Hypothyroidism is a condition in which the thyroid gland is not producing the thyroid hormones adequately. This is a fairly common condition.

What is thyroid gland?

The thyroid gland is a small butterfly-shaped gland located just below Adam s apple. It encircles the windpipe or the trachea. It is about 4 cms in height and weighs about 18 gms. This gland is responsible for the secretion of thyroid hormones. Hormones are chemicals produced by special glands like thyroid, adrenals, ovaries etc. They act as messengers and are carried by the blood to the various target organs.

What are the hormones produced by thyroid gland and what do they do?

The thyroid hormones are of two types   T3 (Tri iodo thyronine) and T4 (Thyroxine). These hormones are mainly responsible for the body s metabolism - a process in which food is converted into energy in the cells. They influence growth and development and regulate various bodily functions which are mentioned below:

Heartbeat
Body temperature
Breathing
Body weight
Metabolism of fat
Menstrual cycles in females
Functioning of Nervous system
Digestion
Burning calories etc.
What is Hypothyroidism?

Inadequate production of hormones by the thyroid gland is termed as hypothyroidism. This is also called Underactive thyroid state. Hypothyroidism can make the body s development to slow down and reduces metabolism rates.

What are the causes of Hypothyroidism?

Hypothyroidism can be caused by a number of factors:

Hashimoto's thyroiditis: This is the commonest cause. This is an autoimmune disorder (normally body s defence system fight against external infections. In autoimmune disorder the defence system attacks the healthy cells of the body by mistake). In Hashimoto s thyroiditis the immune system/defence system produces antibodies that attack the thyroid gland and destroy it.
Iodine deficiency in diet. For the production of thyroid hormones iodine is very important. The body does not produce iodine normally, so it needs to be supplemented from outside. Iodine is mainly present in the food we eat. It is mainly present in shellfish, salt-water fish, eggs, dairy products. If a person does not eat iodine rich foods, he may end up with iodine deficiency leading to hypothyroidism. Currently, this causative factor is on the decline due to government initiative of table salt with iodine.
Surgery: Surgery to remove thyroid gland (for e.g. thyroid cancer treatment, overactive thyroid etc.)
Radiation to the neck (to treat cancer in the neck area): The thyroid gland cells are damaged due to the radiation.
Treatment with radioactive iodine: This treatment is used for managing hyperthyroidism/overactive thyroid, where the thyroid gland produces excessive thyroid hormones. One of the treatment modalities is by radioactive iodine. Sometimes this radiotherapy destroys normal functioning cells which lead to hypothyroidism.
Certain medicines: Certain medicines used to treat heart conditions, cancer, psychiatric conditions etc.   for e.g. amiodarone, lithium, interleukin-2, interferon-alpha.
Pregnancy: Pregnancy (the reason is unclear but it has been noticed that the thyroid may get inflamed after delivery   this is called Postpartum thyroiditis.
Damage to the pituitary gland: Pituitary gland is a gland which is present in the brain. It produces a hormone called TSH (Thyroxine-Stimulating hormone).The TSH tells the thyroid gland how much thyroid hormone it should make. If the levels of thyroid hormone in the blood are low, then the TSH will stimulate the thyroid gland to produce more Thyroid hormone.
Hypothalamus disorders: This is an organ in the brain. This produces a hormone called TRH (Thyrotropin Releasing Hormone) which acts on the Pituitary gland to secrete TSH. So any disorder of Pituitary gland will indirectly effect the production and secretion of Thyroid hormones. These are very rare disorders.
Congenital thyroid defects: Some babies are born with thyroid problems. This is due to the thyroid not being developed normally during pregnancy. Sometimes the thyroid gland does not function normal. This can be identified by screening for thyroid disorders in the first week after delivery. This is usually by a blood test using a small drop of blood from the baby s heel.
What are the different types of hypothyroidism?

One classification is based on whether the defect is with the thyroid gland or not:

Primary hypothyroidism: The problem is in the thyroid gland itself and thus there is reduced production /secretion of thyroid hormones.
Secondary hypothyroidism: Here the problem is with the Pituitary gland or the Hypothalamus. This results in abnormal production of TSH or TRH, which indirectly leads to less production and secretion of thyroid hormones.
Another classification is based on the symptoms and levels of the thyroid hormones and TSH:

Overt hypothyroidism: Here the patient is having the symptoms. Further the T3/T4 are low and TSH is high
Subclinical hypothyroidism: Here patient may or may not have symptoms. The T3/T4 levels are normal but TSH is high. In this situation the patient is at an increased risk of developing overt hypothyroidism in the future especially if he has Thyroid peroxidase antibodies on testing.
Who are at risk of developing Hypothyroidism?

Women have a higher risk of suffering from hypothyroidism than men.
Older people are at increased risk.
People suffering from other autoimmune diseases like Coeliac disease, Type-1 Diabetes Mellitus, Vitiligo, Pernicious anemia, Multiple sclerosis, Rheumatoid arthritis, Addison s disease etc.
People with psychiatric conditions such as bipolar disorder
People with Chromosomal abnormalities like Down syndrome, Turners syndrome also have a high risk of suffering from hypothyroidism.
What are the symptoms of hypothyroidism?

Symptoms vary from person to person. They may also mimic other conditions and hence be difficult to diagnose. Symptoms may also develop very slowly over a span of moths-years. Some of the characteristic symptoms of this disease are:

Depression
Constipation
Hair loss
Dry hair
Dryness of the skin
Tiredness
Body pains
Fluid retention in the body
Irregular menstrual cycle
Increased sensitivity to cold
Reduced heart rate
Increase in size of the thyroid gland   called Goitre. This is due to constant stimulation of the thyroid gland by TSH.
Weight gain
Carpal tunnel syndrome
Hoarse voice
Infertility
Loss of libido/sex drive
Confusion or memory problems especially in the elderly
What are the symptoms to look for in a baby if you suspect hypothyroidism?

Infants suffering from congenital hypothyroidism may show no symptoms or exhibit signs of excessive drowsiness, cold hands, cold feet, constipation, hoarse cry, poor growth or absent growth, poor appetite, bloating of abdomen, puffiness of face, swollen tongue, persistent jaundice.

How to diagnose hypothyroidism?

Blood tests:

TSH: This hormone is made in the pituitary gland and it stimulates the thyroid gland to produce thyroxine. If the thyroxine levels are low in the blood, the pituitary gland produces and secretes more TSH into the blood to act on the thyroid gland to produce more thyroxine. A raised TSH level indicates hypothyroidism. Other tests are not usually necessary unless a rare cause of hypothyroidism.
T4: A low level of thyroxine indicates hypothyroidism.
T3: these levels are generally not needed to diagnose hypothyroidism
Anti-Thyroid peroxidase antibodies (anti-TPO antibodies) or Anti- thyroglobulin antibodies are present in 90-95% of patient with autoimmune thyroiditis.
Other blood tests include Creatinine Kinase, Serum Lipids, Complete blood picture etc.
Ultrasound of the neck is done if the patient presents with a thyroid swelling.
What is the treatment of hypothyroidism?

Overt hypothyroidism is treated by synthetic Thyroxin hormone which should be taken every day on an empty stomach at least 30   45 minutes before breakfast. The treatment is continued for the rest of the patient s life. Regular thyroid function tests are done once every 8 weeks-12 weeks to adjust the dose of the thyroxine in the initial period of diagnosis. Once the thyroxine dose is stabilised, the tests can be done even once a year. This treatment is quite effective.

Sub-clinical hypothyroidism is only treated if the patient is a woman and is contemplating pregnancy, in patients with symptoms or if the TSH is quite high.

What are the side-effects of thyroxine medication?

There are few side effects if any. Most people tolerate these medications quite well. An important consideration before starting medication is to check if the patient has chest pain/angina. These people are started on the least available dose. If these patients are started on a higher dose they notice a worsening of their angina pains.

Side effects mainly occur if the thyroxine dose is high which leads to hyperthyroidism. The symptoms of this could be palpitations 9increased heart beat), weight loss, profuse sweating, anxiety, irritability etc.

There are some tablets which increase with thyroxine tablets. These include carbamazepine, iron supplements, calcium supplements, rifampicin, phenytoin, warfarin etc.

What are the complications of hypothyroidism?

If untreated hypothyroidism can lead to:

heart problems like heart attack due to increased levels of bad cholesterol like LDL, or heart failure due to fluid retention
obesity
infertility
joint pains
depression
A pregnant woman with hypothyroidism is at increased risk of giving birth to a baby with congenital hypothyroidism, also known as cretinism. Further, the woman may have pregnancy related complications like pre-eclampsia, premature delivery, low birth weight baby, anemia, post-partum haemorrhage (bleeding after delivery) etc.
Myxoedema is another complication where the patient has extremely low levels of thyroid hormone. The body temperature drops drastically making the person lose consciousness or go into a coma.
References:

2013 ETA Guideline: Management of Subclinical Hypothyroidism; European Thyroid Association (Nov 2013)
Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee; British Thyroid Association (2015)
The diagnosis and management of primary hypothyroidism; Royal College of Physicians and others (June 2011)
Suh S, Kim DK; Subclinical Hypothyroidism and Cardiovascular Disease. Endocrinology Metabolism (Seoul). 2015 Aug 4.
UK Guidelines for the Use of Thyroid Function Tests; British Thyroid Association (2006)
Gaitonde DY, Rowley KD, Sweeney LB; Hypothyroidism: an update. American Family Physician. 2012 Aug 1 86(3):244-51.
Bindra A, Braunstein GD; Thyroiditis. American Family Physician. 2006 May 15 73(10):1769-76.
Wilson GR, Curry RW Jr; Subclinical thyroid disease. American Family Physician. 2005 Oct 15 72(8):1517-24.
British National Formulary; NICE Evidence Services (UK access only)
Baumgartner C, Blum MR, Rodondi N; Subclinical hypothyroidism: summary of evidence in 2014. Swiss Medical Weekly. 2014 Dec 23 144:w14058. doi: 10.4414/smw.2014.14058. eCollection 2014.

Know Everything About Hypothyroidism

Eczema is a skin condition which is characterized by rough, cracked, red, itchy and inflamed skin. Sometimes it can also cause blisters. Eczema is also known as atopic dermatitis. It is a severe condition which starts during infancy and can go on throughout childhood. While some people may outgrow this condition, the rest might have it till adulthood.

Causes of Eczema:
1. Irritants- Certain irritants found in vegetables, meats, juices extracted from fresh fruits, disinfectants, shampoos, detergents and soaps can cause eczema.
2. Allergens- Dandruff, mold, pollens, pets and dust mites can also contribute to Eczema.
3. Microbes- Certain bacteria such as Staphylococcus Aureus, fungi and viruses can also cause eczema
4. Food products- Many people are allergic to food products such as wheat, soy products, seeds, nuts, eggs and dairy products. This might contribute to Eczema.
5. Stress- This doesn t cause eczema but can aggravate the symptoms of it.
6. Hormones- Women usually experience worsening of Eczema during certain stages of their menstrual cycle or during pregnancy.

Symptoms of eczema in infants and children:
1. Rashes appearing on the cheeks and scalp
2. Rashes which bubble up before fluid discharge
3. Rashes which cause itchiness and lead to disturbed sleeping; continuous scratching and rubbing can result in skin infections
4. Rashes which can appear behind the creases of the knees and the elbows; these rashes are also common on the legs, creases of the buttocks, ankles, wrists and neck.

Symptoms of Eczema in adults:
1. Rashes on the nape of the neck
2. Rashes on the eyes, face and neck
3. Rashes that can cause extremely dry skin
4. Extreme discomfort caused due to itching
5. Scaly skin caused due to rashes
6. Rashes which can result in skin infections
7. Lichenification, a condition wherein the rashes thicken and develop knots, is also a possibility.

How is Eczema treated?
1. Topical ointments and corticosteroid creams- These are anti-inflammatory medications which relieve symptoms of eczema such as itchiness and skin inflammation.
2. Antibiotics- These are usually prescribed if there is any underlying bacterial skin infection.
3. Antihistamines- These mainly reduce scratching at night. In some cases, it can also cause drowsiness.
4. Topical calcineurin inhibitors- This is a drug that suppresses activities of the immune system. It helps to prevent flare-ups and decrease inflammation.
5. Barrier repair moisturizers- These types of moisturizers repair the skin and reduce water loss from the skin.

Eczema - 5 Ways It Can Be Treated!

Gallstone Pancreatitis is the result of a blockage in the pancreatic duct by a gallstone. Due to the blockage in the pancreatic duct, inflammation occurs and causes the problem to begin.

This can be a life-threatening situation and should be immediately checked. If the stones from the gallbladder travel down the common bile duct and get stuck at the sphincter, it can stop the outflow of all materials from the pancreas as well as the liver and become quite severe. There are a lot of risks involved when a person suffers from this issue. Rapid weight loss, high cholesterol levels, diabetes are a few of the risks of the disease.

Symptoms of Gallstone Pancreatitis
There are a number of symptoms like pangs of pain in the upper left abdomen and the back, swollen and tender abdomen, vomiting and nausea, increase in the heart rate, fever and more can be seen in a patient suffering from gallstone pancreatitis. Any individual who notices any of the following symptoms should get themselves checked immediately. Any pain in the upper abdominal area can be aggravated by eating foods which are high in fat as well.

Diagnosis of Gallstone Pancreatitis
In order to be completely sure about having gallstone pancreatitis, a number of tests are performed. Blood tests are followed by abdominal CAT scan to check for the inflammation of the pancreas. This also shows how severe the inflammation of the pancreas is. Sometimes abdominal ultrasound is also suggested as CAT scans are sometimes not as sensitive in identifying the problem. Once the problem has been detected, immediate treatment is recommended by doctors.

The Treatment of Gallstone Pancreatitis
The best treatment for pancreatitis is done in the initial stage of the problem. By avoiding taking in liquids and solid food up until the inflammation subsides is one of the best treatments. If the inflammation is relatively modest, the swelling can reduce in a few days by intravenous delivery of fluids for a couple of days.

1. If a CAT scan or MRI of abdomen suggest that a stone in present in the Common bile Duct (CBD), the an Endoscopic treatment referred as ERCP (endoscopic retrograde cholangio-pancreatography) is done. 

2. After the acute pancreatitis episode settles down, patient must undergo a Gall Bladder removal surgery. This is done as gall bladder is the factory of gall stones and patient is at-risk to another episode of Acute Pancreatitis.

In case of severe inflammation, fever and persisting pain, intravenous delivery of food should continue if oral intake of food does not start within 5 to 7 days. Anti-nausea medications are used to treat severe nausea and vomiting along with nasogastric tube. In certain cases, it is important to remove the gallstones from the bladder immediately while in some cases doctors suggest waiting for a period of 24-48 hours before starting the removal procedure. Sometimes a surgical removal of the gallstones is also required but only if the stones do not pass out of the system on their own.

All You Need to Know About Gallstone Pancreatitis

Eczema is not a disease per se, but is a name given collectively to a group of medical conditions, which can cause the skin to become inflamed and irritated. Atopic dermatitis is one of the most common types of eczema.

Causes

While the exact cause of eczema is not known, the most commonly attributed reason is an increasingly sensitive immune system. The overactive immune system produces antibodies, which cause these skin reactions. It is also noted that people with allergies including hay fever and asthma are more likely to develop eczema.

Other conditions which can lead to eczema include allergic dermatitis, irritant dermatitis, stasis dermatitis, scabies, fungal infections, xerotic dermatitis, lichen planus and scalp infections.

There is also a genetic predisposition, and children whose parents have had eczema are likely to develop eczema.

Symptoms

In most people, eczema is present in the form of small blisters, which are filled with fluid and can ooze. Gradually, there could be dryness, crusting, scaling and thickening of the skin with plaque formation. The most common symptom would be itching. The different types of eczema as noted above would have diagnostic features. For instance, when testing for irritant or contact dermatitis, there would be an irritant that is causing this. Stasis dermatitis would have circulatory issues and often affects the lower legs.

In fair-skinned people, these lesions begin as red and then turn brown. There also could be lightening of the affected skin area in people with slightly darker skin.

Diagnosis

For a trained medical eye, diagnosis of eczema is not a tough task. A complete physical examination may be done to assess the extent of eczema spread. Blood tests may be done to test for allergies. In very rare cases, a biopsy may also be required.

Treatment

The goal of treatment is to reduce itching and improve moisturization. Eczema, unless associated with an infection, is not contagious.

Using copious amounts of creams and lotions help in improving hydration and moisturization, as they are allowed to soak into the skin.

Topical steroids may be required if allergy is suspected. In most cases, hydrocortisone and corticosteroid creams are very effective.

Associated infections like scalp infections and fungal infections should also be treated with suitable products.

Immunomodulator creams like Elidel are useful by suppressing the immune system and preventing flare up of the allergic reactions.

Cold compresses may be used to relieve itching.

Prevention

Since there is a strong genetic component related to eczema, prevention is helpful.

Constantly keep the skin moist and hydrated by using moisturizers, especially during winters.

Avoid clothes and metals which can cause allergy- like wool, nickel, harsh soaps, detergents, etc.

Avoid or be careful about food items which are known to cause allergies.

Eczema - Causes, Symptoms and Treatments 

Atopic Dermatitis is a specific type of eczema which occurs when the epidermal layer of the skin is affected by eczema causing bacteria and other microorganisms. These eczemas are treatable and homeopathy finds a simple and natural solution to this disease. It not only helps to contain the disease from spreading it to other parts of the body but also helps in curing it of the root itself. There are some quick and effective remedies towards atopic dermatitis through homeopathy. Some of these are explained below.

Antimonium Crudum: People who have eczema which manifests as thick and hard boils are often given this medicine. In fact, it is administered both to children and the elder people. It has been seen that those who show symptoms of irritability in their behavior, get angry very soon and are most likely to be left alone, are the ones who are given this treatment to cure their eczema.
Arsenicum: Sometimes eczema is formed where boils turn thick and hard and have pus oozing out of it. For such skin infections, Arsenicum is the most widely used medicine that the homeopathic practitioners rely on. People who face such kinds of skin diseases are often seen to be depressed or melancholic in their lives. Thus, their mental feelings are often manifested in the form of eczema on their body.
Calcarea Carb: Eczema not only occurs on the body but also on the scalp. There are a few kinds of infections which have their roots on the scalp and then it starts spreading all over the face. For such kinds of infection, Calcarea Carb is the best form of homeopathic medicine which can be administered. In fact, patients with this problem are mostly children.
Graphites: Seems to be a very powerful and effective medicine against eczema which resembles ars. It is given to those patients whose skin becomes very hard and rough and there seems to be pus formation within the infection. Eruptions may be occurring in the eyes, behind the ears, and on the cheeks. Such infections are treatable with graphites.
Thus, if you are showing signs and symptoms of atopic dermatitis, then you should immediately consult your nearest homeopathic practitioner and get the proper medicine prescribed for yourself. Eczema would only spread and cause irritation in the skin if not timely treated and homeopathy offers one of the best types of treatments for this purpose.

Homeopathic Treatment For Atopic Dermatitis!

Sitting or standing slouched does not only look bad but also has a bad effect on your spine. If not addressed in time, bad posture can become a person s second nature. Over time bad posture can change the natural curvature of your spine and lead to a number of health issues. Here are a few tips that could help:

1. Follow the structure of the chair
We spend a lot of time on office chairs. A well-designed chair will follow ergonomic guidelines to support your body. However, this can help only if you sit on the chair properly. Distribute your weight evenly on the chair. Try to align your body to the center of the chair. To do this try keeping your ears, shoulder, and hips in a straight line. Alternate between sitting at the edge of your seat and against the backrest to relieve your back muscles.

2. Change Positions
Though you can t change your desk every few hours, you can change how you sit. Tiredness is one of the leading causes for slumping and bad posture. Thus, to maintain a good posture try changing positions frequently. Stretch every half hour or so. Getting up from your table and walking over to a colleague to tell them something instead of calling them can give your muscles a break.

3. Use posture-friendly props
Along with ergonomic chairs, there are a number of other ergonomic props that could help maintain good posture. This includes footrests, pillows to support the lower back and lumbar back supports. These props can help ease the strain on the back muscles. Using a chair with an adjustable back is also a good idea. While walking, invest in bags and backpacks that are ergonomically designed to distribute their weight evenly over the entire back.

4. Exercise right
Improved posture is one of the many benefits of regular exercise. Cardiovascular exercises such as walking, running, and swimming help condition the body and maintain a good balance. Exercises that strengthen the back muscles are also great for posture. These exercises support the muscles of the upper body and relieve stress on the back muscles.

5. Wear the right footwear
Wear shoes that fit right and support the arches of your foot. This can help you maintain your balance and improve posture. Avoid wearing high heels for extended periods of time as they could have a negative effect on your center of gravity. In case you have a concern or query you can always consult an expert & get answers to your questions!

Tips For Improving Posture And Ergonomics!

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