Did you know that Thalassemia is a common blood disorder in India, that?s passed through families (just the way it was passed to Abhishek Bachchan because megastar Amitabh Bachchan is a carrier). It is characterized by excessive destruction of red blood cells or genetic mutation, leading to anaemia. Today is World Thalassemia Day, lets understand about the disease.

Thalassemia can be classified into alpha and beta, depending on the globin genes that are affected.

1. Thalassemia Minor - Usually doesn?t have any symptoms, except for minor anaemia.

2. Beta Thalassemia - Has two serious types.

2.A) Thalassemia Major: This type usually happens before a child?s second birthday and requires regular blood transfusions. The condition is life-threatening. Symptoms include anaemia, fussiness, frequent infections, paleness of the skin, poor appetite, enlarged organs and jaundice.

2.B) Thalassemia Intermedia: It is a less severe form and doesn?t require blood transfusions. The symptoms include anemia, jaundice, extremely large spleen and malnourishment.

3. Alpha Thalassemia: Only in rare cases this severe form of Thalassemia may be present. Known as Hydrops Fetalis, this condition usually occurs before birth and children are either stillborn or die soon afterwards.

How to live with Thalassemia:

Take steps to be as healthy as possible. Follow a balanced diet eating plan as per the recommendation of your doctor. Take iron supplement only if prescribed. It is recommended that patients get themselves vaccinated whenever needed, especially if their spleen has been removed. Meanwhile, always be on a lookout for the signs of infections (such as fever) and lower your risk of infections. Thalassemia can spark fear, anxiety, depression and stress. That?s why, doctors recommend that patients receive adequate emotional support.

Treatment:

The treatments depend on the kind of Thalassemia an individual has. Usually, treatment procedures include blood transfusions, bone marrow transplants, removal of spleen or gallbladder specific medications and supplements.

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Read Dr. Jatin Soni's Health Tip on The Occasion of World Thalassemia Day

A healthy kidney produces a hormone known as the erythropoietin. The latter assists the bone marrow to produce an adequate amount of RBC that carries oxygen to every nook and corner of the body. A damaged kidney results in less RBC production, thereby, creating a condition known as anemia. The hemoglobin count in the blood reduces significantly in this condition.

Anemia is characterized by shortness of breath, weakness and tiredness. It can affect sleep and a loss of appetite. A patient suffering from anemia reports of frequent headaches and a faster heart rate. These symptoms also surface when a person suffers from chronic kidney diseases (CKD). The condition gets worse as the disease progresses.

Treating anemia:
A patient suffering from anemia should be treated on time as there are many pitfalls of a lower hemoglobin level. The treatment will give instant relief from other symptoms that might have arrived with CKD. Doctors frequently prescribe Erythropoiesis Stimulating Agent (ESA) for patients suffering from CKD and suffering from anemia due to the shortage of erythropoietin. ESAs can be injected through an injection or intravenously. These injections stimulate the bone marrow to produce more RBCs. However, studies have revealed that ESAs increase the chance of strokes, heart attacks and blood clots. Furthermore, they aggravate tumor growth and shorten life expectancy for cancer patients. People undergoing ESA treatment should have periodic check-ups to ensure that the hemoglobin count is normal and under control.

Iron
Iron count in the body has an important role in treating patients suffering from anemia and CKD. In case the level of iron is too low in the body, ESAs fail to improve the condition of an anemic patient. The ferritin count of a patient should be in the range of 100-800 mcg/L. One more test known as TSAT reveals the number of iron required to produce RBCs in the body. In case the iron count is less, doctors often suggest iron pills to bring the count to a more accepted level.

Other causes
There could be other reasons for anemia as well. A doctor might further investigate the level of B12 and folic acid present in the body. Even an inflammatory condition can lead to anemia. A decreased count of any of the above-mentioned ingredients can cause anemia to a patient suffering from EKD.

Food items necessary to improve the condition
A healthy diet helps in improving the condition of an anemic patient. Iron deficiency is best addressed by fish and beef. Food rich in vitamin C helps the body to absorb more iron in the body. Certain food items that block the entry of iron in the body include tea, milk, albumen (egg white) etc. Therefore, you should be strictly avoid these items from your diet.

Kidney Disease - How It Is Related With Anaemia?

Anemia is a condition where the red blood cell count is reduced due to deficiencies within the system. This is usually caused by a lack of iron, folate and other related nutrients in the diet. Anemia is a major public health concern in India as over 50 percent of women are known to be anemic. This pushes up the mortality rate of young mothers and even children.

Some symptoms of Iron deficiency anemia
Anemia has a wide range of symptoms which varies from person to person. However there are some generic symptoms which can be noticed in most people. Some of these are
1. Pale appearance of skin - Many people exhibit this symptom where their skin appears to be pale as there is a reduced amount of oxy - hemoglobin in the skin.
2. Physical weakness, light headedness and fatigue - This is a general symptom, which many tend to suffer from and complain about. Fatigue and weakness may come in very quickly even with the slightest effort.
3. Hair loss - Many women may complain about hair loss due to Iron deficiency  anemia.

Some other symptoms are -
a. Breathlessness
b. Constipation
c. Missed or irregular periods
d. Numbness or burning sensations
e. Depression
f. Tinnitus among others

Causes of Iron deficiency anemia
The primary cause of Iron deficiency anemia is the lack of iron in the diet which causes the hemoglobin in the blood to be reduced. Some of the patients may still have Iron deficiencyanemia as they have developed gastrointestinal disorders which prevents the absorption of nutrients like iron within the body.

How to treat Iron deficiency anemia
Diet related anemia can be easily cured or controlled with changing diets. Inclusion of certain foods within the diet can easily reverse the Iron deficiencies. Some of the food items that help with deficiencies are:
1. Fortified cereals
2. Green dark leafy vegetables
3. Poultry items
4. Eggs
5. Meat
You may also require certain iron supplements if you have certain underlying conditions which is causing issues with iron absorption.

How to prevent Iron deficiency anemia
It is important, especially for women to go for regular checkups to your doctor and also a hemoglobin check up. Your doctor or dietician can tell you to include certain foods in your diet that include folate, iron and vitamin B 12 so that the level of hemoglobin in your blood can be maintained at healthy levels.

All About Iron Deficiency - Anemia

Iron deficiency is most common among people of all age groups. The nutrient is critical, because it not just produces haemoglobin, it also protects red cells by providing them enough oxygen. Check out these symptoms to know if you are iron deficient.

1) Exhaustion- Do you feel tired, exhausted all the time? Most women think that it?s because of their frantic life. But it could actually be because your tissues don?t get enough oxygen.

2) Heavy Periods- Heavier blood flow is one of the reasons behind iron deficiency. Women may loose too much of blood and might not be able to replace it faster. Periods should only fill two to three tablespoons each month.

3) Paleness- Have people been telling you that you look pale or sickly. Low levels of protein and iron can suck away colour from your skin. 

4) Shortness of Breath- A flight of stairs seem like a mammoth of a task when you have less iron. If you easily get short of breath, it?s time you consult your doctor.

If you have any of the above symptoms or have more questions on this topic, click on consult privately to ask me.

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Iron Deficiency Is More Dangerous Than You Think. Symptom Checker Inside.

Anemia is a disease which occurs due to the lack of red blood cells or hemoglobin in your body. The body transports oxygen and the nutrition you get from food, to various body parts through hemoglobin, and a deficiency can cause lower supply of these important elements to the body. Which is why, the patient may feel a lack of energy, dizziness and even exhaustion. Most people don't realize its existence, so it's important that you know the symptoms, causes and cures of this blood disease. And, the foods one should eat to avoid anemia.

Lack of iron: There are various forms of this illness, and one of it is iron deficiency anemia. The red blood cells in the blood contain hemoglobin, which requires iron for formation. If the diet is not adequately loaded with iron, the person can have iron deficiency anemia. This is the most ordinary one that occurs to people, but with adequate care through food, exercise, and medicines, you can tackle it.
The root cause: Faulty production of red cells (hereditary conditions like sickle cell anemia, bone marrow disorders, etc. is the common cause of anemia. Excessive destruction of red blood cells, which is not compensated by normal production (spleen disorders, thalassemia, etc.) can be another reason. People with blood loss conditions (ulcers, gastritis, internal bleeding, excessive menstruation, childbirth, etc. and the ones who consume a poor diet can also get this blood disease.
Know the symptoms: There are essentially nonspecific symptoms of anemia, but overall fatigue with very low energy levels as the body does not receive enough nutrition to perform various functions can be one of them. Reduced heart rate, fainting, and pallor of skin and whites of the eye are common indicators of this illness. Check with your doctor if you face any of these issues.
Foods for prevention: If you follow a healthy diet that is full of nutrients like iron, you can keep anemia at bay. Remember, weight is not an issue here. If you have a good diet intake, you need not worry about being slim. Often, women who are thin get labeled as anemic, which is far from truth. When it comes to nutrients, iron-rich foods should be eaten along with vitamin C to improve its absorption. Vitamin B12 also plays a significant role in absorption. Meat including red meat, lamb, pork, chicken, beet, ham, turkey, and seafood including salmon or tuna can be included in your diet. Other foods like legumes, soybeans, veggies (dark green leafy vegetables, spinach, peas, broccoli), dried fruits and nuts, tofu, pumpkin and eggs are rich sources of iron that can be consumed by vegetarians. Cereals like red rice, brown rice or fortified cereals with a good source of iron can also be included in the diet.
Don't miss out on iron, ladies! Women are likely to be anemic (with symptoms like fatigue and paleness) and hence they should constantly monitor for iron levels and shift to a diet rich in iron. Furthermore, iron supplements can be consumed in the form of tablets, syrup, or tablets with the guidance of a doctor. In severe cases, where there is a significant blood loss, especially with childbirth or internal bleeding, the sufferer may require transfusion. All in all, anemia is definitely manageable with planning of diet, especially during times the like menstruation and pregnancy. So, taking care on time is a vital step.

Anemia - What Diet Should You Follow?

World Sickle Cell Day is observed each year on June 19th to raise the public awareness regarding this disease and its treatment methods. Sickle Cell disease is an inherited transmitted deformity/abnormality of haemoglobin. It is an inherited form of anaemia. This abnormality generates changes in the shape of red blood cells from round to crescent, which reduces the oxygen carrying capacity and slows down the flow of blood to various parts of the body. 

Generally, red blood vessels are round and flexible, passing easily through the blood vessels. The red blood cells become sticky and rigid in sickle cell anaemia. Sickle cells last 10 to 20 days, which causes anaemia because of the disorder of red blood cells, while healthy red blood cells could live up to 120 days.

Millions of people around the world are affected by Sickle Cell Anemia. There is no specific cure for this disease as Sickle cell anaemia is not contagious, it is hereditary. Sickle cell anaemia is named so for the reason that red blood cells are crescent-shaped or sickle-shaped, and anaemia signifies lack of blood. There is a difference between iron-deficiency anaemia and sickle cell anaemia.

Symptoms

Sickle Cell Disease (SCD) has many symptoms which includes: serious anemia, episodes of suffering, additionally a range of complications, heart failure, dizziness, chronic kidney disease (CKD), acute chest syndrome (ACS), chest pain, gallstones, pulmonary hypertension, immune deficiency, paralysis or stroke, splenomegaly, joint damage mainly in the hip joint, foot ulcers, delayed puberty, retinopathy, and endocrine disorders.

Diagnosis

Sickle Cell Disease is diagnosed by blood tests.

Treatment

Bone marrow transplant or stem cell transplant in patients usually below the age of sixteen is the only available cure for the disease.

Aim of the World Sickle Cell Day

The aim of the World Sickle Cell Day is to support and promote research for the patients in order to help them upgrade their overall quality of life to the maximum possible extent. It also aspires to increase awareness for sickle cell disease disorder in the general public so that they know how to deal with patients suffering from the disease. Moreover, the World Sickle Cell Day has the objective of raising awareness of the importance among generations of pre-marital screening to lessen the transmission of Sickle Cell Disease.

Target Groups for Awareness Programs

Though it is desirable that everybody knows about Sickle Cell Disease, the target groups for the awareness programs include health decision-makers, sickle cell anaemia sufferers and their families, health organizations and associations, people who are planning to get married, and the health workers including health educators, physicians, and nurses.

On the World Sickle Cell Day, different societies provide advocacy, information, and advice for raising awareness. They also provide educational and welfare grants, support services, annual children s holiday, home help, hospital visits, mentoring and befriending through holding talks, assisting into research and training, lobbying for better service provision, patient education seminars, and campaigning.

World Sickle Cell Day - What Should You Know?

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