Neurological disorders are an enigmatic bunch. There are various ongoing researches to identify the exact cause and how to treat them. While some argue that schizophrenia is a chronic brain disorder, others do not agree with it and debate that the origin is yet to be identified and the factors which produce it are yet to be identified.

Factors supporting it to be a brain disease are listed below.

Scan images (MRI and PET scans) of people who have had schizophrenia are different and have a reduced volume of grey matter, especially in the frontal and temporal lobes. In some people, this loss could be as high as 25%. Serial images have shown that the loss begins in the outer (parietal) region and gradually spreads to the rest of the brain. There is a strong correlation between the extent of this grey matter loss and the severity of the symptoms more the loss, worse the symptoms. Severe symptoms include hearing voices, psychotic thoughts, delusions, hallucinations and severe depression. This grey matter reduction does not depend on whether the person has undergone treatment or not for the condition. 

The counter argument is that grey matter loss is not seen in patients with schizophrenia alone. A number of neurological disorders, including normal ageing, manifest as grey matter loss on the scan images. Also, another consoling news is that this grey matter loss is completely reversible.

The way neurotransmitters respond to stimuli in people with schizophrenia is also slightly different. There are two variations to this debate: that schizophrenia is caused by excessive amounts of dopamine or increased sensitivity to dopamine. There are two proofs for this hypothesis first, dopamine suppressants are useful as antipsychotic drugs and secondly drugs which produce the same effect as dopamine can cause hallucinations similar to those seen in schizophrenics. There could be other neurotransmitters involved too, but the dopamine connection is more strongly established.

The electrical activity of the brain as seen in EEG is very different and abnormal in schizophrenic people. This reduced brain activity is another indication of the fact that schizophrenia is another brain disorder. There is also a strong genetic component to schizophrenia. Family history correlation is also very strong. The correlation extends to the point that where there is a neurologic disorder in the first-degree relatives, the chances of developing schizophrenia is increased.

There are specific genes, mutations of which are also attributed to schizophrenia. While the risk factors are in place (as mentioned above), the environmental conditions (brain infections, head trauma, family/social stressors and toxins can all lead to the manifestation of the symptoms. With medications and support therapy, both prevention and symptom management are possible.

Schizophrenia - Is It Really a Brain Disease?

Schizophrenia is a disease of the mind that is usually degenerative in nature. The complex disorder is generally characterized by symptoms, such as delusions, hallucinations (both auditory and visual) and disturbances in speech and is usually chronic in nature. The symptoms are not regular and can appear at any point of time. So it is highly possible that a person suffering from schizophrenia may sometimes bear resemblance to any other normal person and all of a sudden, might exhibit symptoms typical of Schizophrenia.

The causes of Schizophrenia include:

Brain Dysfunction: Abnormalities in the cerebral cortex (the cerebrum s outer covering that is vital in regulating consciousness) of the brain is the most common cause of this disorder. This is due to the presence of abnormally enlarged ventricles in that region. The decreased brain size owing to the enlarged ventricles is often related to the hallucinations and delusions experienced by schizophrenics.
Genetic Factors: Studies have also stated  genetics  to be an important cause behind this disorder. Closer the family ties, higher the risks of transmitting the disorder.
Biochemical Factors: More than one neurotransmitter is being targeted by recent drugs to control schizophrenia.

Symptoms which most people do not experience normally, but are found in people diagnosed with schizophrenia are said to be positive symptoms. They are:

Hallucinations: These are sensory experiences of things that do not exist outside the mind. Hallucinations usually manifest in the form of auditory or visual images.
Delusions: Delusions on the other hand are false beliefs one has about oneself. Delusions are of 3 major types:
Grandeur: Wherein the person imagines himself to be a famous personality
Persecution: The belief that somebody somewhere is plotting against you and the whole world is going to get you.
Control: The belief that a larger force, let s say a witch, a demon or even a duck for that matter is controlling your actions.
These positive symptoms generally respond well to medications.
In addition to this, schizophrenics think and speak differently than the rest of the society. They jump from idea to idea, lose track of speech mid-way and often speak in fragmented and haphazardly joined sentences. They are, in fact, unable to fix their attention on anything in particular.
Examples of the most common negative symptoms include:

The flat effect: The individual basically shows no facial expression and always has a flat emotionless mask on while staring into space. At times, they have inappropriate reactions to situations. Example - they might laugh at somebody's death and cry ad get angry when something good happens. 
Avolition: This condition occurs when the individual just sit for hours doing nothing as well as behaves in a way lacking any motivation or enthusiasm.

Schizophrenia -  Can Biochemical Factors be the Cause Behind it?

When you hear the word  schizophrenia , the first thing that comes to mind are those serial killers shown on the TV or you call it split personality. But that is not the true meaning of it. It is not split personality or some kind of violent illness. Schizophrenia is a severe chronic mental illness which makes it difficult to differentiate between what is real and what is false.

As this is a mental illness, you will not be able to see any changes physically. You need to understand the symptoms of schizophrenia in order to know if a person is suffering from this problem. There are different kinds of symptoms that are used for diagnosing schizophrenia, but they all differ from person to person. Also, the symptoms that you see now, may not be seen later as the disease progresses. There are different types of schizophrenia and each has different symptoms.

Here is a list of the different types of schizophrenia and the most predominant and significant symptoms of each type.

Paranoid Schizophrenia: People suffering from paranoid schizophrenia are characterized by strong auditory hallucinations and of being persecuted. However, they are very normal and function normally. But they are not ready to discuss their feelings openly and the symptoms are not observable. Other symptoms include anger, hostility and disorganized speech.
Disorganized Schizophrenia: As the name suggests, people with disorganized schizophrenia exhibit disorganized thoughts. Delusions and hallucination may not be seen in this type of schizophrenia. The behavior of the affected person is quite disorganized or it is difficult to understand what they are saying. In fact, some emotions exhibited by the affected person are hard to understand or they are not at all relevant to the current situation. Their daily routine and activities will also be affected.
Catatonic Schizophrenia: People with catatonic schizophrenia are characterized by increased or decreased movement. This symptom actually varies from person to person. Some people stay at a place for a long time without any kind of movement and some people keep moving for hours and do not stop. They do not speak for hours and sometimes they keep repeating the same thing over and over again. This has to be treated immediately as they will not be able to manage even their daily routine with this kind of behavior.
Undifferentiated Schizophrenia: Undifferentiated schizophrenia is a condition where the symptoms do not fall into any of the above three types. You will also be able to observe hallucinations, delusions, anger, disorganized speech or catatonic behavior.
Residual Schizophrenia: As the name suggests, it is the residue of schizophrenia behavior, but it is less severe as compared to the past. Delusions, hallucination and disorganized speech may still be present but compared to the past, the patient would be doing better. 

Schizophrenia - 5 Types & Their Signs!

Schizophrenia is a psychiatric disorder in which a person s mood, knowledge, thought and several other characteristics gets disturbed. We can notice most of the adults and old people with few symptoms of schizophrenia, which are most commonly left unidentified. The exact cause of schizophrenia is not yet known. The person feels that they are being constantly watched, they feel the presence of someone or something, which is not actually there. They are always suspicious and think that other people are gossiping and thinking about them.

Possible causes of Schizophrenia
Though the exact cause of schizophrenia is not known there are few factors, which contribute to the cause of schizophrenia.

    Genetic factors: People with a family history of schizophrenia are at higher risk of getting schizophrenia.
    Environmental factors: Environmental factors include excessive stress during pregnancy or later stages of life. Several other factors during pregnancy and childhood are responsible for causing schizophrenia. These factors are:
        Decreased oxygen level during delivery due to premature birth or prolonged labour
        Parental loss or separation in early stages of life
        Parental exposure to virus or during infancy
        Childhood physical or sexual abuse
        Abnormal brain structures and brain chemistry

Sings and symptoms of schizophrenia

    Hallucination: To see, feel or hear anything that really does not exist is known as hallucination.
    Delusion: A thought or belief of a person, which is either false or impossible in reality is known as delusion.
    Thought and speech disturbances: The thought process and speech of a schizophrenic will be disorganized, due to which he or she  will fumble or is distracted as they are unable to align their thoughts.
    Difficulty in concentrating: It is difficult for people suffering from schizophrenia to concentrate on the task at hand.
    Erratic behaviour: People suffering from schizophrenia tend to behave erratically, either they will be too jumpy or will be perfectly still for hours at a stretch. Most people belief that those who are suffering from schizophrenia are often violent in nature, which actually is not the case.

Treatment for schizophrenia
Schizophrenia can be treated, if identified at an early stage. . It is best advised to consult a psychiatrist the moment you spot the symptoms. Anti psychotic drugs, self help behaviour change, counselling and rehabilitation are few treatment modalities available for schizophrenia.

Schizophrenia: Can Genetics be the Reason Behind it?

What is schizophrenia?
We all know it as a debilitating mental illness that plagues people across the globe. Schizophrenic patients often feel like they are being overtaken by situations and events that are beyond their control. They may complain of seeing people who are not there or hearing voices where there are none. This happens because the neurotransmitters in the brain of the patient do not function appropriately. There are various types, causes and symptoms of this disease. Read up to know more.

Symptoms: psychotic symptoms like delusion are common in patients suffering from this disease. Also, the patient may be severely blunted in the emotional sense, and may bear a lost look and wear a feeling of loss or absence at all times. The thought process or cognition of the patient may also suffer in such cases. Poor concentration and lack of coordination are some symptoms of this kind of suffering. Hallucinations and distorted thought processes also characterise the patient to a great extent. The patient may also display certain typical symptoms like social withdrawal, extreme apathy, and lack of motivation. The patient will also be in an emotionally numb state once the delusions have lessened.

Causes: so what causes schizophrenia, really? while no tests or conclusive examinations exist to pin point the exact diagnosis or cause of the disease, there are many factors that can contribute to the development and progression of the same. Hereditary factors play up in many cases while chemical imbalances in the brain also lead to this condition. The serotonin levels and the functioning of the neurotransmitters are the most significant causes of this disease, in such cases. Excessive abuse of drugs like lsd and cannabis can also contribute to this condition, while family relations and a dysfunctional environment can also lead to this disease.

Types: there are many different kinds of schizophrenia. One of them is paranoid schizophrenia, which makes the patient highly suspicious. Disorganised schizophrenia can lead to incoherence in speech and thought. Catatonic schizophrenia can cause social withdrawal while residual schizophrenia can lead to a complete lack of motivation. Finally, schizoaffective disorder can lead to major mood swings.

The various kinds of schizophrenia are characterised by varying degrees of mood swings, depression, paranoia and delusional thinking. The progression of the disease can be checked with the help of cognitive behavioural therapy, which can help in reprogramming the brain of the patient to a great degree. Rehabilitation programs as well as case management can help in the long run. But the key here is to recognise the symptoms early on and get the treatment or counselling started to reduce the symptoms and their spread.

Schizophrenia: Types, Causes and Symptoms

Bipolar disorder:

Also known as manic-depressive disorder, bipolar disorder is the sudden change in mood, which might take a swing from depression to mania. It is a very severe disorder and can bring about unstable and precarious behavior. The risk of having suicidal tendencies is also quite high. Bipolar disorder is usually treated with medicines alongside therapy.

Symptoms:

1. Bipolar mania
2. Hypomania
3. Depression
4. Mood swings

The mood swings do not follow any particular pattern.

Schizophrenia Disorder

Schizophrenia is a chronic mental disorder which affects the general behavior and lifestyle of a person. Schizophrenics might face a difficulty in distinguishing between the real and the imaginary.
Contrary to public belief, schizophrenia is neither split personality nor multiple personalities. It is not an after effect of any previous traumatic experience. It might be genetic or a result of chemical imbalance in the brain chemicals.

Symptoms:

1. Paranoia
2. Senseless talking
3. Feeling apathetic
4. Insomnia
5. Personality change
6. Hallucinations
7. Delusions
8. Withdrawal from society
9. Attention deficit disorder or add

No specific medicine is available for schizophrenia. Usually, rehabilitation is advised to regain confidence and recover skills required for a productive life.

Psychosis

Similar to schizophrenia, psychosis is another mental disorder which is characterized by hallucinations and delusions. Psychosis is extremely dangerous and harmful as it might spur you to cause self-inflicted wounds and pain. It is of utmost importance to consult a doctor immediately after experiencing psychotic symptoms.

Symptoms:

1. Hallucinations
2. Delusions
3. Depression
4. Anxiety
5. Suspicion
6. Insomnia or hypersomnia
7. Withdrawal from society
8. Attention deficit disorder or add
9. Attention deficit hyperactivity disorder or ADHD

The only available diagnosis for psychosis is a psychiatric evaluation. Certain medical tests and x-rays may also be executed along with it to detect the underlying cause. Psychosis may be caused due to Parkinson's disease, Huntington's disease, brain tumors, Alzheimer's disease, epilepsy, etc.

Although there aren't any medical complications in psychosis, it should not be left untreated due to its harmful effects. Medication and therapy are the known cures of psychosis.

Symptoms of Bipolar Disorder, Schizophrenia Disorder and Psychosis

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