Glomerulonephritis is a disease that is caused due to inflammation of the small filters that are present within the kidneys or glomeruli. Glomeruli eliminate the excess waste, electrolytes and fluids from the blood, discharged through urine. A glomerular disease can be either acute or chronic. If the condition arises without a combination of any other disease, it is termed as primary glomerulonephritis. Secondary glomerulonephritis is characterized by diabetes or lupus (an auto-immune disorder) being at the root of the disease. Prolonged or severe inflammation can take a toll on the kidneys.


Causes-


Nephrotic syndrome can be primary, being a disease specific to the kidneys, or it can be secondary, being a renal manifestation of a systemic general illness. In all cases, injury to glomeruli is an essential feature. Kidney diseases that affect tubules and interstitium, such as interstitial nephritis, will not cause nephrotic syndrome.


Primary causes of nephrotic syndrome include the following, in approximate order of frequency:
Minimal -change nephropathy
Focal glomerulosclerosis
Membranous nephropathy
Hereditary nephropathies


Secondary causes include the following, again in order of approximate frequency:
Diabetes mellitus
Lupus erythematosus
Viral infections (e.g., hepatitis B, hepatitis C, human immunodeficiency virus [HIV] )
Amyloidosis and paraproteinemias
Preeclampsia
Allo-antibodies from enzyme replacement therapy


Nephrotic- range proteinuria may occur in other kidney diseases, such as IgA nephropathy. In that common glomerular disease, one third of patients may have nephrotic- range proteinuria.


Nephrotic syndrome may occur in persons with sickle cell disease and evolve to renal failure. From a therapeutic perspective, nephrotic syndrome may be classified as steroid sensitive, steroid resistant, steroid dependent, or frequently relapsing.


Treatment-
Whether one is suffering from acute or chronic nephrotic glomerular , with symptoms moderate or severe, the treatment lies in treating high blood pressure and other underlying conditions of the disease.
Water pills help control sweating, thus increasing the fluid flushed from the kidneys.
Statins reduce cholesterol level.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
For kidney failure, dialysis can come to the aid in eliminating excess fluids and regulating hypertension.


Nephrotic Syndrome: Causes and Treatment

At the point when our bodies process the protein we eat, the procedure creates waste products. In the kidneys, millions of tiny blood vessels act as filters since they have even tinier holes in them. As blood flows through these vessels, little molecules such as waste items may press through the gaps. These waste items turn out to be a part of the urine. Helpful substances such as protein and red blood cells are too enormous to go through the gaps in the filter and stay in the blood.

Diabetes and kidneys: Diabetes can harm the kidneys. Abnormal amount of glucose make the kidneys filter a lot of blood. After a couple of years, they begin to spill and helpful protein is thereby lost in urine. Having low protein levels in the urine is called micro albuminuria.

Medication: When kidney disease is analyzed on time, during micro albuminuria, a few medications may keep kidney disease from getting worse. Having elevated levels of protein in the urine is called macro albuminuria. When kidney disease is looked up some other time during macro albuminuria, end-stage renal disease (ESRD) usually follows.

Causes: Strain on the organs may cause the kidneys to lose their filtering capacity. Waste items then begin to develop in the blood. Finally, the kidneys start to fail. This failure, ESRD, is intense. A patient with ESRD needs a kidney transplant or a blood filtration by a machine (dialysis).

Other complications: Individuals with diabetes will probably have other kidney-related issues such as bladder infections and nerve damages in the bladder.

Preventing complications: Not everybody with diabetes goes through a kidney disease. Elements that can impact kidney disease improvement include genetics, blood sugar control and blood pressure. The more a person keeps diabetes and blood pressure under control, the lower the chances of getting a kidney disease.

Keeping your glucose levels high can counteract diabetic kidney problems. Research has demonstrated that blood glucose control diminishes the danger of micro albuminuria by 33%. For individuals who suffer from micro albuminuria have now a reduced danger of advancing to macro albuminuria. Different studies have recommended that blood glucose control can reverse micro albuminuria.

Treatment: Essential treatments for kidney infection include control of blood glucose and blood pressure. Blood pressure dramatically affects the rate at which the condition progresses. Indeed, even a gentle increase in blood pressure can rapidly aggravate a kidney infection. Four approaches to bring down your blood pressure are:

Shedding pounds
Eating less salt
Maintaining a strategic distance from liquor and tobacco
Exercising regularly
A low-protein diet can decrease the amount of lost protein in the urine and increase the protein levels in the blood. Never begin a low-protein diet without talking to your physician.

Diabetes - How It Impacts Your Kidney?

Kidney failure and other kidney problems are the leading causes of death nowadays. Common problems that lead to kidney failure include chronic blood pressure and chronic uncontrolled diabetes. However, there are a number of ayurvedic medications which help solve kidney failure and other kidney problems including;

1. Punarnava

Punarnava is commonly called hogweed as well but the medical name for it is boerhavia diffusa. It is extremely helpful in preventing micturition, a disorder which is characterized by unexplained fainting after urinating. However, that is not the only symptoms hogweed helps with as it also removes excess water from the body due to kidney failure.

2. Varun

Varun is commonly known as caper and is medically known as crataeva nurvala. The diseases which varun is best at dealing with are urinary tract infections and renal stones. Varun also helps in stopping the swelling and extra fluid accumulation after kidney failure.

3. Gokshura

Gokshura is known as tribulus terrestris and is an herbal tonic for the genito-urinary system. Gokshura is one of the best ways to avoid dialysis. This is because it stops infections from occurring and also clears obstructions in the urinary tract. It is also very good at regenerating the kidney cells.

4. Raktachandan

Rakt chandan is known as p. Santalinus or red sandalwood and is another excellent remedy for kidney problems. It acts as both a diuretic and an anti-infectant.

5. Palaash

Palaash, medically, is known as butea monosperma. It is a type of urinary alkalizer and it also stops micturition. A urinary alkalizer is a medication which allows the urine to pass more easily. This is yet another great remedy for kidney failure.

6. Kaasni

Kaasni is commonly known as chicory but its medical name is cichorium intybus. Kaasni gives strength to the kidneys and is also a very good alkalizer. However, its most valuable property is the fact that it helps in nephritis and nephrotic syndrome (disorder of the kidneys characterized by protein loss).

Ayurveda and Kidney Problems

Kidneys work aggressively day and night - this pair is responsible for all the cleaning - Waste Removal from your body.

Check out how you can keep your pair of kidneys functional right until you need them:

1) Increase Fluid Intake: No.1 reason for kidney stones/problems is not drinking enough water. When your fluid intake is low, it puts extra work load on the kidneys to pass toxins. Similarly excessive alcohol intake leads to dehydration and puts pressure on your kidneys making them age earlier.

2) Cut Back On Salt: Salt is anti-kidneys. If you have any chronic problem, try to aim for less than 2,300 milligrams of sodium each day.

3) Empty Your Bladder: Do not keep urine stored in bladder for too long. It majorly affects the functioning of kidneys.

4) Check On Chronic Problems: Manage your diabetes, high blood pressure, and heart disease well. These have direct impact on Kidneys, esp. Your cholesterol levels, sugar levels and blood pressure. Having high cholesterol, especially if you have diabetes, puts you more at risk for kidney disease, heart disease and stroke.

5) Balance your Physical Health: Keep your body active to keep organs such as kidneys in good functioning. Do at least 15 min of cardio exercises daily. Also, get sufficient rest for your body.

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5 Ways to Keep Your Kidneys Active

The pair of kidneys that human beings have, forms an important part in the excretory system. They perform specific and important functions. They excrete urine as well as help in eliminating the toxins, which accumulate in the body. Kidney stones occur when the minerals present in the urine without being discharged, keep on accumulating. This gives rise to an extremely painful and uncomfortable situation. Though sometimes the situation gets revoked all by itself, many a times it requires medical intervention. 

Some of the symptoms of kidney stones are: 
1.  Excruciating pain in the back
2.  Pain while urinating
3.  Tendencies to vomit
4.  Dizziness
5.  Fever 

However, there are several preventive measures which you can undertake in order to avert the situation. Some of them are:
1.  Drink lots of water
Kidney stone is one of those rare conditions that once occurred, always carry the latent threat of recurring again. Therefore, drinking water in large quantities becomes essential. The more you drink water, the more frequently you would urinate, thereby curbing the chances of the minerals settling in the kidneys.
2.  Avoid certain foods
Food like beets, spinach, those which are replete with calcium oxalate should be avoided in order to minimize chances of having kidney stones.
3.  Change your diet
If you are trying to avoid the eventuality of developing kidney stones, it is imperative that you change your diet a bit. It is recommended that you exclude animal protein as much as possible and assiduously avoid the intake of salt as much as possible.
4.  Take less calcium supplements
Calcium generally is considered a nemesis to your kidneys and is prescribed by doctors to be avoided. However recent research has thwarted this claim. Calcium does not pose a threat to kidneys. However calcium supplements definitely do and therefore, should be avoided.

All About Kidney Stones

Problems of the large intestine are very common and patients should usually consult gastroenterologists for the proper diagnosis and treatment

1. Bleeding per rectum: Bleeding through the anal canal or rectum is usually the most common problem of the patients. It can be due to following reasons: 

A. Piles also known as Hemorrhoids: Hemorrhoids are dilated venous channels of the anal canal. They occur due to long term constipation or chronic cough or due to less fibre intake in the diet. Sigmoidoscopy or proctoscopy is required for diagnosis. Treatment options include medicines and high fibre intake, Injection therapy(Sclerotherapy) for stopping bleeding from piles and Stapler hemorrhoidectomy if the piles are large.

B.  Polyps: Polyps are soft tissue growths seen in the large intestine. They are usually silent but can present with bleeding or anaemia. Polyps usually grow slowly in size and large polyps can turn into cancer of large intestine also known as colorectal carcinoma. Colonoscopy is required for the diagnosis. The gastroenterologists can diagnose the presence of polyps by colonoscopy. Smaller polyps can be removed by polypectomy by gastroenterologists without the need for open surgery. However large polyps or those polyps with suspicion of cancer require surgery.

C. Large intestine Ulcer: They can occur due to early cancer, SRUS, Infections or drugs. They require colonoscopy for the diagnosis. The gastroenterologists usually take Biopsy from the ulcer to know the cause of the ulcer. The mere taking of biopsy does not mean cancer and biopsy samples are seen in the microscope for better diagnosis.

D. Ulcerative Colitis and Crohn s disease: Ulcerative colitis is one form of Inflammatory bowel disease (IBD). The other IBD is known as Crohn s disease. Whereas ulcerative colitis involves only large intestine, Crohn s disease can involve any part of the gastrointestinal tract including small intestine. Ulcerative colitis and Crohn s disease present with Loose stools(diarrhea), bleeding , abdominal pain, weight loss, Anemia and Perianal fissures and  fistula. The diagnosis of IBD is challenging and involves blood tests, CT Scan abdomen, Colonoscopy with biopsy and clinical history. Management includes Medicines which control the inflammation such as Pentasa, Rowasa, Mesacol etc. Severe disease requires additional drugs such as Azathioprine and Anti TNF sich as Infliximab and Adalimumab. Occasional cases require surgery such as those with tight stricture of the intestine, severe dilatation of Large intestine (also known as Toxic megacolon), excessive bleeding, the disease not responding to medical management, or presence of cancer with IBD.

E. Anal fissures: Cut in the anal skin (fissure) causes severe pain in the anal area during passing motions. It is usually due to constipation or straining. It is usually treated by Gastroenterologists initially by medicines and ointments. If the pain continues Surgery is required named as Lateral internal sphincterotomy (LIS).

2. Loose motions or Diarrhea: Excessive passing of liquid motions is known as diarrhea or commonly lose motions. It is usually due to Infections caused by contaminated food and water. It is usually self-limiting. Severe cases with dehydration require admission for IV fluids and antibiotics for the infection. Loose motions for more than 6 to 8 weeks is known as chronic diarrhea. It is evaluated by blood tests and colonoscopy. Usual causes include tuberculosis, celiac disease, ulcerative colitis, microscopic colitis, Malabsorption such as chronic pancreatitis and small bowel bacterial overgrowth.

3. Irritable bowel syndrome (IBS): IBS is very common and at least 20 to 30 percent of Indian patients suffer from it. Symptoms include altered bowel habits such as diarrhoea or constipation, abdominal pain which is usually relieved or increased by defecation. Weight loss or bleeding is not the feature of IBS. Few simple blood tests are required and good medicines are now available for IBS. Few cases may require colonoscopy to rule out alternative causes of the symptoms.

Understanding colonoscopy: Colonoscope is a flexible tube with a camera at its tip to see the inside of the large and small intestine. Bowel preparation is required at least 8 hours before the procedure so that the inside of the large intestine can be seen clearly without the interference of stools.colonoscopy is an OPD based procedure where the patients are discharged the same day. A colonoscopy helps in evaluation symptoms of the large intestine such as loose stools, bleeding and abdominal pain.

In Detail About Colorectal Disorders!

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