Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. These abnormal cells do not carry out the functions of normal lung cells and do not develop into healthy lung tissue. As they grow, the abnormal cells can form tumors and interfere with the functioning of the lung, which provides oxygen to the body via the blood.

Lung cancer is the most common cause of death due to cancer in both men and women throughout the world. According to the U.S. National Cancer Institute, approximately one out of every 14 men and women in the U.S. is diagnosed with cancer of the lung at some point in their lifetime. Lung cancer is predominantly a disease of the elderly; almost 70% of people diagnosed with lung cancer are over 65 years of age, while less than 3% of lung cancers occur in people under 45 years of age.

What Causes Lung Cancer?

The development of lung cancer is strongly associated with cigarette smoking, approximately 90% of lung cancers are attributable to use of tobacco. Pipe and cigar smoking can also cause lung cancer, but the risk is not as high as with cigarette smoking. Tobacco smoke contains more than 4,000 chemical compounds, many of which are cancer causing (carcinogens). Passive smoking, i.e. the inhalation of tobacco smoke by non-smokers who live or work with smokers, is also an established risk factor for the development of lung cancer.

Genetic susceptibility (i.e. family history) may play a role in the development of lung cancer. Other causes of lung cancer include air pollution (from vehicles, industry, and power generation) and inhalation of asbestos fibres (usually in the workplace).

Lung Cancer Symptoms

Early symptoms and signs of lung cancer

There may be no symptoms at the onset of the disease. When present, common symptoms of lung cancer may include:

Coughing: This includes a persistent cough that doesn't go away or changes to a chronic smoker's cough, such as more coughing or pain.
Coughing up blood: Coughing up blood or rust-colored sputum (spit or phlegm) should always be discussed with your doctor.
Breathing Difficulties: Shortness of breath, wheezing or noisy breathing (called stridor) may all be signs of lung cancer.
Loss of Appetite: Many cancers cause changes in appetite, which may lead to unintended weight loss.
Fatigue: It is common to feel weak or excessively tired.
Recurring infections: Recurring infections, like bronchitis or pneumonia, may be one of the signs of lung cancer.
Signs of advanced stages of lung cancer

Advanced stages of lung cancer are often characterized by the spread of cancer to distant sites in the body. This may affect the bones, liver or brain. As other parts of the body are affected, new lung cancer symptoms may develop, including:

Bone pain
Swelling of the face, arms or neck
Headaches, dizziness or limbs that become weak or numb
Jaundice
Lumps in the neck or collar-bone region
Treatment

Treatment for cancer involves a combination of surgery to remove cancer cells, chemotherapy and radiation therapy to kill cancer cells. Lung cancer is incurable unless complete surgical removal of the tumour cells can be achieved. Surgery is the most effective treatment for lung cancer, but only a few percentage of lung cancers are suitable for surgery i.e. Stage I and II NSCLC and cancer that has not spread beyond the lung.

Radiation therapy may be used for both NSCLC and SCLC and is a good option for people who are not suitable for surgery or who refuse surgery. Chemotherapy is used for both NSCLC and SCLC. Chemotherapy drugs may be given alone or in combination with surgery or radiation therapy. Chemotherapy is the treatment of first choice for SCLC since it has usually spread extensively in the body by the time it has been diagnosed.

Also used in the treatment of lung cancer are targeted therapies. These are drugs (gefitinib and erlotinib) or antibodies (cetuximab, bevacizumab) that block the growth and spread of cancer by interfering with specific molecules involved in tumor growth and progression. They are used in some patients with NSCLC that does not respond to standard chemotherapy.

Lung Cancer: Causes, Symptoms and Treatments

The chronic obstructive pulmonary disorder is a highly prevalent lung disease. People affected by COPD suffer from difficulty in breathing which can hamper regular life to a considerable extent. Though there is no particular cure available for this condition so far, it can be essentially managed with lifestyle changes and proper treatments. This first step in the process is to quit smoking.

Which medicines are available for treating COPD?
Doctors use various medications for treating the symptoms and complications of this disease. Drugs that fall under any of the categories mentioned below, coupled with therapy sessions would be recommended.

Bronchodilators: These medicines which tend to come in the form of an inhaler help in relaxing the muscles around the airways. It can assist in relieving coughing and shortness of breath making it easier to breathe. You may need a short-acting bronchodilator to provide quick relief and a long-acting bronchodilator to use on a regular basis.
Combination inhalers: For those patients whose condition is severe and experience frequent flare-ups, combination inhalers are used. As the name implies, it is a combination of steroids and beta-agonist employed in the short or long acting bronchodilator. Your doctor might recommend this depending on your condition.
Theophylline: This class of medicine is quite inexpensive which is commonly used in the treatment of COPD and asthma. It can improve breathing while preventing flare-ups. But the side effects of this medicine are many and may include fast heartbeat, headache, nausea, and even tremor. Hence, your doctor might advise this medication only if it suits you.
Can lung therapies help in treating COPD?
Doctors often use additional therapies for the treatment of moderate to severe COPD:

Pulmonary rehabilitation program: These programs include exercise training, education, nutrition therapies and counseling. The affected person needs to work with the professionals who can tailor the rehabilitation program for meeting their specific needs. This treatment can shorten the duration of hospitalization and increase one s ability to take part in daily activities.
Oxygen therapy: If there is a lack of oxygen in the blood, you would need additional oxygen to supplement it. There are several types of equipment available in the market that can deliver oxygen to the lungs. Some of these are lightweight and portable which you may carry with you while running errands.
Is there any surgery available in the treatment of COPD?
Surgery may be the only option for people who have a severe form of COPD and emphysema. Some of the most common surgical interventions include bullectomy, lung transplant, and lung volume reduction surgery. There are individual risks and complications in each of these cases, and therefore, it is very important to manage the symptoms to avoid the need for surgical operations.

Thus, with caution and care, COPD can be managed effectively, and you may lead a normal life.


COPD- How Can It Be Treated?

Radiotherapy is a kind of treatment that kills the cancer cells by using high energy beams. Specialists use radiotherapy to treat a wide range of lung cancer. For early stage lung cancer, the radiotherapy may get rid of the cancer totally. For the small cell lung cancer you may have radiotherapy only. Then again you may have it with another treatment, for example, chemotherapy or surgery.

For small cell lung cancer, radiotherapy is used with or after chemotherapy. Chemotherapy makes the tumor in the lung shrink. You may have radiotherapy to your cerebrum, which tackles any cancer cells that may have spread to the brain. This is called prophylactic cranial illumination (PCI). In case of advanced lung cancer, the treatment contracts the tumor and controls it for a while. It additionally decreases symptoms like shortness of breath.

The types of radiotherapy used for the lungs include:

Outer radiotherapy: This kind of radiotherapy comes from a machine and is administered to the body through an external source. It depends on the kind of cancer and the progression of the same. You may have three radiotherapy sittings every day for around 12 days. This sort of radiotherapy is known as CHART ceaseless hyperfractionated quickened radiotherapy. A few people with small cell lung cancer may have treatment twice a day. If you are getting radiotherapy to control the side effects of lung cancer, you may have a single treatment or day by day medications for up to 3 weeks.



Inner radiotherapy: This is called brachytherapy or endobronchial treatment. This will be administered during a bronchoscopy. The radiation is given through a thin tube that the specialist puts inside your aviation route for a few of minutes. Specialists use this sort of treatment to shrink a tumor that is blocking or pushing your breathing track and making breathing troublesome for you.

These are some of the procedures that take place while you are having lung cancer radiotherapy:

Radiotherapy machines are enormous. The machines are fixed in one position or are sometimes ready to go around your body to give treatment from various angles.
Prior to your first treatment, your radiographers will clarify what you will hear and see. The treatment room normally have docks for you to connect to music players. So you can listen to your own choice of music.
You cannot feel radiotherapy when you really have the treatment. It takes anything from one second to a few minutes. It is essential to lie similarly situated every time, so the radiographers may take a short time to get you prepared.
Once you are in the right position, the staff will allow you to sit in the space for a couple of minutes. They watch you constantly on a closed circuit TV screen. They may request that you hold your breath or take shallow breaths during the treatment.
In case you have a concern or query you can always consult an expert & get answers to your questions!

Radiotherapy For Lung Cancer!

It is no longer so surprising to read about alarming air pollution levels in our cities. On more than one occasion, these levels have risen above the danger levels. For some people, this may simply create an annoying fog that makes it difficult to see. For others, it can cause serious health issues. Air pollution is one of the most common reasons for the growing instances of asthma and allergies. Children are most susceptible to such diseases caused by air pollution.

Asthma and Allergies
Asthma can affect children even before their fifth birthday and the condition is characterized by breathlessness caused by a constriction of the airways. While the root cause of asthma is unknown, it is usually seen that asthmatic patients are more sensitive to others to particles in the air such as pollutants, dander, dust, smoke etc. Thus, the airways construct as a reaction to these allergens. Changes in the weather, a sudden cold draft or the flu can also aggravate asthma.

Can you Protect Your Children from Asthma?
Wheezing, panting, finding it difficult to breathe and a persistent cough are some of the signs of asthma. If you notice these symptoms, you must consult a doctor immediately. At home, here are a few things you could do.

Avoid exposing your children to smoke: Do not smoke around your children or allow others to smoke around them. If you cannot give up the habit, wear a smoking jacket when you smoke and take this off before you play with your children. When you ll go out, drive with the windows up so that your child does not inhale exhaust smoke. Set your air conditioner to circulate air within the car itself.
Dust often: Try and keep your home as dust free as possible. Use a wet cloth to clean so that the dust does not fly in the air. Wash all your bed linen once a week. Carpets and rugs should be vacuumed regularly or dusted outside. It may also be a good idea to invest in dust mite impermeable covers for your child s mattress and pillows.
Keep your Pets clean: If you share your home with pets, bathe them once a week and brush them daily. Do not let them climb on to the furniture or your beds. Also, avoid having their toys lie on your beds.
Wear a face mask: Try and time your child s outdoor activities when the pollution levels are low. Buy yourself and your child a face mask that will filter the air they breathe in. These should be worn whenever they play outdoors.
These simple steps could help your child be healthier and can prevent asthma and other such allergic reactions.

Increasing Asthma & Allergy In Children - What Should You Do?

Are you suffering from chronic bronchitis and are looking for ideal treatment measures? Bronchitis occurs when your windpipe or trachea and your large and small bronchitis within your lungs get inflamed because of infections and several other causes. The condition is considered to be chronic when your cough with mucus is persistent for at least three months. Chronic bronchitis is a condition that falls under the group of chronic obstructive pulmonary disease. Smoking, inhaled irritants, secondhand smoke, inhaled fumes, and certain viruses are primary causes of chronic bronchitis.

Symptoms
The symptoms and characteristics of chronic bronchitis are as follows:

Phlegm may be produced. The production of excess phlegm indicates that your lung and the lower respiratory tract are infected.
The cough experienced is present on almost all days of the month, for over a period of three months.
The forceful coughing because of chronic bronchitis is painful, and makes your abdominal and chest muscles sore. The coughing is likely to be very severe, and may injure your chest walls or make you faint.
During exacerbations of chronic bronchitis, wheezing may be experienced because of inflammation in the airways and muscular tightness. This, in turn, leads to shortness of breath.
Treatment
The treatment of chronic bronchitis depends on the cause. There is no specific cure for the condition, and its treatment aims at improving your lung function and reducing the symptoms.

Several medicines are used for managing the cough, and for loosening and clearing secretions. In the case of uncontrollable coughing spells, cough suppressants might be prescribed.
Broncho dilator inhalers are used for opening the airways and for the management of wheezing.
Certain nebulizer treatments are also recommended in some cases.
Corticosteroids are used for reducing the inflammation in the airways. These may be used in the form of inhaled corticosteroids, or may be taken orally.
In some cases, antibiotic medications may be required for the treatment of chronic bronchitis. Antibiotics are usually used when there is a bacterial infection, and in people with chronic lung problems, who require antibiotics to be treated.
Home oxygen might be required in extremely serious cases of chronic bronchitis.
In very rare cases, a patient may have to be hospitalized in case of severe breathing difficulty that does not respond to treatment. This is necessary in cases of complications in chronic bronchitis, and in patients who suffer from underlying heart problems.
It is recommended for you to consult a doctor on experiencing any symptom of chronic bronchitis. This will ensure proper diagnosis and an early start to your treatment, which will prevent worsening of the condition.

Chronic Bronchitis - 7 Tips To Help You Get Well!

Cancer like most other diseases has the best rates of recovery with early detection and intervention. As there are no regular health screenings for blood cancer, only the awareness about the early warning signs can save your life. November is designated as the Lung Cancer Awareness Month, to ensure every individual is equipped to fight against lung cancer right from the start. Here are 4 vital facts you must know to win your fight against blood cancer.
Lung cancer is also known as pulmonary carcinoma or cancer of the lung. It occurs when DNA mutations develop in the cells/ tissues of the lungs leading up to uncontrolled growth in the tissues of the lung. By far, it is known to be the most common cancer in Asia.

1. Type: lung cancers can present as one of the following types: 

Non-Small Cell Lung Cancer (NSCLC): Most common type of lung cancer and constitutes nearly 85% of all lung cancers. The sub-types of NSCLC are as follows:
Large cell carcinoma
Squamous cell carcinoma (SqCC) (Epidermoid)
Adenocarcinoma   accounts for majority of the NSCLC.
Small Cell Lung Cancer (SCLC): It is also known as oat meal cancer and tends to spread (metastasize) quickly. This constitutes about 15% of the lung cancers.
Mesothelioma: It is a rare cancer that develops in the mesothelial cells of the pleural or peritoneal surfaces. It usually arises in the pleural membrane lining the lungs, known as pleural mesothelioma. One that arises from the peritoneum is called the peritoneal mesothelioma and the one that arises from the pericardium is known as pericardial mesothelioma. Lastly, it can also arise from the tunica vaginalis known as testicular mesothelioma. People working with or prior exposure to asbestos are mostly at risk of developing mesothelioma. The latency period between time of exposure and development of mesothelioma can be somewhere between 20 to 40 years. Maximum of the patients who develop mesothelioma are men.
2. Gender: It affects the male populace predominantly. It is more common in men than in women and in those of lower economic status. However, the incidence of lung cancer, in women too, is on the rise of late.

3. Etiology: Cigarette/ Tobacco smoking remains the most important cause of lung cancer accounting for 85   90% of the cases. Incidence/ risk is proportionate to the number of cigarettes smoked irrespective of the age. Also, environmental toxins including smoke from burning black tar, exhaust gases from automobiles etc. too contribute actively to various lung diseases including cancer. People working in asbestos manufacturing factories who are exposed to asbestos dust are also likely to get lung cancer. Tuberculosis too is an additive risk factor. Again, people who have received ionizing radiation especially to treat Hodgkin Lymphoma or other malignancies also run the risk of developing lung cancer. Above-mentioned causes apart, genetic factors may also play a role.

4. Features: Lung cancer clinically presents in the following ways mainly. Signs & symptoms of malignant mesothelioma are as enumerated below

Difficult/ labored breathing (Dyspnea)
Chest pain
Palpable chest wall mass
Discordant chest wall expansion
Weight loss (Cachexia)
Loss of appetite (Anorexia)
Night sweats
Signs & symptoms of non-small cell lung cancer (NSCLC) are as enumerated below. Majority of patients are symptomatic at diagnosis

Chronic cough
Difficult/ labored breathing (Dyspnea)
Chest pain
Blood stained sputum (Hemoptysis)
Hoarseness
Weight loss (Cachexia)
Loss of appetite (Anorexia)
Weakness
Bone pain
Pleural or pericardial effusion
Superior vena cava syndrome
Brachial plexopathy
Neurologic pain
Hypercalcemia of malignancy
Signs & symptoms of small cell lung cancer (SCLC) are as enumerated below

Symptoms as per the points 8   18 depicted above for NSCLC are applicable for SCLC as well. Additionally, patients suffering from SCLC may have:

Fever associated with chest infections like bronchitis/ pneumonia that refuse to go away or keep coming back
Horner syndrome
Paraneoplastic syndromes including encephalitis/ sub-acute sensory neuropathy, hyponatremia, acromegaly, cancer associated retinopathy, ectopic corticotropic syndrome etc all.
5. Screening: is generally recommended for asymptomatic/ symptomatic populations as surveillance for high-risk individuals   who are either current or former smokers (quit smoking within the last 15 years) have at least a 30 pack-year smoking history and those who do not have any prior history of lung cancer. The goal of screening, as usual, is to be able to detect & diagnose lung cancer at an early stage which is potentially curable. It is mostly radiologic with a low dose helical computed tomography (CT) scan being more effective in detecting early-stage lung cancer than a chest radiograph can.

6. Diagnosis: Abnormal blood test results may be indicative of malignancy, but a follow-up imaging/ biopsy is always the gold standard for an accurate diagnosis. Following are the diagnostics employed mainly:

Blood: Hb may be low, TLC, ESR and polymorphs increased. Adenocarcinomas are likely to express thyroid transcription factor 1 (TTF-1) or carcinoembryonic antigen (CEA). On the other hand, mesotheliomas are likely to express Wilms Tumor -1 (WT-1) protein and Calretinin.
Imaging: Thoracoscopy, Bronchoscopy, X-Ray, CT Scan etc all. Positron Emission Tomography (PET) / CT scan and Magnetic Resonance Imaging (MRI) scan help detect metastasis if any.
Biopsy: It clinches the histologic diagnosis and the nature of the disease.
7. Treatment: Conventional treatment includes surgery, chemotherapy and radiotherapy as contextually appropriate. Simultaneously, an adjunctive or integrative naturopathic treatment with suitable complementary & alternative medicines (CAM) too can help improve clinical outcomes and facilitate recovery as would be feasible contextually.

8. Prognosis: Preventive measures, earlier diagnosis and right early treatment are key for effective therapeutic management & better prognosis. Like most other cancers, the chances of cure for early-stage lung cancer are more. The cure/ recovery chances are influenced by the grade, stage of cancer, recurrence and the patient s general health & vitality etc all. The primary determinant of prognosis in NSCLC is the stage at which the cancer is diagnosed. For non-metastatic cancers, however, it is the nodal status that determines the stage and hence the prognosis.

9. Prevention: Rightly said, prevention is always a better choice. Cigarette smoking is to be avoided by all means as it is the single major cause of lung cancer. Even exposure to cigarette smoke (passive or secondhand) is also an established cause of lung cancer and is known to increase the risk of lung cancer in non-smokers as well. Preventing exposure to secondhand smoke can be helpful in decreasing the incidence and mortality of primary lung cancers. Above-mentioned apart, other important risk factors such as exposure to ionizing radiation, environmental carcinogens like smoke from burning black tar, exhaust gases from automobiles, outdoor air pollution, and occupational exposure to asbestos, arsenic, beryllium, nickel, cadmium, chromium etc all too are known to increase the risk for lung cancer and mortality thereof. In fact, cigarette smoking is known to potentiate the effect and hence the lung cancer risk of many of the above-mentioned carcinogens, multi-fold, in smokers. Thus, either eliminating or reducing the exposure to the above-mentioned carcinogens can lead to a decrease in the risk of lung cancer and incidences thereof. Furthermore, randomized clinical trials indicate that high-intensity smokers (only) who take supplementation of beta-carotene have an increased risk/ incidence of lung cancer. Vitamin E supplementation, on the other hand, does not affect the risk of lung cancer as indicated by the trials. 

In case you have a concern or query you can always consult an expert & get answers to your questions!

Lung Cancer Awareness Month - Lung Cancer In Nutshell!

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