Problems with the arteries and veins present in the hands or legs can lead to vascular disorders. The arteries carry blood from the heart to other parts of the body in order to deliver nutrients and oxygen. The veins carry the blood back to the heart, after the nutrients have been used up. If these blood vessels of the arteries or veins become blocked or narrowed, it can lead to a vascular blockage.

A vascular blockage that occurs in the hands or legs comes under the category of Peripheral Artery Disease or PAD. These type of disorders are less common in the upper extremities of the arms or hands than in the lower extremities of legs. Few of the signs for the same are:

Pain and difficulty in movement due to decreased blood flow
Numbness or weakness of leg or fingertips
Sores on the toes or feet
If the blockage is deep, symptoms of redness, swelling, extreme pain or cramping can be experienced
Abnormal color changes in the fingertips
Ulcers or wounds that don t heal
Skin sensitivity problems when in cold temperatures
How can it be diagnosed?
The blockage can be detected by various methods namely-

Physical Examination   Your doctor may find decreased pulse at armpit, wrist or fingers, full veins, masses, wounds or gangrene.
Doppler or Ultrasound examination to determine the blood flow in the arteries and veins
MRI Scan of the affected area to pay special attention to the blood vessels
Cold Stress Test
Arteriography to show clear blood vessel details
Angiography to map blockages and narrowing of the arteries
What are the Risk Factors for Peripheral Artery Disease?
An individual is at risk for developing vascular blockages in the hands or legs if one or more of the following factors are present:

Smoking
Diabetes
Heredity Factors   A personal or family history of blood vessel disease
High blood pressure
High cholesterol
Aging   People aged above 50 years and older are more prone to vascular blockage
Can it be treated?
Treatments for vascular blockage can vary depending on the age, cause of the blockage, intensity and overall well-being.

Treatments can include:

Self-care   Reducing risk factors and making lifestyle changes to quit smoking, sedentary life or diabetes, blood pressure and cholesterol management can reverse symptoms of vascular disease.
Medications   A variety of drugs can be prescribed to lower the risk and progression of narrowing blood vessels or prevent blood clotting.
Interventional Procedures   Minimally invasive surgery like saloon angioplasty, stenting or removal of artery plaque build-up.
Surgery   If the blockage is severe, surgery may be performed to lessen the vessel narrowing, reconstruct the artery or tie it off, depending on the circumstances.

Pain in the Hands or Legs!

Top tips to help you fight anxiety

Anxiety is the latest problem affecting a majority of the population, owing to our hectic and fast-paced lifestyles. All of us are so busy in our lives that we forget to provide our mind and body with the basic care that they need in order to function effectively. Here are five useful tips to help you overcome anxiety, on a daily basis.

1. Maintain the right diet
Though it may sound like a cliche, maintaining a healthy diet on a regular basis is the key to beating anxiety. Try and consume food products rich in Vitamin b which is known to improve mental health; and Omega-3s which can effectively counter severe anxiety and depression.

2. Get adequate sleep
Not getting enough sleep not only affects your mind but has an adverse effect on your body as well. Even anxiety can result in irregular sleep patterns and thus ensure that in any situation, you manage to get six to seven hours of sleep on a daily basis.

3. Engage with people
Man is indeed a social animal. People make us happy. The hormone oxytocin significantly reduces anxiety levels and it is released during the process of socializing; thus it is essential to be in contact with your close group of people.

4. Keep your immediate environment clean
A cluttered home or workplace not only adds to physical clutter but contributes towards building up mental clutter as well. Spend a few minutes every day in keeping your immediate environment clean and organized. You are bound to feel calmer and more relaxed.

5. Indulge in breathing exercises
When your brain is tensed, your breathing pattern automatically becomes short and shallow. In order to send relaxing signals to your brain, try taking deep and long breaths and continue the process for a few minutes.

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5 Most Effective Ways To Drive Anxiety Out Of Your Life

Alzheimer's disease is a neurological problem that is characterised by a cognitive decline and memory loss. It is a type of neurodegenerative dementia. The symptoms of alzheimer's disease include not being able to absorb and retain new information, lack of reasoning and judging, not being able to take on complex tasks, impaired visuospatial abilities, problems in reading, writing and speech, among many others. If a person has at least two of these symptoms in a debilitating manner, then the diagnosis can be made in favour of alzheimer's disease. The main causes of alzheimer's are shrinkage of the brain size and death of the brain cells. The immune system is also said to trigger this neurodegenerative disease. Let us find out what medical science has found so far.

1. Connections: many a times, in alzheimer's disease, the memory and behaviour of the person changes because the brain is unable to make proper neural connections which can lead to memory loss of how a person behaved and the elements that formed the basis of the patient's cognition. Apparently, the immune system behaves in the same way within the brain and blocks the connection. This happens because there is constant communication between the brain and immune system along neurological lines, which is where the disease first emanates.

2. Inflammation: the brain is prone to inflammation or swelling that is not the normal kind. This inflammation happens as a result of the activation of the infection fighting neurotransmitters and the chemical changes that happen in the brain when an infection strikes. The inflammation usually happens in the plaques or clumps which the brain tries to protect. These clumps are made up of a protein called amyloid. The immune system is responsible for creating this inflammation in the brain of the patient.

3. Pattern recognition receptors: many of these receptors work in different manners and cooperate with each other to create a response in the brain. These prrs can be found in the brain plaques, and they develop the signs of danger which further fuels the inflammation in the brain as a matter of protection.

4. Activation of cells linked with the immune system: when the prrs begin to respond, it basically activates the immune system and the cells of the same. This is the basic reaction that causes the changes in brain which then leads to the attachment of the protein to the tissue that is diseased, in which case alzheimer's disease starts. The inflammation that we had spoken about earlier basically happens in the nervous tissue.

It is important to recognise and act on the initial signs of alzheimer's disease before it progresses beyond one's control.

Can the Immune System Trigger Alzheimer's Disease

We all have those days when we seem to have hit an all time low. We feel bad, sad, mad, and there seems to be no light at the end of the tunnel. However, this is a temporary, passing phase for most of us. But for people with depression, this is not the case.

Chronic depression, which is more common in women than men, can arise due to different reasons. Major life changes, marital issues, relationship issues, financial problems, chronic medical problems, death of loved ones, life stressors, weather changes, etc. can lead to depression.

This leads to prolonged periods of sadness, feeling of emptiness, loss of interest in activities which were normally pleasurable, irritability, sleeplessness, loss of appetite, weight gain, worthless and hopeless feeling, and feeling of doom. This can result in dejection, social withdrawal, poor performance at work/school, and an overall declining quality of life.

In most cases, there is usually a past, unpleasant experience which leads to depression. This could be different for different people, depending on their tolerance. While some may go into depression over minor relationship issues, for others, it could be as severe as sexual abuse in the past.

Ayurveda recognizes  sadhaka agni  as a fire that helps a person to digest trauma. People with a strong sadhaka agni have a higher tolerance and take more time to get depressed compared to people who have a weak fire in them.

The following are some simple changes that can be very useful in overcoming depression.

Meditate for about 20 minutes every day.
Realize and practice detachment. Most people with depression have a loss of something they were closely attached to. Realizing that nothing in life is permanent and letting it go will play a major role in feeling better.
Get a sound, restful sleep. Stick to a routine by going to bed and getting up at the same time every day.
Walk out in the sun and get a good dose of sunlight. Add exercise to sun exposure to feel elated and upbeat about life in general.
Exercises such as yoga, walking, and cycling also are useful in improving overall balance and health. A healthy and fitter body definitely leaves one in a better mood.
Eat healthy food. Avoid packaged, canned, and processed food. Include a lot of nuts and seeds in your diet, be it roasted or soaked.
Try mood uplifting food items like black pepper, dry ginger, turmeric, amla, cloves, and cardamom.
Herbs like ashwagandha, shatavari, brahmi are highly useful in curing depression. They also treat fluid balance, govern energy and creativity in the body, improve metabolism, and clear toxins.
Ayurveda believes in not just making one feel better, but improving his/her overall well-being by getting to the root of the issue.

Depression - 8 Steps To Help You Get Rid Of It!

Are you aware of the schizophrenia and the adverse effects it inflicts on a person? Schizophrenia is a chronic and extremely severe mental disorder that affects how a person thinks, behaves, and feels. Schizophrenia patients seem like they are not aware of reality. The condition requires lifelong treatment, even after the symptoms leave. There are various types of treatments, which are used for schizophrenic patients. The treatment is usually guided by an experienced psychiatrist. 

The various modes of treatments are as follows:
Medications: Medications are very important for the treatment of schizophrenia, and antipsychotic drugs are most commonly used. They help in managing the symptoms by affecting dopamine. Treatment using antipsychotic drugs aims at managing the symptoms effectively. Antidepressants and anti-anxiety drugs are also used for treatment. Several weeks are required for these medicines to show results. Most of the medications used for schizophrenia treatment are associated with severe side effects and are thus avoided by many people. The patient s cooperation with treatment determines the choice of drug.

First generation antipsychotics: These medicines are associated with adverse neurological side effects, such as the possibility of developing tardive dyskinesia, which is an irreversible movement disorder.
Second generation antipsychotics: These medicines are preferred because of the lower risk of adverse side effects on the body than first generation medicines.
Psychological interventions: When the patient s psychosis decreases, psychological and psychosocial interventions are required. They include the following:

Individual therapy: Psychotherapy is important for normalizing a patient s regular thought patterns. Learning about ways to deal with stress, and identifying warning signs can help patients manage their condition better.
Social skills training: This aims at improving a schizophrenic person s social interactions, communication and his/her ability to take part in daily activities.
Family therapy: Family therapy is important for educating the families of schizophrenic patients about the disorder, and let them know about the ways to deal with it.
Vocational rehabilitation and supported employments: Most people with schizophrenia need some kind of daily living support. Programs are offered by several communities and self-help groups for helping schizophrenic people with housing, jobs, crisis situations. With proper treatment, most schizophrenic people manage to deal with their symptoms and illness.

Hospitalization: During emergency or crisis periods of extreme symptoms, a patient may need to be hospitalized to get proper nutrition, basic hygiene, sufficient sleep, and safety.
Electroconvulsive therapy or ECT is carried out for schizophrenic patients who do not respond to drug treatment. This therapy is also beneficial for patients who have got depression. It is recommended for you to consult a doctor on experiencing any symptom of schizophrenia.


Schizophrenia - Different Modes Of Treatment That Are Followed!

Neurological disorders are an enigmatic bunch. There are various ongoing researches to identify the exact cause and how to treat them. While some argue that schizophrenia is a chronic brain disorder, others do not agree with it and debate that the origin is yet to be identified and the factors which produce it are yet to be identified.

Factors supporting it to be a brain disease are listed below.

Scan images (MRI and PET scans) of people who have had schizophrenia are different and have a reduced volume of grey matter, especially in the frontal and temporal lobes. In some people, this loss could be as high as 25%. Serial images have shown that the loss begins in the outer (parietal) region and gradually spreads to the rest of the brain. There is a strong correlation between the extent of this grey matter loss and the severity of the symptoms more the loss, worse the symptoms. Severe symptoms include hearing voices, psychotic thoughts, delusions, hallucinations and severe depression. This grey matter reduction does not depend on whether the person has undergone treatment or not for the condition. 

The counter argument is that grey matter loss is not seen in patients with schizophrenia alone. A number of neurological disorders, including normal ageing, manifest as grey matter loss on the scan images. Also, another consoling news is that this grey matter loss is completely reversible.

The way neurotransmitters respond to stimuli in people with schizophrenia is also slightly different. There are two variations to this debate: that schizophrenia is caused by excessive amounts of dopamine or increased sensitivity to dopamine. There are two proofs for this hypothesis first, dopamine suppressants are useful as antipsychotic drugs and secondly drugs which produce the same effect as dopamine can cause hallucinations similar to those seen in schizophrenics. There could be other neurotransmitters involved too, but the dopamine connection is more strongly established.

The electrical activity of the brain as seen in EEG is very different and abnormal in schizophrenic people. This reduced brain activity is another indication of the fact that schizophrenia is another brain disorder. There is also a strong genetic component to schizophrenia. Family history correlation is also very strong. The correlation extends to the point that where there is a neurologic disorder in the first-degree relatives, the chances of developing schizophrenia is increased.

There are specific genes, mutations of which are also attributed to schizophrenia. While the risk factors are in place (as mentioned above), the environmental conditions (brain infections, head trauma, family/social stressors and toxins can all lead to the manifestation of the symptoms. With medications and support therapy, both prevention and symptom management are possible.

Schizophrenia - Is It Really a Brain Disease?

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