The liver has a significant role to play in metabolism and digestion. The failure of a liver can lead to significant health issues. There are some causes for liver failure, which cannot be treated with medications. In these people, a transplant, which is replacing the diseased or injured liver with another liver, is the only definitive treatment option.

Some conditions which can require a liver transplant are:

Severe cirrhosis with a life expectancy of less than a year
Severe liver failure
Non-alcoholic steatohepatitis (NASH)
Liver cancer
Chronic hepatitis C
Biliary atresia in children
Types of transplant:

Living donor transplant: In some patients, partial liver can be removed from a close family member and transplanted into the affected individual. The liver is known for its regeneration ability, and over time, will grow in the recipient.
Cadaveric transplant: Immediately after death, a liver can be removed and transplanted.
While the concept of a transplant sounds quite convincing and appealing for those with a severe liver disease, it is also important to note that not all would qualify for a liver transplant. The conditions which would disqualify a recipient are discussed below:

Significant heart disease: Those with severe coronary artery disease, valvular disease, cardiomyopathy, aortic stenosis, and cardiomyopathy are not candidates for a liver transplant.
Severe lung disease: Those with poor lung perfusion do not qualify for a liver transplant.
Advanced age: Greater the age, lesser the survival rates. So, people aged more than 70 are usually not considered for a transplant.
Obesity: A person with a BMI of more than 35 is often not a good candidate for a transplant. The overall health should be managed in these people.
Malnutrition: On the other extreme, severely malnourished individuals are also not considered for a transplant.
HIV infection: A person who is HIV-infected does not qualify for a liver transplant.
Substance abuse: Anyone who is actively abusing alcohol and/or substances is definitely removed from the list for a transplant.
Metastasis: If a patient is looking for a liver transplant due to hepatic cancer, it is essential that the cancer is contained. If it has spread to various parts, then containing it would be difficult, and a transplant may not succeed.
Multisystem organ failure: Other than heart and lungs, even people with poor renal function are not ideal candidates for a liver transplant.
A detailed liver recipient evaluation assessing the severity of liver disease, chances of survival, and overall health are done before a person is listed for liver transplant. This evaluation ensures a better success rate with the transplant.

Common Surgical Complications That One Should Be Prepared For?

Obesity can shorten your lifespan by decades and also limit and reduce the quality of your life. Obesity cannot always be controlled by dieting and exercise and thus more complicated means such as bariatric surgery has to be employed.

Types of bariatric surgery
Most bariatric surgeries either limit your ability to consume food and thus make you feel fuller quickly or limit the absorption of nutrients from the food you eat. Certain surgeries use a combination of the two in varying degrees. Mentioned below are the most commonly employed forms of bariatric surgery  

Gastric Balloon   This is a form of surgery wherein a specially made balloon is inserted into the stomach. In certain cases even two balloons are inserted into the stomach to reduce the room left for food. This causes you to have less food resulting in weight loss over a period of time.
Gastric Sleeve   This is a form of surgery wherein a major portion of the stomach is removed through the procedure. Also known as Vertical Sleeve Gastrectomy, the surgeon creates a pouch within the stomach which essentially becomes a connecting tube between the esophagus and the large intestine. The reduced stomach size causes fewer hunger related enzymes and hormones to be secreted, causing less hunger and also reducing your food intake capability. This results in weight loss over a period of time.
Gastric Bypass   Gastric bypass uses the combination of two techniques, lesser absorption of minerals as well as reduced intake capacity. In this method, a part of the stomach is rearranged akin to the gastric sleeve. However the leftover portion of the stomach is not removed as it can continue to secrete stomach acids. Because of the reduced size of the stomach, you would eat less and if you happen to over eat, it would cause dumping syndrome (quick and repeated bowel evacuation) which would deter you from eating more.
Lap band surgery   This is one form of surgery where the stomach is not reduced or cut but rather limited by a band that is put around it. This band constricts the stomach and causes the upper part to become smaller. Hence you would feel fuller from eating less, thus resulting in weight loss.
V-bloc therapy   This is a very modern approach to bariatric procedures which works in a very similar way to a pacemaker. A device is placed just under your skin and two leads or wires are connected to the vagal nerve. This nerve is responsible for sending the hunger signals to the brain from the stomach. This device acts as a block to the nerve signals and thus ensures you eat less.
Duodenal switch   This surgery is also known as a Biliopancreatic Diversion wherein the surgeons cut out the part of the stomach similar to a gastric sleeve surgery but also make adjustments to the pancreatic chain and the small intestine to reduce the absorption of minerals.

6 Types Of Bariatric Surgery You Can Think of!

Renal Tubular Acidosis is a medical condition. When the kidney is unable to acidify urine, it leads to the accumulation of acid in the body. Usually, when blood is filtered by the kidney, it passes through the tubules of the nephrons (the functional unit of the kidney).

Before it flows into the bladder from the kidney, the urine undergoes an exchange of salts, acids and other solutes. Renal tubular acidosis results in the formation of excessive amounts of acid because the kidneys cannot drain them. This may happen because the kidneys cannot reabsorb the alkaline bicarbonate ions from the urine in the early segment of the nephron or because of inadequate production of acidic hydrogen ions in the latter half of the nephron.

Renal Tubular Acidosis is simply associated with abnormal urinary acidification. Other functions of the kidneys remain unimpaired.
There are several different types of renal tubular acidosis-

  Distal Renal Tubular Acidosis (RTA)
This is the most fundamental form of RTA. It is characterized when the hydrogen ions are not secreted into the lumen of the nephron by the alpha-intercalated cells of the medullary collective duct of the distal nephron. When this happens the pH of urine cannot be brought down below 5.3. Renal excretion is inhibited and hydrogen ions are not eliminated which leads to academia. At the same time, Potassium ions cannot be absorbed by the cell which leads to hypokalemia. The end result is protein retention and potassium excretion. Distal RTA can lead to the urinary stone formation, calcium deposits in the kidney, rickets and osteomalacia and Sjogren s syndrome.

  Proximal RTA
When proximal tubular cells reabsorb 85% of filtered bicarbonates and 60% of filtered sodium from the urine, then this again leads to academia. The distal intercalated cells, however, function normally and so the academia is not as severe as in case of Distal RTA. The alpha-intercalated cells can acidify urine to a pH of 5.3 or less because they produce hydrogen ions. Proximal RTA is also associated with Fanconi Syndrome which is characterized by aminoaciduria, uricosuria, glucosuria, and tubular proteinuria.

  Combined distal and proximal RTA
Inherited carbonic anhydrase II deficit leads to combined distal and proximal RTA. This is accompanied by osteopetrosis, cerebral calcification, and renal tubular acidosis. Cases of combined distal and proximal RTA are very rare.

How is RTA understood?
The following steps are applied to analyze Renal Tubular Acidosis-
  Determining the anion gap in acidosis. The normal Anion Gap is 8-12 (4-6 mEq/L)
  Separating the renal from the extrarenal causes of normal anion gap acidosis
  Classifying the types of RTA
  If it is distal RTA, further tests will be necessary to support the diagnosis

How is RTA diagnosed?
Three types of tests can reveal if a person is affected by Renal Tubular Acidosis-
  Urine test
  Acid load test
  Physical examination

Treatment of RTA-
Doctors prescribe either or both of the following two types of therapies-

  Alkali therapy- The pH level of urine is restored and electrolytes are balanced
  Vitamin D supplements- If RTA leads to bone deformities or rickets, your doctor will prescribe vitamin supplements to strengthen your bones.

Timely diagnosis can prevent the effects of Renal tubular Acidosis from becoming compounded. With the right medication, a person can lead a healthy normal life.

What Should You Know About Renal Tubular Acidosis?

7 anti-beauty habits that kill your looks the most!

You might be spending a lot to add to your beauty. But there are many bad habits which affect your beauty. Here is the list of the most common terrible habits which might be damaging your skin and health.

1. Squeezing pimples: when you pop a pimple, clogged pore is burst open releasing bacteria. These bacteria come in contact with your rest of the skin and increase the acne. Moreover, habit of squeezing pimples may also leave scars and pock marks. The best way to get rid of pimples is to use medicated/ antibacterial soap and let it heal itself.

2. Licking/ chewing your lips: chewing your lips make them even drier and chapped. It makes you to lick and chew your lips more often. Excessive lip biting also results into bleeding and infection. To avoid this, get yourself a good lip balm and apply regularly to moisturize and protect your lips.

3. Nail biting: nail biting result in ugly hands, fingers and nails due to cuticle biting. It can also result in infections of nails, mouth, finger and dental problems affecting your smile too. Work upon triggers to prevent these issues by yoga, manicure etc.

4. Smoking: smoking affects your skin making it dry and rough. It decreases the blood flow to the skin and damages your collagen and elastic which result into saggy and loose skin. Quit smoking.

5. Sleeping with makeup on: make up clog your skin pores and oil glands, making it difficult to breathe and prone to acne. To avoid this, spare sometime before going to sleep to cleanse your makeup and moisturize the skin well.

6. Ignoring the sunscreen: ignoring sunscreen in summer is exposing your skin to uv rays. Uv rays cause wrinkles and dry your skin giving you the older look. To protect your skin from uv rays, use sunscreen before half n hour of going out.

7. Inadequate sleep: inadequate sleep releases the stress hormone in the body. It also ages your skin by decreasing collagen from skin. Hence try getting enough sleep.

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7 Anti-Beauty Habits That Kill Your Looks the Most!

The three primary functions of the kidney are- eliminating waste materials and toxins from the body, producing hormones that help control your body mechanism and regulating blood pressure. Chronic Renal Failure, also known as Chronic Kidney Disease, refers to the condition where your kidney gradually stops functioning properly over time- weeks, months or years. As the condition worsens, wastes and fluids start to build up in your system instead of being filtered out. This leads to an end-stage renal failure/disease.

What causes Chronic Renal Failure?
Chronic renal failure is caused due to a condition or disease that impairs kidney function. The most common causes are- diabetes (Type 1 and Type 2), polycystic kidney disease, glomerulonephritis, interstitial nephritis. Glomerulonephritis occurs when the filtering units of the kidney become, inflamed. Interstitial nephritis refers to an inflammation in the kidney tubules and its surrounding regions. Prolonged obstruction of the urinary tract due to kidney stones or enlarged prostate, also can cause chronic renal failure.

What are the symptoms that you must watch out for?
Symptoms and signs of chronic renal failure develop gradually over time. Therefore, most of the time people suffering from this condition are diagnosed at the later stage when functioning of the kidney is significantly impaired. Nevertheless, if you encounter signs such as unintentional weight loss, weakness and fatigue, vomiting and nausea, swelling of face and legs, cramps and muscle twitches, change in the urinating pattern, easy bruising, blood in the stools etc., then you should see a doctor and have yourself diagnosed. In case the fluids get accumulated in the lining of your heart or lungs, you may experience chest pain and shortness of breath.

Role of homeopathy in curing Chronic Renal Failure-
Unlike conventional treatment methods which focus on the pathological condition, homeopathy takes a holistic approach to treat the individual. Homeopathy remedies and medicines are natural, and try to rectify the underlying causes of this condition. The medications are selected and prescribed after thorough analysis of the patient s medical history and health condition. A particular remedy is chosen keeping in mind the general symptoms of the condition. Among several homeopathic medicines, the frequently used ones are- Belladonna and a solution made from gold and sodium. Homeopathy remedies reduce swelling of the face, cures kidney inflammations, and reduce severe, recurring pain in the lumbar region. They work by stimulating your immune system so that the damaged kidney and other organs start functioning more correctly.

Homeopathy remedies do not provide substitutes for any organ of your body. They simply repair the damaged organs, improve your overall health and thereby prevent the person from suffering a relapse.

Chronic Renal Failure - How Homeopathic Treatment Is Best For You?

Kidney transplant surgery is a surgical procedure where a healthy kidney is used to substitute a diseased one. The healthy kidney is obtained from either a deceased donor or a family member who has a good blood type match with the recipient. Usually, the recipient receives one kidney if the donor is alive and/or both the kidneys from a deceased donor.

Certain reasons for going for a kidney transplant surgery might include:
1. Kidney failure due to diabetes
2. Infections in the urinary tract
3. Autoimmune disorders such as lupus (an autoimmune disorder)
4. Polycystic kidney disorders
5. Obstructions in the kidney
6. Glomerulonephritis, where inflammation occurs in the kidney

Preparation for the surgery
Before the procedure, certain tests are carried out to determine your suitability for the procedure. The tests start with a psychological evaluation followed by blood tests and diagnostic tests to check for health problems. Once the tests are done, you will be placed on the waiting list for kidney recipients. Once the donor is available, you will be asked to get ready for the surgery.

Procedure: The procedure begins with you being administered general anesthesia. An incision is made in the lower part of the stomach, through which the donated kidney is inserted in the body. The next step involves attaching adjacent blood vessels to the kidney so that it has a proper supply of blood. Finally, the ureter of the kidney is linked with the bladder, facilitating normal disposal of bodily wastes. A plastic tube, known as a stent, is placed in the ureter to facilitate urine flow. This is later removed by a procedure called cystoscopy. Once the surgery is completed, the incision is closed by stitches.

Aftercare: After the procedure is completed, you will be given painkillers to ease the pain. Immunosuppressant medications will be prescribed to prevent your immune system from destroying the cells of the donated kidney. Usually, the duration of stay at the hospital post-surgery is about a week. 

Kidney Transplant Surgery and What You Should Know About It

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