Brain metastases from systemic cancer are the most common type of intracranial neoplasm in adults, being almost 10 times more common than primary malignant brain tumors, which cause a significant burden on the management of patients with advanced cancer (1). The lungs represent one of the most frequent sources of metastases to the brain, with a probability of (36 64%) (3). Symptoms suffered by the patients include headaches, epilepsy, focal weakness, numbness or changes in mental status. The prognosis of patients with brain metastases is not optimistic and the median survival time is  1 2 months if left untreated. The 1-year survival rate has been recorded as 10.4% (4,5). The treatment of metastatic brain tumors is complex; not only due to being able to provide local control and improve neurological function, but also due to factors such as age, performance and systemic disease status and the size, volume, location and number of metastases at presentation

CyberKnife is a robotic radiosurgery system with a linear particle accelerator (linac), which is coupled with real-time imaging to track and compensate for the patient s or target s motion. As a relatively non-invasive treatment modality, CyberKnife demonstrates certain benefits, including a more accurate target localization and improved dose delivery for the management of metastatic brain tumors that allows higher biologically effective dose delivery without increased incidence of toxicity.

In the present case, the results for the treatment of multiple brain metastases after CyberKnife surgery with a 7 8 Gy marginal dose was promising. CyberKnife for metastatic brain tumors is an effective and safe method for reducing the marginal dose prescribed for multiple brain metastases and for minimizing the radiation-related neurotoxicities. In conclusion, CyberKnife, a focused, highly-targeted radiosurgery and fractionated radiotherapy is particularly useful for multiple brain metastases. CyberKnife provides the advantage of the management of local recurrence and a tolerable complication rate. Although the treatment of brain metastases has been performed with CyberKnife, the clinical significance and optimal dose fractionation scheme require further investigation.

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CyberKnife Therapy Of 24 Multiple Brain Metastases From Lung Cancer!

The prostate gland in males surrounds the urethra, through which urine and sperm are passed out of the body. Its function is to secrete a fluid, which provides nourishment to the sperm. It is about the shape of a walnut and is present between the pubic bone and the rectum.

As a man crosses 40, the prostate gland begins to increase in size due to an increase in the number of cells. This is known as hyperplasia.  The condition is usually benign and therefore the name benign prostate hyperplasia (BPH). As it continues to grow, there is an increased pressure on the urethra. Therefore, there can be problems with urination. The bladder, being a muscular organ, compensates to some extent and so the problems with urination are mostly managed. If left untreated, this can continue to be a major problem and the bladder may not be able to compensate. In men who are 60-plus, BPH is very common.

Signs and symptoms 

One of the initial symptoms of BPH is when the urine stream begins to grow weak.
There could also be a reduced speed of passing urine.
Men with BPH never have a feeling of complete emptying of the bladder.
On the other hand, there is also a constant difficulty in initiating a urine stream. There could be intermittent breaks in the urine stream.
The person may feel the need to strain to initiate the stream and to ensure complete emptying.
There could be dribbling of urine after passing urine.
The duration between two bathroom visits can constantly reduce, with the constant urge to urinate.
There is a constant urge to visit the bathroom, which is more common in the night. One of the most annoying features of BPH is the walking up at night to urinate, but with an inability to initiate a stream and an inability to completely empty the bladder, it leaves the person very irritated and frustrated.
There could be blood in the urine. In fact, blood in the urine accompanied by fever, chills, nausea and vomiting are indications of an emergency.
There could be blockage of urine completely, if the enlargement is quite severe.
Diagnosis
If you are having any of these symptoms, then the doctor will first test for an enlarged prostate through a digital rectal exam. Then a test is done to check a chemical called prostate specific antigen.  Increased levels of this chemical is almost always indicative of BPH. In addition, X-rays and scanning may be used to confirm diagnosis. 

Treatment
Though medications are available, confirmatory treatment is through surgical removal. The procedure needs a inimum of 2 to 3 days.

Enlarged Prostate - 10 Warning Signs To Watch Out For

Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. These abnormal cells do not carry out the functions of normal lung cells and do not develop into healthy lung tissue. As they grow, the abnormal cells can form tumors and interfere with the functioning of the lung, which provides oxygen to the body via the blood.

Lung cancer is the most common cause of death due to cancer in both men and women throughout the world. According to the U.S. National Cancer Institute, approximately one out of every 14 men and women in the U.S. is diagnosed with cancer of the lung at some point in their lifetime. Lung cancer is predominantly a disease of the elderly; almost 70% of people diagnosed with lung cancer are over 65 years of age, while less than 3% of lung cancers occur in people under 45 years of age.

What Causes Lung Cancer?

The development of lung cancer is strongly associated with cigarette smoking, approximately 90% of lung cancers are attributable to use of tobacco. Pipe and cigar smoking can also cause lung cancer, but the risk is not as high as with cigarette smoking. Tobacco smoke contains more than 4,000 chemical compounds, many of which are cancer causing (carcinogens). Passive smoking, i.e. the inhalation of tobacco smoke by non-smokers who live or work with smokers, is also an established risk factor for the development of lung cancer.

Genetic susceptibility (i.e. family history) may play a role in the development of lung cancer. Other causes of lung cancer include air pollution (from vehicles, industry, and power generation) and inhalation of asbestos fibres (usually in the workplace).

Lung Cancer Symptoms

Early symptoms and signs of lung cancer

There may be no symptoms at the onset of the disease. When present, common symptoms of lung cancer may include:

Coughing: This includes a persistent cough that doesn't go away or changes to a chronic smoker's cough, such as more coughing or pain.
Coughing up blood: Coughing up blood or rust-colored sputum (spit or phlegm) should always be discussed with your doctor.
Breathing Difficulties: Shortness of breath, wheezing or noisy breathing (called stridor) may all be signs of lung cancer.
Loss of Appetite: Many cancers cause changes in appetite, which may lead to unintended weight loss.
Fatigue: It is common to feel weak or excessively tired.
Recurring infections: Recurring infections, like bronchitis or pneumonia, may be one of the signs of lung cancer.
Signs of advanced stages of lung cancer

Advanced stages of lung cancer are often characterized by the spread of cancer to distant sites in the body. This may affect the bones, liver or brain. As other parts of the body are affected, new lung cancer symptoms may develop, including:

Bone pain
Swelling of the face, arms or neck
Headaches, dizziness or limbs that become weak or numb
Jaundice
Lumps in the neck or collar-bone region
Treatment

Treatment for cancer involves a combination of surgery to remove cancer cells, chemotherapy and radiation therapy to kill cancer cells. Lung cancer is incurable unless complete surgical removal of the tumour cells can be achieved. Surgery is the most effective treatment for lung cancer, but only a few percentage of lung cancers are suitable for surgery i.e. Stage I and II NSCLC and cancer that has not spread beyond the lung.

Radiation therapy may be used for both NSCLC and SCLC and is a good option for people who are not suitable for surgery or who refuse surgery. Chemotherapy is used for both NSCLC and SCLC. Chemotherapy drugs may be given alone or in combination with surgery or radiation therapy. Chemotherapy is the treatment of first choice for SCLC since it has usually spread extensively in the body by the time it has been diagnosed.

Also used in the treatment of lung cancer are targeted therapies. These are drugs (gefitinib and erlotinib) or antibodies (cetuximab, bevacizumab) that block the growth and spread of cancer by interfering with specific molecules involved in tumor growth and progression. They are used in some patients with NSCLC that does not respond to standard chemotherapy.

Lung Cancer: Causes, Symptoms and Treatments

Skin cancer most often develops on skin that has faced sun exposure. At the same time, it can also affect skin areas that haven't been exposed to sun's rays. Do you know, skin cancer can be prevented by consuming some foods? Yes, and there are some out there:

1. Fatty fish - Including fatty fish in your diet can shield you against melanoma as they contain the beneficial nutrient Omega-3 fatty acids. In fact, these kinds of fatty acids are considered to be best for consumption as unlike saturated fats, they don't increase your risk for certain types of cancer. A study in the International Journal of Epidemiology reveals that individuals who consume a diet containing fish that is high in these healthy fats have low rates of this form of cancer.
2. Vegetables - This is another food option that is known to possess strong skin cancer-fighting properties. Dark leafy veggies like spinach, kale and broccoli can aid fighting against melanoma. A pigment found in tomatoes called lycopene has properties that guard you against cardiovascular diseases as well as cancers of all kinds. Similarly, the pigment carotenoids found in vegetables like carrots, sweet potatoes, etc are known to protect against sunburn.
3. Herbs - Including herbs in your diet can help in replenishing the minerals and vitamins that get depleted due to the action of the sun. According to experts, about 80% of your body's vitamin levels see a reduction when you stay under the sun for 30-45 minutes. Basil, parsley, and rosemary are a few of the herbs that possess cancer-fighting qualities.
4. Flaxseeds - The unique qualities of flaxseed make it the best option against skin cancer. It contains both antioxidants and omega 3 fatty acids, making it an all-around solution to fighting skin cancer.

4 Foods That Help Fight Skin Cancer

Lung cancer is caused by disorderly growth of uncommon cells which line the air passage, usually starting off in a single or both lungs. The irregular cells do not mature into healthy lung tissue but instead divide speedily and result in tumor formation.

Causes behind lung cancer:

Smoking: This is considered as the most significant source of lung cancer. As reported by multiple researches and studies, cigarettes contain over 4,000 chemicals, most of which are cancer causing agents. Active smoking is one of the major causes of lung cancer but what may come to you as a surprise is that extended periods of passive smoking is also a major factor.
Pollution and Exposure: There is high risk of lung cancer development when there is occupational exposure to pollution by chemicals released from industrial factories. Chemical exposure of this kind refers to prolonged exposure over quite few months or years. Some examples of these chemicals are asbestos, diesel exhaust among many others.
Radioactive Gas: Radioactive gases naturally occur in small masses present in all soils and rocks. However, if you breathe in radioactive gases your lungs will damage and may cause the development of abnormal tissue which can cause lung cancer.
Family history: A family history of cancer, especially lung cancer will also put you at high risk of developing lung cancer.
Treatment methods of lung cancer:

Chemotherapy: Chemotherapy is a method in which drugs are injected through veins in your arm (intravenously) or orally or in a combination of both. These drugs kill cancer cells and help to stop it from spreading any further as well.
Clinical Trials: These trials are experimental lung cancer treatment studies. You may have to try out this clinical therapy if other treatment methods aren t working and only if you are accepted into it.
Surgery: A surgeon will help remove affected areas of the lung including cancerous tumors via surgery. The surgeon may need to remove parts of the lung along with the cancerous growth. In certain cases, one side of the lung may also be completely removed to stop the spread of the malignant tissue.
Radiation Therapy: This is a therapy where high energy electromagnetic waves are passed through your body to destroy cancer cells with the help of high-powered energy beams.
Can you prevent lung cancer?

Nutrition -- A  healthy diet with lots of fruits and vegetables may also help reduce your risk of lung cancer. Some evidence suggests that a diet high in fruits and vegetables may help protect against lung cancer in both smokers and non-smokers. But any positive effect of fruits and vegetables on lung cancer risk would be much less than the increased risk from smoking.
Exercise -- Even moderate amounts of exercise can aid in lung cancer prevention. Studies suggest that even something as simple as gardening twice a week is associated with a lower risk of developing lung cancer.
Smoking Habits -- If you stop smoking before a cancer develops, your damaged lung tissue gradually starts to repair itself. No matter what your age or how long you ve smoked, quitting may lower your risk of lung cancer and help you live longer. 
Avoidance of Air Pollution -- Long-term exposure to ambient air pollution and, in particular, particulate matter with absorbed polycyclic aromatic hydrocarbons and other genotoxic chemicals has been suspected to increase the risk for lung cancer. So, avoid air pollution as much as possible.

Lung Cancer - Ways You Can Prevent It!

World Cancer Day, organized by the Union for International Cancer Control (UICC) and celebrated each year on 4 February, is an opportunity to rally the international community to end the injustice of preventable suffering from cancer.
Cancer is one of the worst diseases, which kills millions of people across the world. While there is a wide range of treatment options available, the best way to deal with it is to ensure a good diet along with a healthy lifestyle. Here is a list of cancer-fighting food products, which can immensely help to prevent cancer.

Green vegetables: Leafy green vegetables have multiple health benefits. They are not only rich in minerals, vitamins, enzymes, and antioxidants, but also have very low content of calories, toxins, and sodium. Being antiviral and antibacterial in nature, green vegetables can successfully inactivate carcinogens, halt metastasis and pause the formation of a tumour. Certain vegetables contain isothiocyanates that can detox the cells. Some of the vegetables that are mighty effective in countering cancer cells include kale, romaine, watercress, nutritious, spinach, collard greens etc.
Berries: Berries are one of the best antioxidants among all food items, owing to their high ORAC score. Their antiviral and anti-fungal nature of berries is extremely healthy for the body. Moreover, abundant supply of vitamin A and C makes berries a perfect agent for increasing body immunity. Free radicals are one of the top reasons for metastasis. The proanthocyanidin content of berries helps the body to get a hang of free radicals, thereby decreasing the chances of cancer cells to grow rapidly. They can be consumed daily with any meals.
Spices and herbs: There are a lot of herbs and spices, which boost the immune system and prevents cancer cells to grow further. Turmeric, for instance, is scientifically proved to be a great agent for reducing tumor size and effectively countering breast cancer and colon cancer. Some of the other herbs and spices include black pepper, ginger, raw garlic, parsley, oregano, and basil. They can be consumed daily in the form of juice or along with regular meals.
Organic meat: Many scientists are of the view that organic meat does wonder in a cancer diet. Liver of beef and chicken has high B12 content and helps to remove harmful toxins from the digestive tract and liver. They can balance hormone, digest fat and counter the side effects of triglycerides, drugs, and obesity. This can be included in the diet every alternate day.
Seeds and nuts: Flax seeds and chia seeds are few nutrient-power packed foods in the world. They should be included in the diet due to high fiber, mineral, and fatty acid content. Some other healthy seeds that can pay rich dividends in fighting cancer include walnut, sprouted bean, sunflower seeds etc. Nuts and seeds with all their nutritional qualities can successfully stop metastasis, reduce tumor size and increase immunity in the body, if consumed daily.

World Cancer Day - 5 Amazing Foods That Help Fight Cancer!

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