What is Parkinson s disease?
Parkinson s disease is a progressive and degenerative disorder of the Central Nervous System that mostly affects older people. It is a chronic disease and the symptoms develop over a period of time. The characteristic symptoms of Parkinson s are rigidity, shaking, bradykinesia (slowness in movement) and shuffled gait. Anxiety and depression also seem to be common in advanced stages of Parkinson s disease. In addition to the motor symptoms, the cognitive function of the brain is also compromised.

Degeneration of the nerve cells in the substantia nigra of the brain results in the reduction in production of dopamine which is a neurotransmitter in the brain. Neurotransmitters relay impulses from one nerve to the other. This is what is mainly responsible for the motor symptoms in Parkinson s. Although, Parkinson s is not a curable disease, it can be controlled and the progress of the disease can be kept in check with certain medications.

What causes Parkinson s disease?
The cause of Parkinson s is mostly idiopathic, i.e. the cause is unknown and is not specific. However, there have been cases which show that it can be attributed to factors such as genetic and environmental factors.
What are the symptoms of Parkinson s?

The symptoms of Parkinson s can be classified as Motor symptoms and Non-motor symptoms:

Motor Symptoms 

Bradykinesia: Slow movement
Tremor of limbs
Rigidity or stiffness of trunk and limbs
Impaired balance and difficulty in coordination or postural instability
Non-motor Symptoms 

Depression
Anxiety and fear
Loss of energy and fatigue
Constipation
Excessive salivation
Weight gain or weight loss
Cognitive problems such as difficulty in remembering, confusion, dementia
Parkinson s disease is not curable, but when detected early, medicines are prescribed to give symptomatic relief. Dopamine substitutes are prescribed to the patient to relieve the motor symptoms.

Parkinson's Disease - Understanding The Motor & Non-motor Symptoms!

If you are being treated for Parkinson's disease. How can you maximize the effect of Levodopa? The effect of levodopa can be maximized by increasing its absorption from the digestive system. In particular, taking levodopa on an empty stomach is very important. 

Take on an empty stomach: Do not eat anything 1 hour before taking levodopa. Do not eat anything for at least 30 minutes and if possible 1 hour after taking it. Take the pill with 2 glasses of water so that it can dissolve. If taking the levodopa on an empty stomach makes you nauseous, confirm that your medication has the right amount of carbidopa in relation to the levodopa (25%). If you continue to feel nauseous, you can eat a piece of white bread around the time that you take levodopa. Do not apply any butter, yogurt, cheese or similar high protein spreads. Protein can drastically decrease the absorption of levodopa. 
Get your constipation treated: This is critically important too. Being constipated can slow down the passage of levodopa through the digestive system. In most patients, drinking adequate water and taking stool softeners is helpful. 
Get your ulcer treated: It can be difficult to recognize that you have a gastric ulcer. However, if you have a burning sensation in your stomach at any time, or belch frequently, you may have a gastric ulcer. If you think you have an ulcer you should get tested (there is a simple breath test now) and treated with antibiotics (not antacids!) 
Do not take levodopa with iron tablets: The iron binds to levodopa and prevents its absorption. Keep a gap of at least two hours between these two medications. 
Try taking levodopa with orange juice and carbonated water (soda): Mix equal quantities of orange juice and carbonated water (soda). Take your regular levodopa with a glass of this preparation instead of water. The carbonated water hastens disintegration of the tablet, and the acidity of both things helps in levodopa absorption. There are special tablets of levodopa (dispersible levodopa, Madopar) which can be dissolved in this preparation. Talk to your doctor about it.

Suffering From Parkinson's Disease - How You Can Maximise The Effect Of Levodopa? 

It has been proven by researchers that there is no definite cure for Parkinson s disease but its side effects and symptoms can be effectively managed. Medications are made available for treating the condition and ease the movement especially symptoms like stiffness and tremor. During the early stages of the disease, it is better to take the pill along with food to avoid nausea, which can be caused due to some medicines. However, in the later stages, the medication can be taken either 1 hour before a meal or 2 hours after a meal for effective treatment.

Symptoms of Parkinson s disease
Different therapies are used to treat Parkinson s disease and these include occupational, physical and speech therapy. The disease is known to manifest in many ways and some of the symptoms include sleep problems, fatigue, and constipation. The most common symptom patients suffer from is depression, and it is estimated that about 50% of the patients suffering from this disease experience depression. Commonly the symptoms of depression include worrying, feeling of sadness, and loss of interest. It has been found in some people that Parkinson s disease occurs due to abnormal genes. However, the real cause of the nerve cell break down is not known.

Important tips to consider

The best way to deal with the side effects of Parkinson s disease includes building a health care team, finding the best doctor, and managing your medications.
It is a progressive disease and in the initial stage, it starts with a mild tremor. However, with time it affects your speech and even your cognitive abilities. For that reason, it is important that the treatment plan is recognized and the symptoms that affect day to day life are managed properly.
The disease takes a toll on the emotional and mental health of a person and it is imperative to consult a licensed psychologist for that reason. Antidepressant medications are provided by doctors to treat this condition.
How to deal with Parkinson s disease?

It is very important for people suffering from Parkinson s disease to exercise and include a nutritious diet. The diet recommendation prescribed by the doctor should be followed and one should eat a low protein diet after consulting the doctor. The movements of the intestinal muscles are also affected with Parkinson s disease and these can result in constipation. Hence, it is better to include whole grains, vegetables, and fruits in the diet and eat foods that are rich in fiber.
It is very important that you drink lots of water so that the color of the urine is clear or light yellow. A fiber supplement like Metamucil or Citrucel can be taken every day, but the instructions provided on the label should be followed.

Parkinson's Disease - How To Handle The Side Effects?

One of the common ailments in the elderly people is the Parkinson s. A progressive disorder, when left untreated, results in worsening of the symptoms. Hence, it is essential to understand the treatment options available to manage the condition effectively. You may be suggested surgical therapies if medication is not effective enough to treat the symptoms.

Surgical treatment options can be beneficial for patients who are suffering from symptoms, but they do not help with treating the disease. In the past, surgical methods like Thalamotomy and Pallidotomy were used to destroy brain cells that contributed to the symptoms. While these methods are still used, they are very rare and situational.

Deep Brain Stimulation (DBS), an FDA-approved procedure, has become much more popular as it is much safer and does not involve invasive surgery. Instead of destroying brain cells like traditional methods, DBS involves sending electric pulses to the affected brain cells to reduce the symptoms. It is not a treatment procedure, but a means of bringing down the severity of Parkinson s to allow better and more comfortable treatment.

Deep Brain Simulation   Who are the right candidates?
Deep Brain Simulation is commonly used for Parkinson  s disease, but it is not recommended for everyone. It is a preferred method of treatment for people who have had Parkinson s for at least four years but have complications which include long periods of time where medications do not work, or symptoms return, uncontrolled and involuntary movements or the freezing/stiffness in the body.

Deep Brain Simulation is not recommended for those who have Dementia as it can lead to memory problems. The general rule of thumb that neurosurgeons follow is that Deep Brain Simulation can help with symptoms that do not get better with medication. DBS can help reduce medication requirements for patients as well as reduce the side effects that may occur due to medication.

Disorder specialists and neurosurgeons can conduct tests to determine if DBS is going to be effective for a patient before going ahead with such a procedure. An extensive assessment is necessary to understand the symptoms, the effect of Parkinson's drugs and also brain imaging is done. All of the expected benefits are then evaluated for the patients, and if the procedure can help alleviate the symptoms, DBS is given a green signal by neurosurgeons and patients can undergo the procedure.

How Does Deep Brain Simulation Work?
Deep Brain Simulation is a very complex procedure. Brain cells communicate with the rest of the body through electric signal, and these become irregular and do not work properly when affected by Parkinson's. DBS smoothens the functioning of these brain cells and reduces symptoms through electric pulses through the implantation of a medical device known as neurostimulator which is also referred as brain pacemaker.

But, as with any treatment procedure, DBS has potential risks and side effects, hence discuss with neurosurgeon thoroughly to access the suitability.

Adopting Deep Brain Stimulation For Parkinson's disease

Neurology is the branch of science and medicine dealing with the central and peripheral nervous system. The nervous system is made of the brain and spinal cord. The disorders, illness or injuries of the nervous system can become problematic for people suffering from them. One of the worst diseases of the nervous system is Parkinson s disease.

It is a progressive disorder affecting the central nervous system that leads to slowing down of movement and slurring of speech over a period of time. It is a condition where the nerve cells in the brain producing dopamine (a neurotransmitter) are affected.

Some of the early signs of Parkinson s include:

Tremor: If you have noticed a slight shaking of your hands or limbs, then Parkinson s might be the cause. The trembling can range from mild to severe as the disease progresses. The back-and-forth rubbing of your thumb and forefinger is known as pill-rolling tremor. One of the most prominent signs is your hand shaking even when it is rested.
Bradykinesia (slow movement): As the disease progresses, you may find it difficult to move your hands or legs or going from one place to another. Even making the smallest movement will require an increased effort on your part.
Rigid Muscles: The muscles in your body can become stiff causing you pain and making it difficult to perform physical activities.
Masked Face: Your face may experience spasms or become stiff periodically. It can also lead to complete paralysis on one side of the face.
Stooping or improper balance: Having Parkinson s disease can make your body posture imbalanced resulting in stooping or hunching over.
Decreased Automatic Movements: You may experience difficulty in smiling, blinking or swinging your arms while walking.
Alteration in voice or speaking: Your voice can become soft or you may slur while talking. You can also experience a monotonous voice.
Writing may become small: You can experience changes in your handwriting as it becomes small and crowded.
Loss of Smell: The smell of food sitting right in front of you may not register in your olfactory resulting in loss of appetite.
Constipation: Having Parkinson s disease can lead to patients experiencing irritable bowel syndrome.
Have Trouble Sleeping: It might be difficult to fall asleep for people suffering from Parkinson s. Also, there are sudden movements during the sleeping process.
Dizziness: People suffering from Parkinson s may faint from time to time.
These were some of the symptoms and signs by which you can tell whether a person has Parkinson s or not. However, as of now it is not curable and can only be treated with medicines. But, early detection can definitely help in preventing it from affecting the whole body.

Parkinson's Disease - Are You Aware Of These Signs?

Coping with Parkinson s disease is not an easy task. Whether you or your loved one is suffering from it, the effect of the disease takes a toll. Other than the fact that it is a degenerative disease and the neurological condition deteriorates over time, the mental trauma that Parkinson s brings; not only to the patient but to the caregiver as well, is a whole chapter on its own. When you are taking care of someone who is suffering from 

Parkinson s disease, it is natural that the emotional upheaval that you may go through will take a huge toll on your health and your mind. It is imperative that you prepare yourself thoroughly, whether you are the patient or the caregiver, about the disease and its treatments.

There is hardly any cure and treatment for the disease. It is still in its research stage and hence, often there is a strong sense of despair that sets in the mind of the patient and their loved ones. It is for this reason you have to prepare yourself to face and fight this disease. 

Here are some tips that may help you to cope with the treatments of Parkinson s disease:

Educate Yourself: Educate yourself about every detail of the disease, specific to the type of Parkinson s that has affected you or your loved one. Ask questions, whether to your doctor or the nurses. Search through the internet, you will get plenty of genuine information. This is necessary as it will prepare you to face the future head-on. You will understand what you are dealing with and how much worse it can get.
Stay Active: If you are the one who is suffering from Parkinson s, then write it down as the golden rule   I will have to stay physically active. Staying active will keep your muscles active and there will be a steady functioning of the nervous system. Staying active gives you the benefit of keeping the muscles at work, ultimately fighting the main symptom of Parkinson s disease. Being physically active is also essential to have a good mental health, both for the patient and the caregiver.
Connect With People: Talk to people, your friends, family members, children, grandchildren and anyone you feel like. If you have any estranged relative, it could be a good time to reconnect. Have wholesome conversations that will influence happy thoughts and encourage you to think and ponder on happy memories. This is crucial as Parkinson s invites depression and you will have to tackle it vehemently.
Talk to a Mental Health Professional: If you feel that you are losing a complete hold of your life and your depression seems uncontrollable, it is time to visit a professional psychiatrist and seek his/her advice in dealing with your troubled mental condition.

Impact Of Parkinson's Treatment - How Can It Be Managed?

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