Blood is one of the most crucial elements of human existence. It works as a commute for oxygen and various nutrients in reaching the cells. These functions make blood a vital source for the body to operate. That said, india needs 38, 000 blood donations every day, which adds up to 5 crore units required in a year. However, only 2.5 crore units are available against the huge unfulfilled numbers. Hence, it is essential to recognize the importance of blood donation.

 

Why is blood donation important?

While blood donations are essential to help people with surgeries, they are equally vital during cancer treatments, chronic diseases, and gruesome injuries. Moreover, they also benefit the donors in a significant way.

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Types of blood donations

Blood donations are of several types through which a single donor has the potential to help nearly three people.

 

Whole blood donation

It is the most common process of donating blood. One pint of blood collected supports numerous patients in the process. It is, then, divided into different components that aid the donation.

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Plasma donation

The process of plasma collection is carried out through a method called apheresis. It divides plasma from other blood components. Its blood clotting abilities help trauma patients and people undergoing cancer treatment.

 

Platelet donation

The collection of platelets is also done using apheresis. Once identified in the donor s blood, the rbcs and the donor gets other fluids back. Cancer patients are the chief beneficiaries of platelets as they play a prominent role during cancer treatments.

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Double red cell donation

Red blood cells are also collected through the apheresis process. It helps donors to donate twice the dose of a whole blood donation. One can help a patient suffering from blood loss using this method.

 

Advantages of blood donation

Blood donations have several advantages that people should know. They help fight many severe health conditions in the human body. Some of them include-


	
	Loss of blood due to internal or external injuries caused by accidents
	
	
	Sickle cell disease or other abnormalities that affect the blood
	
	
	In the treatment of cancer
	
	
	Cardiovascular or orthopedic surgeries
	
	
	Blood disorders
	
	
	Transplant processes
	
	
	Treatments involving plasma
	


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Covid-19

According to food and drug administration (fda) reports, patients who have recovered from covid-19 can help others by donating blood plasma. They contain antibodies that fight the infection, helping their body fight the virus.

 

Benefits for the donor

Even the donors receive many health and social benefits because of blood donation. Where donated blood saves lives, experts suggest that donors can also benefit from the same. Some of these advantages include:

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	Boosting cardiovascular health
	
	
	Maintaining blood pressure
	
	
	Contributing to the community
	
	
	Reducing the iron levels
	
	
	Improving overall health
	



 

Why Blood Donation Is Important?

Hepatitis is a medical condition that occurs when an infected person's liver gets inflamed. There are several reasons that can result in hepatitis, including viral infections, heavy alcohol abuse, and autoimmune conditions.

 

Mostly, hepatitis is a result of an infection caused by a virus. Such a condition is called viral hepatitis. Today, we will talk about the three most common types of viral hepatitis diseases:

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	Hepatitis a
	
	
	Hepatitis b
	
	
	Hepatitis c
	


 

Hepatitis a

Hepatitis a is a result of hepatitis a virus infection in a person and is relatively uncommon.

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Regions, where hepatitis a is more common, are:

 


	
	Africa
	
	
	Asia
	
	
	Central and south america
	
	
	Eastern europe
	


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How it is transmitted

Hepatitis a virus can be present in the fecal matter and blood of an infected person. Hence, it is transmitted via the oral route, involving ingestion of the virus into a person through the feces.

 

Different ways you can get hepatitis a infection are:

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	Having in-person contact with a hepatitis a-infected patient
	
	
	Sexual contact with a person who hosts the virus
	
	
	Consuming contaminated food or drink
	
	
	Eating undercooked shellfish
	
	
	Being near contaminated toilets and diaper changing areas
	


 

Hepatitis b

Hepatitis b is caused by the hepatitis b virus.

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Regions, where hepatitis b is more common, are:


	
	Western pacific region
	
	
	African region
	


 

How it is transmitted

You can contract hepatitis b virus through direct contact with blood or bodily fluids of hepatitis b infected person.

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Different ways you can get hepatitis b infection are:

 


	
	Sexual contact with someone with hepatitis b virus infection
	
	
	Sharing injections and other tools
	
	
	Born to hepatitis b infected parent
	
	
	Direct contact with blood of an infected individual
	
	
	Sharing personal belongings and toiletries like razors or nail clippers.
	


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Hepatitis c

Hepatitis c occurs by the infection caused by hepatitis c virus.

 

Regions, where hepatitis c is more common, are:


	
	Eastern mediterranean region
	
	
	European region
	


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How it is transmitted

Hepatitis c virus is spread through blood and other bodily fluids.

 

Different ways you can get hepatitis c infection are:

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	Sharing injections
	
	
	Born to hepatitis c mother
	
	
	Sexual contact with an infected person
	
	
	Piercing or tattooing with unsterilized equipment
	
	
	Injuries with needles pr blades
	
	
	Sharing razors, or toothbrushes
	


The A, B and C of Hepatitis

Diabetes is a common chronic condition that results from excessively high blood glucose. In this condition, either the pancreas fail to produce enough insulin, or your body does not utilize insulin produced by pancreas properly. This might lead to cardiovascular problems and neural problems, as well as health problems like ;depression and ;anxiety. Recent studies reveal that diabetes may have an impact on your reproductive health too.

Effects on men

A common problem that affects men s sexual life is erectile dysfunction. Diabetic men face this as they have low testosterone levels and are unable to maintain an erection during sex. For an erection, constant blood flow is necessary inside the penis. However, as diabetes disrupts the blood flow and damages the blood vessels, men are not able to achieve an erection.

Furthermore, diabetes also damages the arteries and nerves, which again, disturbs the blood flow to the penis. This also causes erectile dysfunction. Other factors that can cause sexual complications among men are- ;


	
	Diabetes-induced obesity
	
	
	High blood pressure
	
	
	Retrograde ejaculation ;  refers to a condition where semen is ejaculated to your bladder, but not through your penis
	


Effects on women

For women, during menopause, blood ;sugar levels may drop due to diabetes. Besides, high blood sugar levels damage the nerves of a woman. This may hinder the ability to feel aroused during sex and lowers sexual stimulation. This reduces their capability to achieve orgasm.

Another common issue among women with diabetes is ;vaginal dryness. This causes a lack of lubrication in the vagina that makes sex painful. Damage to the nerves that lubricate the vagina may be the reason for this. During menopause or after menopause, it can be due to low oestrogen.

Diabetes is more likely to cause vaginal infections such as yeast infections and urinary tract infections. Both of these cause pain during sexual intercourse. If the nerves of the bladder are damaged, it can lead to urinary incontinence ;while sex.

There are certain medications and therapy that may help control diabetes. Additionally, changes in lifestyle such as eating healthy, exercising daily etc. Will enhance your well-being that will significantly improve your blood glucose levels   and in turn, your sex life.

Know How Diabetes Impacts Reproductive Health

What are the different types of sickle cell disease?

Sickle cell disease or sickle cell disorder is a term often used to talk about a group of diseases affecting hemoglobin. It is the oxygen-carrying element of blood that makes up 2 alpha globins and 2 beta globins. Sickle cell disease happens due to beta-globin mutation and depending on the abnormality in mutation.

Types-
Sickle cell diseases can be of many types depending on the gene mutation in the blood. Some of the common types are-

Sickle hemoglobin s disease (ss)
Hemoglobin ss disease or sickle cell anemia is the most popular type of scd. It takes place when hemoglobin s gene mutation is inherited from both mother and father. In simple words, it happens when the child inherits one substitution beta-globin gene from each parent. In this type, the body only produces hemoglobin s. It is mostly found in people of african and indian origin.

Sickle hemoglobin- c disease (sc):
Patients with sickle hemoglobin sc disease have a moderately dissimilar swapping in their genes of beta-globin. Here, both hemoglobin c and hemoglobin s are inherited from each parent. It may cause similar symptoms like anemia but remains relatively l. People of west african and mediterranean origin are more prone to this.

Hbs beta-thalassemia
People with this type of scd inherit one sickle cell gene s and one gene for beta-thalassemia from each parent. Zero and plus are the two common types of beta-thalassemia. While beta 0 thalassemia usually takes a severe form, beta + thalassemia is a milder form of the disease.

Sickle beta-zero thalassemia
Beta-zero thalassemia takes form when the child inherits the beta s gene from one parent and beta 0 thalassemia gene mutation from the other. With similar symptoms to anemia, it is a slightly severe form of beta-thalassemia.

Sickle beta-plus thalassemia
Substitutions in both beta-globin genes take place in patients with sickle beta thalassemia (sb) disease. This may even lead to the requirement of blood transfusion if no normal beta globin is produced. Mediterranean and caribbean people are more likely to have this disorder.

Hemoglobin sd, hemoglobin se, and hemoglobin so
These are the few rare and not less common types of sickle cell diseases. They are also less severe. People with these forms of scd inherit one sickle cell gene s and one gene from uncommon hemoglobin (d, e, or o) from each parent.

Sickle cell trait
Hbas
People with sct have one sickle cell gene s and one normal gene a from both mother and father. Ones with this disorder show few to no signs of the disease and usually spend a normal life. However, the risk to their future generations still exists.
 

What Are The Different Types Of Sickle Cell Disease?

Surprising benefits of donating blood

Blood is that element in the human body that can't be manufactured. Hence, it makes blood donation a very significant phenomenon. It benefits the patients, the donors, society, and the overall medical ecosystem. However, people are not particularly aware of some of the benefits of donating blood. While some of them are necessarily good for your overall health, some can even surprise you.

Benefits

Potentially reveal health issues
Donating blood gets your vitals checked to make sure you are adequately fit for the procedure. Hence, it can be a process to keep your overall health checked. Your pulse, blood pressure, and hemoglobin check can ensure that you are free of any chronic illness. Usually, blood low in iron is not taken for donation. As a result, blood donation can find health issues that can be eradicated from the roots.

Reduce harmful overload of iron
Iron overload in the body causes a condition called hemochromatosis. Although this condition is not a usual phenomenon in india, it is important to detect it at the earliest. Blood donations help eliminate the excess iron from the body through red blood cells.

Cardio and vascular health
Regular blood donation maintains low blood pressure and keeps the risk of heart attacks at bay. According to a study, donating blood reduces the chance of heart attacks by 88 percent. High hemoglobin and high iron stores are checked by blood donations that have to do with blood clots and strokes.

Reduce the risk of cancer
A high concentration of iron in the body can cause free-radical damage. It increases the risk of cancer in the lungs, liver, colon, and throat due to the lowering of oxidative stress. Thus, regular blood donations make sure that the risk of cancer and mortality is lower.

Liver stays healthy
Excess iron in the body gets stored in the liver, heart, and pancreas leading to a risk of cirrhosis or liver failure. Various health ailments related to the liver are prevented by donating blood and getting rid of the extra iron in the body.

Help your mental state
With several physical benefits, there are also some psychological edges. As donating blood directly or indirectly helps a patient, it gives a sense of pride and satisfaction. Making a difference in society feels extremely fulfilling and that keeps you in an elated state. Hence, blood donation is equally healthy for your body and mind.

Surprising Benefits Of Donating Blood

Abstract

Background: it is essential to have an understanding of life expectancy and risk factors among patients with sickle cell disease (sickle cell anemia, hemoglobin diseases, and thalassemias). These are required to counsel the patients, target treatment, and plan the right clinical trials.

 

Methods: a research followed 3764 people ranging from birth to 66 years of age and suffering from scd. The procedure was done to understand the life expectancy and calculate the average age at death. Moreover, the study understood the reasons for the death in all 209 adults. It used the proportional-hazards regression analysis to know the risks for an untimely death in adults with sickle cell anemia.

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Results: when the results for young kids and adults with sickle cell anemia were observed, it was found that the average age at death was 48 for women and 42 for men. Moreover, suffering from hemoglobin c disease had an average mortality age of 60 for men and 68 years for women.

 

In people with sickle cell disease, 18% of deaths took place in patients with mainly renal organ failures. 33% of the tested patients were medically free of organ failures but episodes of pain crisis took their life. Out of these patients, 78% experienced chronic pain, chest syndrome, or both, while 22% suffered a stroke that took their lives.

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Clinical modeling showed that people with sickle cell anemia faced acute chest syndrome, seizures, kidney failure, a white-cell count of over 15, 000 per cubic mm, and a low hemoglobin level were related to a risk of early death.

 

Conclusions: results suggested that 50% of patients with sickle cell anemia lived beyond the age of 50. A huge share of those who lost their lives suffered no noticeable chronic organ failure. However, most of them died due to acute episodes of pain or stroke. Early death was seen highest among patients who had symptomatic disease. High levels of fetal hemoglobin suggested improved chances of survival and are assumably a credible source to foresee the risks and other factors related to adult life expectancy.


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Life Expectancy And Risk Factors Involved In Sickle Cell Disease

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