Why does PAIN occur? Understand the Mechanism of Pain

Pain is an unpleasant and distressing physical sensation caused by disease or injury, which induces hurt and anxiety in those suffering from it.
There are many different manifestations of pain, ranging from short term (acute pain) to long term (chronic pain). Other classifications include pain in the internal organs (visceral pain), injured tissue (inflammatory pain), nerves (neuropathic pain), etc.

The reason for the occurrence of pain depends on the cause and kind of pain being experienced. In most cases, pain acts as a warning sign that the body has been afflicted by a disorder of some sort, which may have arisen due to internal sickness or external wounding. Acute pains are generally cured on their own through rest or simple medication. Chronic pains, on the other hand, are more complicated in nature and the treatment requires more elaborate diagnosis.

The mechanism of pain

Pain is an extremely personal and subjective experience and affects each individual to varying degrees. The pain signals, which can arise in any part of the body, travel through the spinal cord to the brain along thousands of specialized nerves and nerve fibres. In the brain, it is processed in the centres associated with anxiety, emotions, memory, appetite, etc. Signals and pain inputs are then returned from the brain to the spinal cord, which may heighten or diminish pain.

In some cases, pain may also be induced by damage to the brain and spinal cord, which happens after a stroke.
A constant barrage of pain signals may cause the cells at the end of nerve fibres to become over-sensitized. This is known as 'wind-up' and is one of the most common causes of chronic pain that occurs even though the root of the problem has been identified and treated.

The causes and effects of pain differ from case to case depending on the signals received by the brain and its interpretation. It affects the individual's day to day activities and if persistent, can also have a harmful impact on mental health and psychosis. Pain is always handled, diagnosed and treated differently in all patients by drawing out the best possible solution to the problem.





Why does PAIN occur? Understand the Mechanism of Pain

The appendix is a small, finger-shaped pouch attached to the large intestine in the right belly area. It is a vestigial organ as it has no specific role to play in humans, but the organ is still seen, though in a very small size compared to the earlier living beings in the evolutionary chain. Acutely inflamed appendix is the most common cause leading to it removal, often seen in the ages of 10 to 19.

Causes: the appendix gets infected by two main reasons - general infection in the abdomen that reaches the appendix or blockage of the appendix leading to inflammation and swelling within it. The appendix is a blind pouch, and there is a good chance for its blockage from food particles, lymphatic tissue, or even sometimes feces. Some of the potential risk factors for appendicitis include a diet low in fiber, high in sugar, gut flora, and family history.

Symptoms/diagnosis: in adults, the appendicitis has very characteristic symptoms including acute pain in the right upper part of the belly associated with fever and vomiting. However, in children, the pain may not be as tell-tale a sign but is still quite diagnostic of appendicitis. However, presence of the following symptoms together is surely indicative of appendicitis.
1. Right abdominal pain, especially rebound tenderness, where pressure placed in the right upper part of the belly and released leads to excruciating pain.
2. Fever, nausea, and vomiting
3. Abdominal fullness or bloating
4. Elevated white blood count (as with most infections)
Additionally, the younger the child, the symptoms are not very clear, but ultrasound will confirm the diagnosis. The inflamed, enlarged appendix will be visible on the images and could be surrounded by free fluid. Ct scan also can be considered if required to confirm the diagnosis.

Treatment: as noted above, children present with symptoms that do not pinpoint to appendicitis. Treatment usually takes two routes:

If diagnosed as appendicitis before rupture, then surgical removal is the best method to contain its symptoms. Other symptoms like fever and nausea and vomiting usually subside a couple of days after the surgery.
If the appendicitis goes unnoticed and ruptures, then the intestinal cavity can get infected, which is called peritonitis. Earlier, the preferred approach was to control the infection and then go for removal. However, lately, removing the appendix followed by antibiotics to control the infection is the preferred approach.
The prognosis and recovery from appendicitis is very good. Deaths have occurred only in very small infants, where they are not able to pinpoint the area and therefore it can go undiagnosed, leading to rupture and subsequent death.

Early identification is the key to proper identification, immediate treatment, and complete recovery from appendicitis.

Appendicitis in Children

Abdomen pain or abdominal pain is usually experienced in the area between the chest and the stomach. This kind of pain usually comes as a dull cramp that also produces shooting stabs of pains intermittently, or it may be a localised pain in one side of the stomach. This may also be accompanied by inflammation, and other diseases related to organs like intestines, kidneys, pancreas, liver, spleen and stomach.

So what are the causes of stomach or abdomen pain? read on to find out:

1. Food poisoning: food poisoning can be caused due to dirty water or contaminated food. This can give rise to various infections as well as conditions like traveller's diarrhoea or loose motions.

2. Gastro intestinal conditions: gerd or gastroesophaegal reflux disease and gastroenteritis, among various others can also lead to abdomen pain as a symptom along with severe acidity and nausea. Irritable bowel syndrome is another major ailment which can leave you with persistent abdominal pain. 

3. Generalised pain: this kind of pain occurs in the overall area all around the stomach and may point at the presence of conditions like crohn's disease, a traumatic injury, appendicitis, flu, or even a urinary tract infection. Further, when the gas settles and tightens the stomach due to the inability to pass a motion on a normal, regular basis, this may be termed as constipation. This also leads to abdomen pain. 

4. Localised lower abdomen pain: pain that is found specifically in the lower area of the abdomen can be caused due to appendicitis, obstruction or blockage in the intestine or colon, and other ailments. This pain can also be accompanied by nausea and vomiting. 

5. Localised upper abdomen pain: this kind of pain may emanate due to the presence of gallstones, liver inflammation or hepatitis, pneumonia, or even in the middle of a heart attack.

6. Localised centre abdomen pain: pain in the centre part of the stomach or abdomen may be caused due to gastroenteritis, an injury or even the accumulation of waste products in the body, otherwise known as uraemia.

7. Abdomen pain and women: for women, such localised pain may be caused due to pelvic inflammatory disease, urinary tract infection, endometriosis, ectopic pregnancy, menstrual cramps which are also called dysmenorrhoea, and fibroids. Miscarriages can also cause pain in this part of the abdomen, for women.

8. Renal stones: renal stones or stone in kidney is one of the most common cause of abdomen pain. The pain caused by kidney stone is such that it can make a patient roll in bed and this pain may radiate to toward the groin as well.

Persistent pain and nausea that come with vomiting and finally give rise to blood in the vomit or stool should be checked by the doctor immediately, so as to rule out any serious ailment. Imaging tests, ultrasound and an x-ray can help in diagnosis.



Abdomen Pain: Common Causes

Knowingly or unknowingly, people often end up consuming food items that affect their digestive health negatively, instead of providing health benefits. Yes, the majority of people think that they can digest any kind of food and won't suffer from any side effects at all. But in reality, based on the preparation, processing, and ingredients present in them, some foods end up triggering digestive problems. 

Let's take a look at some such foods that can be bad for the digestive health.

Processed Foods: Processed or packed foods are high in carbohydrates, and can cause various digestive issues, such as bloating, cramping, gas formation, hypertension, and diabetes, when consumed in large amounts.
Alcohol: Technically speaking, alcohol may not be a food; but if you consume alcohol every time you eat, it can be counted as a food item. When the consumption of alcohol is moderate to high, it can cause acid reflux or heartburn, inflammation in the stomach lining, stomach cramps, and even diarrhea.
Artificial Sweeteners: Artificial sweeteners may work great for keeping your blood sugar in control but may affecctyour digestive system adversely. Artificial sweeteners contain ingredients that can increase the chance of bloating, gas, diarrhea, and inflammation.
Fried and Greasy Foods: Fried foods and greasy food are not only difficult to digest but they can also cause minor digestive problems, which later lead to intense stomach conditions such as acid reflux, heartburn, bloating, tummy upset, belching, etc.
Chocolates: Are you fond of eating chocolates? Having a sweet tooth can cost you your digestive health. From heartburn to an upset stomach, eating too many chocolates or candies can result in loose stools and diarrhea.
Foods Rich in Spice: Eating too much of spicy foods and those that contain chili peppers for a tangy flavor can often lead to heartburn and acidity. While you may enjoy eating something delicious with a tangy and spicy taste, the damage it may cause to your digestive health can be a cause forconcern.
Too Much of Caffeine: Drinking too much coffee or drinks with a high caffeine content cannot only irritate the stomach but also damage the smooth functioning of the digestive system. Heartburn, inflammation, constipation, and dehydration are some of the common digestive problems posed by coffee.
Raw Vegetables and Acidic Fruits: While consuming too many acidic fruits can cause acid reflux and stomach inflammation, eating raw vegetables leads to cramps, diarrhea, bloating and gas as they pass through the digestive system undigested.
For those who are concerned about their digestive health, consulting a doctor is recommended. In case you already have a stomach related ailment or disorder or have suffered from any in the past, a doctor can suggest and advice you and what are the best foods to incorporate in your diet.


Digestive Health - 8 Things You Should Just Say 'No' To!

From time to time each person tends to get dyspepsia which is basically a mild discomfort in the upper belly or abdomen. Dyspepsia which is also known as indigestion affects millions of people on a daily basis. It s mostly caused by over eating, eating greedily or worse conditions such as stomach ulcer, irritable bowel syndrome or gastrointestinal disease. 

Medically dyspepsia is defined as difficult digestion that is sometimes accompanied with symptoms such as vomiting, heartburn, nausea and bloating. A treatment plan for the patient is usually determined by what causes the indigestion. Below are some of the treatment options available to patients.
Antacids, h-2-receptor antagonists and ppls (proton pump inhibitors)

These three type of drugs all work to reduce the levels of acid in the stomach. Doctors tend to prescribe antacids as the first drug which are usually over the counter and require no prescription. In spite of antacids working fast, h-2-receptor antagonists tend to last longer. However, h-2-receptor antagonists tend to have side effects such as nausea and diarrhea. The other drug option is ppls which is very effective for patients with dyspepsia and also suffer from gastroesophageal reflux disease. 

They are stronger than h-2-receptor antagonists.

Prokinetics and antibiotics: This medication is usually prescribed to treat indigestion and works if the stomach empties slowly. Antibiotics on the other hand are used when indigestion is a result of peptic ulcers caused by Helicobacter pylori.
Antidepressants: There are a lot of factorsthat cause dyspepsia. However, if the doctors cannot find any cause of a patient s indigestion and no other drug has been effective, they tend to prescribe antidepressants. This medication is used to lessen the level of discomfort that comes with dyspepsia thereby reducing pain.
Home remedies: There are a few studies on natural remedies that can help treat dyspepsia. One of the remedies is to use baking soda to neutralize the stomach acid. This remedy is said to be more effective than antacids. Then there is ginger which while not mentioned to be effective in treating indigestion, helps in relieving nausea and has no side effects. Also peppermint has an effect on how the gastrointestinal tract works and helps with irritable bowel syndrome. However, it does not have a large effect on dyspepsia.
Diet and lifestyle changes: Indigestion is mostly caused by what we put into our bodies or eat and one way of treating it is by controlling our diet. This will especially work if you have mild symptoms that do not occur often. It s advisable to consume foods that are low or reduced in fat content and to, avoid or limit alcohol, chocolates and caffeine. You should also get enough sleep.
A healthy lifestyle goes a long way in helping to relieve indigestion.

Dyspepsia - 4 Best Ways It Can Be Treated!

Vulvodynia is a condition which causes severe pain in the opening (vulva) of the vagina without any apparent reason. The pain might be chronic in nature and can go on for years. Vulvodynia might affect your emotional health in the long-term and cause anxiety, depression and disrupted sleep patterns, if not treated immediately.

Doctors are still unsure regarding the exact causes of Vulvodynia. But there are few factors, which can increase your risks of suffering from this disorder:

    If you have a sensitive skin or have any past history of previous vaginal infections, you might be susceptible to vulvodynia.
    Vulvodynia might also be caused due to past injuries around the vulva.
    Sometimes, hormonal changes might also cause Vulvodynia.
    This disorder can also occur in women who have previously suffered from recurrent instances of sexual abuse.

The symptoms of Vulvodynia can be acute or chronic in nature with the pain being confined to one particular area or around the entire region.
The treatments for Vulvodynia aim at regulation of the symptoms. The most common treatments for Vulvodynia are:

    Your doctor might prescribe a specific dosage of steroids or antidepressants to get rid of the pain. Prescribed dosage of antihistamines might help to cure the itching sensation.
    You can apply a regulated amount of  Lidocaine  ointment around the vulvar regions thirty minutes before sexual intercourse.
    You can also opt for pelvic floor therapies as they might provide relief from significant pain in the pelvic floor muscles resulting from vulvodynia.
    If the pain is centralized around a particular area, you might opt for vestibulectomy to remove the affected tissues and get rid of the pain.

Can Sensitive Skin Be the Reason Behind Pain in the Opening of Vagina

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