Photodynamic therapy or PDT is a relatively new and non-invasive treatment for non melanomaskin cancer. It is mostly used in cases where the cancer is superficial and has not spread too deep. PDT is used mostly to treat Actinic Keratoses on the face and scalp, Basal cell carcinomas, Bowen s disease, as well as other conditions such as head and neck, mouth, lung and gullet cancer.

How does it work?
This treatment involves the use of a drug known as photosensitize or a photosensitizing agent with a specific type of light. When the photosensitizing agents get exposed to a light of a specific wavelength, a form of oxygen is produced, which eliminates nearby cancer cells. Every photosensitizer gets activated by the special light. The wavelength of the light determines how much it can penetrate into the body.

Process of Photodynamic therapy
Skin cancer is cured by PDT in several steps. The first step involves the injection of a photosensitizer into the patient s bloodstream. The blood cells absorb the agent all over the body, but in the cancer cells, it stays for a longer duration. Within 72 hours after the injection is given, the skin is exposed to light. The photosensitizer agent present in the cancer affected cells absorbs the light. An active oxygen form gets produced, which kills the cancer cells.

Other than killing the cancer cells directly, PDT uses two other ways to destroy cancerous tumors. The blood vessels in the tumor are affected, which leads to its death. The immune system also gets charged up and activated for fighting the cancer cells.

The light used for PDT is usually in the form of a laser. LEDs are also used to treat tumors present on the surface of the skin. The primary photosensitizing agent used in PDT is called porfimer sodium or Photofrin.

PDT can be undertaken in the outpatient department in a hospital. After taking the treatment, you have to keep the cancer affected area of the skin dry and covered for 36 hours. The area should be treated with care while showering. In case of thick skin lesions, repeat treatments are required within 4 weeks.

When is PDT used for skin cancer
PDT can be undertaken instead of surgery for treating basal cell cancer, Bowen s disease and actinic keratosis. PDT is used in cases where surgeries are required. It is used to treat large skin cancers, which are not very deep and in the case when several cancers develop in an area. For many skin conditions, PDT is a better remedy than undergoing a surgery.

Advantages of PDT

    There are no long term side effects.
    The process is less invasive compared to surgery.
    A very short time is taken for this therapy to be undertaken.
    The process can be repeated several times in the same area.
    Very less scarring takes place in the affected area.
    The cost of this procedure is lesser than surgery.

Treating Skin Cancer with Photodynamic Therapy

Skin cancer occurs when the DNA of the cells undergo mutations, thus causing unsystematic cell growth which evolve into a cancerous mass. This abnormality stems from the over-exposure of your skin to the Ultraviolet Radiations of the sun. 

However, there are other factors too that escalate the risks of skin cancer.

Fairer skin tone: Inadequate pigmentation or melanin content in the skin offers less protection against the harmful UV radiations. Having red or blond hair or light-colored eyes makes you more vulnerable to this condition.
Sunburns: A history of sunburns can often be the root cause behind skin cancer.
Excessive exposure to the sun: If you spend a considerable amount of time under the sun and especially if your skin is not protected by clothing or sunscreen, you tend to get a tan. A tan is the skin s response to extreme UV radiations.
Moles: Abnormally large moles, known as dysplastic nevi, are more likely to turn malignant. Watch out for any change in the texture of the moles, which is one of the most important symptoms of skin cancer.
Family history: According to studies, genes are considered to be one of the causes behind skin cancer. Hence, a family history of this condition could spell trouble for one.
Personal history: Having suffered from skin cancer previously in life could endanger one even more.
Pre-cancerous skin injury: Skin lesions, also known as actinic keratosis, make you prone to developing pre-cancerous growths on the skin. These could appear as scaly rough patches, ranging from brown to pink in color. They usually crop up on the hands, head and faces of people who are comparatively of a fairer skin tone.
A weak immune system: People having a poor immunity system, including the ones affected by HIV/AIDS or are on immunosuppressant drugs which follow any organ transplantation have greater risks of developing cancer.
Exposure to radiation: Radiation therapy is an often used treatment method for treating various skin conditions such as acne and eczema. Having been exposed to radiations, one could be indisposed to this condition even more.
Exposure to certain chemicals: Exposure to certain substances such as arsenic might increase your vulnerability manifold.

Skin Cancer - 10 Things That Can Increase Your Risk!

Melanoma is a condition which mainly indicates a severe malfunction of the melanocytes or the melanin producing cells of the body. These cells are responsible for giving you your skin colour, tone and complexion. Usually, a person suffering from melanoma will have many normal and irregular moles as well as melanoma in the eye and digestive tracts too.

Some general facts on melanoma are mentioned below:
Melanoma is common in young women and causes many deaths.
More than one million new instances of skin cancer or melanoma are analyzed every year.
There has been a 2000% increase in rate of melanoma since the year 1930. One out of fifty get affected by this cancer.
There has been a high rise in the rate of melanoma from 1970 to 2008. There has been an 800% increase in young women and 400% increase in case of similar aged men.
Early recognition makes melanoma treatable. It is screened for growth very minimally.
Primary causes Melanoma may be caused primarily due to these causes:
The most primary cause of melanoma is ultraviolet light (UV) in people with a low level of skin pigment. The UV light might be from either the sun or from different sources, for example, tanning devices. Around 25% of cases occur from or in the form of moles.
The individuals who work on airplanes seem to have an expanded danger, due to more contact with UV rays.
Ultraviolet UV light of wavelengths between 315 - 280 nm from the sun react with the skin cell DNA and result in a kind of direct DNA harm called cyclobutane pyrimidine dimers (CPDs).
In order to stay away or avoid melanoma, you should:
Avoid the sun at peak hours.
Examine your skin at times for some kind of change.
Keep away from tanning salons.Melanoma is a dangerous form of cancer and causes a lot of deaths. You should stay away from anything that causes melanoma.


All About Melanoma

Does Viagra add to the risks of melanoma?

Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). This form of skin cancer is mostly caused by exposure to ultraviolet radiations or it may be congenital in nature.

The cancer is easily detected by the naked eye and in 99% cases, the disease can be efficiently treated if detected during its early stages. Women below the 40 year age benchmark have a higher risk of cancer.

Viagra is a health supplement which is consumed in the oral form to minimize all the signs and symptoms of an erectile dysfunction. Viagra is the generic name for Sildenafil, which is used by men.

What does research say?

A medical study has shown that men who frequently use erection-enhancing drugs are 84% more likely to develop melanoma within a period of 10 years. This does not mean that you are bound to get this cancer if you are frequently using an erection enhancing drugs, but it might increase your probability of getting Melanoma.

Risk Factors

Viagra when combined with some other medicine often leads to adverse effects which might lead to cancer as well. It is always desirable that you consult your doctor before taking a Viagra in general. Some of the dangerous factors are:

1 Taking Viagra with nitrate drugs such as nitroglycerin, isosorbide mononitrate, and such others.
2 If you are experiencing an unreasonably high or low blood pressure
3 If you have any kind of a liver disease
4 If you are suffering from a kidney disease that requires dialysis (blood purification process)

Precautions

While taking Viagra, you should always consult a doctor near you. Additionally, you should also follow certain precautionary measures like:

  1. You should avoid buying Viagra online, as there is a high probability that it is fake
 2. You should try going for natural alternatives to Viagra. Studies have shown that the medicines with nitric oxide can help you in having a proper and enhanced erection. Additionally, medicines containing L-arginine are also very popular as they help in generating nitric oxide.



Does Viagra add to the risks of melanoma?

International Childhood Cancer Day is celebrated annually on 15 February to raise awareness and to express support for children and adolescents with cancer, survivors and their families.
We live in an age where every single individual, more or less, is exposed to the risk of cancer. It is probably an unfavorable lifestyle we lead that deprives us of good health. This might alarm many but considerable changes in lifestyle can help you realize cancer as a preventable disease. Cancer does not only make you undergo severe suffering but it also affects your friends and family. The pallor of misery spreads wider than you think.

A balanced and nutritious diet: Deciding on a plant- based diet or a Mediterranean diet can aid your fight against the risk of cancer. A Mediterranean diet will involve green leafy vegetables, lots of fresh fruits, whole grains, mixed nuts, legumes and also the use of extra- virgin olive oil. Fish can be a safe bet but red meat should be avoided. One must also try to avoid processed meat as they tend to make you prone to the risk of cancer.
Immunization: Hepatitis B and HPV or Human papilloma virus vaccines are extremely necessary to protect you against the every types of cancer.
Sun protection: Caring for your skin doesn't arise from vanity. Skin cancer is one of the most prevalent kinds of cancer; the chances of this disease can be restricted by remaining in shade especially during midday, by wearing covered clothes and by using a good sunscreen lotion repeatedly while outside.
Exercise diligently: Did you think it was okay to have weaker muscles and bulging layers of fat? If yes, you probably have grown numb to the inadequacies you face in result. Unchecked fat can lead to obesity which further complicates health conditions. Metabolic activity differs from person to person. Regular exercising can help regulate metabolism according to the needs of your body. Physical exercise protects you against the risk of breast and colon cancer. Moderate or vigorous physical activity for 150 to 75 minutes a week respectively can reduce the risk of cancer.

International Childhood Cancer Day - Few Tips to Reduce the Risk of Cancer

International Childhood Cancer Day is celebrated annually on 15 February to raise awareness and to express support for children and adolescents with cancer, survivors and their families.

Why is Cancer the biggest Threat to the YOUNG in India?

There are fewer Indians who have successfully battled Cancer and have emerged successful. Yuvraj Singh, the legendary cricketer, who was diagnosed with a rare cancer at 29, survived due to an early detection. Cancer cases in India are not as many as they are in the developed world. However, due to late detection the survival rate in the country is far worse. Particularly, we are losing our youth to Cancer. Most tobacco (pan masala) related cancers and child cancers go undetected until very late.

Few cancers like cervical cancer and breast cancer which affect women of any age, are curable, however, due to lack of awareness and timely screening, many Indian women succumb to these cancers. The most common sites for cancer among men are lung, prostate, colon, rectum, stomach and liver while that among women are breast, colon, rectum, lung, cervix and stomach.

In proportion to our population, we lack the right infrastructure nationwide. esp in the northern and north eastern region, there is a dearth of good cancer facilities, where radiation, care or treatment can be given. Not even one third of cancer patients are alive beyond 5 years after their diagnosis in India, and about 71% of cancer deaths occur in patients in their prime productive years   between the ages of 30 to 69 years.

 Most Indians believe that cancer is generally incurable and that it should be kept secret from neighbors and family.  -  Dr Paul Goss, MD, Harvard University.

All these factors have contributed to a very high mortality rate. No wonder Cancer is dreaded in the country. Investment, infrastructure, lifestyles as well as mindsets need to change if we were to contain the Cancer mortality rate. While you need to watch out for early signs of cancer, here are the lifestyle changes every individual esp. all youth must adopt to avoid cancer.

Avoid Tobacco - both smoking and chewing.

Reduce alcohol intake - Save your organs from deteriorating.

Limit UV ray exposure from the sun - Keeps your skin safe.

Maintain a healthy diet - Include foods rich in Vitamins, minerals and fiber which nourish your body and build immunity.

Increase your level of fitness - Maintain a good bodyweight. Additional flab invites a host of troubles, that includes variety of cancers.

Seeking regular medical checkup or screening - This is the only way to prevent and get detected early on.

International Childhood Cancer Day - Why Cancer Is A Threat For Young?

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