Causes and symptoms of acute tubular necrosis

Damage or destruction to tube-like structures known as tubules in the kidneys can bring about the development of acute tubular necrosis (ATN) and subsequently, acute kidney failure.

What causes acute tubular necrosis (ATN)?

A lack of supply of oxygen to the cells in the kidney is the most common cause of this condition. The reason as to why oxygen may not reach the cells and tissues of this organ could be restriction or blockage of the pathways. When this happens, the kidneys get damaged. Dehydration is the most important cause of ATN which may be because of loose motions, vomitings, heat stroke etc.

Health conditions such as diabetes, heart attack, and stroke can bring about a decrease in blood flow to the organs resulting in ATN and death of cells. Similarly, the presence of toxic substances in the blood can also lead to tubules damage and change the way the cells function in the tubules.

Other causes that may lead you to develop ATN may be medications, radiology dyes, anesthetics and chemicals that cause your body to react adversely.

In addition to these causes, a number of factors can put you at risk of ATN and there are:

- An injury to the body, more specifically your kidneys can cause clotting of the blood vessels
- An adverse response to blood transfusion
- Instances of septic shock can slow down blood flow to the organs
- A major surgery that can interrupt blood supply to the organs

What are the symptoms of the condition?

The symptoms associated with the condition can vary depending on the severity of the problem.

You may experience:

- Troubles in waking up
- Drowsy feeling even during daytime
- Feelings of lethargy
- Feelings of excessive thirstiness
- Problems with urination
- Fluid retention problems
- Instances of confusion
- Feelings of nausea



Can Acute Tubular Necrosis Cause Kidney Failure?

One single kidney in place of two is a scenario which is often termed as solitary kidney.

Who has a solitary kidney?

Their body functions normally and are generally not unhealthy. This is also known as renal agenesis.
In some cases, people are born with two kidneys with just one of them healthy and fully functional. The other one does not function fully or partially. This condition is known as kidney dysplasia.
A person who had to undergo a kidney removal surgery (nephrectomy); such a surgery is conducted when a person has an infected kidney or diseased, malfunctioning/cancerous growths on the kidney.
A person who has donated a kidney to someone who required kidney transplantation.
What potential health risks does a person with a solitary kidney have?

Normally, a person born with a single kidney does not have any such potential health risks. They are generally healthy and lead normal lives.
Later in life, there may or may not be slight loss or degradation in the functioning of the kidney.
The life span of a person with a single kidney is normal. There is no apparent effect on the mortality rates.
What kind of special diet must a person with a single kidney follow?

There is no need of any such special diet for a person with a single kidney.
Normal healthy balanced diet with all the essential nutrients should suffice.
You must be careful about your animal protein intake and calcium supplements.
Drink sufficient quantity of water to remain hydrated all day and prevent the urine from turning acidic.
Controlled consumption of alcohol and caffeine is a must. It is also important to reduce the consumption of aerated drinks.
Exercises and Physical activities for a person with a single kidney:

A person with a solitary kidney can function like any other normal individual.
You may also participate in sports. However, you must take enough precaution to prevent injuries to your kidney. Proper padding and protection around your lower abdominal region and back is of utmost necessity.
You can hit the gym, run a marathon and nothing is impossible for you.

Living With Solitary Kidney - Things You Need to Know!

A lot of bad things can and do happen when the kidneys fail.  The kidneys are vital for proper bodily functioning because they filter liquid and solid waste products out of the blood and allow vital chemicals (which the body needs for functioning) to flow into the body through the bloodstream.  People can become very sick when the kidneys either fail to perform these functions or fail to perform them properly.  Many people will get chronic kidney disease, therefore, they need to know what the causes and symptoms are in order to treat, and even prevent these diseases from occurring.

People who suddenly experience the following symptoms should see a nephrologist as soon as possible for a medical examination:  blood or protein in the urine, kidney stones, acute kidney injury, kidney infections, and/or pain, and Hepatitis C and kidney disease.  

Blood in the urine can be a sign of kidney problems which can lead to kidney disease.  Additionally, people who urinate frothy or bubbly urine, or have swelling in the hands, face, and feet should see a doctor because this is a sign of protein in the urine.  Protein in the urine can be detected by a urine test.  Kidney stones can be very painful and are problematic.  They are caused by mineral buildup in the kidneys.  Men and white people tend to get kidney stones more, and they can cause blood in the urine, painful urination, sharp lower abdominal or back pain, and nausea and vomiting.

Acute kidney injury occurs when the kidneys stop functioning altogether in a short period of time.  Because this disease can be deadly, those with this disease should get immediate medical help.  Usually, the very sick patients in hospitals get this disease, but it can also be caused by certain medicines, injury, or infections.  This type of kidney disease is easily reversible.  

Symptoms include

Not passing enough urine when urinating
Leg, ankle, or feet swelling
Fatigue
Breathing problems
Confusion
Nausea, and chest pressure or pain. 
Kidney infections tend to be caused by bacteria that have spread from the urinary tract.  Women, because of their anatomy, tend to get kidney infections more than men. 

Symptoms include:

Fever
Vomiting
Back, side or groin pain
Chills
Nausea
Frequent urination
Frequent urges to urinate
Painful or burning urination
Pus or blood in the urine
Cloudy or foul-smelling urine
Kidney pain in the lower back or sides can signify more serious kidney problems.  They can be caused by urinary tract infections, polycystic kidney disease, kidney infections, blood clots, and/or bleeding in the kidneys.  
Hepatitis C is a disease that attacks the liver and can cause kidney disease.  

Symptoms include

Loss of appetite
Nausea
Fever
Fatigue
Vomiting
Dark colored urine
Grey colored stool
Joint pain
Yellow skin and eyes
While kidney diseases are at best unpleasant, and at worst, life-threatening, they can be avoided by drinking lots of water, eating a healthy low salt diet, and watching for any changes in health and urine over time.



What Happens When Kidneys Fail & Signs That Indicate It

Those two, small bean-shaped organs are indeed essential for a perfectly healthy life. To check if a person is dead or living, medical practitioners need to confirm response from three organs of the human body heart, brain and kidneys. Kidneys absorb impurities from the blood, thus, purifying it and lead to the production of urine. Urine is necessary to rid your system of body wastes. Kidneys play a key role in maintaining hormone balance. The presence of any factor that could impede free functioning of this organ should be diagnosed, treated and eliminated at the earliest possible. Kidney diseases and subsequent kidney failure see no age bar. It affects both young and old people. In case of younger folks, the symptoms take years to surface and thus the chances of a fatal outcome are even higher.

Causes of kidney failure at a tender age:

    Chain smoking is a trigger: Smokers suffer from a higher risk of kidney failure. Smoking is a bad habit that has engulfed almost ninety percent of young adults. Irrespective of awareness programs and warning messages, there are millions who smoke nonchalantly. Smoking is known to impair kidney function which again can have frightening implications.
    High blood pressure levels must be controlled: Since stress is a common phenomenon among most individuals high blood pressure is also prevalent among a majority of these individuals. Younger people suffer from high blood pressure due to workplace politics and familial tensions. High blood pressure should not be taken lightly. Exercising and regular medications should be opted for in order to counter the threat of kidney failure at a young age.
    If you are obese, you are stepping closer to the threat: If not optimal; being close to the optimal body weight is very necessary to keep health disorders in check. If you are obese, you are not safe; one must make efforts to lose weight or else face the alarming situation when his or her kidneys fail to function properly.
    Consumption of junk food can cause complications: Junk food is fatty. One must keep away from high-protein and high-fat diet. Food items rich in protein and fats can push you towards chronic kidney diseases.
    Genetics may discern the health of your kidneys: The incidence of kidney failure in your family history can make you prone to a similar condition. Extra care should be taken to avoid any such possibility. Regular health check-ups should be undertaken.

Why You May be at the Risk of Kidney Failure at an Early Age

A kidney transplant is a surgical procedure that patients of kidney disease go through in order to replace a non functioning kidney with a live one that is healthy and functions well. Other methods to treat this disease also include dialysis, which basically is an artificial way of doing what our kidneys are designed to do. When dialysis does not work, many doctors recommend a kidney transplant. A replacement or donated kidney can come from a living donor or a non-living donor. This new kidney will mostly work towards keeping the blood clean, which is a function that stops when the old and diseased kidneys fail.
 
So, here's a list of five essential facts that you need to keep in mind if you are looking at a kidney transplant:

1. Donors: While there are living and non-living donors, the doctor will have to ensure that your donor is someone who has no medical history of complications, kidney disease or any other medical condition like diabetes or hypertension. Also, the donor would have to have two proper functioning kidneys. Further, one of the most important factors is the blood group. The blood group of the donor and the patient must match for the transplant to be possible.

2. Procedure: During the surgery, the patient will be under general anesthesia. The surgeon will make an incision in the lower abdomen area and the blood vessels of the new kidney will be connected surgically with the vein and iliac artery of the patient. Thereafter, any excess fluid will be drained before wrapping up the surgery.

3. Rejection: The patient's body may also reject the kidney. The immune system of the patient may mistake the new kidney as an attacking body and its natural defenses may work against it, which will lead to complications. For this, doctors usually prescribe immunosuppressant medicines that will help in preventing such an eventuality. 

4. Longevity: While a living donor's kidney may last longer, a non-living donor's kidney will not enjoy such a long life. In such cases, a second transplant can be conducted.

5. Diet: After the transplant, the patient will be required to go through a number of measures like coughing to show that the lungs are clear, as well as administration of fluids and some amount of examination and dialysis. Also, the patient will have to have a special diet that includes raw fruits and vegetables, and plenty of non-fat dairy ingredients.

A kidney transplant is a major operation that can change your lifestyle in the long run. 

5 Things You Should Know About Kidney Transplant

Acute kidney failure is the kidney's inability to filter waste from the blood. As soon as the kidney loses the filtering ability, a humungous amount of body waste gets accumulated in the kidney and the chemical makeup of the body goes out of balance. Kidney or renal failure can progress tremendously from hours to days. This is a condition that is mostly witnessed in critical patients who are already hospitalized. This condition can prove to be fatal but can be reversed with treatment and medication. Here is a list of things one should do whilst suffer from kidney failure:

Lifestyle and dietary adjustments
During the phase of recovery, the medical team might assist a patient to go a special diet and limit the activity of the kidney so that they get the required time to heal. A nephrologist often routes this cases to a dietician or carefully analyses the present diet to lock up on the diet required for a speedy recovery:
Lower amount of potassium in food: Food with low potassium content is often recommended by the doctor. It ensures that kidney does not stress itself. Foods to avoid include spinach, bananas, oranges, tomato and potato. Some of the foods that need to be included in the diet are cabbage, strawberries, apples and grapes. Furthermore, food must be consumed in small quantities but in multiple servings.
Limit the amount of phosphorus in food: Phosphorus is found in abundant quantities in food items such as peanut butter, milk, dried beans, cheese and nuts. Along with skin itchiness, phosphorus can weaken the bone as well. A dietitian might share special instructions on how to cut down the amount of phosphorus and the substitute food to counter the effect of the above-mentioned ones.
Avoid salty products: It is extremely necessary to cut down food items that contain an excess amount of salt in it. Food products such as the canned soup, frozen dinner, and fast food are the major culprits in worsening the condition. Processed meats and cheese are equally bad.

Preventive measures to avoid kidney failure:

OTC pain medications: It is necessary to check the label of over the counter pain medications. Consumption of too many OTC medications can result in kidney failure. A pre-existing kidney condition can further aggravate this condition.
A healthy lifestyle: A sensible lifestyle with simple diet can do wonders for a kidney to be healthy in the long-term. Some of the other things to keep in mind include doing regular exercise, refrain from alcohol or drug abuse and remain active throughout the day.
Consult a doctor: Even a hint of a kidney problem should be discussed with a doctor to ensure that even the smallest of problems can be addressed at the earliest. 

Acute Kidney Failure - What Should You Do In Such A Case?

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