Neurological disorders are an enigmatic bunch. There are various ongoing researches to identify the exact cause and how to treat them. While some argue that schizophrenia is a chronic brain disorder, others do not agree with it and debate that the origin is yet to be identified and the factors which produce it are yet to be identified.

Factors supporting it to be a brain disease are listed below.

Scan images (MRI and PET scans) of people who have had schizophrenia are different and have a reduced volume of grey matter, especially in the frontal and temporal lobes. In some people, this loss could be as high as 25%. Serial images have shown that the loss begins in the outer (parietal) region and gradually spreads to the rest of the brain. There is a strong correlation between the extent of this grey matter loss and the severity of the symptoms more the loss, worse the symptoms. Severe symptoms include hearing voices, psychotic thoughts, delusions, hallucinations and severe depression. This grey matter reduction does not depend on whether the person has undergone treatment or not for the condition. 

The counter argument is that grey matter loss is not seen in patients with schizophrenia alone. A number of neurological disorders, including normal ageing, manifest as grey matter loss on the scan images. Also, another consoling news is that this grey matter loss is completely reversible.

The way neurotransmitters respond to stimuli in people with schizophrenia is also slightly different. There are two variations to this debate: that schizophrenia is caused by excessive amounts of dopamine or increased sensitivity to dopamine. There are two proofs for this hypothesis first, dopamine suppressants are useful as antipsychotic drugs and secondly drugs which produce the same effect as dopamine can cause hallucinations similar to those seen in schizophrenics. There could be other neurotransmitters involved too, but the dopamine connection is more strongly established.

The electrical activity of the brain as seen in EEG is very different and abnormal in schizophrenic people. This reduced brain activity is another indication of the fact that schizophrenia is another brain disorder. There is also a strong genetic component to schizophrenia. Family history correlation is also very strong. The correlation extends to the point that where there is a neurologic disorder in the first-degree relatives, the chances of developing schizophrenia is increased.

There are specific genes, mutations of which are also attributed to schizophrenia. While the risk factors are in place (as mentioned above), the environmental conditions (brain infections, head trauma, family/social stressors and toxins can all lead to the manifestation of the symptoms. With medications and support therapy, both prevention and symptom management are possible.

Schizophrenia - Is It Really a Brain Disease?

Genetics is a fascinating subject which has received much attention during present times in the field of medical science as it gives the solutions to many a puzzle. The same applies to the hard to pronounce medical term  schizophrenia  that refers to a mental disorder which disrupts the innate human ability to feel, express, behave, and think clearly.

The condition is a chronic illness, and the disorder may last for years or even a lifetime. Often considered to be the most disabling of mental illnesses, schizophrenia does not refer to multiple or split-personalities. It is more about psychosis where patients become unable to differentiate between reality and fiction.

How does the condition manifest itself?
The symptoms of schizophrenia are rendered into three categories. The positive signs include delusions, hallucination, movement disorders, and dysfunctional, and unusual ways of thought. The negative symptoms include the inability to experience happiness or pleasure in everyday life, reduced talking, and difficulty in sustaining or beginning any activity. While  positive  means exaggerating certain behavior in this context, the term  negative  does not imply bad behavior, but the absence of regular behavior patterns. Then follows the cognitive aspect (the subtlest behavior changes) which includes trouble in paying attention, or problems with using memory, etc.

What could be the possible causes?
There s no specific reason that may cause schizophrenia; however, some factors play an important role in making a person have this mental condition. Various environmental factors are suspected to be responsible for the condition; these may include viral infections, excessive exposure to toxins like marijuana, extreme stress, etc. In some instances, schizophrenia can occur solely due to abnormalities or chemical imbalances in the brain. Experts note that a history of schizophrenia in the family tree can increase the risk of schizophrenia in future generations.

Who can develop schizophrenia?
Schizophrenia can develop at any age. However, it is during the teenage years or the 20s when the condition takes effect. Though rare, it can sometimes invade the minds of children below five years of age.

How can it be treated?
There s no cure available for schizophrenia. However, the periods of recovery from this illness and its symptoms can be reduced through various possible treatments. These include medication and psychosocial therapy, supportive psychotherapy or cognitive behavioral therapy, electroconvulsive therapy, and psychosurgery. The administration of these procedures can reduce the chances of recurrence and relapse. Sometimes hospitalization may become necessary as a part of treatment to stabilize patients that do not have anyone to take care of them at home.

Modern medicine is yet to discover failsafe remedies for schizophrenia. Early diagnosis and treatment can reduce the condition in patients. Hospitalization can reduce the chances of a relapse and can prevent the mental condition from worsening. The moment any sign of schizophrenia is noticed, one is strongly advised to opt for psychological treatment. These actions can help to reduce disruptions in a patient s personal and social life.

Schizophrenia - How Does The Condition Manifests?

Schizophrenia is a severe, chronic mental disorder that affects an individual s ability to think and make decisions, as well as relationships and emotions. The illness is characterized by experiences or unrealistic thoughts, disorganized behaviour and speech, reduced participation in routine activities. A person diagnosed with schizophrenia also experiences difficulty concentrating and memorizing things.

Schizophrenia does not have a definite cure. However, psychological rehabilitation can help the patient manage the symptoms of the illness, and improve the quality of life. This is where psychosocial therapy steps in.

Rehabilitation Psychology for Schizophrenia

Rehabilitation Psychology is a speciality of Psychology that utilizes psychological skills, knowledge, and theories to evaluate and treat people diagnosed with disabilities and chronic health issues in order to maximize functional ability, independence, social participation, and overall health.

A rehabilitation psychologist individualizes services to address different patients with varying health conditions. In order to meet this goal, the discipline adopts a holistic approach and considers individuals within a broad social context.

Different Treatment Approaches

Rehabilitation psychology follows these techniques to address mental disorder like schizophrenia in people  

Individual Psychotherapy   a psychologist/therapist teaches the patient how to deal with their behaviours and thoughts. Patients learn more about the ailment and its effects   and how to distinguish between what is real and what is not. The therapy may also help them manage day-to-day life.

Cognitive Behaviour Therapy   CBT can help the patient change the way they think or behave. A psychologist can show them how to deal with hallucinations and voices. After a couple of CBT sessions, you may be able to identify what triggers psychotic episodes   delusions and hallucinations   and prevent or reduce them.

Cognitive Enhancement Therapy   CET teaches individual ways to recognize triggers, social cues better, and improve memory and attention, and the ability to organize thoughts. The therapy combines group sessions and computer-based brain training.

Social Skills Training aimed towards improving social interactions and communication
Rehabilitation procedures such as problem-solving support and job counselling

Even if the above techniques are able to improve the condition, a schizophrenic person will likely need to continue with special care and education on how to become part of the community. 




How Effective Is Rehabilitation Psychology In Managing Schizophrenia?

Both schizophrenia and autism are considered to be neurological disorders resulting from atypical neural development, occurring due to a variety of causes. Both these disorders have a genetic predisposition that may be due to environmental factors. However, there are a few basic differences between the two disease conditions.

Autism is also known as Autism Spectrum Disorder (ASD), is a neurodevelopmental disorder characterized by a spectrum of abnormal behaviour. They include persistent deficits in social communication and interaction, along with restricted and repetitive patterns of behaviour, interests or activities.

Signs of autism in babies

By 6 months - No social smiles or other warm, joyful expressions; limited to no eye contact
By 9 months - No sharing of vocal sounds
By 12 months - No babbling or use of gestures to communicate; not responding to one s name when called
By 16 months - No use of words
By 24 months - No meaningful or two-word phrases
Signs of autism at any age

Avoids eye contact and wants to be alone
Finds it difficult to understand other people s feelings
Speaks very less or has delayed language development
Echolalia - Repeats words or phrases
Cannot accept change in routine or surroundings
Performs repetitive behaviours like flapping or rocking
Has restricted interests and hobbies
Reacts unusually intense to sounds, smells, tastes, lights, colours etc.
Schizophrenia
Schizophrenia is a neuropsychiatric disorder that begins during late adolescence and early adulthood. It is characterized by delusions, hallucinations, disorganized speech and behavioural changes that cause social and occupational dysfunctions.

Signs of Schizophrenia

The symptoms of schizophrenia are usually observed between ages 16 and 30, such as e.g. delusions, hallucinations, thought disorders, movement disorders etc.
Delusions are false beliefs of the patient that may take many forms like delusions of persecution or grandeur. You may feel somebody is controlling you or may think you have extraordinary powers and abilities.
Hallucinations are when the patient hears voices more than seeing, feeling, tasting or smelling random things, which are not actually there.
Thought disorders are when the person jumps from one subject to another for no logical reason.
Some negative symptoms i.e. these are symptoms which are normally present in a healthy individual, but are absent in a schizophrenic patient. E.g. absence of facial expressions, lack of motivation etc.
Cognitive symptoms affect the individual s thought process. They can be positive or negative based on their expression. E.g. poor  executive functioning  which deals with the ability to understand information and make decisions using them, finding it difficult to focus etc.
Although both Autsim spectrum disorder and schizophrenia are interlinked in their causes and neurological background, the symptoms for each disorder are different. 
Consult your physician if you happen to observe any of these symptoms in your loved ones.

Autism & Schizophrenia - What Is The Difference?

Schizophrenia has been recognized as a mental disorder that combines symptoms like hallucinations with distorted thinking and others like fright and severe paranoia. This condition is one that gets progressively worse over time and leads to delusional thinking. Oversleeping and complaining of fatigue are usually the earliest signs of this condition's onset. Eventually, it becomes a debilitating factor in the life of the patient, who will not be able to function in a normal way due to the severe symptoms.

Read on to know more about the types and causes of this condition:

Genetic Causes: Schizophrenia may be caused due to genetic factors and it may be a learned or inherited disorder. It is known to affect patients who have a parent or a sibling who may have suffered from this condition. Yet, one must also remember that Schizophrenia can only be influenced by genetics, and not determined by the same.
Environmental Causes: When there has been an exposure to a viral infection during the pre natal stage, the patient is susceptible to this condition. Also, it may affect children who have been subject to the loss of a parent or separation at an early age. Physical and emotional abuse in one's childhood may also bring on this condition. Low level of oxygen at the time of birth is one of the causes of this condition in many patients.
Anomalies in Brain Structure: When the brain ventricles of the patient are enlarged, he or she may be prone to this condition. Also, anomalies in the temporal lobes and amygdala have links with the onset of this condition.
Types: A wide variety of mental and medical conditions can manifest with psychotic symptoms that must be considered in the differential diagnosis of schizophreniform disorder. These include psychotic disorder due to another medical condition or its treatment; delirium or major neurocognitive disorder; substance/medication-induced psychotic disorder or delirium; depressive or bipolar disorder with psychotic features; schizoaffective disorder; other specified or unspecified bipolar and related disorder; depressive or bipolar disorder with catatonic features; schizophrenia; brief psychotic disorder; delusional disorder; other specified or unspecified schizophrenia spectrum and other psychotic disorder; schizotypal, schizoid, or paranoid personality disorders; autism spectrum disorder; disorders presenting in childhood with disorganized speech; attention-deficit/hyperactivity disorder; obsessive-compulsive disorder; posttraumatic stress disorder; and traumatic brain injury.
Since the diagnostic criteria for schizophreniform disorder and schizophrenia differ primarily in duration of illness, the discussion of the differential diagnosis of schizophrenia also applies to schizophreniform disorder. 

Brief psychotic disorder. Schizophreniform disorder differs in duration from brief psychotic disorder, which has a duration of less than 1 month.

Residual Schizophrenia is a condition where the patient does not experience the various debilitating symptoms of the condition, and is on the road to recovery. Yet, even in this type of Schizophrenia, the patient will not really show any interest in life and the activities around him or her. Finally, the last type of Schizophrenia is Schizoaffective Disorder which is characterised by the symptoms of Schizophrenia as well as the symptoms of major mood disorders. When combined, this condition can lead to major complications and complex behavior.

A patient suffering from this condition will need to see a mental health specialist like a psychiatrist or a psychologist on an immediate basis. The treatment will be carried out on a long term basis for the results to start appearing.

Schizophrenia - Know the Causes Behind it

Schizophrenia affects over 1% of the world s population and affects the way a person thinks, feels and behaves. In most cases, it is diagnosed when a person is between the ages of 16 to 25. This condition can be hereditary and is said to affect men more often than women. Schizophrenia is characterized by an inability to distinguish between real and imaginary which can lead to delusions, social withdrawal, hallucinations and other forms of social and occupational dysfunction.

Schizophrenia affects different people in different ways. On the basis of the type of symptoms exhibited, this disease has been categorized into 5 sub types. These are:

Paranoid schizophrenia: This type of schizophrenia is characterized by delusions and hallucinations that may make the person exhibit paranoid behaviour. These people often feel like they are being watched or followed and may have delusions of grandeur. They may also get angry quickly on minor issues and show signs of anxiety and hostility.
Disorganized schizophrenia: In such cases, the person may behave in ways that are difficult to understand or speak in broken sentences and have difficulty structuring a sentence. They may also display inappropriate behaviour and react in ways not suitable to the occasion. People suffering from disorganized schizophrenia may also neglect their personal hygiene.
Catatonic schizophrenia: People suffering from catatonic schizophrenia may swing between immobility and periods of rapid movement. They may stay quiet for hours or talk rapidly repeating everything they hear. These people have a high risk of harming themselves as they are usually unable to look after themselves and complete daily activities.
Undifferentiated schizophrenia: People suffering from this type of schizophrenia exhibit behaviour that fits into more than one type of schizophrenia. From time to time they may have hallucinations, suffer from delusions or display catatonic behaviour and disorganized behaviour or speech.
Residual schizophrenia: Even though a person may not be currently showcasing any signs of schizophrenia, they are said to have residual schizophrenia. Such people need to have had at least one schizophrenic episode. These people may exhibit symptoms later or be in complete remission.
With schizophrenia, an early diagnosis can make treatment easier and hence if you notice anyone exhibiting signs of schizophrenia, you must advise them to seek medical help immediately. Schizophrenia cannot be cured but it can be managed with a combination of typical or atypical medication and cognitive therapy. The latter can be in the form of self-help groups, housing and employment programs, counselling and therapy. 

Types Of Schizophrenia - How Can They Be Dealt With?

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