Neurological disorders are an enigmatic bunch. There are various ongoing researches to identify the exact cause and how to treat them. While some argue that schizophrenia is a chronic brain disorder, others do not agree with it and debate that the origin is yet to be identified and the factors which produce it are yet to be identified.

Factors supporting it to be a brain disease are listed below.

Scan images (MRI and PET scans) of people who have had schizophrenia are different and have a reduced volume of grey matter, especially in the frontal and temporal lobes. In some people, this loss could be as high as 25%. Serial images have shown that the loss begins in the outer (parietal) region and gradually spreads to the rest of the brain. There is a strong correlation between the extent of this grey matter loss and the severity of the symptoms more the loss, worse the symptoms. Severe symptoms include hearing voices, psychotic thoughts, delusions, hallucinations and severe depression. This grey matter reduction does not depend on whether the person has undergone treatment or not for the condition. 

The counter argument is that grey matter loss is not seen in patients with schizophrenia alone. A number of neurological disorders, including normal ageing, manifest as grey matter loss on the scan images. Also, another consoling news is that this grey matter loss is completely reversible.

The way neurotransmitters respond to stimuli in people with schizophrenia is also slightly different. There are two variations to this debate: that schizophrenia is caused by excessive amounts of dopamine or increased sensitivity to dopamine. There are two proofs for this hypothesis first, dopamine suppressants are useful as antipsychotic drugs and secondly drugs which produce the same effect as dopamine can cause hallucinations similar to those seen in schizophrenics. There could be other neurotransmitters involved too, but the dopamine connection is more strongly established.

The electrical activity of the brain as seen in EEG is very different and abnormal in schizophrenic people. This reduced brain activity is another indication of the fact that schizophrenia is another brain disorder. There is also a strong genetic component to schizophrenia. Family history correlation is also very strong. The correlation extends to the point that where there is a neurologic disorder in the first-degree relatives, the chances of developing schizophrenia is increased.

There are specific genes, mutations of which are also attributed to schizophrenia. While the risk factors are in place (as mentioned above), the environmental conditions (brain infections, head trauma, family/social stressors and toxins can all lead to the manifestation of the symptoms. With medications and support therapy, both prevention and symptom management are possible.

Schizophrenia - Is It Really a Brain Disease?

Schizophrenia has been recognized as a mental disorder that combines symptoms like hallucinations with distorted thinking and others like fright and severe paranoia. This condition is one that gets progressively worse over time and leads to delusional thinking. Oversleeping and complaining of fatigue are usually the earliest signs of this condition's onset. Eventually, it becomes a debilitating factor in the life of the patient, who will not be able to function in a normal way due to the severe symptoms.

Read on to know more about the types and causes of this condition:

Genetic Causes: Schizophrenia may be caused due to genetic factors and it may be a learned or inherited disorder. It is known to affect patients who have a parent or a sibling who may have suffered from this condition. Yet, one must also remember that Schizophrenia can only be influenced by genetics, and not determined by the same.
Environmental Causes: When there has been an exposure to a viral infection during the pre natal stage, the patient is susceptible to this condition. Also, it may affect children who have been subject to the loss of a parent or separation at an early age. Physical and emotional abuse in one's childhood may also bring on this condition. Low level of oxygen at the time of birth is one of the causes of this condition in many patients.
Anomalies in Brain Structure: When the brain ventricles of the patient are enlarged, he or she may be prone to this condition. Also, anomalies in the temporal lobes and amygdala have links with the onset of this condition.
Types: A wide variety of mental and medical conditions can manifest with psychotic symptoms that must be considered in the differential diagnosis of schizophreniform disorder. These include psychotic disorder due to another medical condition or its treatment; delirium or major neurocognitive disorder; substance/medication-induced psychotic disorder or delirium; depressive or bipolar disorder with psychotic features; schizoaffective disorder; other specified or unspecified bipolar and related disorder; depressive or bipolar disorder with catatonic features; schizophrenia; brief psychotic disorder; delusional disorder; other specified or unspecified schizophrenia spectrum and other psychotic disorder; schizotypal, schizoid, or paranoid personality disorders; autism spectrum disorder; disorders presenting in childhood with disorganized speech; attention-deficit/hyperactivity disorder; obsessive-compulsive disorder; posttraumatic stress disorder; and traumatic brain injury.
Since the diagnostic criteria for schizophreniform disorder and schizophrenia differ primarily in duration of illness, the discussion of the differential diagnosis of schizophrenia also applies to schizophreniform disorder. 

Brief psychotic disorder. Schizophreniform disorder differs in duration from brief psychotic disorder, which has a duration of less than 1 month.

Residual Schizophrenia is a condition where the patient does not experience the various debilitating symptoms of the condition, and is on the road to recovery. Yet, even in this type of Schizophrenia, the patient will not really show any interest in life and the activities around him or her. Finally, the last type of Schizophrenia is Schizoaffective Disorder which is characterised by the symptoms of Schizophrenia as well as the symptoms of major mood disorders. When combined, this condition can lead to major complications and complex behavior.

A patient suffering from this condition will need to see a mental health specialist like a psychiatrist or a psychologist on an immediate basis. The treatment will be carried out on a long term basis for the results to start appearing.

Schizophrenia - Know the Causes Behind it

Schizophrenia affects over 1% of the world s population and affects the way a person thinks, feels and behaves. In most cases, it is diagnosed when a person is between the ages of 16 to 25. This condition can be hereditary and is said to affect men more often than women. Schizophrenia is characterized by an inability to distinguish between real and imaginary which can lead to delusions, social withdrawal, hallucinations and other forms of social and occupational dysfunction.

Schizophrenia affects different people in different ways. On the basis of the type of symptoms exhibited, this disease has been categorized into 5 sub types. These are:

Paranoid schizophrenia: This type of schizophrenia is characterized by delusions and hallucinations that may make the person exhibit paranoid behaviour. These people often feel like they are being watched or followed and may have delusions of grandeur. They may also get angry quickly on minor issues and show signs of anxiety and hostility.
Disorganized schizophrenia: In such cases, the person may behave in ways that are difficult to understand or speak in broken sentences and have difficulty structuring a sentence. They may also display inappropriate behaviour and react in ways not suitable to the occasion. People suffering from disorganized schizophrenia may also neglect their personal hygiene.
Catatonic schizophrenia: People suffering from catatonic schizophrenia may swing between immobility and periods of rapid movement. They may stay quiet for hours or talk rapidly repeating everything they hear. These people have a high risk of harming themselves as they are usually unable to look after themselves and complete daily activities.
Undifferentiated schizophrenia: People suffering from this type of schizophrenia exhibit behaviour that fits into more than one type of schizophrenia. From time to time they may have hallucinations, suffer from delusions or display catatonic behaviour and disorganized behaviour or speech.
Residual schizophrenia: Even though a person may not be currently showcasing any signs of schizophrenia, they are said to have residual schizophrenia. Such people need to have had at least one schizophrenic episode. These people may exhibit symptoms later or be in complete remission.
With schizophrenia, an early diagnosis can make treatment easier and hence if you notice anyone exhibiting signs of schizophrenia, you must advise them to seek medical help immediately. Schizophrenia cannot be cured but it can be managed with a combination of typical or atypical medication and cognitive therapy. The latter can be in the form of self-help groups, housing and employment programs, counselling and therapy. 

Types Of Schizophrenia - How Can They Be Dealt With?

Schizophrenia is a very serious psychological disorder which influences how a person feels, thinks, acts and reacts. A patient suffering from schizophrenia may experience issues recognising what is real and what is nonexistent; might be lethargic or unresponsive, and may experience issues communicating ordinary feelings in social situations.

The reason for schizophrenia is still hazy. A few theories and speculations about the reason for this disorder include genes (hereditary qualities), biology of the body (the unevenness in the brain s functioning); or persistent viral infections and immune disorders. Some of the problems faced by schizophrenics are as follows:

Delusions: People may feel that somebody is keeping an eye on him or her, or that they are somebody well known and famous.
Development and movement problems: These include behaving in a strange manner, pacing around, posturing or shaking forward and backwards for no reason.
Thought issue: Jumping from one topic to another in an unreasonable manner is also one of the symptoms or challenges of this condition. People may make up their own particular words or sounds.
Hallucinating: Seeing, smelling, tasting, hearing or feeling something that does not generally exist. The most widely recognised symptom is listening to nonexistent voices that give orders or commands to the patients.
Absence of feelings and emotions: An irregular feeling or expression may be experienced. For instance, crying at a joke when a typical reaction would be to laugh at it.
Despite these, some of the other very common problems faced by schizophrenic patients are as follows:

Social withdrawal from family and friends
Problems affecting in the ordinary exercises of life, for example, at work or school
Poor hygiene and lack of cleanliness
Mental shock
Loss of proper sentence formation
Issues deciding
Overlooking or losing things
Issues understanding ordinary sights, sounds, and sentiments.
Moving rapidly starting with one thought then onto the next.
Pacing and strolling in circles
Unreasonable written work, yet without any meaning.
A person with schizophrenia is twice as likely to end up diabetic or experience the ill effects of the chronic obstructive pneumonia disease (COPD) than the general population. Individuals with schizophrenia regularly commit the normal error of attempting to overlook the sickness thinking that it does not exist.

Schizophrenia has crushed a considerable amount of lives throughout the years. The indications of schizophrenia can be exceptionally scary and unnerving. There are different treatment techniques that one can access to improve the lives of the people who experience the ill effects of schizophrenia. Treatment of schizophrenia has, however essentially enhanced throughout the years, and there is no motivation to trust that it will not keep on doing so. In case that you or someone close to you has schizophrenia, look for treatment in light of the fact that your odds of recovery are good and your odds of change are great.

Schizophrenia - Common Problems Faced By A Person Suffering From It!

Schizophrenia is a brain disorder that affects how a person sees the world. Schizophrenia makes it difficult for you to distinguish between what is real or unreal. It can stop you from thinking clearly, handling your emotions properly or functioning in a normal way. However, one can manage schizophrenia effectively. The best way is to recognise the signs and symptoms that one might be having. Here is how you can recognise the symptoms of schizophrenia:

Delusions: A delusion is an idea that a person might have despite there being obvious evidence that it is not true or does not exist. These are extremely common in schizophrenia and occur in ninety percent of the people with this disorder. These delusions can be of many types:
Delusion of persecution: When a person believes that someone is out to get them.
Delusion of reference: a very neutral environmental event tends to have a personal meaning to them. They might think that a person on the TV or a billboard is trying to send a message specifically for them.
Delusion of control: In this, a person believes that his or her actions are being controlled from the outside.
Hallucinations: These are sensations or sounds that a person experiences as real when they only exist in that person s mind. Visual hallucinations are relatively more common. These are only meaningful to the person who is experiencing them. These voices or visuals are usually horrific, vulgar, abusive or critical. They tend to increase in intensity when the person is alone.
Disorganized speech: People who suffer from this order have a hard time maintaining or concentrating on certain thoughts. They may start sentences and forget what they were talking about. They might even go off track in the middle of conversations. People with this disorder usually say illogical things and speak incoherently. A patient may also make up words or phrases that only have a meaning to them.
Disorganized symptoms: A person is unable to take care of himself or herself or their work. They face a decline in their overall daily functioning and their behaviours are bizarre and may have no purpose. People with this disorder cannot control their impulses.
Negative symptoms: This refers to the absence of behaviours that usually appear normal to other people. These include lack of expressing oneself emotionally, lack of interest or enthusiasm. These also include speech difficulties or abnormalities as well as their lack of interest in the world.
Schizophrenia can be caused due to many reasons. These include lack of oxygen during birth, exposure to a virus during infancy, physical or sexual abuse, depression, hereditary components or enlarged brain ventricles. This disorder can affect a patient s mental as well as physical health and can endanger the people around them as well as their relationships. Hence, the signs and symptoms should be recognised as early as possible in order to get the right kind of treatment.

Schizophrenia - How To Recognize The Signs?

Schizophrenia is a psychiatric disorder in which a person s mood, knowledge, thought and several other characteristics gets disturbed. We can notice most of the adults and old people with few symptoms of schizophrenia, which are most commonly left unidentified. The exact cause of schizophrenia is not yet known. The person feels that they are being constantly watched, they feel the presence of someone or something, which is not actually there. They are always suspicious and think that other people are gossiping and thinking about them.

Possible causes of Schizophrenia
Though the exact cause of schizophrenia is not known there are few factors, which contribute to the cause of schizophrenia.

    Genetic factors: People with a family history of schizophrenia are at higher risk of getting schizophrenia.
    Environmental factors: Environmental factors include excessive stress during pregnancy or later stages of life. Several other factors during pregnancy and childhood are responsible for causing schizophrenia. These factors are:
        Decreased oxygen level during delivery due to premature birth or prolonged labour
        Parental loss or separation in early stages of life
        Parental exposure to virus or during infancy
        Childhood physical or sexual abuse
        Abnormal brain structures and brain chemistry

Sings and symptoms of schizophrenia

    Hallucination: To see, feel or hear anything that really does not exist is known as hallucination.
    Delusion: A thought or belief of a person, which is either false or impossible in reality is known as delusion.
    Thought and speech disturbances: The thought process and speech of a schizophrenic will be disorganized, due to which he or she  will fumble or is distracted as they are unable to align their thoughts.
    Difficulty in concentrating: It is difficult for people suffering from schizophrenia to concentrate on the task at hand.
    Erratic behaviour: People suffering from schizophrenia tend to behave erratically, either they will be too jumpy or will be perfectly still for hours at a stretch. Most people belief that those who are suffering from schizophrenia are often violent in nature, which actually is not the case.

Treatment for schizophrenia
Schizophrenia can be treated, if identified at an early stage. . It is best advised to consult a psychiatrist the moment you spot the symptoms. Anti psychotic drugs, self help behaviour change, counselling and rehabilitation are few treatment modalities available for schizophrenia.

Schizophrenia: Can Genetics be the Reason Behind it?

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