Schizophrenia is a disease of the mind that is usually degenerative in nature. The complex disorder is generally characterized by symptoms, such as delusions, hallucinations (both auditory and visual) and disturbances in speech and is usually chronic in nature. The symptoms are not regular and can appear at any point of time. So it is highly possible that a person suffering from schizophrenia may sometimes bear resemblance to any other normal person and all of a sudden, might exhibit symptoms typical of Schizophrenia.

The causes of Schizophrenia include:

Brain Dysfunction: Abnormalities in the cerebral cortex (the cerebrum s outer covering that is vital in regulating consciousness) of the brain is the most common cause of this disorder. This is due to the presence of abnormally enlarged ventricles in that region. The decreased brain size owing to the enlarged ventricles is often related to the hallucinations and delusions experienced by schizophrenics.
Genetic Factors: Studies have also stated  genetics  to be an important cause behind this disorder. Closer the family ties, higher the risks of transmitting the disorder.
Biochemical Factors: More than one neurotransmitter is being targeted by recent drugs to control schizophrenia.

Symptoms which most people do not experience normally, but are found in people diagnosed with schizophrenia are said to be positive symptoms. They are:

Hallucinations: These are sensory experiences of things that do not exist outside the mind. Hallucinations usually manifest in the form of auditory or visual images.
Delusions: Delusions on the other hand are false beliefs one has about oneself. Delusions are of 3 major types:
Grandeur: Wherein the person imagines himself to be a famous personality
Persecution: The belief that somebody somewhere is plotting against you and the whole world is going to get you.
Control: The belief that a larger force, let s say a witch, a demon or even a duck for that matter is controlling your actions.
These positive symptoms generally respond well to medications.
In addition to this, schizophrenics think and speak differently than the rest of the society. They jump from idea to idea, lose track of speech mid-way and often speak in fragmented and haphazardly joined sentences. They are, in fact, unable to fix their attention on anything in particular.
Examples of the most common negative symptoms include:

The flat effect: The individual basically shows no facial expression and always has a flat emotionless mask on while staring into space. At times, they have inappropriate reactions to situations. Example - they might laugh at somebody's death and cry ad get angry when something good happens. 
Avolition: This condition occurs when the individual just sit for hours doing nothing as well as behaves in a way lacking any motivation or enthusiasm.

Schizophrenia -  Can Biochemical Factors be the Cause Behind it?

Schizophrenia is a debilitating mental and emotional condition that is characterised by a heavily distorted thought process as well as hallucinations and even extreme fear that borders on paranoia. Let us find out more about this debilitating disease:

Causes:
1. Genetics: genetic factors play an important role in the development of schizophrenia.
2. Environment: possible environmental factors include obstetric complications, the mother's exposure to influenza during pregnancy or starvation. It has also been suggested that stress, trauma even migration can lead to the emergence of schizophrenia. 
3. Neurodevelopmental factors: schizophrenia appears to be a neurodevelopmental disorder. That is changes that cause the illness have been occurring from the earliest stages of development even in utero, and may continue to influence the development of the brain over the first 25 years of life. 

Symptoms: 
This disease has a variety of symptoms include cognitive and emotional ones that can vary in the degree and severity. One of the most common symptoms included hallucinations and delusions where the patient may end up imagining things that do not really exist. The patient may also be gripped by sudden and crippling fear like paranoia, which can be debilitating as far as everyday functioning of the person goes. The symptoms can also interfere with the way a person deals with situations and life skills on a cognitive basis. Withdrawal and hopelessness are also a part of this disease.

Treatment: 
The earliest signs and symptoms must be referred to a psychiatrist. The treatment involves the management of the case of an individual basis along with psychological rehabilitation programs and inclusion of the patient in self-help groups. Housing and employment programs must also be availed so as to keep the patient busy. Also, behaviour therapy will be required in such cases. The mode of counselling should usually be on a one on one basis, although many doctors also suggest that group therapy can help in showing examples of progress so as to encourage the patient to change and get a new lease of life.

Schizophrenia: Causes, Symptoms and Treatment

Neurological disorders are an enigmatic bunch. There are various ongoing researches to identify the exact cause and how to treat them. While some argue that schizophrenia is a chronic brain disorder, others do not agree with it and debate that the origin is yet to be identified and the factors which produce it are yet to be identified.

Factors supporting it to be a brain disease are listed below.

Scan images (MRI and PET scans) of people who have had schizophrenia are different and have a reduced volume of grey matter, especially in the frontal and temporal lobes. In some people, this loss could be as high as 25%. Serial images have shown that the loss begins in the outer (parietal) region and gradually spreads to the rest of the brain. There is a strong correlation between the extent of this grey matter loss and the severity of the symptoms more the loss, worse the symptoms. Severe symptoms include hearing voices, psychotic thoughts, delusions, hallucinations and severe depression. This grey matter reduction does not depend on whether the person has undergone treatment or not for the condition. 

The counter argument is that grey matter loss is not seen in patients with schizophrenia alone. A number of neurological disorders, including normal ageing, manifest as grey matter loss on the scan images. Also, another consoling news is that this grey matter loss is completely reversible.

The way neurotransmitters respond to stimuli in people with schizophrenia is also slightly different. There are two variations to this debate: that schizophrenia is caused by excessive amounts of dopamine or increased sensitivity to dopamine. There are two proofs for this hypothesis first, dopamine suppressants are useful as antipsychotic drugs and secondly drugs which produce the same effect as dopamine can cause hallucinations similar to those seen in schizophrenics. There could be other neurotransmitters involved too, but the dopamine connection is more strongly established.

The electrical activity of the brain as seen in EEG is very different and abnormal in schizophrenic people. This reduced brain activity is another indication of the fact that schizophrenia is another brain disorder. There is also a strong genetic component to schizophrenia. Family history correlation is also very strong. The correlation extends to the point that where there is a neurologic disorder in the first-degree relatives, the chances of developing schizophrenia is increased.

There are specific genes, mutations of which are also attributed to schizophrenia. While the risk factors are in place (as mentioned above), the environmental conditions (brain infections, head trauma, family/social stressors and toxins can all lead to the manifestation of the symptoms. With medications and support therapy, both prevention and symptom management are possible.

Schizophrenia - Is It Really a Brain Disease?

Are you aware of the schizophrenia and the adverse effects it inflicts on a person? Schizophrenia is a chronic and extremely severe mental disorder that affects how a person thinks, behaves, and feels. Schizophrenia patients seem like they are not aware of reality. The condition requires lifelong treatment, even after the symptoms leave. There are various types of treatments, which are used for schizophrenic patients. The treatment is usually guided by an experienced psychiatrist. 

The various modes of treatments are as follows:
Medications: Medications are very important for the treatment of schizophrenia, and antipsychotic drugs are most commonly used. They help in managing the symptoms by affecting dopamine. Treatment using antipsychotic drugs aims at managing the symptoms effectively. Antidepressants and anti-anxiety drugs are also used for treatment. Several weeks are required for these medicines to show results. Most of the medications used for schizophrenia treatment are associated with severe side effects and are thus avoided by many people. The patient s cooperation with treatment determines the choice of drug.

First generation antipsychotics: These medicines are associated with adverse neurological side effects, such as the possibility of developing tardive dyskinesia, which is an irreversible movement disorder.
Second generation antipsychotics: These medicines are preferred because of the lower risk of adverse side effects on the body than first generation medicines.
Psychological interventions: When the patient s psychosis decreases, psychological and psychosocial interventions are required. They include the following:

Individual therapy: Psychotherapy is important for normalizing a patient s regular thought patterns. Learning about ways to deal with stress, and identifying warning signs can help patients manage their condition better.
Social skills training: This aims at improving a schizophrenic person s social interactions, communication and his/her ability to take part in daily activities.
Family therapy: Family therapy is important for educating the families of schizophrenic patients about the disorder, and let them know about the ways to deal with it.
Vocational rehabilitation and supported employments: Most people with schizophrenia need some kind of daily living support. Programs are offered by several communities and self-help groups for helping schizophrenic people with housing, jobs, crisis situations. With proper treatment, most schizophrenic people manage to deal with their symptoms and illness.

Hospitalization: During emergency or crisis periods of extreme symptoms, a patient may need to be hospitalized to get proper nutrition, basic hygiene, sufficient sleep, and safety.
Electroconvulsive therapy or ECT is carried out for schizophrenic patients who do not respond to drug treatment. This therapy is also beneficial for patients who have got depression. It is recommended for you to consult a doctor on experiencing any symptom of schizophrenia.


Schizophrenia - Different Modes Of Treatment That Are Followed!

Schizophrenia has been recognized as a mental disorder that combines symptoms like hallucinations with distorted thinking and others like fright and severe paranoia. This condition is one that gets progressively worse over time and leads to delusional thinking. Oversleeping and complaining of fatigue are usually the earliest signs of this condition's onset. Eventually, it becomes a debilitating factor in the life of the patient, who will not be able to function in a normal way due to the severe symptoms.

Read on to know more about the types and causes of this condition:

Genetic Causes: Schizophrenia may be caused due to genetic factors and it may be a learned or inherited disorder. It is known to affect patients who have a parent or a sibling who may have suffered from this condition. Yet, one must also remember that Schizophrenia can only be influenced by genetics, and not determined by the same.
Environmental Causes: When there has been an exposure to a viral infection during the pre natal stage, the patient is susceptible to this condition. Also, it may affect children who have been subject to the loss of a parent or separation at an early age. Physical and emotional abuse in one's childhood may also bring on this condition. Low level of oxygen at the time of birth is one of the causes of this condition in many patients.
Anomalies in Brain Structure: When the brain ventricles of the patient are enlarged, he or she may be prone to this condition. Also, anomalies in the temporal lobes and amygdala have links with the onset of this condition.
Types: A wide variety of mental and medical conditions can manifest with psychotic symptoms that must be considered in the differential diagnosis of schizophreniform disorder. These include psychotic disorder due to another medical condition or its treatment; delirium or major neurocognitive disorder; substance/medication-induced psychotic disorder or delirium; depressive or bipolar disorder with psychotic features; schizoaffective disorder; other specified or unspecified bipolar and related disorder; depressive or bipolar disorder with catatonic features; schizophrenia; brief psychotic disorder; delusional disorder; other specified or unspecified schizophrenia spectrum and other psychotic disorder; schizotypal, schizoid, or paranoid personality disorders; autism spectrum disorder; disorders presenting in childhood with disorganized speech; attention-deficit/hyperactivity disorder; obsessive-compulsive disorder; posttraumatic stress disorder; and traumatic brain injury.
Since the diagnostic criteria for schizophreniform disorder and schizophrenia differ primarily in duration of illness, the discussion of the differential diagnosis of schizophrenia also applies to schizophreniform disorder. 

Brief psychotic disorder. Schizophreniform disorder differs in duration from brief psychotic disorder, which has a duration of less than 1 month.

Residual Schizophrenia is a condition where the patient does not experience the various debilitating symptoms of the condition, and is on the road to recovery. Yet, even in this type of Schizophrenia, the patient will not really show any interest in life and the activities around him or her. Finally, the last type of Schizophrenia is Schizoaffective Disorder which is characterised by the symptoms of Schizophrenia as well as the symptoms of major mood disorders. When combined, this condition can lead to major complications and complex behavior.

A patient suffering from this condition will need to see a mental health specialist like a psychiatrist or a psychologist on an immediate basis. The treatment will be carried out on a long term basis for the results to start appearing.

Schizophrenia - Know the Causes Behind it

Schizophrenia is a psychiatric disorder in which a person s mood, knowledge, thought and several other characteristics gets disturbed. We can notice most of the adults and old people with few symptoms of schizophrenia, which are most commonly left unidentified. The exact cause of schizophrenia is not yet known. The person feels that they are being constantly watched, they feel the presence of someone or something, which is not actually there. They are always suspicious and think that other people are gossiping and thinking about them.

Possible causes of Schizophrenia
Though the exact cause of schizophrenia is not known there are few factors, which contribute to the cause of schizophrenia.

    Genetic factors: People with a family history of schizophrenia are at higher risk of getting schizophrenia.
    Environmental factors: Environmental factors include excessive stress during pregnancy or later stages of life. Several other factors during pregnancy and childhood are responsible for causing schizophrenia. These factors are:
        Decreased oxygen level during delivery due to premature birth or prolonged labour
        Parental loss or separation in early stages of life
        Parental exposure to virus or during infancy
        Childhood physical or sexual abuse
        Abnormal brain structures and brain chemistry

Sings and symptoms of schizophrenia

    Hallucination: To see, feel or hear anything that really does not exist is known as hallucination.
    Delusion: A thought or belief of a person, which is either false or impossible in reality is known as delusion.
    Thought and speech disturbances: The thought process and speech of a schizophrenic will be disorganized, due to which he or she  will fumble or is distracted as they are unable to align their thoughts.
    Difficulty in concentrating: It is difficult for people suffering from schizophrenia to concentrate on the task at hand.
    Erratic behaviour: People suffering from schizophrenia tend to behave erratically, either they will be too jumpy or will be perfectly still for hours at a stretch. Most people belief that those who are suffering from schizophrenia are often violent in nature, which actually is not the case.

Treatment for schizophrenia
Schizophrenia can be treated, if identified at an early stage. . It is best advised to consult a psychiatrist the moment you spot the symptoms. Anti psychotic drugs, self help behaviour change, counselling and rehabilitation are few treatment modalities available for schizophrenia.

Schizophrenia: Can Genetics be the Reason Behind it?

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