World sickle cell day is observed annually on the 19th of june to raise awareness of sickle cell-related diseases. It is observed to increase people's knowledge and the understanding required to face the challenges posed by the disease.


 

What is sickle cell disorder (scd)?

Sickle cell disorders or sickle cell diseases are genetic blood disorders that cause an abnormality in the red blood cells. The rbcs turn into sickle-shaped cells that stick together and block the blood flow in the body.


 ;

Types

There are four major classifications of sickle cell diseases-


	
	Hemoglobin ss disease
	
	
	Hemoglobin sc disease
	
	
	Hemoglobin sb+ thalassemia
	
	
	Hemoglobin sb 0 thalassemia
	



 

Symptoms

One can start noticing symptoms of sickle cell in a patient at around 6 years of age. However, they can differ from person to person. Some of the most typical symptoms are-

 ;


	
	Anemia
	


A shortage of red blood cells occurs due to the excessive early dying in 10-20 days. It leads to an oxygen shortage in the body.


	
	Excessive pain
	


Blockage of blood flow due to the change in shape leads to periodic cycles of pain in the body.


	
	Swelling in the body
	


As the blood circulation becomes irregular, swelling becomes a regular phenomenon.


	
	Infections
	


Sickle cell can be damaging to the spleen. It increases the risk of ailments in the body that can be prevented only by antibiotics.


	
	Delayed puberty
	


Oxygen and nutrients carried by the blood are required for growth. As a reason, irregular blood flow can lead to slow growth or delay in puberty.


	
	Vision issues
	


Infected blood vessels carrying blood to the eyes can cause damage to the retina. It can lead to visual problems.


 

Traits and treatment

As sickle cell is genetic, it is suggested to take a test that can detect any trait of the disease. It can prevent any life-threatening risks to the newborn. However, we don't have a complete cure for sickle cell disorders. There are preventive measures that reduce the adversity of the disease to an extent. Procedures like blood transfusions help greatly in minimizing the effects of the disorder.

World Sickle Cell Day: Know All About Sickle Cell Disease

Kidney - prolonged periods of stress can indirectly hurt your kidneys. So you need to be stress free to keep your kidneys healthy.

Stress And Kidney Failure: Are They Connected?

Blood donation is a process that is carried out when a person voluntarily offers for blood to be extracted from his body. There are countless myths about blood donation that need to be squashed and awareness is the only way of doing it.

While blood donation brings multiple health benefits to both the donor and recipient, some facts are known to only a few. These facts will not only open doors to endless possibilities, but will make people feel confident about it.

Facts

Here are some lesser-known facts about blood donation- every person should know-

 


	
	Approximately 112.5 million units of blood are collected from blood donation globally.
	
	
	Around 30 million units are transfused annually.
	
	
	Any person in sound health, at least 18 years old, and weighing at least 45 kilograms can donate blood every 56 days.
	
	
	Your one unit of donated blood can save up to 3 lives.
	
	
	A, b, ab, and o are the primary blood groups. While ab is a universal recipient, o negative is a universal donor.
	
	
	The blood donation process normally takes less than 10-12 minutes.
	
	
	Donating blood does not make you physically weak or decrease your strength.
	
	
	Only 1% of india's population donates blood each year, leading to an annual deficit of two million units.
	
	
	All donated blood units are tested for diseases like hepatitis b, hepatitis c, hiv, and syphilis before transfusion.
	
	
	Red cells, plasma, cryoprecipitate, and platelets are the various types of transfusable elements derived from the blood. The procedure takes place using a method called apheresis.
	
	
	Red blood cells carry oxygen to the organs.
	
	
	Red blood cells survive for about four months in the system of circulation.
	
	
	Platelets encourage blood clotting and provide leukemia patients and other cancer patients with better treatment.
	
	
	Plasma is a pale yellow combination of proteins, salts, and water.
	
	
	Plasma is 55 percent of the volume of blood and 90 percent water.
	
	
	White cells are the chief defense of the body against infections.
	
	
	There is no alternative for blood donation as blood cannot be manufactured.
	
	
	You cannot contract aids or other infectious diseases due to blood donation.
	


Lesser Known Facts About Blood Donation

Thyroid cancer refers to the type of ;cancer that originates in the thyroid gland. Cancer develops when the cells in your thyroid gland begin multiplying uncontrollably to form malignant tumours.

What leads to the development of cancer in the thyroid glands is not clearly known. However, a combination of environmental factors and genetics could be a leading cause of cancer.

Thyroid cancer is the sixth most common cancer in women, and usually affects those in their 20s and early 30s.

Types of thyroid cancer

Four types of thyroid cancer are prevalent, which are  


	
	Papillary thyroid cancer   ;this is the most common type of thyroid cancer. Cancer typically develops in one of the two lobes in the thyroid gland, and gradually spreads to the lymph nodes in your neck.
	
	
	Follicular thyroid cancer   ;the second most common type is the follicular thyroid cancer. Here the disease spreads to other body parts and organs, like the bones or lungs rather than the lymph nodes.
	
	
	Medullary cancer   cancer starts from the c-cells of the thyroid gland, which usually produce a hormone called ;calcitonin. The disease can spread to the lungs, liver, or lymph nodes even before a nodule is discovered.
	
	
	Anaplastic thyroid cancer   this form of cancer is rare but aggressive. It develops from an existing follicular or papillary cancer and spreads to other parts of the body faster than any other type of thyroid cancer.
	


Symptoms to watch out for

The symptoms of thyroid cancer depend on its type. Although there are no observable symptoms in the initial stage, you might be able to spot some changes in your body as cancer progresses. These symptoms include:


	
	A lump or mass in the neck that can be felt through the skin
	
	
	Change in voice   ;hoarseness
	
	
	Pain in the throat and neck
	
	
	Difficulty in swallowing
	
	
	Swelling of the lymph nodes in your neck
	


Diagnosis and treatment

The following tests/procedures can help detect thyroid cancer early  


	
	Blood test
	
	
	Ultrasound
	
	
	Biopsy
	
	
	Imaging tests
	
	
	Genetic testing
	
	
	Pet scan
	


Once cancer is diagnosed, appropriate treatment will be prescribed depending on the stage. Primary treatment options include  


	
	Chemotherapy ;  medications are infused through veins to kill cancer cells
	
	
	Radiation therapy   high-energy radio beams are directed to destroy cancer cells
	
	
	Radioactive ;iodine   large doses of radioactive iodine are given orally
	
	
	Targeted therapy   medications are given to attack certain vulnerabilities in the cancer cells
	
	
	Surgery ;  complete or partial removal of the thyroid gland or the lymph nodes
	


Prior to the treatment, your doctor will discuss the treatment plan specific to your diagnosis. Thyroid cancer is curable if detected at the right time. Therefore, do not lose hope and consult a specialist as early as possible.

Thyroid Cancer: Causes, Symptoms, And Treatment

Preeclampsia is a condition that affects women during pregnancy. It is characterized by increased blood pressure and high levels of protein in the urine. Women with preeclampsia also experience swelling in the feet, legs, and arms.

Researchers suspect that excessive body fat or poor nutrition are the primary contributors to preeclampsia and eclampsia.

If left undetected, preeclampsia can lead to a more severe complication, known as eclampsia. Eclampsia can put you and your baby at risk, and can even lead to death (in rare cases).

How do preeclampsia and eclampsia affect the mother?

Preeclampsia and eclampsia can cause a host of complications for the mother, such as the following  

Hellp syndrome   hellp syndrome refers to three different conditions   low platelet count, elevated liver enzymes, and haemolysis. This generally occurs late in pregnancy and affects the processing of rbc, functioning of the liver, and blood clotting.

Seizures

Heart and renal failure

Water in the lungs

Bleeding from the liver

Reversible blindness

Effects of preeclampsia and eclampsia on the baby

Preeclampsia can lead to problems with the placenta in the initial stage of pregnancy. This may pose risks, including the following to the baby  

Lack of nutrients and oxygen, which may prevent the foetus to grow properly

Preterm birth

Stillbirth   this happens when the placenta is separated from the uterine wall

Infant death

Stillbirths are more common when the mother has suffered from a severe form of preeclampsia, like hellp syndrome.

Preeclampsia and eclampsia are linked to a myriad of health issues and life-long challenges for prematurely born babies. These may include cerebral palsy, learning disorders, epilepsy, deafness and blindness.

There is no particular cure for preeclampsia and eclampsia. Treatment, however, depends on how close you are to your due date, and how much the foetus has developed. In the case of mild preeclampsia, your doctor may recommend resting, healthy eating   that limits salt intake   and regular prenatal checkups.

Effects Of Preeclampsia And Eclampsia On You And The Baby

When abnormal cells grow inside the brain and are in the form of a mass the condition is called a brain tumour. There are various types of brain tumours that exist. Some of the brain tumours which exist are malignant or cancerous while other may be non-cancerous. A brain tumour can begin in any part of the brain and spread to other parts of the body or vice-versa. The growth rate of brain tumours is different for each individual suffering from it. As per studies, every 2 in 1, 00, 000 people are said to be affected by a brain tumour in india. However, it may come as a relief to some as not all brain tumours are cancerous or life-threatening. Some are benign tumours and seldom pose any threat to the affected individual.

 

Types of brain tumor

Brain tumours may be primary or secondary.

Primary brain tumour

In this type of brain tumour, the abnormal mass of cells that originated in the brain does not metastasize to the other organs. Based on their location in the brain, the primary brain tumours may be of the following types.


	
	Gliomas: one of the most common types of primary brain tumours, gliomas can have their origin in the spinal cord or the brain. Some of the common types of gliomas include astrocytomas (originates in the cerebrum of the brain), glioblastomas (these tumours form from the astrocytes which form the supportive tissues of the brain), ependymoma (these develop from the ependymal cells which are present within the cns), oligodendrogliomas (these tumours are found to arise from the oligodendrocytes).
	
	
	Schwannomas: also called acoustic neuromas, these primary brain tumours form on the nerves that play an important role in regulating the balance and hearing from the inner ear to the brain.
	
	
	Meningiomas: these types of tumours are usually benign and have their origin in the meninges (membranes surrounding the spinal cord and the brain).
	
	
	Primitive neuroectodermal tumours (pnets): primitive neuroectodermal tumours (pnets) are rare malignant tumours that originate from the fetal (embryonic) cells in the brain.
	
	
	Pituitary adenomas: as the name suggests, these tumours arise from the pituitary gland located at the base of the brain.
	
	
	Medulloblastomas: common among children, these malignant primary tumours develop in the brain (lower back) and gradually spread via the spinal fluid.
	


Other types of primary brain tumours include craniopharyngiomas and germ cell tumours.

Secondary brain tumours ;

Unlike the primary brain tumours, these tumours have their origin in the other body parts and organs (mostly in the lungs, skin, colon, breast, and kidney) and then gradually metastasize to the brain. Secondary brain tumours are found to be more common.

 

What Are The Different Types Of Brain Tumours?

Don't wait any longer, manage your Pediatric Endocrinologist online with a Lybrate doctor today

Consult for Pediatric Endocrinologist - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES