Our kidneys act as filters which constantly flushes out toxins and excess minerals with water in form of urine. Urine contains lots of minerals which may precipitate and form stones. Urine has lots of pro-precipitating agents and anti-precipitating agents. When their balance disturbs due to some disease, stones start forming. These stones may often lead to abdominal pain which is referred to as renal colic. 

What exactly is renal colic? 

Renal or ureteric colic is the term used for typical pain in one side of abdomen in flank region starting from back and radiating forward towards lower abdomen up to scrotum. This is usually associated with nausea, vomiting and urinary discomfort. There may be blood in urine. 

How kidney stones are related to renal colic? 

Kidney stones usually form inside kidney and lies there without causing any pain. But whenever they are dislodged and stuck at mouth of kidney (pelvis) or anywhere in ureter, they block the passage of urine of that kidney. This causes swelling in kidney termed as hydronephrosis. This swelling in kidney causes renal / ureteric colic. This colic is protective phenomenon and tries to push out the stones. Small stones do come out in urine by this natural process. This spontaneous expulsion of small stones is common and many local practitioners used to get credit of it feigning benefit of their medicine. However large stones need some form of intervention to come out. Otherwise, they do harm to kidneys in long term. 

Symptoms of kidney stones along with renal /ureteric colic - 

Most stones which are lying in calyces of kidney are asymptomatic 
Nausea & vomiting 
Frequent urinary tract infections 
Fever with chills 
Foul smelling urine 
Hesitency, frequency and burning in urination 
Blood in urine (urine with a reddish, pink or brownish hue) 
Passage of small stones in urine 
Treatment of renal colic 

Treatment of ureteric/renal stones involves control of symptoms and stone removal. 

Expectant Treatment or Medical Expulsion Therapy: Small stones of less than 4 mm size usually pass on its own and some medicines like alpha-blockers and steroid hasten up their expulsion. Medium size stone (4-6 mm), sometimes passes with aid of these medications. But stones larger than 6 mm usually require intervention. 
Lithotripsy: This method involves breaking of stones by shock waves into small dusty particles which pass through urine on its own. This is usually suitable for stones upto 1.5 cm and lying in kidneys. This is non-operative treatment which can be done on OPD or Daycare basis. 
Ureteroscopy (URS): This method involves entry of very thin semirigid scope through urethra into ureter. Stone is broken by LASER and removed. This involves single day admission and spinal anaesthesia. 
RIRS- Retrograde Intra Renal Surgery: In this method very thin flexible scope in maneuvered through urethra into the upper ureter and pelvi-calyceal system of kidney. Stones in kidney or upper ureter are broken by LASER and removed. This is also done under anaesthesia and requires a day admission. 
Mini- PCNL: This method is suitable for large renal stones. In this technique, a small hole is made into the kidney through back and tiny scope is entered into the kidney. Stones are broken by LASER and removed. This is done under anaesthesia and require two to three days admission.

Renal Colic - Ways it Can Be Treated?

Glomerulonephritis is a disease that is caused due to inflammation of the small filters that are present within the kidneys or glomeruli. Glomeruli eliminate the excess waste, electrolytes and fluids from the blood, discharged through urine. A glomerular disease can be either acute or chronic. If the condition arises without a combination of any other disease, it is termed as primary glomerulonephritis. Secondary glomerulonephritis is characterized by diabetes or lupus (an auto-immune disorder) being at the root of the disease. Prolonged or severe inflammation can take a toll on the kidneys.


Causes-


Nephrotic syndrome can be primary, being a disease specific to the kidneys, or it can be secondary, being a renal manifestation of a systemic general illness. In all cases, injury to glomeruli is an essential feature. Kidney diseases that affect tubules and interstitium, such as interstitial nephritis, will not cause nephrotic syndrome.


Primary causes of nephrotic syndrome include the following, in approximate order of frequency:
Minimal -change nephropathy
Focal glomerulosclerosis
Membranous nephropathy
Hereditary nephropathies


Secondary causes include the following, again in order of approximate frequency:
Diabetes mellitus
Lupus erythematosus
Viral infections (e.g., hepatitis B, hepatitis C, human immunodeficiency virus [HIV] )
Amyloidosis and paraproteinemias
Preeclampsia
Allo-antibodies from enzyme replacement therapy


Nephrotic- range proteinuria may occur in other kidney diseases, such as IgA nephropathy. In that common glomerular disease, one third of patients may have nephrotic- range proteinuria.


Nephrotic syndrome may occur in persons with sickle cell disease and evolve to renal failure. From a therapeutic perspective, nephrotic syndrome may be classified as steroid sensitive, steroid resistant, steroid dependent, or frequently relapsing.


Treatment-
Whether one is suffering from acute or chronic nephrotic glomerular , with symptoms moderate or severe, the treatment lies in treating high blood pressure and other underlying conditions of the disease.
Water pills help control sweating, thus increasing the fluid flushed from the kidneys.
Statins reduce cholesterol level.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
For kidney failure, dialysis can come to the aid in eliminating excess fluids and regulating hypertension.


Nephrotic Syndrome: Causes and Treatment

At a point when our bodies process the protein we eat, the procedure creates waste products. In kidneys, millions of tiny blood vessels act as filters since they have even tinier holes in them. As blood flows through these vessels, little molecules such as waste items may press through the gaps. These waste items turn out to be a part of the urine. Helpful substances, such as protein and red blood cells are too enormous to go through the gaps in the filter and stay in the blood.

Diabetes and kidneys: Diabetes can harm the kidneys. Abnormal amounts of glucose make the kidneys filter a lot of blood. After a couple of years, they begin to spill and helpful protein is thereby, lost in urine. Having low protein levels in the urine is called micro albuminuria.

Medication: When kidney disease is analyzed on time, during micro albuminuria, a few medications may keep kidney disease from getting worse. Having elevated levels of protein in the urine is called macro albuminuria. When kidney disease is looked up some other time during macro albuminuria, end-stage renal disease (ESRD) usually follows.

Causes: Strain on the organs may cause the kidneys to lose their filtering capacity. Waste items then begin to develop in the blood. Finally, the kidneys start to fail. This failure, ESRD, is intense. A patient with ESRD needs a kidney transplant or a blood filtration by a machine (dialysis).

Other complications: Individuals with diabetes will probably have other kidney-related issues such as bladder infections and nerve damages in the bladder.

Preventing complications: Not everybody with diabetes goes through a kidney disease. Elements that can impact kidney disease improvement include genetics, blood-sugar control and blood pressure. The more a person keeps diabetes and blood pressure under control, the lower the chances of getting a kidney disease.

Keeping your glucose level high can counteract diabetic kidney problems. Research has demonstrated that blood glucose control diminishes the danger of micro albuminuria by 33%. For individuals who suffer from micro albuminuria have now a reduced danger of advancing to macro albuminuria. Different studies have recommended that blood glucose control can reverse micro albuminuria.

Treatment: Essential treatments for kidney infection include control of blood glucose and blood pressure. Blood pressure dramatically affects the rate at which the condition progresses. Indeed, even a gentle increase in blood pressure can rapidly aggravate a kidney infection. Four approaches to bring down your blood pressure are:

Shedding pounds
Eating less salt
Maintaining a strategic distance from liquor and tobacco
Exercising regularly
A low-protein diet can decrease the amount of lost protein in the urine and increase the protein levels in the blood. Never begin a low-protein diet without talking to your physician or nephrologist.

Diabetes & Kidney Problems - Know The Complications!

People with chronic kidney disease notice that their bones tend to get weaker and more slender. They become painful and are bound to break more easily as a consequence of mineral loss. The most common kind of bone infections happen when:

There is a change in the balance between two essential minerals in your body - calcium and phosphate, which prompts loss of calcium from your bones.
Four small glands (parathyroid organs), which regulate calcium in your body, turn out to be excessively active.
There is a change in the way your body utilizes vitamin D, a mineral that is vital for healthy bones.
Every bone disease affects bones in different ways.

Phosphate is found in many food items you eat. Your kidneys normally eject whatever is not required in the body. At the point when your kidneys have stopped functioning properly, phosphate may develop in your blood. Excess phosphate in your blood prompts loss of calcium from your bones, which has a tendency to weaken them. Eating food items that are low in phosphate can keep phosphate from building up in your blood.
Since phosphate stays in your body when your kidneys are no more ready to remove it, four small glands in your neck (parathyroid organs) turn out to be excessively active. When this happens, calcium is expelled from your bones over a long period of time, making them weak.
Vitamin D is a vital vitamin, which affects the balance in the calcium content of your body. Typically, vitamin D is processed into a more soluble state by the kidneys and can be utilized by the body. In case your kidneys have deteriorated, they can no more do this critical job. Luckily, the dynamic type of vitamin D is accessible in the form of medications that can be prescribed by your specialist, if necessary. In case you have a kidney disease, it is vital to find a way to prevent bone illness. Some of the solutions are as follows:
Limit the amount of phosphorus you take in every day. Ask your specialist or dietitian to let you know how much phosphorus you need to have. You can likewise request a list of high-phosphorus food items.
Take a phosphate folio. This is a medicine that you bring with dinners to keep your body from taking in the phosphorus that originates from your food and beverages. This can keep phosphorus from winding up in your blood.
Take a calcitriol supplement. Your kidneys make calcitriol with the help of vitamin D that you get from food and the sun. When your kidneys are not working, they can't make calcitriol. A man-made type of calcitriol can help your body utilize the calcium and phosphorus it needs.
Exercise can make your bones more strong and keep them from breaking.
Try not to smoke or use tobacco. It can aggravate bone disease.
Take your medications the way your specialist instructs you to and do not skip dialysis medicines.
Even after changing your diet and taking medicines, if you still have an excess of phosphorus in your blood, your specialist may propose that you undergo further dialysis.

Kidney Disease - How It Affects Your Bones?

A kidney transplant is a surgical procedure that patients of kidney disease go through in order to replace a non functioning kidney with a live one that is healthy and functions well. Other methods to treat this disease also include dialysis, which basically is an artificial way of doing what our kidneys are designed to do. When dialysis does not work, many doctors recommend a kidney transplant. A replacement or donated kidney can come from a living donor or a non-living donor. This new kidney will mostly work towards keeping the blood clean, which is a function that stops when the old and diseased kidneys fail.
 
So, here's a list of five essential facts that you need to keep in mind if you are looking at a kidney transplant:

1. Donors: While there are living and non-living donors, the doctor will have to ensure that your donor is someone who has no medical history of complications, kidney disease or any other medical condition like diabetes or hypertension. Also, the donor would have to have two proper functioning kidneys. Further, one of the most important factors is the blood group. The blood group of the donor and the patient must match for the transplant to be possible.

2. Procedure: During the surgery, the patient will be under general anesthesia. The surgeon will make an incision in the lower abdomen area and the blood vessels of the new kidney will be connected surgically with the vein and iliac artery of the patient. Thereafter, any excess fluid will be drained before wrapping up the surgery.

3. Rejection: The patient's body may also reject the kidney. The immune system of the patient may mistake the new kidney as an attacking body and its natural defenses may work against it, which will lead to complications. For this, doctors usually prescribe immunosuppressant medicines that will help in preventing such an eventuality. 

4. Longevity: While a living donor's kidney may last longer, a non-living donor's kidney will not enjoy such a long life. In such cases, a second transplant can be conducted.

5. Diet: After the transplant, the patient will be required to go through a number of measures like coughing to show that the lungs are clear, as well as administration of fluids and some amount of examination and dialysis. Also, the patient will have to have a special diet that includes raw fruits and vegetables, and plenty of non-fat dairy ingredients.

A kidney transplant is a major operation that can change your lifestyle in the long run. 

5 Things You Should Know About Kidney Transplant

Kidneys and Kidney Diseases

The kidneys are organs which aim to filter out huge amounts of blood to produce 1-2 quarts of urine. They also perform the task of filtering out the excessive waste materials from the blood stream.

However, there can be cases when infection enters your bloodstream and affects your kidneys. This can cause serious kidney diseases such as cysts, stones and cancer.

Diabetes: What is it and how does it affect your kidneys?

Diabetes is a condition which is caused when the pancreas does not produce enough insulin (Type 1 Diabetes) or when your body doesn t react to the insulin in a normal way (Type 2 Diabetes). The sugar in your food cannot be broken down effectively which can result in problems in your kidneys.

The glucose content in your blood causes considerable damage to the filters in your kidneys. When the filters in the kidney are damaged, a particular protein called albumin releases into your blood and your urine. The damage in the kidneys can affect the kidney function and obstruct the filtering out of wastes from the blood.

Thus, diabetes could be attributed as a major cause of kidney disease.

Managing Diabetes-

Managing diabetes is crucial to avoid kidney diseases. However, diabetes doesn t have a proper cure which is why it is even more important to take care of your health in such cases.

Here are a few ways in which diabetic patients can aim to be healthy and prevent kidney diseases:

Quit Smoking: Smoking increases diabetic complications such as nerve damage and heart strokes which can in-turn affect your kidneys  functions adversely. Hence, it is advisable to quit smoking to keep diabetes under control.

Healthy Meals: Opt for healthy meals which are balanced and packed with nutrients as they help in increasing the insulin function in your body. Foods such as green leafy vegetables, legumes, fruits and lean meat should be included in your meals.

Engage in Physical Exercise: A diabetic person needs to engage in physical exercise in order to maintain a healthy lifestyle. Obesity can increase your chances of complications and can be detrimental to your kidneys as well.

How Does Managing Diabetes Help Your Kidneys?

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