What is Allergic Asthma?

Allergic asthma is the condition in which the symptoms of an asthmatic attack appear after exposure to certain allergens. 90% of the cases of asthma in children are allergy driven, while in adults, the percentage is said to be around 50%.

An allergy happens when an individual's immune system exhibits massive reaction or fights vigorously against substances like pollen, dust, animal dander or certain other minute particles which are actually not harmful to the body but are considered so by the immune system.

Symptomatic changes in cases of allergic asthma:

If the symptoms of an asthma attack occur only when you are subjected to these triggers or irritant particles, your case is allergy driven.

In such cases, the airway reacts aggressively to the entry of such allergens.

The airway muscles tighten up and inflammation is observed.

Breathing becomes painful and compromised, and mucus accumulation sets in very quickly.

Coughing is a common phenomenon, as the body tries to expel the mucus accumulated.

The allergens mentioned above are not the only triggering agents. Basically, anything that causes irritation could trigger an allergy and an asthmatic attack thereafter. Symptoms in the case of allergy driven asthma are more or less the same as seen in other asthmatic cases.

Confirming the cause of asthma as allergic or not:

The doctor would give you a much better clarification on whether you're asthma is allergy driven or not. There are pretty much two ways to decipher the same:

One is to administer a tiny amount of allergen to the skin and making a note of the reaction to that. Whether the reaction is a normal one or an aggressive one would tell if an individual has an allergy or not.

Specific IgE test may be done to confirm the cause, or to test the presence of an allergic reaction in the individual.

All your queries pertaining to allergic asthma and asthma, in general, are more than welcome.

What is Allergic Asthma?

Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. These abnormal cells do not carry out the functions of normal lung cells and do not develop into healthy lung tissue. As they grow, the abnormal cells can form tumors and interfere with the functioning of the lung, which provides oxygen to the body via the blood.

Lung cancer is the most common cause of death due to cancer in both men and women throughout the world. According to the U.S. National Cancer Institute, approximately one out of every 14 men and women in the U.S. is diagnosed with cancer of the lung at some point in their lifetime. Lung cancer is predominantly a disease of the elderly; almost 70% of people diagnosed with lung cancer are over 65 years of age, while less than 3% of lung cancers occur in people under 45 years of age.

What Causes Lung Cancer?

The development of lung cancer is strongly associated with cigarette smoking, approximately 90% of lung cancers are attributable to use of tobacco. Pipe and cigar smoking can also cause lung cancer, but the risk is not as high as with cigarette smoking. Tobacco smoke contains more than 4,000 chemical compounds, many of which are cancer causing (carcinogens). Passive smoking, i.e. the inhalation of tobacco smoke by non-smokers who live or work with smokers, is also an established risk factor for the development of lung cancer.

Genetic susceptibility (i.e. family history) may play a role in the development of lung cancer. Other causes of lung cancer include air pollution (from vehicles, industry, and power generation) and inhalation of asbestos fibres (usually in the workplace).

Lung Cancer Symptoms

Early symptoms and signs of lung cancer

There may be no symptoms at the onset of the disease. When present, common symptoms of lung cancer may include:

Coughing: This includes a persistent cough that doesn't go away or changes to a chronic smoker's cough, such as more coughing or pain.
Coughing up blood: Coughing up blood or rust-colored sputum (spit or phlegm) should always be discussed with your doctor.
Breathing Difficulties: Shortness of breath, wheezing or noisy breathing (called stridor) may all be signs of lung cancer.
Loss of Appetite: Many cancers cause changes in appetite, which may lead to unintended weight loss.
Fatigue: It is common to feel weak or excessively tired.
Recurring infections: Recurring infections, like bronchitis or pneumonia, may be one of the signs of lung cancer.
Signs of advanced stages of lung cancer

Advanced stages of lung cancer are often characterized by the spread of cancer to distant sites in the body. This may affect the bones, liver or brain. As other parts of the body are affected, new lung cancer symptoms may develop, including:

Bone pain
Swelling of the face, arms or neck
Headaches, dizziness or limbs that become weak or numb
Jaundice
Lumps in the neck or collar-bone region
Treatment

Treatment for cancer involves a combination of surgery to remove cancer cells, chemotherapy and radiation therapy to kill cancer cells. Lung cancer is incurable unless complete surgical removal of the tumour cells can be achieved. Surgery is the most effective treatment for lung cancer, but only a few percentage of lung cancers are suitable for surgery i.e. Stage I and II NSCLC and cancer that has not spread beyond the lung.

Radiation therapy may be used for both NSCLC and SCLC and is a good option for people who are not suitable for surgery or who refuse surgery. Chemotherapy is used for both NSCLC and SCLC. Chemotherapy drugs may be given alone or in combination with surgery or radiation therapy. Chemotherapy is the treatment of first choice for SCLC since it has usually spread extensively in the body by the time it has been diagnosed.

Also used in the treatment of lung cancer are targeted therapies. These are drugs (gefitinib and erlotinib) or antibodies (cetuximab, bevacizumab) that block the growth and spread of cancer by interfering with specific molecules involved in tumor growth and progression. They are used in some patients with NSCLC that does not respond to standard chemotherapy.

Lung Cancer: Causes, Symptoms and Treatments

Without our lungs, it would be impossible to breathe. People suffering from chronic lung diseases have compromised lung functioning. This leads to shortness of breath, fatigue and weakness. In turn, this can make the person avoid anything that exerts the lungs such as exercise. While this may seem like a good idea, it is actually detrimental. Not exercising can further weaken the lungs and muscles and make this a vicious cycle. This is where physiotherapy can help with lung rehabilitation or pulmonary rehabilitation.

Physiotherapy is a branch of medicine that treats diseases and health conditions with exercise and manual therapy. Physiotherapists may also use radiation, sound waves, electric therapy, prosthesis and assistive devices. The aim here is not to cure the disease but to improve lung functioning and the patient s quality of life. Pulmonary rehabilitation can help in a number of ways.

It reduces breathlessness: As the lung muscles weaken, their ability to pump oxygen and transport it to the other parts of the body reduces. This can make a person feel breathless even with the slightest exertion. Lung rehabilitation works on strengthening the lung muscles to reduce this breathlessness.
It increases muscle strength in the arms and legs: When oxygen does not reach the limbs, they, in turn, get weaker. By strengthening the lungs, lung rehabilitation increases the muscle strength in the patient s arms and legs.
It increases stamina and endurance: Stamina is directly linked to lung functioning. By helping the patient breathe more comfortably, lung rehabilitation increases the patient s stamina and helps him or her endure more physical exercise.
It helps patients understand your condition: Physiotherapy is part exercise and part education. By helping patients get an insight into their condition, physiotherapy helps them come to terms with their limitations and motivates them to work harder towards overcoming them.
It increases self-confidence: Feeling breathless and tired all the time can make people feel frustrated. This is especially so because these things cannot be controlled without help. Physiotherapy teaches patients how to deal with these issues and thus increases their confidence in dealing with their medical issues.
It makes patients more independent: A lack of energy can make people dependent on others. Even simple tasks like getting a bottle of water from the fridge can seem like a tiring task. Physiotherapy improves lung functioning and hence makes the person feel less tired doing everyday tasks. This makes the person more independent and improves their quality of life.

Lung Rehabilitation With Physiotherapy!

COPD, also known as Chronic Obstructive Pulmonary Disease is a chronic medical condition that triggers extensive damage to the lungs, interfering with its functioning. In COPD, the lungs and the air sacs or the alveoli undergo severe inflammation that gives rise to a host of complications including wheezing, shortness of breath and other related breathing troubles. While an early medical assistance is instrumental in proper management and treatment of COPD, in most cases, the associated symptoms and discomfort appear at a later stage (when the lungs have already undergone damage and inflammation). Thus, a proper awareness about COPD is necessary. In this article, we will discuss some important points related to COPD to help people understand the condition better.

While there can be a plethora of triggers, two of the medical conditions that elevate the incidence of COPD are Chronic Bronchitis and Emphysema. The bronchial tubules functions as a carrier transporting the air (oxygenated and deoxygenated) from the lungs to the different body parts and vice versa. 

In case of Chronic Bronchitis, the lining of these tubules undergo severe inflammation. 
In the case of Emphysema, the inner walls of the alveoli may rupture resulting in deleterious consequences including breathlessness.
For long people were of the opinion that COPD only affects people who smoke. However, various surveys suggest that COPD does affect non-smokers as well. While smoking does make a person more susceptible to the condition (COPD as well as Chronic Bronchitis and Emphysema), other factors such as chronic and severe neonatal lung ailments or prolonged exposure to the harmful gases and lung irritants can also act as triggers.

Though the incidences of COPD are relatively higher in people above 45 years, the young adults or the middle-aged can also be affected. Also, COPD is not limited to males and can affect females as well. Some of the symptoms associated with COPD include chest tightness, wheezing, breathlessness, chronic cough (often with mucus). These symptoms are quite similar to those of Asthma with people often confusing between the conditions. Thus, a proper diagnosis is vital. Spirometry is a lung test used in the diagnosis of COPD. This test evaluates the functioning of the lungs by measuring the amount of air inhaled and exhaled.

When we talk about the treatment or management of COPD, quitting smoking does improve the condition. For people with breathing troubles and chronic cough, the Bronchodilators (can be long-acting or short-acting Bronchodilators depending on the extent of the discomfort) comes as a great relief. The use of corticosteroids (inhaled) can go a long way to alleviate the inflammation of the airways.

In extreme cases with reduced oxygen reaching the blood, a person may need Oxygen Therapy to improve the condition. Of late the Pulmonary rehabilitation program have been benefiting people in dealing with COPD better. The program involves an amalgamation of counselling sessions to educate the people about the diet and nutrition, precautions to be followed along with some healthy lifestyle changes.

COPD - Things You Must Always Remember!

Although your body is already in possession of the bacteria leading to tuberculosis, your immune system is able to prevent you from becoming sick. Doctors have made a distinction between latent and active tuberculosis (TB). In case of latent TB, the bacteria in the body in a passive state and it causes no symptoms, and therefore it is not contagious. But, in the case of active TB, you would become sick and may even spread the disease to others. It can take place in the first few weeks or even after several months of being infected with TB bacteria.

What are the symptoms of active TB?

If you are coughing for over three weeks and sometimes even coughing up blood, it can be a sign of TB. 
Chest pain and pain while coughing and breathing along with fatigue, fever, chills and night sweat are the common symptoms of TB along with loss of appetite and unintentional weight loss. TB may even affect other organs of your body, including your brain, spine and kidneys. 
When TB takes place outside the lungs, then the signs of TB can vary as per the organs that are involved. For instance, TB in the spine can cause back pain and that in kidneys may cause blood in the urine.
What are the causes of TB?
TB is caused by a bacteria which spreads from individual to individual via the microscopic droplets that are released into the air. This may happen when an affected person is left untreated and he speaks or sneezes or coughs or laughs. 

Though the disease is contagious, it is not easy to be affected by it. As a result, you are much more likely to get affected with active tuberculosis from a person you live with or come in regular contact with, rather than a stranger. It is important to note here that people who are affected with TB and going through proper medications for over two weeks are no more contagious.

Right from the 1980s, the number of individuals affected with TB has increased dramatically, owing to the spread of HIV, which is the virus known for causing AIDS. A person infected with HIV has a weak immunity system as a result of which it becomes difficult for the body to deal with TB bacteria. So those who have AIDS are more likely to be affected with active TB and sometimes the latent form also progresses to an active one very quickly. Therefore, it is important to seek medical assistance and detect if you have any such health complications concerning TB.

Tuberculosis - Watch Out For These Warning Signs!

Cancer like most other diseases has the best rates of recovery with early detection and intervention. As there are no regular health screenings for blood cancer, only the awareness about the early warning signs can save your life. November is designated as the Lung Cancer Awareness Month, to ensure every individual is equipped to fight against lung cancer right from the start. Here are 4 vital facts you must know to win your fight against blood cancer.
Lung cancer is also known as pulmonary carcinoma or cancer of the lung. It occurs when DNA mutations develop in the cells/ tissues of the lungs leading up to uncontrolled growth in the tissues of the lung. By far, it is known to be the most common cancer in Asia.

1. Type: lung cancers can present as one of the following types: 

Non-Small Cell Lung Cancer (NSCLC): Most common type of lung cancer and constitutes nearly 85% of all lung cancers. The sub-types of NSCLC are as follows:
Large cell carcinoma
Squamous cell carcinoma (SqCC) (Epidermoid)
Adenocarcinoma   accounts for majority of the NSCLC.
Small Cell Lung Cancer (SCLC): It is also known as oat meal cancer and tends to spread (metastasize) quickly. This constitutes about 15% of the lung cancers.
Mesothelioma: It is a rare cancer that develops in the mesothelial cells of the pleural or peritoneal surfaces. It usually arises in the pleural membrane lining the lungs, known as pleural mesothelioma. One that arises from the peritoneum is called the peritoneal mesothelioma and the one that arises from the pericardium is known as pericardial mesothelioma. Lastly, it can also arise from the tunica vaginalis known as testicular mesothelioma. People working with or prior exposure to asbestos are mostly at risk of developing mesothelioma. The latency period between time of exposure and development of mesothelioma can be somewhere between 20 to 40 years. Maximum of the patients who develop mesothelioma are men.
2. Gender: It affects the male populace predominantly. It is more common in men than in women and in those of lower economic status. However, the incidence of lung cancer, in women too, is on the rise of late.

3. Etiology: Cigarette/ Tobacco smoking remains the most important cause of lung cancer accounting for 85   90% of the cases. Incidence/ risk is proportionate to the number of cigarettes smoked irrespective of the age. Also, environmental toxins including smoke from burning black tar, exhaust gases from automobiles etc. too contribute actively to various lung diseases including cancer. People working in asbestos manufacturing factories who are exposed to asbestos dust are also likely to get lung cancer. Tuberculosis too is an additive risk factor. Again, people who have received ionizing radiation especially to treat Hodgkin Lymphoma or other malignancies also run the risk of developing lung cancer. Above-mentioned causes apart, genetic factors may also play a role.

4. Features: Lung cancer clinically presents in the following ways mainly. Signs & symptoms of malignant mesothelioma are as enumerated below

Difficult/ labored breathing (Dyspnea)
Chest pain
Palpable chest wall mass
Discordant chest wall expansion
Weight loss (Cachexia)
Loss of appetite (Anorexia)
Night sweats
Signs & symptoms of non-small cell lung cancer (NSCLC) are as enumerated below. Majority of patients are symptomatic at diagnosis

Chronic cough
Difficult/ labored breathing (Dyspnea)
Chest pain
Blood stained sputum (Hemoptysis)
Hoarseness
Weight loss (Cachexia)
Loss of appetite (Anorexia)
Weakness
Bone pain
Pleural or pericardial effusion
Superior vena cava syndrome
Brachial plexopathy
Neurologic pain
Hypercalcemia of malignancy
Signs & symptoms of small cell lung cancer (SCLC) are as enumerated below

Symptoms as per the points 8   18 depicted above for NSCLC are applicable for SCLC as well. Additionally, patients suffering from SCLC may have:

Fever associated with chest infections like bronchitis/ pneumonia that refuse to go away or keep coming back
Horner syndrome
Paraneoplastic syndromes including encephalitis/ sub-acute sensory neuropathy, hyponatremia, acromegaly, cancer associated retinopathy, ectopic corticotropic syndrome etc all.
5. Screening: is generally recommended for asymptomatic/ symptomatic populations as surveillance for high-risk individuals   who are either current or former smokers (quit smoking within the last 15 years) have at least a 30 pack-year smoking history and those who do not have any prior history of lung cancer. The goal of screening, as usual, is to be able to detect & diagnose lung cancer at an early stage which is potentially curable. It is mostly radiologic with a low dose helical computed tomography (CT) scan being more effective in detecting early-stage lung cancer than a chest radiograph can.

6. Diagnosis: Abnormal blood test results may be indicative of malignancy, but a follow-up imaging/ biopsy is always the gold standard for an accurate diagnosis. Following are the diagnostics employed mainly:

Blood: Hb may be low, TLC, ESR and polymorphs increased. Adenocarcinomas are likely to express thyroid transcription factor 1 (TTF-1) or carcinoembryonic antigen (CEA). On the other hand, mesotheliomas are likely to express Wilms Tumor -1 (WT-1) protein and Calretinin.
Imaging: Thoracoscopy, Bronchoscopy, X-Ray, CT Scan etc all. Positron Emission Tomography (PET) / CT scan and Magnetic Resonance Imaging (MRI) scan help detect metastasis if any.
Biopsy: It clinches the histologic diagnosis and the nature of the disease.
7. Treatment: Conventional treatment includes surgery, chemotherapy and radiotherapy as contextually appropriate. Simultaneously, an adjunctive or integrative naturopathic treatment with suitable complementary & alternative medicines (CAM) too can help improve clinical outcomes and facilitate recovery as would be feasible contextually.

8. Prognosis: Preventive measures, earlier diagnosis and right early treatment are key for effective therapeutic management & better prognosis. Like most other cancers, the chances of cure for early-stage lung cancer are more. The cure/ recovery chances are influenced by the grade, stage of cancer, recurrence and the patient s general health & vitality etc all. The primary determinant of prognosis in NSCLC is the stage at which the cancer is diagnosed. For non-metastatic cancers, however, it is the nodal status that determines the stage and hence the prognosis.

9. Prevention: Rightly said, prevention is always a better choice. Cigarette smoking is to be avoided by all means as it is the single major cause of lung cancer. Even exposure to cigarette smoke (passive or secondhand) is also an established cause of lung cancer and is known to increase the risk of lung cancer in non-smokers as well. Preventing exposure to secondhand smoke can be helpful in decreasing the incidence and mortality of primary lung cancers. Above-mentioned apart, other important risk factors such as exposure to ionizing radiation, environmental carcinogens like smoke from burning black tar, exhaust gases from automobiles, outdoor air pollution, and occupational exposure to asbestos, arsenic, beryllium, nickel, cadmium, chromium etc all too are known to increase the risk for lung cancer and mortality thereof. In fact, cigarette smoking is known to potentiate the effect and hence the lung cancer risk of many of the above-mentioned carcinogens, multi-fold, in smokers. Thus, either eliminating or reducing the exposure to the above-mentioned carcinogens can lead to a decrease in the risk of lung cancer and incidences thereof. Furthermore, randomized clinical trials indicate that high-intensity smokers (only) who take supplementation of beta-carotene have an increased risk/ incidence of lung cancer. Vitamin E supplementation, on the other hand, does not affect the risk of lung cancer as indicated by the trials. 

In case you have a concern or query you can always consult an expert & get answers to your questions!

Lung Cancer Awareness Month - Lung Cancer In Nutshell!

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