Did you know that Thalassemia is a common blood disorder in India, that?s passed through families (just the way it was passed to Abhishek Bachchan because megastar Amitabh Bachchan is a carrier). It is characterized by excessive destruction of red blood cells or genetic mutation, leading to anaemia. Today is World Thalassemia Day, lets understand about the disease.

Thalassemia can be classified into alpha and beta, depending on the globin genes that are affected.

1. Thalassemia Minor - Usually doesn?t have any symptoms, except for minor anaemia.

2. Beta Thalassemia - Has two serious types.

2.A) Thalassemia Major: This type usually happens before a child?s second birthday and requires regular blood transfusions. The condition is life-threatening. Symptoms include anaemia, fussiness, frequent infections, paleness of the skin, poor appetite, enlarged organs and jaundice.

2.B) Thalassemia Intermedia: It is a less severe form and doesn?t require blood transfusions. The symptoms include anemia, jaundice, extremely large spleen and malnourishment.

3. Alpha Thalassemia: Only in rare cases this severe form of Thalassemia may be present. Known as Hydrops Fetalis, this condition usually occurs before birth and children are either stillborn or die soon afterwards.

How to live with Thalassemia:

Take steps to be as healthy as possible. Follow a balanced diet eating plan as per the recommendation of your doctor. Take iron supplement only if prescribed. It is recommended that patients get themselves vaccinated whenever needed, especially if their spleen has been removed. Meanwhile, always be on a lookout for the signs of infections (such as fever) and lower your risk of infections. Thalassemia can spark fear, anxiety, depression and stress. That?s why, doctors recommend that patients receive adequate emotional support.

Treatment:

The treatments depend on the kind of Thalassemia an individual has. Usually, treatment procedures include blood transfusions, bone marrow transplants, removal of spleen or gallbladder specific medications and supplements.

If you have any more questions on this topic, click on consult privately to ask me.

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Read Dr. Jatin Soni's Health Tip on The Occasion of World Thalassemia Day

Anemia is a medical condition in which the red blood cell count or hemoglobin is less than normal. Haemoglobin is the main part of red blood cells and it binds oxygen. If you have few or abnormal red blood cells, or your hemoglobin is low, the cells in your body will not get enough oxygen. Anemia can last temporarily or for a long-term, and it can range from mild to severe. If you suspect you have anemia, see your doctor immediately because it can be a warning sign of a serious illness. A person who has anemia is called anemic.

Sign and symptoms of anemia: Because a low blood cell count decreases oxygen delivery to every tissue in the body, anemia can cause a variety of signs and symptoms. It can also worsen the state of any other underlying medical condition. If anemia is mild, it may not cause any symptoms. If anemia is chronic, the body may adapt and compensate for the change. In this case, there may not be any symptoms until anemia becomes more severe. Anemia signs and symptoms may vary depending on the cause of the condition. These may include fatigue, weakness, pale or yellowish skin, irregular heartbeats, breathlessness, dizziness, chest pain, cold hands and feet, and headache.

Causes of anemia: Anemia occurs when your body doesn t have enough red blood cells. This can happen if: 

Your body doesn t make enough red blood cells: The bone marrow is essential for the creation of red blood cells. A number of diseases can affect the bone marrow, including leukemia, where too many abnormal white blood cells are produced. This disrupts normal production of red blood cells.
Bleeding causes you to lose red blood cells more quickly than they can be replaced: Iron deficient anemia is the most common type of anemia which often falls into this category. It is caused by a shortage of iron, which most often results due to blood loss. Blood loss can be acute and rapid or chronic. Rapid blood loss can happen at the time of surgery, childbirth, trauma, or a ruptured blood vessel. 
Your body destroys red blood cells: Red blood cells have a lifespan of 120 days in the bloodstream but they can be destroyed or removed beforehand. In one type of anemia, the body s immune system mistakenly identifies its own red blood cells as a foreign substance and attacks them. Excessive red blood cell breakdown can also occur due to infections, the use of certain drugs, snake or spider venom, severe hypertension, and in the case of clotting disorders.
Treatment of anemia: The treatment of anemia varies greatly. First, the underlying cause of anemia needs to be identified and corrected. Most of the times, iron supplements will be needed to correct iron deficiency. In severe anemia, blood transfusions may be necessary. Vitamin B12 injections are necessary in some cases who are suffering from a specific type of anemia.

Prevention of anemia: Many types of anemia can t be prevented. But iron deficient anemia and vitamin deficient anemia can be avoided by having a diet that includes a variety of vitamins and nutrients, including iron, folate, vitamin B12, and vitamin C.

Anemia - What Causes It?

Anemia is a disease which occurs due to the lack of red blood cells or hemoglobin in your body. The body transports oxygen and the nutrition you get from food, to various body parts through hemoglobin, and a deficiency can cause lower supply of these important elements to the body. Which is why, the patient may feel a lack of energy, dizziness and even exhaustion. Most people don't realize its existence, so it's important that you know the symptoms, causes and cures of this blood disease. And, the foods one should eat to avoid anemia.

Lack of iron: There are various forms of this illness, and one of it is iron deficiency anemia. The red blood cells in the blood contain hemoglobin, which requires iron for formation. If the diet is not adequately loaded with iron, the person can have iron deficiency anemia. This is the most ordinary one that occurs to people, but with adequate care through food, exercise, and medicines, you can tackle it.
The root cause: Faulty production of red cells (hereditary conditions like sickle cell anemia, bone marrow disorders, etc. is the common cause of anemia. Excessive destruction of red blood cells, which is not compensated by normal production (spleen disorders, thalassemia, etc.) can be another reason. People with blood loss conditions (ulcers, gastritis, internal bleeding, excessive menstruation, childbirth, etc. and the ones who consume a poor diet can also get this blood disease.
Know the symptoms: There are essentially nonspecific symptoms of anemia, but overall fatigue with very low energy levels as the body does not receive enough nutrition to perform various functions can be one of them. Reduced heart rate, fainting, and pallor of skin and whites of the eye are common indicators of this illness. Check with your doctor if you face any of these issues.
Foods for prevention: If you follow a healthy diet that is full of nutrients like iron, you can keep anemia at bay. Remember, weight is not an issue here. If you have a good diet intake, you need not worry about being slim. Often, women who are thin get labeled as anemic, which is far from truth. When it comes to nutrients, iron-rich foods should be eaten along with vitamin C to improve its absorption. Vitamin B12 also plays a significant role in absorption. Meat including red meat, lamb, pork, chicken, beet, ham, turkey, and seafood including salmon or tuna can be included in your diet. Other foods like legumes, soybeans, veggies (dark green leafy vegetables, spinach, peas, broccoli), dried fruits and nuts, tofu, pumpkin and eggs are rich sources of iron that can be consumed by vegetarians. Cereals like red rice, brown rice or fortified cereals with a good source of iron can also be included in the diet.
Don't miss out on iron, ladies! Women are likely to be anemic (with symptoms like fatigue and paleness) and hence they should constantly monitor for iron levels and shift to a diet rich in iron. Furthermore, iron supplements can be consumed in the form of tablets, syrup, or tablets with the guidance of a doctor. In severe cases, where there is a significant blood loss, especially with childbirth or internal bleeding, the sufferer may require transfusion. All in all, anemia is definitely manageable with planning of diet, especially during times the like menstruation and pregnancy. So, taking care on time is a vital step.

Anemia - What Diet Should You Follow?

Iron is an essential nutrient and mineral that is required by adults and children alike. Iron helps move oxygen from the lungs to the rest of the body and helps muscles store and use oxygen. It is especially important for children because it aids development and prevents anaemia. Untreated iron deficiency in children can cause physical and mental delays. It can lead to less healthy red blood cells in the child's blood stream which will cause a delay in the growth of physical and mental faculties.

Risk factors for iron deficiency in children

Infants and children at highest risk of iron deficiency include:

Babies who are born prematurely or have a low birth weight
Babies who drink cow's milk before age 1
Breast-fed babies who aren't given complementary foods containing iron after age 6 months
Babies who drink formula that isn't fortified with iron
Children ages 1 to 5 who drink more than 24 ounces (710 milliliters) of cow's milk, goat's milk or soy milk a day
Children who have certain health conditions, such as chronic infections or restricted diets
Children ages 1 to 5 who have been exposed to lead
Adolescent girls also are at higher risk of iron deficiency because their bodies lose iron during menstruation.
Symptoms of iron deficiency anaemia

The signs and symptoms of iron deficiency anaemia in children may include:

Pale skin
Fatigue or weakness
Slow cognitive and social development
Inflammation of the tongue
Difficulty maintaining body temperature
Increased likelihood of infections
Unusual cravings for non-nutritive substances, such as ice, dirt or pure starch
Prevent iron deficiency in children

Take steps to prevent iron deficiency in your child by paying attention to his or her diet. For example:

Breast-feed or use iron-fortified formula. Breast-feeding until your child is age 1 is recommended. If you don't breast-feed, use iron-fortified infant formula.
Encourage a balanced diet. When you begin serving your baby solids, typically between ages 4 months and 6 months, feed him or her foods with added iron, such as iron-fortified baby cereal. For older children, good sources of iron include red meat, chicken, fish, beans and dark green leafy vegetables. Between ages 1 and 5, don't allow your child to drink more than 24 ounces (710 milliliters) of milk a day.
Enhance absorption. Vitamin C helps promote the absorption of dietary iron. You can help your child absorb iron by offering foods rich in vitamin C, such as melon, strawberries, kiwi, broccoli, tomatoes and potatoes.
Consider iron supplements. If your baby was born prematurely or with a low birth weight or you're breast-feeding a baby older than 4 months and he or she isn't eating two or more servings a day of iron-rich foods, talk to your child's doctor about oral iron supplements.
Make sure that you watch out for the tell tale signs of iron deficiency and take the necessary precautions to avoid the same. If you wish to discuss about any specific child related problem, you can consult a specilized pediatrician and ask a free question.

Iron Deficiency In Children

Anemia (or anaemia) is a medical condition which generally occurs in a human body because of the lack of required healthy red blood cells (RBCs) or hemoglobin in the blood. Diagnosis of anemia is done through a blood test, a man is anemic when his hemoglobin level is less than 13.5 gram/100 ml and a woman is anemic when her hemoglobin level is less than 12.0 gram/100 ml.

Risk factors: People suffering from long-term or chronic diseases such as cancer are more susceptible of developing anemia. Hemoglobin is the salient constituent of red blood cells and is an iron rich protein. It provides the red color to the blood and binds oxygen. Red blood cells carry this oxygen to all the vital tissues and organs of the body. Due to lack of appropriate amount of red blood cells, the amount of blood required in a body to function normally is also low. One of the most prominent causes of occurrence of anemia is the deficiency of required amount of nutritional iron, vitamin B-12, and folate in the body. This iron is needed for the formation of hemoglobin. Apart from these causes, the other causes of anemia comprise of the following:

Loss of blood
Insufficient production of red blood cells (inadequate intake of iron, vitamin B-12)
Fast rate of destruction of red blood cells (disorders of liver and hemorrhage)
Diagnosis: It is relatively easy to detect an anemic person. The symptoms of anemia include pale appearance, complaint of cold, giddiness, unsteadiness, laziness, particularly when the person is in action or is standing up. Sometimes people suffering from anemia crave for eating clay, ice, or even dirt. Also, there are complains of exhaustion along with issues of constipation and concentration. Other indications of anemia are brittle nails, gasps for breath even in mild activities, and pain in the chest. Since the level of oxygen in the blood is low, there could be even scope of a heart attack.

A person suffering from anemia is usually diagnosed on the basis of a complete blood count. The blood test brings out if serum folate levels are quite low. In case the anemia is severe, sometimes doctors take the help of erythropoietin injections so as to foster the production of red blood cells in the bone marrow. In case there is bleeding or if the level of hemoglobin is low, it might become essential to carry out blood transfusion.

Treatment: Anemia is straightforward to diagnose and treat, but at the same time could prove to be deadly if it is left undiagnosed. Proper heed should be paid to the intake of adequate and required food which is rich in vitamins and minerals, dietary iron, folic acid, including other vitamins and minerals.

Anemia- How Does It Affect a Person's Health?

A healthy kidney produces a hormone known as the erythropoietin. The latter assists the bone marrow to produce an adequate amount of RBC that carries oxygen to every nook and corner of the body. A damaged kidney results in less RBC production, thereby, creating a condition known as anemia. The hemoglobin count in the blood reduces significantly in this condition.

Anemia is characterized by shortness of breath, weakness and tiredness. It can affect sleep and a loss of appetite. A patient suffering from anemia reports of frequent headaches and a faster heart rate. These symptoms also surface when a person suffers from chronic kidney diseases (CKD). The condition gets worse as the disease progresses.

Treating anemia:
A patient suffering from anemia should be treated on time as there are many pitfalls of a lower hemoglobin level. The treatment will give instant relief from other symptoms that might have arrived with CKD. Doctors frequently prescribe Erythropoiesis Stimulating Agent (ESA) for patients suffering from CKD and suffering from anemia due to the shortage of erythropoietin. ESAs can be injected through an injection or intravenously. These injections stimulate the bone marrow to produce more RBCs. However, studies have revealed that ESAs increase the chance of strokes, heart attacks and blood clots. Furthermore, they aggravate tumor growth and shorten life expectancy for cancer patients. People undergoing ESA treatment should have periodic check-ups to ensure that the hemoglobin count is normal and under control.

Iron
Iron count in the body has an important role in treating patients suffering from anemia and CKD. In case the level of iron is too low in the body, ESAs fail to improve the condition of an anemic patient. The ferritin count of a patient should be in the range of 100-800 mcg/L. One more test known as TSAT reveals the number of iron required to produce RBCs in the body. In case the iron count is less, doctors often suggest iron pills to bring the count to a more accepted level.

Other causes
There could be other reasons for anemia as well. A doctor might further investigate the level of B12 and folic acid present in the body. Even an inflammatory condition can lead to anemia. A decreased count of any of the above-mentioned ingredients can cause anemia to a patient suffering from EKD.

Food items necessary to improve the condition
A healthy diet helps in improving the condition of an anemic patient. Iron deficiency is best addressed by fish and beef. Food rich in vitamin C helps the body to absorb more iron in the body. Certain food items that block the entry of iron in the body include tea, milk, albumen (egg white) etc. Therefore, you should be strictly avoid these items from your diet.

Kidney Disease - How It Is Related With Anaemia?

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