Cystic Fibrosis is a genetic disorder that is known to affect some of the vital organs of the body including the lungs, digestive system to name a few. For long it was believed that cystic fibrosis affects a person in their childhood. However, various research and studies suggest that adults are also susceptible to this inheritable disorder. In this article, we will discuss the cause and symptoms associated with cystic fibrosis.

Cause
The epithelial cells that line the stomach, nasal cavity and lungs, are responsible for the production of the digestive fluids, sweat, tears, mucus. The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene codes for a protein called the CFTR protein. The CFTR protein, a membrane protein plays a pivotal role in transporting the chloride ions of the epithelial cells inside and out of the cell. This regulation of the chloride ions goes a long way in ensuring that the mucus produced is free-flowing and thin.

In the case of Cystic Fibrosis, the CFTR gene that codes for the protein undergoes a mutation. With the CFTR protein unable to perform its function, sticky and thick mucus builds up and clogs some of the major systems of the body including the digestive system, reproductive, and respiratory system. There is also a higher salt content in the sweat of the affected person.

For a person to be affected by cystic fibrosis, he/she must inherit a copy of the mutated CFTR gene from both the parents ( Autosomal Recessive Disorder) at birth.

Symptoms
The symptoms associated with cystic fibrosis depends on the organs and systems affected.

The thick mucus formed can clog the digestive tract resulting in incomplete absorption of the essential nutrients from the food. This may have an impact on the overall growth and development of the body.
- There may be stunted growth or no weight gain.
- The stool may appear greasy and foul smelling. Some may also suffer from constipation.
- Newborns and infants may suffer from an intestinal blockage.
Cystic fibrosis, left unattended can lead to diabetes, intestinal blockage or obstruction.
- The mucus can also block the bile duct triggering a host of problems including liver disorders.
- At times, the obstruction or blockage can occur at the junction where the large and the small intestine meets (Distal intestinal obstruction syndrome).
The thick mucus can also affect the lungs and the respiratory system by blocking the tubes that act as a passage carrying the air inside and out of the lungs. As a result,
- A person may suffer from lung infections frequently.
- There may be difficulty in breathing, stuffy and blocked nose, or wheezing.
- Some people may also suffer from a chronic cough with a thick sputum.
Left untreated the complications can worsen resulting in

Nasal polyps, Chronic infections, Hemoptysis (there is blood while coughing), and Pneumothorax (air fills up in the space bifurcates the chest wall from the lungs).

In severe cases, there may be a respiratory failure.

Cystic fibrosis can also trigger fertility problems (both in males and females).

Cystic Fibrosis- Causes and Symptoms!

Child nutrition from age 6 months to 5 years Growth and development of a child depends on the nourishment received by the child right from birth. Healthy diet and proper eating habits are essential to be inculcated in a child as early as possible. A balanced diet given to the child at the earliest provides all nutrients required for adequate growth and development. Nutritional value of every food item introduced in the child s diet should be gauged prior and then given to the child. 

Nutritional requirement of children varies in accordance to the age group. It is necessary that the parents should have knowledge about the age-specific requirements of the diet, which will benefit the child in their growing years. 

Following is the ideal child nutrition ranging from the age group of 6 months to 5 years. 

1. 6 months to 12 months

A. Right from the birth of a newborn child, it is necessary to begin breastfeeding for the baby. It should begin within an hour of the child s birth. It is the ideal way of providing proper nutrition to the child. 

B. Breastfeeding is beneficial by providing nourishment and also by improving the immunity of the baby. 

C. From birth to 6 months, only breastfeeding is advised. It is a critical source of nutrition for the child even during illness. 

D. After the baby turns 6 months old, solid food can be introduced in the child s diet.

E. Breastfeeding can be continued and supplemented with other food items.

F. Usually, fruit juices are introduced first in the diet.

G. Feeding bottle should be avoided and the child should be fed with a spoon and cup. Proper hygiene and good handling of the food is required. 

H. It is necessary to wipe the gums and developing teeth clean with a wet gauge to prevent any decay that can be caused by sticking of the food on the teeth surfaces fed to the child.

2. 1 year to 3 years

A. Children in this age group can tell when they feel full after feeding. It is necessary to listen to their demand for food and also avoid overfeeding children.

B. This age group requires children to eat all types of nutrients, so parents should focus on providing a variety of food items to replenish their child s nutritional requirements.

C. Children in this age group require fat-rich foods and should be given dairy products for calcium requirements.

D. Processed foods should not be given to children in this age. Calories intake should be monitored to the optimum level. 

E. Since children at this age are involved in activities like walking, running around and playing it is essential to keep feeding them at regular intervals to maintain the energy levels of their bodies.

3. 3 years to 5 years.

A. Children belonging to this age group require to eat a well-balanced, nutrient rich diet. 

B. Grains should be included on a routine basis. They provide the child with carbohydrates, fibers and minerals. All these nutrients provide energy to the child s body. 

C. Inclusion of whole wheat grains provides fibers in adequate quantity. 

D. Refined foods should be avoided, whole grain breads should be included in the diet. 

E. Fruit intake should be increased, as they are an important source of various vitamins. Fresh fruit should always be preferred over juices for growing children. 

F. Sugar intake should be kept to a minimum quantity, since refined sugars do more harm to the child s health than any good. 

G. Vegetables should form a considerably greater part of the child s daily diet, with the inclusion of a variety of vegetables. 

H. Protein sources of food include meat, poultry, pulses, beans and nuts. Along with protein, these food items also provide iron, zinc and minerals to the body. 

Apart from the above specified food items, daily intake of milk is necessary for children of growing age. It provides the body with sufficient calcium to facilitate bone growth in growing children. Also, nuts like walnuts, almonds, cashews are advised to be given to the children daily.

Nutrition Tips For Children From Age 6 Months To 5 Years!

The appendix is a small, finger-shaped pouch attached to the large intestine in the right belly area. It is a vestigial organ as it has no specific role to play in humans, but the organ is still seen, though in a very small size compared to the earlier living beings in the evolutionary chain. Acutely inflamed appendix is the most common cause leading to it removal, often seen in the ages of 10 to 19.

Causes: the appendix gets infected by two main reasons - general infection in the abdomen that reaches the appendix or blockage of the appendix leading to inflammation and swelling within it. The appendix is a blind pouch, and there is a good chance for its blockage from food particles, lymphatic tissue, or even sometimes feces. Some of the potential risk factors for appendicitis include a diet low in fiber, high in sugar, gut flora, and family history.

Symptoms/diagnosis: in adults, the appendicitis has very characteristic symptoms including acute pain in the right upper part of the belly associated with fever and vomiting. However, in children, the pain may not be as tell-tale a sign but is still quite diagnostic of appendicitis. However, presence of the following symptoms together is surely indicative of appendicitis.
1. Right abdominal pain, especially rebound tenderness, where pressure placed in the right upper part of the belly and released leads to excruciating pain.
2. Fever, nausea, and vomiting
3. Abdominal fullness or bloating
4. Elevated white blood count (as with most infections)
Additionally, the younger the child, the symptoms are not very clear, but ultrasound will confirm the diagnosis. The inflamed, enlarged appendix will be visible on the images and could be surrounded by free fluid. Ct scan also can be considered if required to confirm the diagnosis.

Treatment: as noted above, children present with symptoms that do not pinpoint to appendicitis. Treatment usually takes two routes:

If diagnosed as appendicitis before rupture, then surgical removal is the best method to contain its symptoms. Other symptoms like fever and nausea and vomiting usually subside a couple of days after the surgery.
If the appendicitis goes unnoticed and ruptures, then the intestinal cavity can get infected, which is called peritonitis. Earlier, the preferred approach was to control the infection and then go for removal. However, lately, removing the appendix followed by antibiotics to control the infection is the preferred approach.
The prognosis and recovery from appendicitis is very good. Deaths have occurred only in very small infants, where they are not able to pinpoint the area and therefore it can go undiagnosed, leading to rupture and subsequent death.

Early identification is the key to proper identification, immediate treatment, and complete recovery from appendicitis.

Appendicitis in Children

Many women develop uterine fibroids by the time they hit the age of 50 years and above. These are non-cancerous growths that may occur in the uterus. Most women go through severe bleeding and pain as well as discomfort as a result of these fibroids. Age, family history of the same condition, obesity or being overweight, eating habits and even ethnicity play a large role in deciding the risk of each individual patient. These fibroids can grow in the submucosal, intramural and subserosal areas.

Following are the common side effects of uterine fibroids:

    Frequent urination: Due to the pressure of the fibroids on the uterus, the patient may experience a constant feeling of fullness in the lower pelvic area of the body, which may lead to frequent filling of the bladder. This gives rise to frequent trips to the washroom for urination. 
    Heavy Bleeding: Severe bleeding is one of the most common causes of the presence of these kinds of fibroids. The patient may experience a lot of bleeding during menstrual periods, as well as pain and cramps the rest of the time. The periods will also be very painful when there are fibroids in the uterus or the uterine lining.
    Painful Intercourse: It is a well-known fact that any kind of infection or growth as well as sores and other such ailments can lead to vaginal dryness as well as pain during sexual intercourse. This is true for uterine fibroids as well, which can lead to severe pain during sexual activity. These fibroids can also give rise to pain in the lumbar or lower back region.
    Abdomen Swelling: The abdomen may go through significant swelling in such a condition and the patient may even look like she is pregnant. The growth can push the shape of the abdomen outwards and create a full feeling.
    Pregnancy Complications: The presence of uterine fibroids can give rise to several complications during pregnancy and even after child birth. One of the most common problems in this case is bleeding, followed by more severe outcomes like miscarriage. The women suffering from uterine fibroids are at greater risk of undergoing a caesarean section for the delivery of the baby. The baby may also be born breech and a premature delivery may take place. 
    Infertility: This is also a rare side effect of the uterine fibroids and is generally seen only in very severe cases. 
    Cancer: Only one in every 1000 cases might transform into malignant tumours. These uterine fibroids are generally known to be non-malignant. 

Any symptoms must be reported to a gynaecologist at the earliest to avoid any serious complications.

Common Side Effects of Uterine Fibroids

Bedwetting or nocturnal enuresis, refers to the unintentional passage of urine during sleep. Enuresis is the medical term for wetting, whether in the clothing during the day or in bed at night. Another name for enuresis is urinary incontinence. For infants and young children, urination is involuntary. Wetting is normal for them. Most children achieve some degree of bladder control by 4 years of age. Daytime control is usually achieved first, while nighttime control comes later.

The age at which bladder control is expected varies considerably. Some parents expect dryness at a very early age, while others not until much later. Such a time line may reflect the culture and attitudes of the parents and caregivers.

Factors that affect the age at which wetting is considered a problem include the following:

The child's gender: Bedwetting is more common in boys.
The child's development and maturity
The child's overall physical and emotional health. Chronic illness and/or emotional and physical abuse may predispose to bedwetting.
Causes

No one knows for sure what causes bed-wetting, but various factors may play a role:

A small bladder: Your child's bladder may not be developed enough to hold urine produced during the night.
Inability to recognize a full bladder: If the nerves that control the bladder are slow to mature, a full bladder may not wake your child, especially if your child is a deep sleeper.
A hormone imbalance: During childhood, some kids don't produce enough anti-diuretic hormone (ADH) to slow nighttime urine production.
Stress: Stressful events, such as becoming a big brother or sister, starting a new school, or sleeping away from home, may trigger bed-wetting.
Urinary tract infection: This infection can make it difficult for your child to control urination.
Sleep apnea: Sometimes bed-wetting is a sign of obstructive sleep apnea, a condition in which the child's breathing is interrupted during sleep.
Diabetes: For a child who's usually dry at night, bed-wetting may be the first sign of diabetes.
A structural problem in the urinary tract or nervous system. Rarely, bed-wetting is related to a defect in the child's neurological system or urinary system.

Symptoms

Wetting during the day
Frequency, urgency, or burning on urination
Straining, dribbling, or other unusual symptoms with urination
Cloudy or pinkish urine, or blood stains on underpants or pajamas
Soiling, being unable to control bowel movements
Constipation
Most kids are fully toilet trained by age 5, but there's really no target date for developing complete bladder control. Between the ages of 5 and 7, bed-wetting remains a problem for some children. After 7 years of age, a small number of children still wet the bed.

When to see a doctor: Most children outgrow bed-wetting on their own, but some need a little help. In other cases, bed-wetting may be a sign of an underlying condition that needs medical attention.

Consult your child's doctor if: 

Your child still wets the bed after age 7
Your child starts to wet the bed after a few months or more of being dry at night
Bed-wetting is accompanied by painful urination, unusual thirst, pink or red urine, hard stools, or snoring
Self-Care at Home-
Here are some tips for helping your child stop wetting the bed. These are techniques that are most often successful

Reduce evening fluid intake.
The child should urinate in the toilet before bedtime.
A system of sticker charts and rewards works for some children.
Make sure the child has safe and easy access to the toilet.
Some believe that you should avoid using diapers or pull-ups at home because they can interfere with the motivation to wake up and use the toilet.

Bedwetting - 7 Possible Reasons Behind It

Upper respiratory infection (URI) is a condition, which involves illness, mainly caused by critical infection in the upper respiratory tract. This region includes the pharynx, larynx, nose and sinus. This infection causes diseases, such as tonsillitis (tonsils get inflamed), pharyngitis (causes sore throat) sinusitis (nasal passage becomes inflamed), laryngitis (voice box in your throat gets inflamed) and common cold.

Causes of upper respiratory infection (URI):
1. Both virus and bacteria cause upper respiratory infection (URI). The most common form of virus causing this infection is known as 'rhinovirus.'

2. The immune system of young adults and children are often very vulnerable. Hence, they are more likely to develop upper respiratory tract infection.

3. URI is also contagious and airborne in nature. So if a person comes in contact with an infected person suffering from URI, he/she is likely to develop this infection.

4. Not washing hands before meals can also cause upper respiratory infection because the virus can be transferred easily to the mouth and can travel into your system.

5. If you have any lung problem or heart disease, you are more likely to be susceptible to upper respiratory infection.

6. Those who already have inflamed tonsils can trigger tonsillitis by drinking any cold or spicy beverage like ice-creams or cold milkshakes.

7. Exposure to some flu or cold can cause pharyngitis. It can also be caused by second hand smoking.

8. Birth defects or structural defects in the nasal cavity or nasal polyps can cause sinusitis. Sometimes the inside part of the nose may get swollen due to common cold and block your ducts. This is a common cause for sinusitis.

Symptoms of acute upper respiratory infection:
1. Congestion in the lungs or nasal area.
2. Whooping cough
3. Running nose due to common cold.
4. Feelings of fatigue and lethargy throughout the day.
5. Your body will start aching without engaging in any physical exercise.
6. You can also lose consciousness in severe respiratory tract infections.
7. Difficulty in breathing.
8. Oxygen levels in blood drop down drastically.

Sometimes in worse cases, acute upper respiratory tract infection (URI) can also cause respiratory failure, respiratory arrest and congestive heart failure. Therefore, it is necessary to book an appointment with a doctor as soon as you start experiencing the above symptoms.

Acute Upper Respiratory Infection: Causes and Symptoms

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