Skin cancer occurs when the DNA of the cells undergo mutations, thus causing unsystematic cell growth which evolve into a cancerous mass. This abnormality stems from the over-exposure of your skin to the Ultraviolet Radiations of the sun. 

However, there are other factors too that escalate the risks of skin cancer.

Fairer skin tone: Inadequate pigmentation or melanin content in the skin offers less protection against the harmful UV radiations. Having red or blond hair or light-colored eyes makes you more vulnerable to this condition.
Sunburns: A history of sunburns can often be the root cause behind skin cancer.
Excessive exposure to the sun: If you spend a considerable amount of time under the sun and especially if your skin is not protected by clothing or sunscreen, you tend to get a tan. A tan is the skin s response to extreme UV radiations.
Moles: Abnormally large moles, known as dysplastic nevi, are more likely to turn malignant. Watch out for any change in the texture of the moles, which is one of the most important symptoms of skin cancer.
Family history: According to studies, genes are considered to be one of the causes behind skin cancer. Hence, a family history of this condition could spell trouble for one.
Personal history: Having suffered from skin cancer previously in life could endanger one even more.
Pre-cancerous skin injury: Skin lesions, also known as actinic keratosis, make you prone to developing pre-cancerous growths on the skin. These could appear as scaly rough patches, ranging from brown to pink in color. They usually crop up on the hands, head and faces of people who are comparatively of a fairer skin tone.
A weak immune system: People having a poor immunity system, including the ones affected by HIV/AIDS or are on immunosuppressant drugs which follow any organ transplantation have greater risks of developing cancer.
Exposure to radiation: Radiation therapy is an often used treatment method for treating various skin conditions such as acne and eczema. Having been exposed to radiations, one could be indisposed to this condition even more.
Exposure to certain chemicals: Exposure to certain substances such as arsenic might increase your vulnerability manifold.

Skin Cancer - 10 Things That Can Increase Your Risk!

Cancer is the abnormal, uncontrolled growth of cells in a particular body part. With continued growth, pieces of this tissue travel through the blood to different body parts and continue to grow in the new area. This is known as metastases. Breast cancer is one of the most common forms of cancer and affects about 1 in 8 women in the USA. Read on to know more details of breast cancer   breast anatomy, causes, symptoms, risk factors, detection, prevention, and of course treatment.

Anatomy: The main function of the breast is lactation through its milk-producing tissue that are connected to the nipple by narrow ducts. In addition, there is surrounding connective tissue, fibrous material, fat, nerves, blood vessels and lymphatic channels which complete the structure. This is essential to know as most breast cancers develop as small calcifications (hardened particles) in the ducts or as small lumps in the breast tissue which then continues to grow into cancer. The spread can happen through lymphatic or blood flow to other organs.

Warning signs/symptoms: The following are some symptoms that need to be watched out for if you have a predisposition to breast cancer.

    A lump in either of the breasts or armpits
    Change in size, shape, or contour of either breast
    Redness of your breast or nipple
    Discharge of clear or bloody fluid
    Thickening of breast tissue or skin that lasts through a period
    Altered look or feel of the skin on the breast or the nipple (dimpled, inflamed, scaly, or puckered)
    One area on the breast that looks very different from the other areas
    Hardened area under the breast skin

Either one or a combination of these should be an indication to get a detailed checkup done. Early diagnosis results in controlling the disease with minimal treatment and reduced complications.

Causes and risk factors: The exact cause for breast cancer is yet to be pinned down. However, risk factors are clearly identified, and women with risk factors need to watch out for warning signs.

    Family history: Of all the risk factors, the family history is the most important. Breast cancer runs in families, and if there is a first-degree relative with the breast cancer, the chances of developing it are almost double. Two genes BRCA1 and BRCA2 are the carriers of the disease, and this testing can be done in women to identify if they are at risk.
    Family history of other cancers: Even if there is no breast cancer, if there are other cancers that run in the family, watch out.
    Age: Women over 50 are at higher risk of developing breast cancer.
    Race: Caucasian and Jewish women are at higher risk of breast cancer than African-American women.
    Hormones: Greater exposure to the female hormone estrogen increases the chances of developing breast cancer. Women who use birth control pills for contraception and hormone replacement after menopause are at a higher risk of developing breast cancer.
    Gynecologic milestones: Women who have abnormal menstrual milestones need to watch out. These include those who attain menarche before 12 years of age, get pregnant after 30, attain menopause after 55, and have menstrual cycles shorter than 26 days or longer than 29 days.
    Obesity and alcohol abuse are also likely to increase a woman s chances of developing breast cancer.

Stages: Starting from stage 0, higher stages indicate advanced disease.

    Stage 0: The growth which has begun in the milk-producing tissue or the ducts has remained there (in situ) and not spread to any other area, including the rest of the breast.
    Stage I: The tissue slowly becomes invasive and has begun to affect the surrounding healthy tissue. It could have spread to the fatty breast tissue and some breast tissue may be found in the nearby lymph nodes.
    Stage II: The cancer at this stage grows considerably or spreads to other parts. There are chances that cancer may grow and also spread.
    Stage III: It may have spread to the bones or other organs but small amounts are present in up to 9 to 10 of the lymph nodes in the armpits and collar bones which makes it is difficult to fight.
    Stage IV: The cancer is widespread to far-flung areas like the liver, lungs, bones, and even the brain.

Screening: This is one of the most effective ways to identify the disease in its early stages. This will help in controlling cancer from spreading with minimal treatment.

    Self-examination: A thorough self-examination to look for changes in terms of shape, size, colour, contour, and firmness should be learned by all women. Watch for any discharge, sores, rashes, or swelling in the breasts, surrounding skin, and nipple. Examine them while standing and when lying down.
    In most women, annual screening mammograms are advised after the age of 40. However, in women who have a strong family history or genetic makeup, it is advisable to have screening mammograms starting at age 20 every 3 years and then annually from the age of 40.
    Women in high-risk categories should have screening mammograms every year and typically start at an earlier age.
    Ultrasound screening can also be given in addition to mammograms.
    Breast MRI is another way to screen for breast cancer if the risk is greater.

Breast Cancer Prevention: Now that there is so much awareness about causes and risk factors, there are definitely ways to prevent or delay the onset of the disease.

    Exercise and a healthy diet with reduced amount of alcohol are definitely effective in minimising the chances of developing cancer.
    Tamoxifen is used in women who are at high risk for breast cancer.
    Evista (raloxifene) which is used to treat osteoporosis after menopause. It is also widely used in preventing breast cancer.
    In high-risk women, breasts are surgically removed to prevent the development of cancer (preventive mastectomy).

Treatment: As with all cancers, treatment would depend on the stage at which it is identified and include a combination of chemotherapy, radiation, and surgery. As noted earlier, if you are at risk, look out for warning signs as early diagnosis is the key to maximum recovery.

Breast Cancer - Know More to Say 'No' More!

Brain metastases from systemic cancer are the most common type of intracranial neoplasm in adults, being almost 10 times more common than primary malignant brain tumors, which cause a significant burden on the management of patients with advanced cancer (1). The lungs represent one of the most frequent sources of metastases to the brain, with a probability of (36 64%) (3). Symptoms suffered by the patients include headaches, epilepsy, focal weakness, numbness or changes in mental status. The prognosis of patients with brain metastases is not optimistic and the median survival time is  1 2 months if left untreated. The 1-year survival rate has been recorded as 10.4% (4,5). The treatment of metastatic brain tumors is complex; not only due to being able to provide local control and improve neurological function, but also due to factors such as age, performance and systemic disease status and the size, volume, location and number of metastases at presentation

CyberKnife is a robotic radiosurgery system with a linear particle accelerator (linac), which is coupled with real-time imaging to track and compensate for the patient s or target s motion. As a relatively non-invasive treatment modality, CyberKnife demonstrates certain benefits, including a more accurate target localization and improved dose delivery for the management of metastatic brain tumors that allows higher biologically effective dose delivery without increased incidence of toxicity.

In the present case, the results for the treatment of multiple brain metastases after CyberKnife surgery with a 7 8 Gy marginal dose was promising. CyberKnife for metastatic brain tumors is an effective and safe method for reducing the marginal dose prescribed for multiple brain metastases and for minimizing the radiation-related neurotoxicities. In conclusion, CyberKnife, a focused, highly-targeted radiosurgery and fractionated radiotherapy is particularly useful for multiple brain metastases. CyberKnife provides the advantage of the management of local recurrence and a tolerable complication rate. Although the treatment of brain metastases has been performed with CyberKnife, the clinical significance and optimal dose fractionation scheme require further investigation.

In case you have a concern or query you can always consult an expert & get answers to your questions!

CyberKnife Therapy Of 24 Multiple Brain Metastases From Lung Cancer!

Lung cancer is caused by disorderly growth of uncommon cells which line the air passage, usually starting off in a single or both lungs. The irregular cells do not mature into healthy lung tissue but instead divide speedily and result in tumor formation.

Causes behind lung cancer:

Smoking: This is considered as the most significant source of lung cancer. As reported by multiple researches and studies, cigarettes contain over 4,000 chemicals, most of which are cancer causing agents. Active smoking is one of the major causes of lung cancer but what may come to you as a surprise is that extended periods of passive smoking is also a major factor.
Pollution and Exposure: There is high risk of lung cancer development when there is occupational exposure to pollution by chemicals released from industrial factories. Chemical exposure of this kind refers to prolonged exposure over quite few months or years. Some examples of these chemicals are asbestos, diesel exhaust among many others.
Radioactive Gas: Radioactive gases naturally occur in small masses present in all soils and rocks. However, if you breathe in radioactive gases your lungs will damage and may cause the development of abnormal tissue which can cause lung cancer.
Family history: A family history of cancer, especially lung cancer will also put you at high risk of developing lung cancer.
Treatment methods of lung cancer:

Chemotherapy: Chemotherapy is a method in which drugs are injected through veins in your arm (intravenously) or orally or in a combination of both. These drugs kill cancer cells and help to stop it from spreading any further as well.
Clinical Trials: These trials are experimental lung cancer treatment studies. You may have to try out this clinical therapy if other treatment methods aren t working and only if you are accepted into it.
Surgery: A surgeon will help remove affected areas of the lung including cancerous tumors via surgery. The surgeon may need to remove parts of the lung along with the cancerous growth. In certain cases, one side of the lung may also be completely removed to stop the spread of the malignant tissue.
Radiation Therapy: This is a therapy where high energy electromagnetic waves are passed through your body to destroy cancer cells with the help of high-powered energy beams.
Can you prevent lung cancer?

Nutrition -- A  healthy diet with lots of fruits and vegetables may also help reduce your risk of lung cancer. Some evidence suggests that a diet high in fruits and vegetables may help protect against lung cancer in both smokers and non-smokers. But any positive effect of fruits and vegetables on lung cancer risk would be much less than the increased risk from smoking.
Exercise -- Even moderate amounts of exercise can aid in lung cancer prevention. Studies suggest that even something as simple as gardening twice a week is associated with a lower risk of developing lung cancer.
Smoking Habits -- If you stop smoking before a cancer develops, your damaged lung tissue gradually starts to repair itself. No matter what your age or how long you ve smoked, quitting may lower your risk of lung cancer and help you live longer. 
Avoidance of Air Pollution -- Long-term exposure to ambient air pollution and, in particular, particulate matter with absorbed polycyclic aromatic hydrocarbons and other genotoxic chemicals has been suspected to increase the risk for lung cancer. So, avoid air pollution as much as possible.

Lung Cancer - Ways You Can Prevent It!

International Childhood Cancer Day is celebrated annually on 15 February to raise awareness and to express support for children and adolescents with cancer, survivors and their families.
We live in an age where every single individual, more or less, is exposed to the risk of cancer. It is probably an unfavorable lifestyle we lead that deprives us of good health. This might alarm many but considerable changes in lifestyle can help you realize cancer as a preventable disease. Cancer does not only make you undergo severe suffering but it also affects your friends and family. The pallor of misery spreads wider than you think.

A balanced and nutritious diet: Deciding on a plant- based diet or a Mediterranean diet can aid your fight against the risk of cancer. A Mediterranean diet will involve green leafy vegetables, lots of fresh fruits, whole grains, mixed nuts, legumes and also the use of extra- virgin olive oil. Fish can be a safe bet but red meat should be avoided. One must also try to avoid processed meat as they tend to make you prone to the risk of cancer.
Immunization: Hepatitis B and HPV or Human papilloma virus vaccines are extremely necessary to protect you against the every types of cancer.
Sun protection: Caring for your skin doesn't arise from vanity. Skin cancer is one of the most prevalent kinds of cancer; the chances of this disease can be restricted by remaining in shade especially during midday, by wearing covered clothes and by using a good sunscreen lotion repeatedly while outside.
Exercise diligently: Did you think it was okay to have weaker muscles and bulging layers of fat? If yes, you probably have grown numb to the inadequacies you face in result. Unchecked fat can lead to obesity which further complicates health conditions. Metabolic activity differs from person to person. Regular exercising can help regulate metabolism according to the needs of your body. Physical exercise protects you against the risk of breast and colon cancer. Moderate or vigorous physical activity for 150 to 75 minutes a week respectively can reduce the risk of cancer.

International Childhood Cancer Day - Few Tips to Reduce the Risk of Cancer

A breast lump is an enlargement, swell, protuberance or a bump that is different than the breast tissue surrounding it. Breast lumps can appear in men as well as women and they can be benign or malignant. Causes of benign breast lumps are as follows:

Fibroadenosis: Also known as Fibro-cystic breast disease, it is a benign condition that affects the breast. It may affect either of the breasts or both. One of the major symptoms of Fibroadenosis is a breast lump. Usually, the lumpiness disappears after the menstrual cycle is over. Fibroadenosis occurs because the breast tissue doesn t respond well to the hormonal changes during the menstrual cycle.
Fibroadenomas: Fibroadenomas occur because of abnormal response to the hormone oestrogen. The lumps are usually well formed and round, around the milk ducts of the breast. Breast lumps due to Fibroadenomas are called breast mice, because they move around the breast. In some cases, they disappear and in some, they tend enlarge during pregnancy.
Other benign causes of breast lumps are breast abscesses, breast cysts, lipoma (lump of fat), mastitis (infection in the breast tissues), fat necrosis (another name for breast lumps) and intraductal papilloma (benign tumour of the milk ducts in the breast). A breast lump that is firm, well defined and doesn t move around, i.e. it doesn t disappear after your period or pregnancy, may be a result of breast cancer.

Treatment of breast lumps
The treatment of a breast lump depends on its cause. Benign breast lumps usually disappear over time. Otherwise following treatments can be considered as per the doctor s discretion-

Medication: If the breast lumps are painful or increase over time, it is advisable to take medication.
Non-steroidal anti-inflammatory drugs (NSAIDs) and other painkillers like paracetamol
Danazol, Tamoxifen or Bromocriptine are administered to treat breast pain as well
Antibiotics which are administered to cure breast abscesses that are caused due bacterial infections
Limiting the amount of fat in the diet or wearing well fitting bras also reduces the amount of pain due to breast lumps.
Certain types of breast lumps are filled with fluid or pus. This fluid can be drained through a procedure called aspiration or drainage.
A radical way to treat a breast lump is surgery. Many a times, these lumps get bigger and painful and the most effective way to deal with it is to remove it.

Breast Lumps - How Can They Be Treated?

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