What are the different types of sickle cell disease?

Sickle cell disease or sickle cell disorder is a term often used to talk about a group of diseases affecting hemoglobin. It is the oxygen-carrying element of blood that makes up 2 alpha globins and 2 beta globins. Sickle cell disease happens due to beta-globin mutation and depending on the abnormality in mutation.

Types-
Sickle cell diseases can be of many types depending on the gene mutation in the blood. Some of the common types are-

Sickle hemoglobin s disease (ss)
Hemoglobin ss disease or sickle cell anemia is the most popular type of scd. It takes place when hemoglobin s gene mutation is inherited from both mother and father. In simple words, it happens when the child inherits one substitution beta-globin gene from each parent. In this type, the body only produces hemoglobin s. It is mostly found in people of african and indian origin.

Sickle hemoglobin- c disease (sc):
Patients with sickle hemoglobin sc disease have a moderately dissimilar swapping in their genes of beta-globin. Here, both hemoglobin c and hemoglobin s are inherited from each parent. It may cause similar symptoms like anemia but remains relatively l. People of west african and mediterranean origin are more prone to this.

Hbs beta-thalassemia
People with this type of scd inherit one sickle cell gene s and one gene for beta-thalassemia from each parent. Zero and plus are the two common types of beta-thalassemia. While beta 0 thalassemia usually takes a severe form, beta + thalassemia is a milder form of the disease.

Sickle beta-zero thalassemia
Beta-zero thalassemia takes form when the child inherits the beta s gene from one parent and beta 0 thalassemia gene mutation from the other. With similar symptoms to anemia, it is a slightly severe form of beta-thalassemia.

Sickle beta-plus thalassemia
Substitutions in both beta-globin genes take place in patients with sickle beta thalassemia (sb) disease. This may even lead to the requirement of blood transfusion if no normal beta globin is produced. Mediterranean and caribbean people are more likely to have this disorder.

Hemoglobin sd, hemoglobin se, and hemoglobin so
These are the few rare and not less common types of sickle cell diseases. They are also less severe. People with these forms of scd inherit one sickle cell gene s and one gene from uncommon hemoglobin (d, e, or o) from each parent.

Sickle cell trait
Hbas
People with sct have one sickle cell gene s and one normal gene a from both mother and father. Ones with this disorder show few to no signs of the disease and usually spend a normal life. However, the risk to their future generations still exists.
 

What Are The Different Types Of Sickle Cell Disease?

World hepatitis day is observed on july 28th every year to raise awareness about hepatitis disease among people. It is organized on the occasion of the birthday of Dr. Baruch blumberg who found the hepatitis b virus in the year 1967 and also developed a vaccine for it. Moreover, this day educates everyone about hepatitis infections, the efforts to fight viral hepatitis, and methods people can use for its prevention.

What is viral hepatitis?

Viral hepatitis or hepatitis disease is a condition of inflammation in the liver that leads to severe liver disease and hepatocellular cancer. With deaths happening every 30 secs from a hepatitis-related infection, it is important to treat viral hepatitis at the earliest. Hepatitis is of different types depending on the infection. 

 ;

Types

Viral hepatitis impacts millions worldwide, resulting in both acute and chronic diseases. There are five major classifications of viral hepatitis-

 


	
	Hepatitis a- it is a liver infection that can be prevented by a vaccine. It is a result of the infection as a result of the hepatitis a virus.
	
	
	Hepatitis b- it is an infection that happens due to the hepatitis b virus. It is spread through the blood or other bodily fluids of a person.
	
	
	Hepatitis c- it is a liver infection caused by the hepatitis c virus. It transmits through the blood of a person who is infected.
	
	
	Hepatitis d- delta hepatitis is another name for this virus and the hepatitis d virus is responsible for this. It happens to only those who are already hepatitis b infected. ;
	
	
	Hepatitis e- it is a liver infection resulting from a hepatitis e infection. It is usually found in a person s stool.
	


 

Symptoms

Hepatitis is a condition where you don t show symptoms till it is chronic and starts affecting your liver health. However, people in the initial stages of hepatitis infection might start reflecting symptoms. Some common symptoms of viral hepatitis are:

 ;


	
	Flu-like signs
	
	
	Darker urine color
	
	
	Fatigue
	
	
	Abdominal cramps and pain
	
	
	Appetite loss
	
	
	Weight loss
	
	
	Yellow skin
	
	
	Pale eyes
	


 

People at risk

The risk of catching a hepatitis infection is high in individuals working around these environments-

 ;


	
	Direct contact with hepatitis a infected person
	
	
	Male in sexual relation with another male
	
	
	Drugs abuser
	
	
	Ones with clotting factor disorder
	
	
	Who work with primates
	


 

World Hepatitis Day: Know All About The Disease

The world celebrates world blood donor day on the 14th of june to raise awareness of the need for safe blood and blood products and to thank voluntary and unpaid blood donors for their life-saving gift of blood. 

Importance of blood donation

The importance of donating blood is not only to save the lives of thousands of people who are deprived of life but also to save the lives of many more who are affected by the various diseases. ;

 

It has also been seen that when people; e have donated their blood, they have gained many health benefits as it helps in weight loss, helps maintain healthy liver and iron levels, it helps reduce the risk of heart attack and cancer. ;

 

A blood donation can save a life of- ;


	
	Victims of natural disasters, including earthquakes
	
	
	Patients with hemophilia, sickle cell disease, or cancer
	
	
	People who suffer traumatic injuries from being in a car accident
	
	
	Surgery patients
	
	
	Shooting or stabbing victims
	
	
	Women who suffer complications during childbirth
	


 

Blood types that are needed most

It s good to donate if you re healthy. However, there s always a need for specific blood and plasma which are universal and can be used when a patient blood type is unknown. For newborn infants or if a patient's particular blood type is unavailable.

 ;


	
	Type o negative blood is always needed because it can be used in patients regardless of their blood type.
	
	
	Type ab positive plasma can also be transfused to patients with other blood types. 
	


 ;

Donations are constantly needed

Because of their short shelf life of 5 days after being collected, platelet donations are constantly by the blood blank. Red blood cells also have a short shelf life and needed to be used within 42 days after the collection. Cryoprecipitate and plasma can be frozen and stored for up to a year after donation.


 

Some misconceptions about blood donations


	
	The donor will not experience any kind of pain while donating. ;
	
	
	There will be no scarcity of blood in the body after donating the blood as even after the donation the body will have a surplus quantity of blood. 
	
	
	The common misconception everyone has is that they will faint after donating their blood. ;
	
	
	You will be able to resume your everyday activity immediately after donating the blood. 
	
	
	You will not get infected with aids if you donate your blood. ;
	


 

Donating blood is a great way to give back to your community and potentially save a life by only giving up an hour of your time.

World Blood Donor Day: How Can We Save Life By Donating Blood?

We often forget to take note of things that could cause a spike in blood pressure levels like sleep apnea, ;high sugar intake, among others.

What Are The Things That Could Spike Your Blood Pressure Levels?

Yoga can cure numerous common ailments like asthma and arthritis if practised frequently. Yoga cannot cure diabetes, yet it is helpful in controlling the glucose in the body to a great level. There are different yoga asanas that are cures for lower back pain and acid reflux. Here is how yoga cures some common ailments:

 

Asthma: the main practical cure for asthma lies in yoga. Inhalers can spare your life when you get an asthma attack; however, for a long-term cure, you need to rehearse pranayam and anulom-vulom.

Diabetes: it is one of the most common illnesses on the planet. You cannot generally cure insulin resistance; however, some yoga asanas like the triangle posture (trikonasana) can control your glucose levels.

Heart disease: bhujangasana or cobra pose stretches the chest, massaging organs inside, including heart, and allowing more blood flow to it, thus stimulating and strengthening the heart muscle. Kapalbhati pranayama is also very good for the heart since it increases the absorption of oxygen in the blood. Yoga is proven to be an excellent heart risk improvement practice according to current research too.

Thyroid disorders: yoga asanas like shoulder stand, inverted pose, plough pose, and the fish pose all help in making the thyroid gland work optimally again. The cobra pose and ujjayi pranayama also work wonders by re-balancing metabolism and working on the throat reflex pathways to cure thyroid imbalance. ;

Headache: migraine and headaches are frequently brought on by insufficient blood supply to the brain. Attempt the yoga postures like shirsasana or a headstand to cure headaches or migraines as opposed to taking medicines.

Back pain or lower back pain: it has turned into a common condition among the working class and individuals even undergo surgery to stop the pain. Attempt yoga postures like tadasana or the tree posture.

Joint inflammation or arthritis: arthritis is an ailment that causes serious joint pain. However, yoga can control the amount of pain brought on because of joint inflammation. Attempt the surya namaskar as a flexible approach to cure arthritis.

Liver problems: liver issues can go from minor ingestion to extreme greasy liver disorder. To keep your liver sound, try some extremely basic yoga postures that may increase the blood circulation in the belly. The stretching posture is a great illustration.

Depression: yoga is one of the best and most powerful cures for depression. If you would prefer not to be reliant on antidepressants and dozing pills, attempt yoga asanas like uttanasana.

Polycystic ovaries syndrome (pcos): it is one of the most common problems that are troubling young women nowadays. The side effects are irregular periods, and it can even lead to infertility. So attempt yoga postures like the body stance to cure ovarian cysts without medications or surgery.

 

10 Diseases You Can Cure With Yoga

Blood donation is a procedure carried out for the noble cause of helping patients and saving lives. As the healthy donor's blood is transfused into the patient, it gives them a new life. That said, the donor has to fulfill a few criteria to be eligible to donate blood.

Eligibility

While any healthy adult of any gender can donate blood, it is advised for males to donate once every three months and for females to donate once every four months. Some of the other criteria are-


	
	Age
	


Any person in the age group of 18 to 65 years can donate blood depending on other factors.


	
	Weight
	


A donor should be at least weigh 45 kilograms in order to be eligible.


	
	Pulse
	


The temperature and pulse of the donor should be normal during the time of blood donation.


	
	Hemoglobin
	


Hemoglobin in the blood should be at least 12.5 grams otherwise the donor stands ineligible.


	
	Childbirth
	


A female donor should have delivered at least 1 year ago and stopped lactation.


	
	Blood pressure
	


Ensuring that the systolic and diastolic pressures are within normal limits is a must.


	
	Malaria
	


One should not have malarial symptoms and not have been treated for the same in the last 3 months.


	
	Tattoo
	


A person should not have had a tattoo in the past 12 months.


	
	Immunization and vaccination
	


A donor should not have had shots for cholera, typhoid, diphtheria, tetanus, or plague in the last 15 days.


	
	Cancer
	


A person should be checked for cancer and should not have any signs of cancer in the body.


	
	Infection
	


There should not be hepatitis b, c, tuberculosis, leprosy, or hiv infection in the body.


	
	Diseases
	


A person should not have epilepsy, bleeding disorders, sickle cell, or thalassemia.


	
	Drugs
	


One cannot donate blood if injected intravenously ever. It may cause risk to the recipient.


	
	Heart issues
	


A person willing to donate cannot have any heart disease.


	
	Diabetes
	


People on oral drugs or dieting to control diabetes can donate blood while patients with insulin injections cannot.

 

Strictly prohibited


	
	Ones who have been tested hiv positive.
	
	
	People suffering from cardiac problems, hypertension, cancer, epilepsy, or kidney ailments.
	
	
	Donors who have consumed alcohol in the past 24 hours.
	
	
	Ones with a major dental procedure done in the last one month.
	
	
	Women with miscarriages in the past 6 months.
	



 ;

Know Eligibility Rules For Donating Blood

Don't wait any longer, manage your Psychopharmacologist online with a Lybrate doctor today

Consult for Psychopharmacologist - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES