Colorectal cancer is otherwise known as cancer of the colon or the rectum. This can affect both men and women with age being a major risk factor. Majority of such cancers are seen to occur after age of 50 years.

Type: colorectal cancers can present as one of the following types: 

Adenocarcinomas are the most common type of colorectal cancers. These cancers begin in the cells making mucous and other fluids. Certain colorectal cancers begin as adenomatous polyps (adenomas) that turn cancerous over a period of time. This is precisely why the adenomas are regarded as pre-cancerous or pre-malignant.

Gastrointestinal (GI) carcinoid tumors, GI stromal tumors, primary colorectal lymphoma, leiomyosarcoma, melanoma & squamous cell carcinoma are certain other colorectal cancers

Carcinoid tumors: start in specialized cells that produce hormones, in the intestine.

GI Stromal tumors: start in the interstitial cells of Cajal (ICC), in the wall of the colon.

Lymphomas: start typically in the lymph nodes but they may also start in colon or rectum.

Sarcomas: can start in the muscle and the connective tissue in the walls of the colon and rectum.

Gender: it affects both male and female populace.

Etiology: mostly, the factors that are associated with increased risk of colorectal cancer include the following  

Age exceeding 50 years.

Racial & ethnic background such as African Americans, in the USA, are known to have the highest incidence of colorectal cancer, and mortality rates.

Low fibre and high fat diet. Excessive consumption of red meat (e.g. goat meat, beef, pork, lamb, or liver), processed meats, butter, refined grains, sweets, sugary drinks etc all can increase the risk of colorectal cancer.

Personal history of inflammatory bowel disease (IBD) (e.g. ulcerative colitis), Crohn s disease, adenomatous colorectal polyps, colorectal cancer etc all.

Family history of colorectal cancer or adenomatous polyps etc all.

Inherited syndromes such as familial adenomatous polyposis (FAP) and Lynch syndrome (hereditary non-polyposis colon cancer or HNPCC).

Sedentary lifestyle/ associated Obesity.

Type 2 diabetes.

Tobacco and alcohol abuse.

Features or symptoms can vary from person to person depending on the size and location of the tumour. Following are the signs & symptoms mainly -

Changes in bowel habits, diarrhea or constipation or an alternating diarrhea and constipation.

Occult/ blood in the stool, and 

Problems related to blood loss (e.g. anemia, weakness, fatigue, intolerance to exercise, shortness of breath, increased heart rate, chest pain etc all),

Abdominal discomfort (frequent gas/ flatulence, bloating, fullness, cramps, and pain), vomiting etc.

Unexplained weight loss,

Pain with bowel movement,

Feeling that bowel does not empty completely,

Stools are narrower than usual.

Diagnosis: Following are the diagnostics employed. Abnormal blood test results may be indicative of malignancy, but a follow-up imaging/ biopsy is always the gold standard for accurate diagnosis.
Blood: fecal occult blood test, Carcinoembryonic Antigen (CEA) assay values are raised, Hb/ RBC counts may be low.
Imaging: Colonoscopy, Endorectal Scan/ CT Scan followed by Biopsy clinches the diagnosis and the nature of the disease.
Apart from the above-mentioned barium enema X-Ray, USG, Chest X-ray, PET CT scan etc all help detect metastasis, if any. An increase in level of the serum tumor marker  CEA  is indicative of metastatic spread/ proliferation that can be ascertained through a PET CT scan.
Treatment: Conventional treatment includes surgery, radiation and chemotherapy as contextually appropriate. Simultaneously, an adjunctive/ integrative naturopathic treatment with suitable complementary & alternative medicines (CAM)/ therapies too can help improve clinical outcomes and facilitate recovery as feasible contextually.
Prognosis: preventive measures, earlier diagnosis and right early treatment is key for better prognosis and efficient/ effective therapeutic management. Usually, the chances of cure for an early stage cancer are more. Above-mentioned apart, recovery chances are influenced by the grade, stage of cancer, recurrence and the patient s general health & vitality etc all too.

Prevention: rightly said, prevention is always a better choice. Although genetic risks are difficult to modify, still an adherence to a Mediterranean diet, maintaining an ideal body weight and an active lifestyle with due emphasis on regular exercising (for at least 30 minutes daily), de-stressing and relaxation is highly recommended for prevention or reducing the risks of colorectal cancer. A healthy eating plate comprises essentially a low fat diet, fibre rich foods including whole grain cereals, green leafy vegetables cooked using healthy vegetable oils, fresh fruits of all colours as seasonally available and healthy proteins/ fats including fresh fish, poultry, beans, nuts etc all. It is advisable to limit milk/ dairy, preferably of low fat content, to 1 to 2 servings max daily. Although alcohol is optional and is not for everyone, the consumption of the same, if any, has to be strictly in moderation, and is best avoided. Smoking is to be avoided as well. Again, red meat, butter, refined grains, sweets, sugary drinks including carbonated beverages and other high calorie foods etc all, if any, are to be taken sparingly or are best avoided too. Apart from the generic preventive measures as mentioned above, certain pre-malignant conditions, of which adenomas are the most common, can be successfully treated with complementary and alternative medicines too.

Colorectal Cancer - In a Nutshell!

The body receives its source of energy and nutrition through the blood, which is the transport medium. The blood runs through a highly complex network of blood vessels, with the aorta being the largest one. It originates in the heart, the left ventricle precisely and supplies oxygenated blood to all parts of the body. Coarctation is a condition where there is a narrowing of the aorta. The heart, therefore, has to exert extra pressure to push out blood so that blood supply to the target organs is not affected.

The exact cause of aortic coarctation is not known, though it often develops at birth and so is known as a congenital disorder. Depending on the severity of the narrowing, symptoms develop at various times in life. While some infants demonstrate symptoms, some may not show any symptoms well into adulthood. Infants with severe narrowing may manifest the below symptoms quite early in life.

Difficulty in breathing may gasp
Difficulty in feeding
Be extremely irritable
Profuse sweating
Pale skin
When these symptoms are not noticed and treated in time, the child may have heart failure or even die. If the symptoms do not manifest early in life, the infant can grow into childhood quite normally. Symptoms may then manifest which would be different, as below.

Increased blood pressure
Headaches (frequent)
Weakness in the muscles
Nosebleeds
Chest pain
Frequent fainting spells
These are generic symptoms and it is difficult to suspect coarctation of the aorta. Therefore, further imaging would be required to rule out coarctation of the aorta. There are some risk factors, most related to the heart, which puts one at increased risk of developing aortic coarctation.

Bicuspid aortic valve
Aortic valve stenosis and/or regurgitation
Mitral valve stenosis and/or regurgitation
Patent ductus arteriosus
Treatment: Diagnosis is the first step in treating coarctation of the aorta. This would include a series of imaging tests including an echocardiogram, electrocardiogram, chest x-ray, CT scan, and MRI.
Surgery is often the most definitive mode of treatment, and the approach chosen depends on the severity and stage of identification. The most common approach is to open up the narrowed portion and keep it from collapsing again, so that blood flow is restored. This is known as a balloon angioplasty and stenting. Some of the other procedures used include:

Resection with end-to-end anastomosis
Bypass graft repair
Subclavian flap aortoplasty
Patch aortoplasty
In all affected individuals, after surgery, medications are prescribed to maintain blood pressure levels, which is often increased. In addition, lifestyle changes including exercise and healthy eating habits have to be developed.

Coarctation of the Aorta - Symptoms and Treatment

When an organ or fatty tissue is squeezed through a hole (weak spot) in the connective tissue or a surrounding muscle then it causes a hernia. Usually, hernia happens at the abdominal wall and sometimes it can be seen as an external bulge.

There are various types of hernia which include:

  Inguinal Hernia (happens in the inner groin).
  Incisional Hernia (develops through a scar or an incision in the abdomen).
  Umbilical Hernia (develops at the belly button).
  Femoral Hernia (develops in the outer groin or upper thigh area).
  Ventral Hernia (develops in the general ventral or abdominal wall).
  Hiatal Hernia (develops inside the abdomen, beside the upper diaphragm or stomach).

The most common cause of hernia is the combination of pressure and opening of connective tissue or weakness of the muscle. Anything that escalates the abdominal pressure can lead to a hernia, including lifting heavy weights, constipation, persistent sneezing or coughing, obesity, and diarrhea. Overexertion, poor nutrition, and smoking can also weaken the muscles and can increase the possibility of a hernia.

Mesh Surgery 
Surgical mesh is used to supply extra support to the damaged or weakened tissue. It is a medical device, usually made out of either animal tissue (from skin or intestine) or synthetic material. Surgical mesh of synthetic material can be made in non-knitted sheet forms or in the knitted mesh. The synthetic material used for making a surgical mesh can be absorbable, non-absorbable material, or a combination of both.

Surgical mesh made out of animal tissue is disinfected and processed in a way that makes it suitable for implantation. These are absorbable and mostly made from the tissues of pig or cow.
Absorbable mesh degrades and loses its strength over time. It is not made to supply
long-term support to the restored site.

On the other hand, non absorbable mesh remains in the body for a long duration and is accounted for as a permanent implant. It provides permanent strength for restoring hernia.

In Hernioplasty or the mesh surgery for a hernia, the muscle opening is not stitched shut, instead it is covered with a sterile, flat mesh which is mostly made of synthetic or animal tissue. Small cuts are made around the hole in the shape of the mesh and the patch is stitched into the healthy surrounding tissues. The weak or damaged tissues around the hernia use the mesh, as support to regrow.

Recovery
Usually it takes up to 4 to 6 weeks to recover completely from mesh surgery. However, one can get back to his/her normal routine within 2 weeks post the surgery. There are certain precautions that one should undertake to avoid any complications. One should avoid heavy weight lifting, heavy exercises, stretching, and running. These precautions include diet modifications too. One should avoid consuming heavy fatty food and meat.

Takeaway
A hernia can be caused by a number of reasons and mesh surgery is a medical procedure helps to treat this problem. One should not avoid the treatment of hernia as the early treatment reduces the complications.

Mesh Surgery For Hernia - All You Must Know!

Ovarian cysts and fertility: Is there a connection?

Having a child is one of the most profound experiences in a woman s life. The joy of being a mother and welcoming a new life is unparalleled. In the midst of such expectation, an inability to conceive can take a serious toll on any woman s health. The mental scars from such an event can never be obliterated.

This does not mean you should give up. Consult a doctor to find the cause and rectify it. With advances in medical science and technologies like IVF in the market, no fertility challenge is insurmountable.

One of the most common cause of infertility is ovarian cysts. According to research conducted by the American Society For Reproductive Medicine, ovarian cysts resulting in ovulation abnormality and infertility has been recorded among 25% of women.

There are two types of cysts that are produced as byproducts of ovulation-

1. Follicular Cysts which does not break open to release the eggs. Rather the follicle stays as a whole while the cyst continues to grow.

2. Corpus Cysts or luteal cysts is a condition when after the egg has bronek free, the follicles seal itself rather than shrinking and the fluid builds up inside.

Causes-

Ovarian cysts are mainly caused due to hormonal imbalance, abnormal cell growth where the cells overgrow and develop into cysts, pelvic infections that spread to the ovaries and fallopian tubes and causes severe harm to them, and endometriosis when the tissue attaches to an ovary and forms cell growth.

Which ovarian cyst affects fertility?

Ovarian cysts that generate complications during pregnancy include-

1. Endometriomas - This is the condition when the tissues lining your uterus or endometrium grows outside the uterus or the fallopian tubes and is largely associated with fertility problems. Endometriomas can differ in sizes from the range of less than an inch to over 6 inches. They are filled with dark coloured blood.

Some studies have demonstrated that women suffering from mild endometriosis develop a lower (2%-4%) chance of getting pregnant each month when compared to women who are healthy and have a 15%-20% chance. Another research states that 40% of unexplained infertility results from endometriosis through anatomical distortion or inflammation.

2. Polycystic Ovary Syndrome - PCOS is the condition where small cysts form inside your ovaries which prompts irregular periods, excessive stomach cramps and large hormonal imbalance. Connected to immature ovaries, they do not assist in ovulation and thus produces complications infertility. The immature follicles with an immature egg cause the ovary to be politic.

This chronic lack of ovulation also alters the hormonal levels in your body that assists in ovulation. Women with PCOS develop high levels of androgen or male hormones in your body, which gets converted to estrogen. As a result, they do not ovulate.

Does the treatment of ovarian cysts also affect fertility?

This usually depends on the kind of treatment you receive. Hormonal birth control doesn t have a long-term effect on fertility. Although surgeries can invariably damage some healthy eggs inside your body, the doctors recommend that the ovaries be removed before you have more complications. However, in both the situations, the egg count in your body decreases significantly.

Ovarian Cysts & Fertility - Is There A Connection?

Cholecystectomy is an operation performed to remove the gallbladder. The gallbladder is a kind of a small sac found just below the liver, on the right hand side of the abdomen. The gallbladder stores a liquid known as bile. Bile is made in the liver and it gets released into the intestine along with the meals. The importance of bile lies in the fact that it helps to digest the fat in foods.
As gallbladder is not really an essential organ, so a child would do well after cholecystectomy. Once the gallbladder gets removed through this pediatric surgery, bile will continue to get released from the liver right into the intestine along with meals.

What is the necessity behind cholecystectomy?
The necessity for performing this surgery of Cholecystectomy can be outlined as follows:

The main reason behind the surgery is gallstones and pain.
Gallstones are small rocks, which form inside the gallbladder
These stones prevent the release of bile out from the gallbladder.
This blockage results in pain as well as jaundice
If a child comes across these problems, he or she would be recommended by his or her primary doctor to visit a paediatrician.
A paediatrician can get rid of the gallstones by removing the gallbladder through performing the surgery if Cholecystectomy.
How is the surgery performed?
The surgery is performed in the following manner:

A Cholecystectomy is performed on most of the occasions by way of laparoscopy.
A small telescope and tiny instruments are placed through very small incisions made on the abdomen.
The surgery normally gets completed within two hours.
When a child gets hospitalized, he or she receives intravenous fluids, antibiotics as well as pain medication.
As and when a child feels well, he/she would be allowed to eat, drink and also take pain relievers through mouth.
Cholecystectomy surgery involves very less loss of blood. Only in a rare case, when there is an emergency, a child needs to receive blood.
Children are released from hospital, one or two days after the surgery as and when they are able to eat, drink and be comfortable about themselves.
Homecare needed after the surgery
There are certain guidelines which parents must follow when their children get back home after the surgery. They include:

Pain management: The pain medication prescribed by the paediatrician is not required at a routine basis after discharge from the hospital. Most of the children only require Acetaminophen (Tylenol) or Ibuprophen once they are at home.
Healing ridge: Once the small incisions get healed, children would be able to feel a firm ridge just below it. It would last for few months, slowly get softened and then disappear.

Cholecystectomy - Know More About It!

Hearing a doctor diagnose you with 'ovarian cysts' can make your mind think of the worst case scenarios, but this is actually quite a common diagnosis. Almost all women are diagnosed with ovarian cysts at some point of their life. The difference lies in the type and size of cyst diagnosed. Hence, before you panic, read up and get informed. However, not everything you read online is trustworthy. Like every other health condition, ovarian cysts are surrounded by a number of myths. Let's debunk five of the most common myths surrounding this condition.

Myth - It requires a surgery 
Contradictory to what you may initially think, not all ovarian cysts are harmful. In most cases, these cysts are small, non cancerous and will be resolved on their own. Surgery is needed only in cases where the cyst is abnormally large or where the cyst is diagnosed as a dermoid cyst or as endometriomas. Hence, if you have been diagnosed with an ovarian cyst find out how big the cyst is and what type of a cyst it is.

Myth - It causes infertility
Being diagnosed with a cyst in your ovaries will not make you infertile or restrict your ability to bear a child. However, it can lead to complications that may cause infertility. If these cysts become infected it could lead to scarring of the fallopian tubes. This is one of the most common causes of infertility. Another situation in which an ovarian cyst may lead to infertility is if it is associated with endometriosis.

Myth - They are cancerous 
With ovarian cysts, every case is unique. However, in most cases, the cysts to not develop into cancerous cells and neither are they cancerous to begin with. A pelvic ultrasound can help your doctor diagnose the type of cyst present in your body. If the doctor deems it cancerous, he or she will usually advise surgery to remove it immediately.

Myth - It only affect women after menopause
A cyst can develop in the ovaries at any stage of a woman's life. A number of women could even develop cysts that they are not aware of. In some cases, women can even develop these cysts post a hysterectomy that does not involve the removal of the ovaries.

Myth - It cannot be controlled
If you suffer from recurrent ovarian cysts, taking birth control pills can help the situation. This can suppress the development of cysts in future. Losing weight if you are overweight or quitting smoking can also lower the risks of developing ovarian cysts.

5 Myths About Ovarian Cysts

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