Neurological disorders are an enigmatic bunch. There are various ongoing researches to identify the exact cause and how to treat them. While some argue that schizophrenia is a chronic brain disorder, others do not agree with it and debate that the origin is yet to be identified and the factors which produce it are yet to be identified.

Factors supporting it to be a brain disease are listed below.

Scan images (MRI and PET scans) of people who have had schizophrenia are different and have a reduced volume of grey matter, especially in the frontal and temporal lobes. In some people, this loss could be as high as 25%. Serial images have shown that the loss begins in the outer (parietal) region and gradually spreads to the rest of the brain. There is a strong correlation between the extent of this grey matter loss and the severity of the symptoms more the loss, worse the symptoms. Severe symptoms include hearing voices, psychotic thoughts, delusions, hallucinations and severe depression. This grey matter reduction does not depend on whether the person has undergone treatment or not for the condition. 

The counter argument is that grey matter loss is not seen in patients with schizophrenia alone. A number of neurological disorders, including normal ageing, manifest as grey matter loss on the scan images. Also, another consoling news is that this grey matter loss is completely reversible.

The way neurotransmitters respond to stimuli in people with schizophrenia is also slightly different. There are two variations to this debate: that schizophrenia is caused by excessive amounts of dopamine or increased sensitivity to dopamine. There are two proofs for this hypothesis first, dopamine suppressants are useful as antipsychotic drugs and secondly drugs which produce the same effect as dopamine can cause hallucinations similar to those seen in schizophrenics. There could be other neurotransmitters involved too, but the dopamine connection is more strongly established.

The electrical activity of the brain as seen in EEG is very different and abnormal in schizophrenic people. This reduced brain activity is another indication of the fact that schizophrenia is another brain disorder. There is also a strong genetic component to schizophrenia. Family history correlation is also very strong. The correlation extends to the point that where there is a neurologic disorder in the first-degree relatives, the chances of developing schizophrenia is increased.

There are specific genes, mutations of which are also attributed to schizophrenia. While the risk factors are in place (as mentioned above), the environmental conditions (brain infections, head trauma, family/social stressors and toxins can all lead to the manifestation of the symptoms. With medications and support therapy, both prevention and symptom management are possible.

Schizophrenia - Is It Really a Brain Disease?

Bipolar disorder:

Also known as manic-depressive disorder, bipolar disorder is the sudden change in mood, which might take a swing from depression to mania. It is a very severe disorder and can bring about unstable and precarious behavior. The risk of having suicidal tendencies is also quite high. Bipolar disorder is usually treated with medicines alongside therapy.

Symptoms:

1. Bipolar mania
2. Hypomania
3. Depression
4. Mood swings

The mood swings do not follow any particular pattern.

Schizophrenia Disorder

Schizophrenia is a chronic mental disorder which affects the general behavior and lifestyle of a person. Schizophrenics might face a difficulty in distinguishing between the real and the imaginary.
Contrary to public belief, schizophrenia is neither split personality nor multiple personalities. It is not an after effect of any previous traumatic experience. It might be genetic or a result of chemical imbalance in the brain chemicals.

Symptoms:

1. Paranoia
2. Senseless talking
3. Feeling apathetic
4. Insomnia
5. Personality change
6. Hallucinations
7. Delusions
8. Withdrawal from society
9. Attention deficit disorder or add

No specific medicine is available for schizophrenia. Usually, rehabilitation is advised to regain confidence and recover skills required for a productive life.

Psychosis

Similar to schizophrenia, psychosis is another mental disorder which is characterized by hallucinations and delusions. Psychosis is extremely dangerous and harmful as it might spur you to cause self-inflicted wounds and pain. It is of utmost importance to consult a doctor immediately after experiencing psychotic symptoms.

Symptoms:

1. Hallucinations
2. Delusions
3. Depression
4. Anxiety
5. Suspicion
6. Insomnia or hypersomnia
7. Withdrawal from society
8. Attention deficit disorder or add
9. Attention deficit hyperactivity disorder or ADHD

The only available diagnosis for psychosis is a psychiatric evaluation. Certain medical tests and x-rays may also be executed along with it to detect the underlying cause. Psychosis may be caused due to Parkinson's disease, Huntington's disease, brain tumors, Alzheimer's disease, epilepsy, etc.

Although there aren't any medical complications in psychosis, it should not be left untreated due to its harmful effects. Medication and therapy are the known cures of psychosis.

Symptoms of Bipolar Disorder, Schizophrenia Disorder and Psychosis

Genetics is a fascinating subject which has received much attention during present times in the field of medical science as it gives the solutions to many a puzzle. The same applies to the hard to pronounce medical term  schizophrenia  that refers to a mental disorder which disrupts the innate human ability to feel, express, behave, and think clearly.

The condition is a chronic illness, and the disorder may last for years or even a lifetime. Often considered to be the most disabling of mental illnesses, schizophrenia does not refer to multiple or split-personalities. It is more about psychosis where patients become unable to differentiate between reality and fiction.

How does the condition manifest itself?
The symptoms of schizophrenia are rendered into three categories. The positive signs include delusions, hallucination, movement disorders, and dysfunctional, and unusual ways of thought. The negative symptoms include the inability to experience happiness or pleasure in everyday life, reduced talking, and difficulty in sustaining or beginning any activity. While  positive  means exaggerating certain behavior in this context, the term  negative  does not imply bad behavior, but the absence of regular behavior patterns. Then follows the cognitive aspect (the subtlest behavior changes) which includes trouble in paying attention, or problems with using memory, etc.

What could be the possible causes?
There s no specific reason that may cause schizophrenia; however, some factors play an important role in making a person have this mental condition. Various environmental factors are suspected to be responsible for the condition; these may include viral infections, excessive exposure to toxins like marijuana, extreme stress, etc. In some instances, schizophrenia can occur solely due to abnormalities or chemical imbalances in the brain. Experts note that a history of schizophrenia in the family tree can increase the risk of schizophrenia in future generations.

Who can develop schizophrenia?
Schizophrenia can develop at any age. However, it is during the teenage years or the 20s when the condition takes effect. Though rare, it can sometimes invade the minds of children below five years of age.

How can it be treated?
There s no cure available for schizophrenia. However, the periods of recovery from this illness and its symptoms can be reduced through various possible treatments. These include medication and psychosocial therapy, supportive psychotherapy or cognitive behavioral therapy, electroconvulsive therapy, and psychosurgery. The administration of these procedures can reduce the chances of recurrence and relapse. Sometimes hospitalization may become necessary as a part of treatment to stabilize patients that do not have anyone to take care of them at home.

Modern medicine is yet to discover failsafe remedies for schizophrenia. Early diagnosis and treatment can reduce the condition in patients. Hospitalization can reduce the chances of a relapse and can prevent the mental condition from worsening. The moment any sign of schizophrenia is noticed, one is strongly advised to opt for psychological treatment. These actions can help to reduce disruptions in a patient s personal and social life.

Schizophrenia - How Does The Condition Manifests?

Schizophrenia is a mental disorder which is characterized by disturbed mental thoughts in the patient, paranoia, phobias, hallucination, slow dementia and etc. As it is clear from this brief definition, Schizophrenia is a serious mental illness which can leave a patient stranded from performing basic day-to-day activities or even keeping healthy relationships with their close ones. 

Even though there is no particular age where people are vulnerable from suffering from this disease, yet from a common observation and study conducted on the patients, it has been observed that schizophrenia hit men in their early 20 s and early 30 s in case of women. The study also feels that it is impossible for a schizophrenic to be of age younger than 12 or older than 40. According to another study conducted by the universities, the life of a schizophrenic patient is not guaranteed. 

Symptoms of Schizophrenia:

As mentioned above, there is a common pattern in each schizophrenic patient, however, it is next to impossible to diagnose schizophrenia in teenagers since the onset of the disease is symbolized by the patient's constant change of friends or decrease of performance in school, both of which is normal in teen years. Schizophrenics also isolate themselves and become moody which again, is a common instinct of the teenager. However, apart from these, there are other differentiating symptoms as mentioned below which help in the accurate diagnosis of the disease. 

Hallucinating
Delusional
Emotionally dull and disconnected with their loved ones
Negative social life and academic performance
Dementia
Disability of remembering easy-to-learn and remember things
Causes of Schizophrnia

According to the researchers, there are more than one reasons for this disease. Read them all below:

Genetic mutation and inheritance- genetics play an important role in this disease. It needs more than one mutational combination of schizophrenia to happen and that is why it is observed in less than 1% of the population only. Those who have had a family history of schizophrenia are very hard to inherit the disease because patients hardly ever reach the stage of life called marriage. But a family history of psychosis is sure a determining factor. 
Neurotic reason- this reason includes the brain chemistry and important brain chemical such as- dopamine and glutamate.
Drug abuse- it has been revealed that consuming hallucinating and mind-altering drugs during teenage years are greatly responsible for the increase in the number of schizophrenia cases in early 20 s.
Treatment

As it was mentioned above, there is absolutely no way to cure schizophrenia known to man as of yet. However, the only way to approach it medically is by managing its symptoms separately. Such as:

Antipsychotic medication
Psychotherapies Self-help groups
Nursing care

Schizophrenia - What Causes It?

Schizophrenia is a disease of the mind that is usually degenerative in nature. The complex disorder is generally characterized by symptoms, such as delusions, hallucinations (both auditory and visual) and disturbances in speech and is usually chronic in nature. The symptoms are not regular and can appear at any point of time. So it is highly possible that a person suffering from schizophrenia may sometimes bear resemblance to any other normal person and all of a sudden, might exhibit symptoms typical of Schizophrenia.

The causes of Schizophrenia include:

Brain Dysfunction: Abnormalities in the cerebral cortex (the cerebrum s outer covering that is vital in regulating consciousness) of the brain is the most common cause of this disorder. This is due to the presence of abnormally enlarged ventricles in that region. The decreased brain size owing to the enlarged ventricles is often related to the hallucinations and delusions experienced by schizophrenics.
Genetic Factors: Studies have also stated  genetics  to be an important cause behind this disorder. Closer the family ties, higher the risks of transmitting the disorder.
Biochemical Factors: More than one neurotransmitter is being targeted by recent drugs to control schizophrenia.

Symptoms which most people do not experience normally, but are found in people diagnosed with schizophrenia are said to be positive symptoms. They are:

Hallucinations: These are sensory experiences of things that do not exist outside the mind. Hallucinations usually manifest in the form of auditory or visual images.
Delusions: Delusions on the other hand are false beliefs one has about oneself. Delusions are of 3 major types:
Grandeur: Wherein the person imagines himself to be a famous personality
Persecution: The belief that somebody somewhere is plotting against you and the whole world is going to get you.
Control: The belief that a larger force, let s say a witch, a demon or even a duck for that matter is controlling your actions.
These positive symptoms generally respond well to medications.
In addition to this, schizophrenics think and speak differently than the rest of the society. They jump from idea to idea, lose track of speech mid-way and often speak in fragmented and haphazardly joined sentences. They are, in fact, unable to fix their attention on anything in particular.
Examples of the most common negative symptoms include:

The flat effect: The individual basically shows no facial expression and always has a flat emotionless mask on while staring into space. At times, they have inappropriate reactions to situations. Example - they might laugh at somebody's death and cry ad get angry when something good happens. 
Avolition: This condition occurs when the individual just sit for hours doing nothing as well as behaves in a way lacking any motivation or enthusiasm.

Schizophrenia -  Can Biochemical Factors be the Cause Behind it?

Schizophrenia is a debilitating mental and emotional condition that is characterised by a heavily distorted thought process as well as hallucinations and even extreme fear that borders on paranoia. Let us find out more about this debilitating disease:

Causes:
1. Genetics: genetic factors play an important role in the development of schizophrenia.
2. Environment: possible environmental factors include obstetric complications, the mother's exposure to influenza during pregnancy or starvation. It has also been suggested that stress, trauma even migration can lead to the emergence of schizophrenia. 
3. Neurodevelopmental factors: schizophrenia appears to be a neurodevelopmental disorder. That is changes that cause the illness have been occurring from the earliest stages of development even in utero, and may continue to influence the development of the brain over the first 25 years of life. 

Symptoms: 
This disease has a variety of symptoms include cognitive and emotional ones that can vary in the degree and severity. One of the most common symptoms included hallucinations and delusions where the patient may end up imagining things that do not really exist. The patient may also be gripped by sudden and crippling fear like paranoia, which can be debilitating as far as everyday functioning of the person goes. The symptoms can also interfere with the way a person deals with situations and life skills on a cognitive basis. Withdrawal and hopelessness are also a part of this disease.

Treatment: 
The earliest signs and symptoms must be referred to a psychiatrist. The treatment involves the management of the case of an individual basis along with psychological rehabilitation programs and inclusion of the patient in self-help groups. Housing and employment programs must also be availed so as to keep the patient busy. Also, behaviour therapy will be required in such cases. The mode of counselling should usually be on a one on one basis, although many doctors also suggest that group therapy can help in showing examples of progress so as to encourage the patient to change and get a new lease of life.

Schizophrenia: Causes, Symptoms and Treatment

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