Hereditary Angioedema is a rare skin related disorder and as the name suggests it is also a genetically inherited condition. This condition mainly afflicts the throat, abdomen and the limbs of the patient, with a certain kind of swelling. This swelling can become fatal if not treated on time. Here is everything you need to know about the condition and its treatment.

Causes: A rare genetic mutation of the SERPING1 gene can cause this condition. Usually, this gene is known to produce C1 esterase inhibitor, which is a kind of blood protein. This blood protein is an important element of one s immune system and is usually involved in the biochemical reactions that control the body s response to inflammation causing elements. This is done when the blood protein produces a hormone known as Bradykinin. If this blood protein does not function in a normal manner, then there is excessive production of this hormone, which leads to swelling and inflammation.

Type One: There are various types of Hereditary Angioedema that can affect various parts of the body. Type one is one of the most common kinds and can be found on the face, hands, abdomen, throat, as well as feet and genitals of the patient. The severity and frequency of attacks cannot really be predicted and the patient may suffer from attacks throughout his or her life. The best way to treat this type of Hereditary Angioedema is with the help of antihistamine drugs and prednisone which can fight allergic attacks.

Type Two: This kind of Hereditary Angioedema has the same symptoms as type one and is caused by a malfunction of the C1 inhibitor, rather than the Bradykinin hormone as one can see in type one. This condition can also be treated with anti-allergy drugs.

Type Three: This is very rare kind of Hereditary Angioedema. In fact, medical science is yet to find a conclusive body of knowledge that can point to the exact causes and symptoms of this condition. Coagulation is one of the main causes recognised so far. This condition is much more common in women than it is in men, and it usually shows up as facial swelling.

Timely Treatment: While there is no cure for this condition, one can prevent a flare up of the symptoms by taking C1 inhibitors and Bradykinin receptors as well as enzyme inhibitors. It is important to get early treatment for the symptoms and to have constant access to a hospital and its emergency unit. One should also keep track of attacks and symptoms and get regular check-ups done by a doctor to detect the earliest signs of the same to avoid fatalities.

What is Hereditary Angioedema and How Can it be Treated?

Bones are similar to a porous framework which is filled with minerals that make it hard and strong. With age, there is gradual degradation and the mineralized portion is lost, thereby leading to thinning of the bone. The word osteoporosis literally translates to porous bones, which is due to the gradual demineralisation. In addition to the natural ageing process, there are other diseases that can accelerate the demineralization process.

Women are more prone to demineralisation, and after the age of 40, they should take extra precaution to slow down the onset of the condition. The following are some ways to improve bone health and halt osteoporosis in the long run-

Diet: Ensure that your diet has sufficient amounts of vitamin D and calcium. Though calcium is the essential mineral for bone formation, vitamin D is required for the absorption of calcium, and therefore both these elements play a vital role in maintaining the quality of the bones in our body. Most people require about 1,000 mg of calcium and about 500 units of vitamin D for optimal bone health. This requirement goes up slightly in postmenopausal women.

Sun Exposure: In most people, exposure to the sun allows the body to make vitamin D, but careful sun protection prevents this from happening. Also, with age, the body s ability to form intrinsic vitamin D also declines. The body, therefore, relies on supplements. Most dairy products are good sources of calcium. In addition, spinach, salmon, turnips, and broccoli are some calcium-rich foods. Supplements of calcium carbonate or calcium citrate can be taken if your diet is lacking in calcium. Vitamin D also should be included in the supplementation. The treatment for osteoporosis is incomplete without these two supplements.

Exercise With Weights: The constructive tension that exercise puts on the body helps in bone building, whatever the age may be, which prevents the onset of osteoporosis. Any exercise which improves muscle mass strengthens the bones, and puts stress on the bones is advisable. Since the fractured area due to osteoporosis mainly includes the spine, lower back exercises, yoga, tai chi, and abdominal exercises all work wonders. Pick any of these and do them for 30 minutes three times a week.

Quit Smoking: Continuing to smoke while taking osteoporosis medications is completely useless. Nicotine negates all the effects which defeat the purpose of taking the medication and is as good as taking no medication at all. So if you want the bone thinning to stop, stop smoking.

Alcohol Consumption: While a drink or two per week is permissible, more than this can harm the bones significantly.

Constant Health Watch: Talk to your doctor about how other routine medications (if any) can affect your bone health. Also, identify how frequently you should check your bone mineral density and stick to the schedule.

Bone health and osteoporosis can be managed with some conscious efforts.

Bone Health And Osteoporosis - Know More About Them!

A small piece of bone is known as a fragment and it is very common that an avulsion fracture also tends to damage the protrusions of bone to which the tendons attach. This basically means that the tendon or ligament will come away from the bone and it will take a small piece of bone with it. It is sometimes very hard to find out what type of injury you have and this is why knowing the causes and symptoms of an avulsion fracture are very helpful in determining exactly how severe the injury is. 

Here are the causes of an avulsion fracture:

Explosive landing: Athletes who tend to jump or land with great impact tend to get these most commonly. Therefore, it is crucial for your health that if you participate in such sports, you do follow the correct method of jumping.
Explosive extension: Similar to how an athlete landing ferociously can get an avulsion fracture, someone who is extending the legs very violently and explosively during an exercise can also get an avulsion fracture. This is because the bone getting extended could very well damage the protrusions to which the tendons are attached. 
Symptoms
These are the two main causes of an avulsion fracture. There are not many symptoms of an avulsion fracture. This is because an avulsion fracture can only be determined by an MRI or by an X-ray scan. Therefore it is nearly impossible to diagnose that you have an avulsion fracture without looking at the results of the tests performed on the part of your body. However, the way you got the fracture and especially the details of it are very good indications of whether you have an avulsion fracture or not.

Avulsion Fracture - Common Causes Behind it

Knee is a hinge joint where the lower leg bone tibia meets the thigh bone femur. During osteoarthritis, cartilage or ligament defects and degenerative arthritis, knee replacement surgery is recommended world-wide to get relief from extreme pain. Knee replacement surgery, also known as knee arthroscopy, is a surgical procedure, in which the affected knee joint is replaced with synthetic material. The most likely candidates for total knee replacement are the patients with severe destruction of the knee joint coupled with progressive pain and impaired function.

Modern technological advances have made computer assisted knee replacement surgery extremely popular around the globe. In this surgery, the surgeon is assisted by a computer to remove the optimum amount and angle of the bone, which otherwise is done by inspecting manually. This is an excellent example of surgery through small incision and it eliminates the chances of human error. A perfect alignment and balance is achieved and hence longevity is also increased to 20 - 30 years. Knee replacement surgery is also specific to gender as the anatomy of male and female patients is different.

There are many types of knee replacements, most common being the total knee replacement or Total Knee Arthroplasty. In addition, there is partial knee replacement, bilateral knee replacement, revision knee replacement and knee arthroscopy.

In knee replacement surgery, the worn out surfaces of joints of knee are replaced with artificial implant of plastic and metal. The lower end of the femur bone is removed and replaced with a metal shell. The upper end of the lower leg bone (tibia) is also removed and replaced with a channelled plastic implant with a metal stem. A plastic ball is also added under the kneecap depending on its condition. These artificial components are commonly referred as prosthesis. The design of these highly flexible implants replicate knee, with the rotating knee replacement implants assist in backward and forward swing of the legs.

Patients whose knee joints have been damaged by either trauma or progressive arthritis should consider total knee replacement surgery. Post-surgical hospital stay after knee joint replacement is usually three to five days. The surgery has a very high success rate and shows dramatic improvement after a month. This improvement is most notable one month or more after surgery. The pain caused by the damaged joint is reduced significantly when the new gliding surface is constructed during surgery. Initially, patient will walk with the help of a walking aid until the knee is able to support full body weight. After six weeks, patient can walk comfortably with minimal assistance. Patients with artificial joints are prescribed to take antibiotics during the course of any elective invasive procedures including dental work. Physiotherapy is an essential part of rehabilitation and it will increase the muscle strength and patient can enjoy most activities, except running and jumping.

Knee Replacement

Your thyroid glands are important to the body because it produces essential hormones. However, if you suffer from hypothyroidism, your thyroid glands will not be able to produce these hormones sufficiently.

In the early stages of hypothyroidism, you will not detect any noticeable changes in your body or health. However, if you do not start treatment for the condition, you will soon start to experience symptoms, such as obesity and infertility. Joint pain is another serious symptom of hypothyroidism.

Symptoms of musculoskeletal pain related to hypothyroidism-

Hypothyroidism can lead to a range of muscular and skeletal disorders in your body. Here are some musculoskeletal symptoms you are likely to experience if you suffer from hypothyroidism.

Painful and stiff muscles, which mainly affect your hip and shoulder region

Swelling across the joints of feet and hands

Carpal tunnel syndrome, where pressure on a nerve in your wrist causes pain and tingling across the entire arm

Stiffness and pain in the joints

Treating hypothyroidism related muscle and joint pain-

Over-the-counter pain medications help deal with the pain and the swelling. However, they are a temporary solution for the discomfort. Treating hypothyroidism is the best way to reduce your pain and discomfort.

Your doctor will prescribe a levothyroxine supplement, which is a synthetic hormone. This medicine will rectify the imbalance in your hormone levels, which in turn will reduce pain in your muscles and joints. Apart from the joint pain, the medication will also lower your elevated cholesterol levels from hypothyroidism.

How to get the best results from the medication-

If you consume certain foods, supplements and medication while being on levothyroxine, the drug may not work effectively. Here is a look at some things to avoid when you are on the medication.

Excessive soy products

Excessive high-fibre diet

Foods with high iron content

Antacids that contain Aluminium hydroxide

Calcium supplements

For the best effects, you need to consume the hypothyroidism medication on an empty stomach. Your doctor will likely advise you to take the medicine first thing in the morning and then wait about an hour before having your meal. In some cases, you may need to take the drug before going to bed. However, ensure you consume the medicine at least 4 hours after the last meal for the day.

Hypothyroidism And Musculoskeletal Pain - Know More About Its Link!

A bone may break due to several reasons starting from a fall or an injury or a condition like osteoporosis that makes the bones brittle and leaves them susceptible to fractures. The fracture usually takes a few weeks to get fixed as the broken bones grow back together with the help of various forms of treatment including a plaster and sling applied by the orthopaedic specialist or general physician. Find out more about how bones heal with this article.

Types of fracture: Before we get to the subject of how bones heal, it is important to understand the various kinds of fractures recognised by doctors. The first kind is the complete fracture where the bone breaks into two distinct parts. The next kind is the greenstick fracture or hairline fracture where there is simply a crack on one side of the bone due to pressure. Further, there is the single fracture which occurs where there is breakage of the bone only in one place. A bowing fracture may occur when the bones bend instead of breaking completely. This kind of fracture is pretty common for children. The comminuted fracture happens when the bone is crushed or broken in many places. And finally, the open fracture is one where the bone ends up protruding from the skin.

Treatment: Once you have broken a bone, the doctor will conduct an X ray which will help in understanding the type of fracture and the extent of the damage caused. The doctor will then apply a cast and plaster that will help in bringing the bone back to its normal position so that it grows back with the main bone. In case the bone has broken into various parts or there is a complete fracture, then the doctor may even insert metal pins.

Natural healers: Bones are known as natural healers that can heal with the process of new cells and vessel production which rebuilds the bone by covering the broken ends and closing the gap caused due to the damage or the crack.
Clot: Once a bone has broken, a blood clot or a callus forms in the surrounding region, which kind of acts towards sealing the area.
Threads: Once these clots have formed, the new threads of the bone cells begin to grow slowly from the ends of the broken bones. This will grow on both sides of the affected and fractured bones, almost as if drawing a line from one broken end to another.
Absorption: Finally, the callus will be absorbed by the new cell and the gap will close.
See a doctor is you are experiencing any noticeable symptoms that may point towards bone fractures.

Broken Bones - How Do They Heal?

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