Neurological disorders are an enigmatic bunch. There are various ongoing researches to identify the exact cause and how to treat them. While some argue that schizophrenia is a chronic brain disorder, others do not agree with it and debate that the origin is yet to be identified and the factors which produce it are yet to be identified.

Factors supporting it to be a brain disease are listed below.

Scan images (MRI and PET scans) of people who have had schizophrenia are different and have a reduced volume of grey matter, especially in the frontal and temporal lobes. In some people, this loss could be as high as 25%. Serial images have shown that the loss begins in the outer (parietal) region and gradually spreads to the rest of the brain. There is a strong correlation between the extent of this grey matter loss and the severity of the symptoms more the loss, worse the symptoms. Severe symptoms include hearing voices, psychotic thoughts, delusions, hallucinations and severe depression. This grey matter reduction does not depend on whether the person has undergone treatment or not for the condition. 

The counter argument is that grey matter loss is not seen in patients with schizophrenia alone. A number of neurological disorders, including normal ageing, manifest as grey matter loss on the scan images. Also, another consoling news is that this grey matter loss is completely reversible.

The way neurotransmitters respond to stimuli in people with schizophrenia is also slightly different. There are two variations to this debate: that schizophrenia is caused by excessive amounts of dopamine or increased sensitivity to dopamine. There are two proofs for this hypothesis first, dopamine suppressants are useful as antipsychotic drugs and secondly drugs which produce the same effect as dopamine can cause hallucinations similar to those seen in schizophrenics. There could be other neurotransmitters involved too, but the dopamine connection is more strongly established.

The electrical activity of the brain as seen in EEG is very different and abnormal in schizophrenic people. This reduced brain activity is another indication of the fact that schizophrenia is another brain disorder. There is also a strong genetic component to schizophrenia. Family history correlation is also very strong. The correlation extends to the point that where there is a neurologic disorder in the first-degree relatives, the chances of developing schizophrenia is increased.

There are specific genes, mutations of which are also attributed to schizophrenia. While the risk factors are in place (as mentioned above), the environmental conditions (brain infections, head trauma, family/social stressors and toxins can all lead to the manifestation of the symptoms. With medications and support therapy, both prevention and symptom management are possible.

Schizophrenia - Is It Really a Brain Disease?

When you hear the word  schizophrenia , the first thing that comes to mind are those serial killers shown on the TV or you call it split personality. But that is not the true meaning of it. It is not split personality or some kind of violent illness. Schizophrenia is a severe chronic mental illness which makes it difficult to differentiate between what is real and what is false.

As this is a mental illness, you will not be able to see any changes physically. You need to understand the symptoms of schizophrenia in order to know if a person is suffering from this problem. There are different kinds of symptoms that are used for diagnosing schizophrenia, but they all differ from person to person. Also, the symptoms that you see now, may not be seen later as the disease progresses. There are different types of schizophrenia and each has different symptoms.

Here is a list of the different types of schizophrenia and the most predominant and significant symptoms of each type.

Paranoid Schizophrenia: People suffering from paranoid schizophrenia are characterized by strong auditory hallucinations and of being persecuted. However, they are very normal and function normally. But they are not ready to discuss their feelings openly and the symptoms are not observable. Other symptoms include anger, hostility and disorganized speech.
Disorganized Schizophrenia: As the name suggests, people with disorganized schizophrenia exhibit disorganized thoughts. Delusions and hallucination may not be seen in this type of schizophrenia. The behavior of the affected person is quite disorganized or it is difficult to understand what they are saying. In fact, some emotions exhibited by the affected person are hard to understand or they are not at all relevant to the current situation. Their daily routine and activities will also be affected.
Catatonic Schizophrenia: People with catatonic schizophrenia are characterized by increased or decreased movement. This symptom actually varies from person to person. Some people stay at a place for a long time without any kind of movement and some people keep moving for hours and do not stop. They do not speak for hours and sometimes they keep repeating the same thing over and over again. This has to be treated immediately as they will not be able to manage even their daily routine with this kind of behavior.
Undifferentiated Schizophrenia: Undifferentiated schizophrenia is a condition where the symptoms do not fall into any of the above three types. You will also be able to observe hallucinations, delusions, anger, disorganized speech or catatonic behavior.
Residual Schizophrenia: As the name suggests, it is the residue of schizophrenia behavior, but it is less severe as compared to the past. Delusions, hallucination and disorganized speech may still be present but compared to the past, the patient would be doing better. 

Schizophrenia - 5 Types & Their Signs!

Chronic health disorders like schizophrenia affect not only the patient, but also the life of their care givers. Though schizophrenia can be treated to improve the patient's quality of life, it cannot be cured. Hence, it falls on the care giver's shoulders to watch out for symptoms of this disease and manage the person and their disorder. What should one do in such a case?

1. Educate yourself: the first step towards looking after a person with schizophrenia is to know the symptoms of the disease. With treatment, these may become better or worse so if you notice any change in the symptoms, bring it to your doctors notice at once.

2. Reduce stress: your goal as a schizophrenic person's caregiver should be to give them a calm environment and boost their confidence. Stress has a negative effect on all people and in schizophrenics this effect is much worse. Hence reduce stress and create an effective support system and structured environment for your loved one.

3. Do not ask the patient to change'his reality: when a person is suffering from schizophrenia, you should not force them to change their behaviour and reality, in order to adjust in the society at large. You should rather support the patient to accept his reality, to be at peace, since there is a very strong genetic component involved in its aetiology. Also, it is important that, both the patient and the family in particular should opt for regular counselling sessions.

4. Regular exercise: schizophrenics need not be cooped up in the house all day. Encourage the patient to go outside and exercise regularly. Exercise reduces stress and produces endorphins that make a person feel energized and happy. This should be complemented by a healthy diet. Minimize the amount of carbs and sugar intake and increase the amounts of omega 3 fatty acids in the patient's diet.

5. Join a support group: joining a support group is a very good idea for both the patient and the caregiver. For the patient, this provides a form of social interaction and for the caregiver is a platform to meet people with similar first hand experiences

6. Encourage treatment: convincing a schizophrenic person to seek treatment can be quite challenging. Suggest treating symptoms of the disorder such as insomnia and lack of energy rather than the disease itself to make the patient feel more comfortable. Give the patient options to choose from to make them feel more in control of the situation.

7. Monitor medication: once the treatment has started, ensure that the patient sticks to the prescription. Maintain a regular schedule by using weekly pill boxes and alarms. Also keep an eye on the possible side effects of these medicines. Ensure that your doctor has a complete list of medicines that the patient takes so that there is no chance of medicines interacting negatively with each other.

8. Prepare for crisis situations: it is always a good idea to have an emergency plan in place. Keep emergency contact details of all the doctors and therapists at hand along with the address and phone number of the closest hospital. Share your situation with friends and family so that in case of an emergency, they can be relied upon to take care of your children and other dependants.

Living with Schizophrenia

Schizophrenia is a brain disorder that affects how a person sees the world. Schizophrenia makes it difficult for you to distinguish between what is real or unreal. It can stop you from thinking clearly, handling your emotions properly or functioning in a normal way. However, one can manage schizophrenia effectively. The best way is to recognise the signs and symptoms that one might be having. Here is how you can recognise the symptoms of schizophrenia:

Delusions: A delusion is an idea that a person might have despite there being obvious evidence that it is not true or does not exist. These are extremely common in schizophrenia and occur in ninety percent of the people with this disorder. These delusions can be of many types:
Delusion of persecution: When a person believes that someone is out to get them.
Delusion of reference: a very neutral environmental event tends to have a personal meaning to them. They might think that a person on the TV or a billboard is trying to send a message specifically for them.
Delusion of control: In this, a person believes that his or her actions are being controlled from the outside.
Hallucinations: These are sensations or sounds that a person experiences as real when they only exist in that person s mind. Visual hallucinations are relatively more common. These are only meaningful to the person who is experiencing them. These voices or visuals are usually horrific, vulgar, abusive or critical. They tend to increase in intensity when the person is alone.
Disorganized speech: People who suffer from this order have a hard time maintaining or concentrating on certain thoughts. They may start sentences and forget what they were talking about. They might even go off track in the middle of conversations. People with this disorder usually say illogical things and speak incoherently. A patient may also make up words or phrases that only have a meaning to them.
Disorganized symptoms: A person is unable to take care of himself or herself or their work. They face a decline in their overall daily functioning and their behaviours are bizarre and may have no purpose. People with this disorder cannot control their impulses.
Negative symptoms: This refers to the absence of behaviours that usually appear normal to other people. These include lack of expressing oneself emotionally, lack of interest or enthusiasm. These also include speech difficulties or abnormalities as well as their lack of interest in the world.
Schizophrenia can be caused due to many reasons. These include lack of oxygen during birth, exposure to a virus during infancy, physical or sexual abuse, depression, hereditary components or enlarged brain ventricles. This disorder can affect a patient s mental as well as physical health and can endanger the people around them as well as their relationships. Hence, the signs and symptoms should be recognised as early as possible in order to get the right kind of treatment.

Schizophrenia - How To Recognize The Signs?

Schizophrenia is a psychiatric disorder in which a person s mood, knowledge, thought and several other characteristics gets disturbed. We can notice most of the adults and old people with few symptoms of schizophrenia, which are most commonly left unidentified. The exact cause of schizophrenia is not yet known. The person feels that they are being constantly watched, they feel the presence of someone or something, which is not actually there. They are always suspicious and think that other people are gossiping and thinking about them.

Possible causes of Schizophrenia
Though the exact cause of schizophrenia is not known there are few factors, which contribute to the cause of schizophrenia.

    Genetic factors: People with a family history of schizophrenia are at higher risk of getting schizophrenia.
    Environmental factors: Environmental factors include excessive stress during pregnancy or later stages of life. Several other factors during pregnancy and childhood are responsible for causing schizophrenia. These factors are:
        Decreased oxygen level during delivery due to premature birth or prolonged labour
        Parental loss or separation in early stages of life
        Parental exposure to virus or during infancy
        Childhood physical or sexual abuse
        Abnormal brain structures and brain chemistry

Sings and symptoms of schizophrenia

    Hallucination: To see, feel or hear anything that really does not exist is known as hallucination.
    Delusion: A thought or belief of a person, which is either false or impossible in reality is known as delusion.
    Thought and speech disturbances: The thought process and speech of a schizophrenic will be disorganized, due to which he or she  will fumble or is distracted as they are unable to align their thoughts.
    Difficulty in concentrating: It is difficult for people suffering from schizophrenia to concentrate on the task at hand.
    Erratic behaviour: People suffering from schizophrenia tend to behave erratically, either they will be too jumpy or will be perfectly still for hours at a stretch. Most people belief that those who are suffering from schizophrenia are often violent in nature, which actually is not the case.

Treatment for schizophrenia
Schizophrenia can be treated, if identified at an early stage. . It is best advised to consult a psychiatrist the moment you spot the symptoms. Anti psychotic drugs, self help behaviour change, counselling and rehabilitation are few treatment modalities available for schizophrenia.

Schizophrenia: Can Genetics be the Reason Behind it?

Bipolar disorder:

Also known as manic-depressive disorder, bipolar disorder is the sudden change in mood, which might take a swing from depression to mania. It is a very severe disorder and can bring about unstable and precarious behavior. The risk of having suicidal tendencies is also quite high. Bipolar disorder is usually treated with medicines alongside therapy.

Symptoms:

1. Bipolar mania
2. Hypomania
3. Depression
4. Mood swings

The mood swings do not follow any particular pattern.

Schizophrenia Disorder

Schizophrenia is a chronic mental disorder which affects the general behavior and lifestyle of a person. Schizophrenics might face a difficulty in distinguishing between the real and the imaginary.
Contrary to public belief, schizophrenia is neither split personality nor multiple personalities. It is not an after effect of any previous traumatic experience. It might be genetic or a result of chemical imbalance in the brain chemicals.

Symptoms:

1. Paranoia
2. Senseless talking
3. Feeling apathetic
4. Insomnia
5. Personality change
6. Hallucinations
7. Delusions
8. Withdrawal from society
9. Attention deficit disorder or add

No specific medicine is available for schizophrenia. Usually, rehabilitation is advised to regain confidence and recover skills required for a productive life.

Psychosis

Similar to schizophrenia, psychosis is another mental disorder which is characterized by hallucinations and delusions. Psychosis is extremely dangerous and harmful as it might spur you to cause self-inflicted wounds and pain. It is of utmost importance to consult a doctor immediately after experiencing psychotic symptoms.

Symptoms:

1. Hallucinations
2. Delusions
3. Depression
4. Anxiety
5. Suspicion
6. Insomnia or hypersomnia
7. Withdrawal from society
8. Attention deficit disorder or add
9. Attention deficit hyperactivity disorder or ADHD

The only available diagnosis for psychosis is a psychiatric evaluation. Certain medical tests and x-rays may also be executed along with it to detect the underlying cause. Psychosis may be caused due to Parkinson's disease, Huntington's disease, brain tumors, Alzheimer's disease, epilepsy, etc.

Although there aren't any medical complications in psychosis, it should not be left untreated due to its harmful effects. Medication and therapy are the known cures of psychosis.

Symptoms of Bipolar Disorder, Schizophrenia Disorder and Psychosis

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