It is true that most people are aware of the fact that  angina  is a term which has something or the other to do with the heart. That being said, very few would be able to answer a question regarding what exactly it is, in a satisfactory manner. So would it not make sense to know more about it and become one of the few?

The term is derived from the ancient language of Latin and refers to a tightness that is felt or a squeezing of the chest. This happens when there is not enough oxygen-rich blood which is reaching the area of the heart muscle. While many people think that angina is a disease, it is actually not true to think that it is! As a matter of fact, it is a symptom of coronary artery disease. It is this disease which is the most common disease which affects the heart.

But why exactly does a person experience angina? Well, the lack of blood which is rich in oxygen occurs when it so happens that the coronary arteries become narrower than they normally should be. This generally happens due to the build-up of plaque. The condition in which this happens is known as atherosclerosis.

When it comes to the sort of people who are at a higher risk of developing angina, it can be said that those who smoke tobacco really do increase their risk, as do those who are overweight or obese and have other lifestyle diseases such as diabetes.

In order to avoid angina, the most important thing a person can possibly control is his or her lifestyle. In fact, a lot of the risk factors related to angina are attributable to the lifestyle a person chooses to lead. Cholesterol levels can be controlled if a person puts enough attention and effort in. Also, avoiding a lifestyle that is sedentary by exercise can not only help with cutting the risk of angina but also the risks of other conditions such as high blood pressure. It is ironic that high blood pressure is one of the potential signals of angina!

It is to be noted that while most people just call angina as it is, there are various types-

Stable angina is when the heart is working harder than usual and medicine helps improve this.

Unstable angina occurs even at rest and is unpredictable. It may also be a signal of a coming heart attack.

Variant and microvascular angina is relievable by medicine and is generally rare.

What Is Angina?

Brain metastases from systemic cancer are the most common type of intracranial neoplasm in adults, being almost 10 times more common than primary malignant brain tumors, which cause a significant burden on the management of patients with advanced cancer (1). The lungs represent one of the most frequent sources of metastases to the brain, with a probability of (36 64%) (3). Symptoms suffered by the patients include headaches, epilepsy, focal weakness, numbness or changes in mental status. The prognosis of patients with brain metastases is not optimistic and the median survival time is  1 2 months if left untreated. The 1-year survival rate has been recorded as 10.4% (4,5). The treatment of metastatic brain tumors is complex; not only due to being able to provide local control and improve neurological function, but also due to factors such as age, performance and systemic disease status and the size, volume, location and number of metastases at presentation

CyberKnife is a robotic radiosurgery system with a linear particle accelerator (linac), which is coupled with real-time imaging to track and compensate for the patient s or target s motion. As a relatively non-invasive treatment modality, CyberKnife demonstrates certain benefits, including a more accurate target localization and improved dose delivery for the management of metastatic brain tumors that allows higher biologically effective dose delivery without increased incidence of toxicity.

In the present case, the results for the treatment of multiple brain metastases after CyberKnife surgery with a 7 8 Gy marginal dose was promising. CyberKnife for metastatic brain tumors is an effective and safe method for reducing the marginal dose prescribed for multiple brain metastases and for minimizing the radiation-related neurotoxicities. In conclusion, CyberKnife, a focused, highly-targeted radiosurgery and fractionated radiotherapy is particularly useful for multiple brain metastases. CyberKnife provides the advantage of the management of local recurrence and a tolerable complication rate. Although the treatment of brain metastases has been performed with CyberKnife, the clinical significance and optimal dose fractionation scheme require further investigation.

In case you have a concern or query you can always consult an expert & get answers to your questions!

CyberKnife Therapy Of 24 Multiple Brain Metastases From Lung Cancer!

Cancer like most other diseases has the best rates of recovery with early detection and intervention. As there are no regular health screenings for blood cancer, only the awareness about the early warning signs can save your life. November is designated as the Lung Cancer Awareness Month, to ensure every individual is equipped to fight against lung cancer right from the start. Here are 4 vital facts you must know to win your fight against blood cancer.
Lung cancer is also known as pulmonary carcinoma or cancer of the lung. It occurs when DNA mutations develop in the cells/ tissues of the lungs leading up to uncontrolled growth in the tissues of the lung. By far, it is known to be the most common cancer in Asia.

1. Type: lung cancers can present as one of the following types: 

Non-Small Cell Lung Cancer (NSCLC): Most common type of lung cancer and constitutes nearly 85% of all lung cancers. The sub-types of NSCLC are as follows:
Large cell carcinoma
Squamous cell carcinoma (SqCC) (Epidermoid)
Adenocarcinoma   accounts for majority of the NSCLC.
Small Cell Lung Cancer (SCLC): It is also known as oat meal cancer and tends to spread (metastasize) quickly. This constitutes about 15% of the lung cancers.
Mesothelioma: It is a rare cancer that develops in the mesothelial cells of the pleural or peritoneal surfaces. It usually arises in the pleural membrane lining the lungs, known as pleural mesothelioma. One that arises from the peritoneum is called the peritoneal mesothelioma and the one that arises from the pericardium is known as pericardial mesothelioma. Lastly, it can also arise from the tunica vaginalis known as testicular mesothelioma. People working with or prior exposure to asbestos are mostly at risk of developing mesothelioma. The latency period between time of exposure and development of mesothelioma can be somewhere between 20 to 40 years. Maximum of the patients who develop mesothelioma are men.
2. Gender: It affects the male populace predominantly. It is more common in men than in women and in those of lower economic status. However, the incidence of lung cancer, in women too, is on the rise of late.

3. Etiology: Cigarette/ Tobacco smoking remains the most important cause of lung cancer accounting for 85   90% of the cases. Incidence/ risk is proportionate to the number of cigarettes smoked irrespective of the age. Also, environmental toxins including smoke from burning black tar, exhaust gases from automobiles etc. too contribute actively to various lung diseases including cancer. People working in asbestos manufacturing factories who are exposed to asbestos dust are also likely to get lung cancer. Tuberculosis too is an additive risk factor. Again, people who have received ionizing radiation especially to treat Hodgkin Lymphoma or other malignancies also run the risk of developing lung cancer. Above-mentioned causes apart, genetic factors may also play a role.

4. Features: Lung cancer clinically presents in the following ways mainly. Signs & symptoms of malignant mesothelioma are as enumerated below

Difficult/ labored breathing (Dyspnea)
Chest pain
Palpable chest wall mass
Discordant chest wall expansion
Weight loss (Cachexia)
Loss of appetite (Anorexia)
Night sweats
Signs & symptoms of non-small cell lung cancer (NSCLC) are as enumerated below. Majority of patients are symptomatic at diagnosis

Chronic cough
Difficult/ labored breathing (Dyspnea)
Chest pain
Blood stained sputum (Hemoptysis)
Hoarseness
Weight loss (Cachexia)
Loss of appetite (Anorexia)
Weakness
Bone pain
Pleural or pericardial effusion
Superior vena cava syndrome
Brachial plexopathy
Neurologic pain
Hypercalcemia of malignancy
Signs & symptoms of small cell lung cancer (SCLC) are as enumerated below

Symptoms as per the points 8   18 depicted above for NSCLC are applicable for SCLC as well. Additionally, patients suffering from SCLC may have:

Fever associated with chest infections like bronchitis/ pneumonia that refuse to go away or keep coming back
Horner syndrome
Paraneoplastic syndromes including encephalitis/ sub-acute sensory neuropathy, hyponatremia, acromegaly, cancer associated retinopathy, ectopic corticotropic syndrome etc all.
5. Screening: is generally recommended for asymptomatic/ symptomatic populations as surveillance for high-risk individuals   who are either current or former smokers (quit smoking within the last 15 years) have at least a 30 pack-year smoking history and those who do not have any prior history of lung cancer. The goal of screening, as usual, is to be able to detect & diagnose lung cancer at an early stage which is potentially curable. It is mostly radiologic with a low dose helical computed tomography (CT) scan being more effective in detecting early-stage lung cancer than a chest radiograph can.

6. Diagnosis: Abnormal blood test results may be indicative of malignancy, but a follow-up imaging/ biopsy is always the gold standard for an accurate diagnosis. Following are the diagnostics employed mainly:

Blood: Hb may be low, TLC, ESR and polymorphs increased. Adenocarcinomas are likely to express thyroid transcription factor 1 (TTF-1) or carcinoembryonic antigen (CEA). On the other hand, mesotheliomas are likely to express Wilms Tumor -1 (WT-1) protein and Calretinin.
Imaging: Thoracoscopy, Bronchoscopy, X-Ray, CT Scan etc all. Positron Emission Tomography (PET) / CT scan and Magnetic Resonance Imaging (MRI) scan help detect metastasis if any.
Biopsy: It clinches the histologic diagnosis and the nature of the disease.
7. Treatment: Conventional treatment includes surgery, chemotherapy and radiotherapy as contextually appropriate. Simultaneously, an adjunctive or integrative naturopathic treatment with suitable complementary & alternative medicines (CAM) too can help improve clinical outcomes and facilitate recovery as would be feasible contextually.

8. Prognosis: Preventive measures, earlier diagnosis and right early treatment are key for effective therapeutic management & better prognosis. Like most other cancers, the chances of cure for early-stage lung cancer are more. The cure/ recovery chances are influenced by the grade, stage of cancer, recurrence and the patient s general health & vitality etc all. The primary determinant of prognosis in NSCLC is the stage at which the cancer is diagnosed. For non-metastatic cancers, however, it is the nodal status that determines the stage and hence the prognosis.

9. Prevention: Rightly said, prevention is always a better choice. Cigarette smoking is to be avoided by all means as it is the single major cause of lung cancer. Even exposure to cigarette smoke (passive or secondhand) is also an established cause of lung cancer and is known to increase the risk of lung cancer in non-smokers as well. Preventing exposure to secondhand smoke can be helpful in decreasing the incidence and mortality of primary lung cancers. Above-mentioned apart, other important risk factors such as exposure to ionizing radiation, environmental carcinogens like smoke from burning black tar, exhaust gases from automobiles, outdoor air pollution, and occupational exposure to asbestos, arsenic, beryllium, nickel, cadmium, chromium etc all too are known to increase the risk for lung cancer and mortality thereof. In fact, cigarette smoking is known to potentiate the effect and hence the lung cancer risk of many of the above-mentioned carcinogens, multi-fold, in smokers. Thus, either eliminating or reducing the exposure to the above-mentioned carcinogens can lead to a decrease in the risk of lung cancer and incidences thereof. Furthermore, randomized clinical trials indicate that high-intensity smokers (only) who take supplementation of beta-carotene have an increased risk/ incidence of lung cancer. Vitamin E supplementation, on the other hand, does not affect the risk of lung cancer as indicated by the trials. 

In case you have a concern or query you can always consult an expert & get answers to your questions!

Lung Cancer Awareness Month - Lung Cancer In Nutshell!

Tuberculosis is a highly infectious and potentially fatal disease which primarily affects the lungs. It is highly contagious and can infect other people via the tiny water droplets released by an infected person while coughing or sneezing. Some strains of this disease have the potential to resist drugs, which are commonly used to cure tuberculosis.

Read more to find all about the different causes, symptoms, preventive measures and the treatment of tuberculosis:

Symptoms: Tuberculosis, also known as TB, can be both latent and active. In latent condition TB is not contagious and it does not harm the infected person. But latent TB can change to an active form so treating it in its latent condition is highly advisable. Active TB can be diagnosed due to the prevalence of certain symptoms such as a cough, which lasts for more than 3 weeks, coughing up of blood, unintentional weight loss, chills, chest pain, loss of appetite and fever. Tuberculosis mainly affects the lungs, but can also affect your kidneys, brain and spinal cord.
Causes: Tuberculosis in general is caused by infection. It spreads from person to person by ultra-small droplets, which an infected person releases while coughing or sneezing. Tuberculosis is highly contagious but it is not very easy to catch TB as the immune system of your body fights it off. Also if a patient of TB is under treatment, the person 's disease is no more contagious.
Risk factors: Potentially everyone can be infected with TB but certain factors increase the chances of infection such as a weakened immune system, living in or travelling to certain areas and substance abuse. TB can also cause complications such as spinal and joint damage, liver or kidney problems and heart disorders.
Treatment: Administering medical drugs is the most convenient way of treating TB. But TB is more persistent than normal bacterial infections and utmost care and caution must be taken to treat it. Completion of treatment is highly essential to fully cure TB. Some of the side effects of TB medication include loss of appetite, nausea or vomiting, dark urine and jaundice.

World Tuberculosis Day - Know More About It!

Ways To Prevent Tuberculosis

Tuberculosis happened to be a life threatening disease till some years ago. Now, it is curable with medication, however there is very little awareness about the same. It is crucial that awareness is spread to put a stop to this disease. TB spreads through infection, so a simple sneeze or a cough can also be hazardous. Here is how you can stop the spreading:

1. Curb the Spread - If someone already has tuberculosis, they need to cover their mouths when coughing or sneezing. This is actually a habit everyone should follow, as there are many people in whom the tuberculosis virus exists but is dormant.
2. Don’t let it activate - If you have latent tuberculosis, where you have none of the symptoms yet have been identified, you need to take the medication prescribed so that it doesn’t become active.
3. Complete the course - TB is curable but only when medications are taken regularly, strictly, and as prescribed.
4. Avoid exposure to the infected people - People who have been exposed to TB patients should get themselves tested. Remember it spreads through infection; patients need not be kept in isolation if taking proper care and medication.
5. Boost your immunity - Ensure that your own immunity is strong. People with low immunity are at extreme risk of contracting tuberculosis. Take special care if you are a caretaker of someone being treated for tuberculosis, if you do drug and/or alcohol abuse, if you live in crowded spaces like shelters, etc.
6. Improve your lifestyle - Lead a healthy lifestyle by eating healthy, exercising often, reducing alcohol consumption, sleeping well and maintaining good hygiene.


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How To Prevent Tuberculosis(TB) From Spreading And Safeguard Yourself

Tonsillitis is an affliction that plagues a fair share of people. Located at the back of your throat, tonsils are essentially two small glands, which contain white blood cells to defend your body against infection. However, on account of germ attacks, sometimes the tonsils get infected and this results in the swelling of the tonsil glands, which in turn causes sore throat and aligned maladies. 

Tonsillitis may be cured through surgical procedures. However, an isolated case of the inflammation of the tonsils need not warrant a surgery. Tonsillectomy or the surgical method of curing tonsillitis is only recommended for extreme cases of tonsillitis. Only the frequent sufferers of tonsillitis take recourse to tonsillectomy for a durable and effective solution. Surgeries are only done on those who have had at least seven bouts of strep throats within a span of a year. 

Tonsillectomies essentially involve surgical removal of the tonsils either using a scalpel or burning the tissues in the tonsils with the use of ultrasound vibrations. Usually performed under anesthesia, it is a fairly painless and a non-hazardous procedure. Tonsillectomies generally last for about an hour. However, the recovery period sometimes entail a few physical discomforts. Sore throat, difficulty in swallowing, pain in the jaws and ears are common symptoms of post tonsillectomy conditions. While there are palliative medicines available in the markets, adequate rest and proper diet speeds up the recovery. 

Tonsillectomy generally leaves no side effects and the success rate of this surgery is quite heartening. Tonsillectomy has also known to cure several other associated health problems in the likes of breathing troubles, sleep apnea, bleeding of the tonsil glands or cancerous developments in the tonsil glands. That aside, tonsillectomy is only performed on acute cases of tonsillitis and often regarded as the lender of last resort when medicines stop according any relief to the patient.

When to go for a Tonsil Surgery?

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