What are the different types of sickle cell disease?

Sickle cell disease or sickle cell disorder is a term often used to talk about a group of diseases affecting hemoglobin. It is the oxygen-carrying element of blood that makes up 2 alpha globins and 2 beta globins. Sickle cell disease happens due to beta-globin mutation and depending on the abnormality in mutation.

Types-
Sickle cell diseases can be of many types depending on the gene mutation in the blood. Some of the common types are-

Sickle hemoglobin s disease (ss)
Hemoglobin ss disease or sickle cell anemia is the most popular type of scd. It takes place when hemoglobin s gene mutation is inherited from both mother and father. In simple words, it happens when the child inherits one substitution beta-globin gene from each parent. In this type, the body only produces hemoglobin s. It is mostly found in people of african and indian origin.

Sickle hemoglobin- c disease (sc):
Patients with sickle hemoglobin sc disease have a moderately dissimilar swapping in their genes of beta-globin. Here, both hemoglobin c and hemoglobin s are inherited from each parent. It may cause similar symptoms like anemia but remains relatively l. People of west african and mediterranean origin are more prone to this.

Hbs beta-thalassemia
People with this type of scd inherit one sickle cell gene s and one gene for beta-thalassemia from each parent. Zero and plus are the two common types of beta-thalassemia. While beta 0 thalassemia usually takes a severe form, beta + thalassemia is a milder form of the disease.

Sickle beta-zero thalassemia
Beta-zero thalassemia takes form when the child inherits the beta s gene from one parent and beta 0 thalassemia gene mutation from the other. With similar symptoms to anemia, it is a slightly severe form of beta-thalassemia.

Sickle beta-plus thalassemia
Substitutions in both beta-globin genes take place in patients with sickle beta thalassemia (sb) disease. This may even lead to the requirement of blood transfusion if no normal beta globin is produced. Mediterranean and caribbean people are more likely to have this disorder.

Hemoglobin sd, hemoglobin se, and hemoglobin so
These are the few rare and not less common types of sickle cell diseases. They are also less severe. People with these forms of scd inherit one sickle cell gene s and one gene from uncommon hemoglobin (d, e, or o) from each parent.

Sickle cell trait
Hbas
People with sct have one sickle cell gene s and one normal gene a from both mother and father. Ones with this disorder show few to no signs of the disease and usually spend a normal life. However, the risk to their future generations still exists.
 

What Are The Different Types Of Sickle Cell Disease?

Atherosclerosis refers to a medical condition in which the arteries become hardened and narrowed due to the accumulation of cholesterol plaque in the walls of the artery, obstructing the flow of blood.

What are the causes?

Atherosclerosis is a slow but progressive disorder that starts with the damage of endothelium   cells lining the interior surface of lymphatic and blood vessels. This allows bad ldl cholesterol to build up in the artery walls. Over time, a plaque made of calcium, macrophages, and cholesterol grows to a certain size to clog up arteries, disrupting blood flow around the body.

Other factors leading to atherosclerosis to include  

High blood pressure

High levels of triglyceride in the blood

High cholesterol levels

Certain medical conditions   diabetes, obesity, insulin resistance

Smoking/use of tobacco

Inflammatory conditions like lupus and arthritis

Symptoms of atherosclerosis

Atherosclerosis may develop in childhood or during adolescence. Mild conditions may not reveal observable symptoms unless the arteries are clogged, and blood supply to the tissues and organs are restricted.

Signs of moderate to severe atherosclerosis depend on the affected arteries   it could be the arteries leading to your brain, your heart, legs and arms, or the kidney. The symptoms of atherosclerosis include  

Weakness and fatigue

Difficulty breathing/concentrating

Headaches

Facial numbness

Paralysis

Vomiting

Chest pain

Anxiety

Loss of appetite

Swelling in the feet and hands

If any of the above symptoms seem familiar to you, consult a doctor right away for treatment.

Can atherosclerosis be prevented?

The best way to avoid cholesterol plaque from building up in the artery walls is to prevent the onset of atherosclerosis with these preventive measures.

Eat healthy   avoid eating foods that are rich in saturated fats   red meat, butter and cheese. These increase your cholesterol levels drastically. Instead, include foods that contain unsaturated fats, like avocados, olive oil, fatty fish, nuts and seeds because these help to keep ldl or bad cholesterol levels down.

Stay active   exercising and staying active can help regulate your cholesterol levels and prevent certain conditions that might put you at risk for atherosclerosis.

Quit smoking   people who smoke should quit smoking because it is a major risk factor for atherosclerosis   it increases blood pressure, which in turn, affects your cholesterol levels.

Atherosclerosis can lead to complications. With precautionary measures and proper treatment, the condition can be avoided.

Know All About Atherosclerosis Here

The world celebrates world blood donor day on the 14th of june to raise awareness of the need for safe blood and blood products and to thank voluntary and unpaid blood donors for their life-saving gift of blood. 

Importance of blood donation

The importance of donating blood is not only to save the lives of thousands of people who are deprived of life but also to save the lives of many more who are affected by the various diseases. ;

 

It has also been seen that when people; e have donated their blood, they have gained many health benefits as it helps in weight loss, helps maintain healthy liver and iron levels, it helps reduce the risk of heart attack and cancer. ;

 

A blood donation can save a life of- ;


	
	Victims of natural disasters, including earthquakes
	
	
	Patients with hemophilia, sickle cell disease, or cancer
	
	
	People who suffer traumatic injuries from being in a car accident
	
	
	Surgery patients
	
	
	Shooting or stabbing victims
	
	
	Women who suffer complications during childbirth
	


 

Blood types that are needed most

It s good to donate if you re healthy. However, there s always a need for specific blood and plasma which are universal and can be used when a patient blood type is unknown. For newborn infants or if a patient's particular blood type is unavailable.

 ;


	
	Type o negative blood is always needed because it can be used in patients regardless of their blood type.
	
	
	Type ab positive plasma can also be transfused to patients with other blood types. 
	


 ;

Donations are constantly needed

Because of their short shelf life of 5 days after being collected, platelet donations are constantly by the blood blank. Red blood cells also have a short shelf life and needed to be used within 42 days after the collection. Cryoprecipitate and plasma can be frozen and stored for up to a year after donation.


 

Some misconceptions about blood donations


	
	The donor will not experience any kind of pain while donating. ;
	
	
	There will be no scarcity of blood in the body after donating the blood as even after the donation the body will have a surplus quantity of blood. 
	
	
	The common misconception everyone has is that they will faint after donating their blood. ;
	
	
	You will be able to resume your everyday activity immediately after donating the blood. 
	
	
	You will not get infected with aids if you donate your blood. ;
	


 

Donating blood is a great way to give back to your community and potentially save a life by only giving up an hour of your time.

World Blood Donor Day: How Can We Save Life By Donating Blood?

Yoga can cure numerous common ailments like asthma and arthritis if practised frequently. Yoga cannot cure diabetes, yet it is helpful in controlling the glucose in the body to a great level. There are different yoga asanas that are cures for lower back pain and acid reflux. Here is how yoga cures some common ailments:

 

Asthma: the main practical cure for asthma lies in yoga. Inhalers can spare your life when you get an asthma attack; however, for a long-term cure, you need to rehearse pranayam and anulom-vulom.

Diabetes: it is one of the most common illnesses on the planet. You cannot generally cure insulin resistance; however, some yoga asanas like the triangle posture (trikonasana) can control your glucose levels.

Heart disease: bhujangasana or cobra pose stretches the chest, massaging organs inside, including heart, and allowing more blood flow to it, thus stimulating and strengthening the heart muscle. Kapalbhati pranayama is also very good for the heart since it increases the absorption of oxygen in the blood. Yoga is proven to be an excellent heart risk improvement practice according to current research too.

Thyroid disorders: yoga asanas like shoulder stand, inverted pose, plough pose, and the fish pose all help in making the thyroid gland work optimally again. The cobra pose and ujjayi pranayama also work wonders by re-balancing metabolism and working on the throat reflex pathways to cure thyroid imbalance. ;

Headache: migraine and headaches are frequently brought on by insufficient blood supply to the brain. Attempt the yoga postures like shirsasana or a headstand to cure headaches or migraines as opposed to taking medicines.

Back pain or lower back pain: it has turned into a common condition among the working class and individuals even undergo surgery to stop the pain. Attempt yoga postures like tadasana or the tree posture.

Joint inflammation or arthritis: arthritis is an ailment that causes serious joint pain. However, yoga can control the amount of pain brought on because of joint inflammation. Attempt the surya namaskar as a flexible approach to cure arthritis.

Liver problems: liver issues can go from minor ingestion to extreme greasy liver disorder. To keep your liver sound, try some extremely basic yoga postures that may increase the blood circulation in the belly. The stretching posture is a great illustration.

Depression: yoga is one of the best and most powerful cures for depression. If you would prefer not to be reliant on antidepressants and dozing pills, attempt yoga asanas like uttanasana.

Polycystic ovaries syndrome (pcos): it is one of the most common problems that are troubling young women nowadays. The side effects are irregular periods, and it can even lead to infertility. So attempt yoga postures like the body stance to cure ovarian cysts without medications or surgery.

 

10 Diseases You Can Cure With Yoga

Hepatitis is a condition that affects the liver by causing inflammation which is a common outcome resulting from a viral infection. While different types of hepatitis diseases are caused by different causes, there are some reasons like medications, toxins, alcohol, and drugs that are typically known.

 

Types

The five common types of viral hepatitis are hepatitis a, b, c, d, and e.

 ;


	
	Hepatitis a
	


Hepatitis a is the result of an infection caused by the hepatitis a virus. This type of hepatitis is an acute disease.

 


	
	Hepatitis b
	


The hepatitis b virus causes hepatitis b. This is often a chronic disease that lasts longer.

 ;


	
	Hepatitis c
	


Hepatitis c comes from the hepatitis c virus. It is one of the most common bloodborne infections in the world. It is a long-lasting condition.

 


	
	Hepatitis d
	


This is a not so commonly found form of hepatitis that only occurs in hepatitis b infected people. This virus not only causes liver inflammation but also cannot be contracted without an existing hbv infection.

 ;


	
	Hepatitis e
	


Hepatitis e is waterborne. Hepatitis e virus infection is responsible for it. It is generally acute but can be severely chronic for pregnant women.


 

Causes of viral hepatitis

It is true that different types of viral hepatitis infections are caused by distinct modes of transmission. Here are the causes of a hepatitis infection:

 ;


	
	Hepatitis a- when a person is exposed to the hepatitis a virus through food or water.
	


 


	
	Hepatitis b- when an individual comes in contact with hepatitis b virus through the transmission of bodily fluids like blood, semen, etc.
	


 ;


	
	Hepatitis c- when someone gets infected with the hepatitis c virus through the contamination of bodily fluids.
	


 


	
	Hepatitis d- when a person is exposed to hepatitis d virus-infected blood, it causes this disease.
	


 ;


	
	Hepatitis e- when a person comes in contact with the hepatitis e virus through water or food.
	


 

Causes of non-viral hepatitis

Although hepatitis is commonly caused due to an infection, other factors can also be reasons to cause hepatitis.

 ;

Alcohol

Excessive alcohol can lead to liver damage, causing inflammation. It can also be called alcoholic hepatitis. The alcohol impacts the liver cells directly. Moreover, it can also cause cirrhosis or even permanent liver failure.

 

Autoimmune system response

In rare cases, the immune system of a person attacks the liver itself. It leads to inflammation that can be mild to severe according to the infection. Moreover, it s more common in females than in males.

How Is Hepatitis Caused And Some Common Types?

World hepatitis day is observed on july 28th every year to raise awareness about hepatitis disease among people. It is organized on the occasion of the birthday of Dr. Baruch blumberg who found the hepatitis b virus in the year 1967 and also developed a vaccine for it. Moreover, this day educates everyone about hepatitis infections, the efforts to fight viral hepatitis, and methods people can use for its prevention.

What is viral hepatitis?

Viral hepatitis or hepatitis disease is a condition of inflammation in the liver that leads to severe liver disease and hepatocellular cancer. With deaths happening every 30 secs from a hepatitis-related infection, it is important to treat viral hepatitis at the earliest. Hepatitis is of different types depending on the infection. 

 ;

Types

Viral hepatitis impacts millions worldwide, resulting in both acute and chronic diseases. There are five major classifications of viral hepatitis-

 


	
	Hepatitis a- it is a liver infection that can be prevented by a vaccine. It is a result of the infection as a result of the hepatitis a virus.
	
	
	Hepatitis b- it is an infection that happens due to the hepatitis b virus. It is spread through the blood or other bodily fluids of a person.
	
	
	Hepatitis c- it is a liver infection caused by the hepatitis c virus. It transmits through the blood of a person who is infected.
	
	
	Hepatitis d- delta hepatitis is another name for this virus and the hepatitis d virus is responsible for this. It happens to only those who are already hepatitis b infected. ;
	
	
	Hepatitis e- it is a liver infection resulting from a hepatitis e infection. It is usually found in a person s stool.
	


 

Symptoms

Hepatitis is a condition where you don t show symptoms till it is chronic and starts affecting your liver health. However, people in the initial stages of hepatitis infection might start reflecting symptoms. Some common symptoms of viral hepatitis are:

 ;


	
	Flu-like signs
	
	
	Darker urine color
	
	
	Fatigue
	
	
	Abdominal cramps and pain
	
	
	Appetite loss
	
	
	Weight loss
	
	
	Yellow skin
	
	
	Pale eyes
	


 

People at risk

The risk of catching a hepatitis infection is high in individuals working around these environments-

 ;


	
	Direct contact with hepatitis a infected person
	
	
	Male in sexual relation with another male
	
	
	Drugs abuser
	
	
	Ones with clotting factor disorder
	
	
	Who work with primates
	


 

World Hepatitis Day: Know All About The Disease

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