The liver has a significant role to play in metabolism and digestion. The failure of a liver can lead to significant health issues. There are some causes for liver failure, which cannot be treated with medications. In these people, a transplant, which is replacing the diseased or injured liver with another liver, is the only definitive treatment option.

Some conditions which can require a liver transplant are:

Severe cirrhosis with a life expectancy of less than a year
Severe liver failure
Non-alcoholic steatohepatitis (NASH)
Liver cancer
Chronic hepatitis C
Biliary atresia in children
Types of transplant:

Living donor transplant: In some patients, partial liver can be removed from a close family member and transplanted into the affected individual. The liver is known for its regeneration ability, and over time, will grow in the recipient.
Cadaveric transplant: Immediately after death, a liver can be removed and transplanted.
While the concept of a transplant sounds quite convincing and appealing for those with a severe liver disease, it is also important to note that not all would qualify for a liver transplant. The conditions which would disqualify a recipient are discussed below:

Significant heart disease: Those with severe coronary artery disease, valvular disease, cardiomyopathy, aortic stenosis, and cardiomyopathy are not candidates for a liver transplant.
Severe lung disease: Those with poor lung perfusion do not qualify for a liver transplant.
Advanced age: Greater the age, lesser the survival rates. So, people aged more than 70 are usually not considered for a transplant.
Obesity: A person with a BMI of more than 35 is often not a good candidate for a transplant. The overall health should be managed in these people.
Malnutrition: On the other extreme, severely malnourished individuals are also not considered for a transplant.
HIV infection: A person who is HIV-infected does not qualify for a liver transplant.
Substance abuse: Anyone who is actively abusing alcohol and/or substances is definitely removed from the list for a transplant.
Metastasis: If a patient is looking for a liver transplant due to hepatic cancer, it is essential that the cancer is contained. If it has spread to various parts, then containing it would be difficult, and a transplant may not succeed.
Multisystem organ failure: Other than heart and lungs, even people with poor renal function are not ideal candidates for a liver transplant.
A detailed liver recipient evaluation assessing the severity of liver disease, chances of survival, and overall health are done before a person is listed for liver transplant. This evaluation ensures a better success rate with the transplant.

Common Surgical Complications That One Should Be Prepared For?

Hectic lifestyle, unhealthy food habits, poor bowel movements, and stress can all add up to one condition called the GERD. Gastroesophageal reflux disease or GERD refers to a particular type of digestive disease, and mainly affects the LES or lower esophageal sphincter, which is a muscle ring between the stomach and the esophagus resulting in the symptoms such as burning sensation in the chest or difficulty in swallowing.

Treatment options
While the moderate or mild GERD can usually be treated with healthy lifestyle changes, diet, and medications, when the condition gets severe, surgery becomes the only option to prevent the issue from deteriorating further. Here are some of the common surgical options available for treating GERD:

Fundoplication: This surgical procedure is the most common and standard surgical option for treating GERD. It focuses on tightening and reinforcing the LES by wrapping the upper portion of the stomach around the outer side of the lower esophagus which strengthens the sphincter.
Transoral Incisionless Fundoplication: Transoral incisionless fundoplication or TIF is another surgical procedure available for treating GERD and can be performed when an open fundoplication cannot be performed. It is performed by creating a barrier between the esophagus and the stomach which prevents the stomach acid from reflux or going backwards.
Stretta: This surgical procedure is performed as an outpatient option using an endoscope. Here, a flexible tube is passed into the esophagus where the electrode present at the tip of the tube creates tiny cuts on the esophagus by heating the esophageal tissues. As a result, the scar tissues formed, block the nerves that are responsible for acid reflux.
Bard EndoCinch System: This surgical procedure also uses an endoscope to create stitches to make pleats in the lower esophageal sphincter, which strengthens the LES. However, this surgical treatment option is not as common as other GERD treating procedures.
Linx Surgery: In Linx surgery, a special device called Linx, a ring containing microbeads of magnetic titanium, is wrapped around the sphincter to make it strong. As the beads are magnetized, they help in keeping the opening between the esophagus and stomach closed, while letting the food pass normally.
Recovery
As long as the surgical option is laparoscopy, they are the least time-consuming as well as less painful with lesser downtime, but may not be ideal for everyone. When it comes to traditional surgical treatment options like fundoplication, it takes around minimum six weeks to resume the daily activities. However, for laparoscopic fundoplication, the downtime is one or two weeks. Linx surgery is a minimally invasive surgical option and therefore, the recovery time is shorter than other traditional surgeries for treating GERD. Depending on the patient's health conditions and response to surgery, the recovery time may vary for each surgical treatment options for GERD.

So, seek the advice of your gastroenterologist for the best possible treatment option to get completely cured of the condition.

Treating GERD: 5 Surgery Options That Can Help!

Obesity can make life miserable. From unhealthy eating habits to unhealthy lifestyles and medical conditions, obesity can be an amalgamation of many factors. Obese people are a greater risk of suffering from many serious health complications like type-2 diabetes, mood swings, and depression, cardiac problems, high blood pressure and high cholesterol, to name a few. It does not stop there. More alarming is the fact that obese people are an increased risk of suffering from different types of cancer.

Bariatric surgery comes as a saviour for highly obese people (with a BMI over 40), who have tried every possible treatment under the sun to lose weight without any success. Bariatric surgery has helped many severely obese people attain a healthy weight. Bariatric surgery can be of three types;

Gastric bypass surgery (Roux-en-Y): This is one of the most common types of weight-loss surgery practised worldwide. The procedure involves rearranging (dividing) the stomach into a smaller upper pouch and a larger lower part. The smaller pouch is then connected to the small intestine. The food consumed will pass into the small intestine through the pouch. The idea is to rearrange the stomach in such a way that a person consumes a lesser quantity of food.
Gastric banding (Laparoscopic Adjustable Gastric Band): In this procedure, the surgeon creates a small pouch at the upper part of the stomach by placing a band (lap band or A-band) around it. The pouch, true to its name, is used to hold the food consumed. The purpose of placing a band around the stomach (upper part) is to reduce the intake of food.
Sleeve Gastrectomy (Gastric Sleeve surgery): In Sleeve Gastrectomy, surgeons remove a large portion of the stomach, leaving behind only a small sleeve-like pouch (hence the name). Like the other two surgeries, sleeve gastrectomy also aids in limiting the consumption of food.
Duodenal switch: The fourth type of bariatric surgery, Duodenal switch with biliopancreatic diversion, is not very commonly used. Bariatric surgery has several health benefits. In addition to the weight loss, it plays a pivotal role in lowering the incidences of Type-2 Diabetes, depression, anxiety, coronary artery problems, sleep apnea cardiovascular diseases.
Research also suggest that bariatric surgery has been instrumental in reducing the chances of cancer (especially colon and breast cancer) by as much as 60%. The correlation between weight loss and reduced cancer instances is still a debatable topic. Some researchers and oncologists believe that the weight loss (bariatric surgery) brings about a hormonal modification which prevents the growth of tumour cells. Another study links obesity with an increased inflammation. In many cases, inflammation acts as a catalyst, accelerating the growth of cancer cells. Research is still going on to understand this correlation (obesity and reduced cancer rates) better.

Bariatric surgery has its share of risks and demerits. Consult your physician and get yourself thoroughly examined before opting for the surgery.

Does Bariatric Surgery Reduces The Risk Of Cancer?

Ovarian cysts are fluid-filled sacs that develop on a woman's ovary. A patient might experience abdominal and pelvic pain, abnormal bleeding, menstrual irregularities, pain during intercourse or irregular bowel movements. These symptoms indicate an ovarian cyst developing inside you. Ovarian cysts are common in women and may develop during menstruation. In many cases, symptoms are not observed, and you may get ovarian cysts without knowing. Usually being harmless, ovarian cysts may sometimes lead to severe health conditions.

Here are 7 important things you should know about ovarian cysts:
1. You should know the reason behind the formation of ovarian cysts. When the follicle does not release the egg, it may grow bigger in size and take the form of a follicular cyst. A corpus luteum cyst may also develop, which is a cavity that gets formed after the egg is ruptured and released from the follicle. The cysts may bleed and cause pelvic pain.

2. It is important for you to know if you have an ovarian cyst. Many ovarian cysts do not show symptoms and go away by themselves. Follicular cysts do not change your menstrual cycle, but corpus luteum cysts may cause bleeding.  

3. You should know how to detect an ovarian cyst. You should visit a gynecologist regularly for diagnosis. Bigger cysts can be diagnosed via a pelvic examination. Ultrasound is also used for detection.  

4. You should have an idea about all the symptoms associated with ovarian cysts. These include fever, nausea and vomiting. These symptoms indicate that you have an infection. Sometimes, a cyst might twist an ovary, which may cut off blood supply to the ovary, causing permanent damage.

5. In case you are at a risk of twisting of the ovaries, you have to undergo a surgery. Surgery is also considered when the cyst lasts longer than three menstrual cycles and it is bigger than four inches in size. The cyst may also pose the risk of being a tumor. The common surgical procedures for ovarian cysts are laparoscopy and laparotomy.  

6. You can prevent ovarian cysts be taking birth control pills, which help in suppressing ovulation and prevent the formation of a cyst. Birth control pills may help only if you are not pregnant.

7. Ovarian cysts are more common in premenopausal women. However, these are possible in postmenopausal women as well, especially in the early postmenopausal stage.  

Sometimes, there might be chances of an ovarian cyst being cancerous in nature, which may lead to ovarian cancer. The risk of cancerous ovarian cysts increases with age. It is recommended to consult a gynecologist for the proper diagnosis and treatment of ovarian cysts in women. Pain medications and heating pads are used as alternative treatment methods for less serious ovarian cysts.

7 Things You Should Know About Ovarian Cysts

The tube that carries food to your stomach from your throat is called the oesophagus. When the muscular valve (lower oesophagus sphincter) in the oesophagus fails to relax and carry the food to the stomach, the condition is termed as achalasia.

Achalasia has a variety of causes, and can be difficult for your doctor to diagnose the exact cause. Some common causes of Achalasia include:
1. Hereditary predispositions
2. Autoimmune disorders (The immune system erroneously destroys healthy cells in the body)
3. Nerve degeneration in the oesophagus
There other medical conditions that often lead to symptoms identical to achalasia, such as oesophageal cancer and Chagas  disease (an infectious disease caused by a parasite).

Other symptoms of achalasia include:

The most prominent symptom of achalasia is dysphagia, which is characterised by swallowing difficulties or sensations of food stuck in the oesophagus. Dysphagia often triggers coughing and shortness of breath or choking on food.
1. Discomfort or pain in the chest
2. Weight loss
3. Heartburn
4. Intense discomfort or pain after eating

Some of the treatments include:

Most of the methods to treat achalasia focus on the lower oesophageal sphincter (LES). The treatments used can either permanently alter the sphincter s function, or reduce symptoms.
1. Oral medications such as calcium channel blockers or nitrates are prescribed, which can relax the LES to let food pass through with more ease. Your doctor may also treat the LES with Botox.
2. For a more permanent treatment, the sphincter can be dilated or altered. In dilation, a balloon is inserted into the oesophagus and it is inflated. This will stretch out your oesophagus to improve function.
3. To alter the oesophagus, oesophagomyotomy is performed. It is a kind of surgery where minimal incisions are made to gain access to the LES, and then it is carefully altered to improve flow of food to the stomach.

Unlike dilation, which can cause complications such as tears in the oesophagus, oesophagomyotomy has a greater success rate. However, certain complications may still arise, such as:
1. Acid reflux
2. Respiratory conditions that are caused by food entering your windpipe

Achalasia - Can Autoimmune Disorders be the Cause Behind it

What is DVT?

Deep vein thrombosis is a kind of vascular disorder. It happens when a thrombus (blood clot) forms in the deep vein anywhere in the body. It especially develops in the legs. This is a grave ailment and can actually be fatal for you unless you seek treatment right away.

What are the symptoms of DVT?

A worrying feature of deep vein thrombosis is that in most cases it shows no symptoms in the earlier phases. Moreover, what makes diagnosis hard is that even when symptoms manifest, they are very similar to those of other disorders like tissue or muscle inflammation or arthritis.

Here are some typical deep vein thrombosis symptoms:

  One or both of your legs become swollen
  Your legs feel tender and hurt a lot in all postures
  The skin of your legs always feel hot to the touch
  Your skin looks blotchy or discoloured
  You bleed when you cough
  Wheezing and breathing problems
  Dizziness
  Frequent and sharp chest pain

Who is susceptible to DVT?

Deep vein thrombosis usually happens when you sit or lie in one position for long stretches of time especially when you are recuperating after an illness or surgery. It can also happen to you for other reasons-

  Injury: An injury to your legs can narrow the blood vessels and that reduces the blood flow through the veins. That is why blood clots can develop there.
  Pregnancy: The additional weight that woman has to carry in the course of her pregnancy exerts extra pressure on the veins of the legs and pelvis and thus clots may form in the veins.
  Contraceptive pills: Birth control pills raise the chances of a woman getting deep vein thrombosis by four times.
  Obesity: Obesity means forcing extra pressure onto your veins.
  Smoking: Smoking interferes with the flow of blood through your veins and raises the possibility of getting blood clots.
  The family history of deep vein thrombosis: if anyone in your family has deep vein thrombosis, you might contract it too because it is hereditary.

Complications:

DVT becomes lethal if the blood clot becomes dislodged and travels from the legs to the lungs, it can cause a pulmonary embolism. This can lead to blockage of the artery of the lung and in that case, a person may die.

Treatment for deep vein thrombosis:

Treatment for DVT includes both invasive and non-invasive vascular techniques.

  Blood-thinning medicines: They prevent blood platelets from clumping together and reduce the size of the existing clots.
  Thrombolytic drugs: If medicines are not effective, work, these drugs will be injected into your veins. They travel down the veins to where the blockage is and disintegrate the clots so that blood can once again flow through the vein uninterrupted.
  Compression stockings: They exert pressure on the vein containing the clot, prevent it from moving, and do not allow new clots to develop. You have to wear them throughout the day.
  Surgery: In very rare cases, when non-invasive methods have no effect, you may have to undergo a kind of vascular surgery called venous thrombectomy. The surgeon will make a minute incision in the vein where the clot is lodged, siphon it out and then repair the damaged vein.

Deep vein thrombosis is easily curable with treatment. Do not delay it, as DVT has the potential to kill you.

Deep Vein Thrombosis (DVT) - All You Should Know About It!

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