's Disease - Reasons That Can Lead To It!

The skin is an elastic organ (yes, it is an organ!), but only to a certain extent. It has a limit to which it can accommodate the underlying tissues. With the increase in bulk, for example, puberty, pregnancy, muscle mass building or surgical implants, the skin is made to stretch beyond its limits. What happens is this stretch causes the skin to stretch too, and these stretch marks or striae become an unpleasant thing that needs to be hidden. 

Dressing needs to be changed so that they are not showing. Dermatologists see a big demand for getting rid of these marks too. There have been conventional, time-tested methods which help in getting rid of these. However, with newer advancements in dermatology, the platelet rich plasma is being widely used for getting rid of these stretch marks.

Why stretch marks? 

In any of the scenarios above, the stretch marks appear because there is a lack of underlying supportive tissue when it is stretched out. There is a lack of collagen and connective tissue, causing stretch marks. These are most evident in fat collecting areas like breasts, abdomen, thighs, upper arms, etc.

What is platelet-rich plasma or PRP? 

The blood is composed of a liquid portion known as plasma, which contains three main types of cells i.e. white blood cells, red blood cells, and platelets. The white blood cells are the ones responsible for fighting infections. The red cells give blood its color and also are responsible for carrying nutrients to the various organs. The platelets are tiny fragments of cells which help in blood clotting. Platelets are also rich in what are called totipotent cells, which can grow into any type of cells. When the body is affected, due to injury, infection, trauma, etc., these get concentrated in the affected area and are produced in large numbers to help in the recovery of the particular affected area.

Technique: 

The area to be treated is isolated and prepared. Blood is centrifuged to remove other cells and obtain platelet rich plasma. This RPR is injected into the underlying layers of the skin. This induces the release of growth factors into the connective tissue space. Collagen is produced over a period of time, which causes the skin to become taut and lose the stretch marks. The injection can be repeated if required on the topmost layer. It can also be mixed with thrombin to form a gel, which is then used similarly. Using it both in the underlying and superficial layers helps in completely getting rid of the marks.

Studies have shown a reduction in both the depth and size of the stretch marks and some might require two to three repeat injections.


Stretch Marks - How PRP Therapy Can Help You?

Neurology is the branch of science and medicine dealing with the central and peripheral nervous system. The nervous system is made of the brain and spinal cord. The disorders, illness or injuries of the nervous system can become problematic for people suffering from them. One of the worst diseases of the nervous system is Parkinson s disease.

It is a progressive disorder affecting the central nervous system that leads to slowing down of movement and slurring of speech over a period of time. It is a condition where the nerve cells in the brain producing dopamine (a neurotransmitter) are affected.

Some of the early signs of Parkinson s include:

Tremor: If you have noticed a slight shaking of your hands or limbs, then Parkinson s might be the cause. The trembling can range from mild to severe as the disease progresses. The back-and-forth rubbing of your thumb and forefinger is known as pill-rolling tremor. One of the most prominent signs is your hand shaking even when it is rested.
Bradykinesia (slow movement): As the disease progresses, you may find it difficult to move your hands or legs or going from one place to another. Even making the smallest movement will require an increased effort on your part.
Rigid Muscles: The muscles in your body can become stiff causing you pain and making it difficult to perform physical activities.
Masked Face: Your face may experience spasms or become stiff periodically. It can also lead to complete paralysis on one side of the face.
Stooping or improper balance: Having Parkinson s disease can make your body posture imbalanced resulting in stooping or hunching over.
Decreased Automatic Movements: You may experience difficulty in smiling, blinking or swinging your arms while walking.
Alteration in voice or speaking: Your voice can become soft or you may slur while talking. You can also experience a monotonous voice.
Writing may become small: You can experience changes in your handwriting as it becomes small and crowded.
Loss of Smell: The smell of food sitting right in front of you may not register in your olfactory resulting in loss of appetite.
Constipation: Having Parkinson s disease can lead to patients experiencing irritable bowel syndrome.
Have Trouble Sleeping: It might be difficult to fall asleep for people suffering from Parkinson s. Also, there are sudden movements during the sleeping process.
Dizziness: People suffering from Parkinson s may faint from time to time.
These were some of the symptoms and signs by which you can tell whether a person has Parkinson s or not. However, as of now it is not curable and can only be treated with medicines. But, early detection can definitely help in preventing it from affecting the whole body.

Parkinson's Disease - Are You Aware Of These Signs?

Alzheimer s disease is a neurological, irreversible, progressive brain disorder. It is a chronic neurodegenerative dementia that causes the death of brain cells, causing memory loss and cognitive decline. It affects a person s thinking and behavior. The symptoms develop slowly and get worse as time passes.

Causes:
As it is a kind of dementia, Alzheimer s is caused by the death of brain cells. Over a course of time, brain cells die progressively and at the end, the tissue is left with fewer nerve cells and connections. As a result, the total brain size shrinks. Tiny inclusions called plaques and tangles can be seen in the postmortem. These cannot be seen or tested in a living Alzheimer s affected brain. These plaques are given the name  amyloid plaques  because they are found among the dying cells of the brain when a protein called beta-amyloid builds. The tangles stay in the neurons; they are formed from a protein called tau.

There are several reasons behind all this, some of which are listed below-

Anti-anxiety medications
Hitting on the head too many times
Regularly sleep-deprived
Loneliness
Diabetes in the brain
Old age
Genetic line
Down s syndrome
Cardiovascular diseases
Symptoms:
Alzheimer s disease damages the brain, so the clinical signs and symptoms begin to show very early. The symptoms are-

Memory loss
Agitation and mood swings
Poor judgment
The trouble with money calculations
Difficulty doing familiar tasks
Trouble in planning or solving a problem
Confusion with time and place
Difficulty in communicating
Loss of motivation
Inappropriate behavior
Aggressive personality
Childlike behavior
Preventing Alzheimer s disease:
Alzheimer s disease ultimately results in death. Even if there are treatments, they cannot fully cure it. So it s better to try to prevent it before it happens. Ways to prevent Alzheimer s disease are-

Eating more fruits and vegetables.
Eating berries every day.
Increasing omega-3 fatty acids.
Taking folic acid supplements.
Drinking grape juice or red wine with evening meal.
Doing the Mediterranean style diet.
Controlling the blood pressure.
Having strong social support.
Treatment of Alzheimer s disease:

Treatment of Alzheimer s disease is a long time process.
First of all, doctors perform a physical exam to check the overall neurological health. By this, they check muscle strength, reflexes, walking ability, sense of sight and hearing, coordination and balance.
Then comes the blood test to find the cause of confusion and memory loss by checking the thyroid disorder and vitamin deficiency.
Then they perform the neuropsychological test and check the mental status.
Then there are other tests, like MRI, CT, and PET.
After all this, drugs are given and a safe and supportive environment is created with proper exercise and nutrition.
Alzheimer s disease is undoubtedly the worst kind of disease. Hence, it is highly recommended to contact a doctor as soon as any symptom is noticed.

All About Alzheimer's Disease!

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