Pancreas is a small organ that is located in the lower part of the stomach. It lies just behind the abdomen. It functions by producing the insulin hormone which is responsible for regulating blood sugar level in the body and breaking down food into glucagon which is stored in the body. This glucagon is converted into glucose which is used by the body for energy and other purposes. Therefore, pancreatic transplant is done in patients with a malfunctioning pancreas.

Why is pancreatic transplant required?
Patients suffering from type I diabetes usually undergo a pancreatic transplant. Type I diabetes is characterized by the inability of the pancreas to produce insulin, thereby leading to low blood sugar level. This type of diabetes occurs due to the malfunction of pancreatic beta cells whose primary role is to produce insulin. These beta cells make up around 65 to 80 percent of the cells found in the pancreatic islets. They typically malfunction when the body's immune system begins to attack and destroy the pancreatic beta cells. Therefore, type I diabetes is an autoimmune disorder. Patients with type I diabetes require insulin injections that might cause severe reactions. People dependent on insulin are prone to the development of diabetic retinopathy and diabetic nephropathy.

People with type II diabetes generally do not need pancreatic transplant because this type of diabetes occurs due to low production of insulin or lack of insulin resistance. Here is a list of the probable reasons why pancreatic transplant is required:

People who have type I diabetes but are not cured by standard treatment
Severe reactions to insulin injections
Low blood sugar
Kidney damage
Hypoglycemia unawareness
A pancreatic transplant can be of three types. They are:

Pancreas transplant only- People with type I diabetes and normally functioning kidneys require only a pancreatic transplant.
Pancreas and kidney transplant- Type I diabetes, in rare cases, leads to end-stage renal disease (ESRD) or end-stage kidney disease where one or both the kidneys are damaged. In such cases, pancreas and kidney are transplanted simultaneously to disable the dependence on insulin injection. This type of surgery may also be required when the pancreas and the kidneys come from the same donor.
Pancreas-after-kidney transplant- In some cases of type I diabetes, your doctor will recommend kidney transplant first followed by pancreatic transplant. It must be remembered that pancreatic transplant should be done by taking into consideration the side-effects caused by the anti-rejection injections administered after the procedure is performed. It may cause bone thinning, high cholesterol and high blood pressure in a patient s body. As the anti-rejection injections work by suppressing the immune system, the body s defense mechanism against infections and other diseases becomes ineffective to a considerable extent.
A pancreatic transplant is a serious procedure that requires a lot of deliberations and consultations with your doctor and should only be opted for when the benefits outweigh the side effects from the anti-rejection medications.

Pancreatic Transplant - When Is It Required?

Sometimes, when it comes to problems in the abdominal area, an ultrasound is not clear enough for a diagnosis. In such cases, an Endoscopic Retrograde Cholangiopancreatography (ERCP) may be performed. This procedure gives the doctor a clear view of the duodenum, bile duct, pancreatic ducts, gallbladder and papilla of Vater.

This procedure is usually performed under intravenous sedation without general anesthesia. This procedure involves the use of a duodenoscope, which can be described as a thin, long, flexible tube with a camera at one end. It also has a fiber optic bundle that transmits lights to the camera and a chip to transmit video images to a TV screen.

This is inserted through the patient s mouth and sent down the throat through the food pipe to the stomach and duodenum while the patient is lying on his or her back. The air pipe is left undisturbed so as to not interfere with the patient s breathing. Since the patient is not under general anesthesia, he or she can move and turn according to the doctor s needs. The papilla of Vater is a small nipple like structure with an opening to the bile duct and pancreatic duct. Once this has been identified, a small plastic catheter is passed through the duodenoscope into the bile duct or pancreatic duct through the papilla. Dye is then injected into the area and X-rays are taken of the bile ducts and pancreatic duct. In cases where a biopsy is needed, other instruments can also be passed through the endoscope. Plastic or metal stents can also be passed through this to relieve obstructions in the bile ducts and pancreatic ducts.

ERCP can be used to diagnose and treat a number of conditions in the liver, bile ducts, gall bladder, pancreas and papilla of Vater. These include:

  Blockage of the bile duct by gallstones, cancer, scars, tumors or compression from adjacent organs.

  Jaundice due to an obstructed bile duct. This can also cause light stools and dark urine.

  Persistent upper abdominal pain

  Unexplained weight loss and loss of appetite

  Diagnosing a Dysfunctioning Sphincter of Oddi within the Papilla of Vater

ERCP can also be used to confirm pancreatic cancer and cancer of the bile duct. Once the diagnosis is confirmed, the doctors can customize treatment according to the patient s needs.

Endoscopic Retrograde Cholangiopancreatography - Procedure and Results

Favorite of most Indian households, ghee is indeed a superfood. Apart from being widely used in Indian cooking, it has also been used as a remedy for cough and cold. Sadly, due to the misconceptions that surround the use of ghee, it is often underutilized. While some are worried that it may make them put on weight, others feel that it is bad for their heart. Little do they know that these misconceptions are not true, and ghee actually has limitless health benefits.

Let us read on to know more about the benefits that ghee has to offer:

Packed with nutrients: Many-a-times, people love the taste of ghee but have strike it off from the diet owing to popular belief that ghee is unhealthy and fattening. However, the opposite of it is actually true and the short-chain fatty acids found in ghee offer several health benefits and keep your gut healthy. Ghee obtained from grass-fed butter consists of fat-soluble vitamins A, D, E, K. Fats present in ghee are free of oxidized cholesterol, trans-fats and hydrogenated oils, thus, the fat present in pure ghee is healthy.
Great for immunity and bone strengthening: Including ghee in your daily breakfast not only boosts your physical and mental strength, but also ensures that your body stays fit and gains the potential to fight against several illnesses. Being a rich source of fat soluble vitamins, ghee supports in the growth and development of bones. It is also known to strengthen your muscles and tendons.
Lowers cholesterol: It is considered as an excellent option for people with high cholesterol levels. Since ghee contains Vitamin K2, it prevents plaque formation in the arteries, which in turn prevents the blockag that may obstruct blood flow and lead to complication. It also increases the level of good cholesterol and lowers the level of bad cholesterol in the blood.
Promotes weight loss: An excellent source of medium chain triglycerides (MCTs), is known to boost the metabolism which in turn promotes weight loss. It also improves digestion, makes you feel full and increases the oxidation of fat; all of which help in reducing weight.
How to differentiate if the ghee is pure or not?

Ghee is stocked in every Indian household, but the thought of whether it is pure or not often crosses our minds. Adulterated ghee may contain vegetable oils and other greasy elements which are bad for your heart and health. So, here are some methods that can help you check the purity of your ghee at home.

Pure ghee normally melts at body temperature. You can check it by putting a spoon of ghee on your palm if it melts then it is pure, if not, it is best to get rid of it.
Pure ghee melts within seconds and turns brown when heated. If the ghee takes longer to melt and appears light yellow in color, it is impure.

It has been established that ghee is indeed good for your health, but only if it is pure. The simple tests mentioned above can help you determine whether the ghee is pure or not. So, eat safe and stay healthy!

Ghee In Your Daily Diet - Did You Know It Has More Benefits Than You Can Think Of?

In this health-conscious era, more and more people want to stay fit. They constantly look for ways to maintain good health. Many have even developed a good habit of starting the day with a glass of lukewarm water as soon as they wake up in the morning. Yes, drinking water on an empty stomach offers the maximum health benefits. It not only stimulates the removal of toxins from the body but also benefits the overall digestive system. 

Although warm water isn t the most palatable, there are many reasons to start drinking it this way, either alone or with lemon. Below given are 6 reasons to start drinking lukewarm water on an empty stomach:

Digestive system: The food pipe, after having digested a variety of foods the previous day, would still be left with remnants. Starting the day with a glass of warm water acts as a good flush, which removes all these remnants. The warm or hot water also helps in removing greasiness, which is very helpful in people who eat a lot of junk food.
Helps in Weight loss: Drinking warm water on an empty stomach is perfect for those who are trying to lose weight as warm water raises body temperature and the metabolism. This, eventually, helps in burning more fat and boosting the weight loss efforts through diet and exercise changes. Ideally, you should add some drops of lemon in it. 
Strengthens Immune system: When a glass of hot water along with some lime is consumed early in the morning, it gives the required dose of vitamin C and potassium to the body, which strengthens your immunity system. Also, as the stomach is empty, the absorption is faster. 
Maintains body s pH balance: The body s pH turns alkaline as the ascorbic acid and the citric acid is easily digested and removed from the system. Drinking warm water helps in maintaining the required pH in the body.
Keeps you positive throughout the day: A nice juicy lime smells great, and this can be one of the best mood enhancers to begin your day with.
Skin and hair: For anybody with good skin, the key success factor is hydration, and a glass of warm water in the morning works like a cherry on the cake. When our body accumulates toxins, it becomes prone to illness and aging. A glass of hot water in the morning stimulates detoxification and helps in repairing skin cells and elasticity.
So, start your day with a glass of warm water and feel the difference. In case you have a concern or query you can always consult an expert & get answers to your questions!

Benefits of Drinking Lukewarm Water in Morning - Start Your Day With It?

The pancreas is a gland located in the abdominal region that performs two main functions for the body: produces digestive juices and the hormone insulin which regulates the blood sugar levels. The part which produces the digestive juices is exocrine and the insulin-producing part is the endocrine portion. Pancreatic cancer, which is an uncontrolled growth of the pancreas cells, often starts in the exocrine portion and is known as the pancreatic adenocarcinoma. The one which develops in the endocrine portion is known as neuroendocrine cancer or islet cell tumors.

Risk factors
Though not clearly established, the following factors are believed to up the risk of pancreatic cancer.

Smoking
Family history
Prolonged uncontrolled diabetes
Pancreatic conditions like inherited pancreatitis
Chronic inflammation of the pancreas
Symptoms
A pancreatic condition is of insidious onset, and the exact period of onset cannot be determined. The symptoms also are nonspecific abdominal symptoms, which do not pinpoint the pancreas per se.

Jaundice, which includes yellowing of the skin and whites of the white. This is because the growth of the pancreas puts pressure on the liver and bile ducts, and so hampers bile flow.
Weight loss, which was unintended. This is due to a bloated feeling plus inability to digest the foods.
Severe pain, which can be difficult and may even require regular injections to control.
Fluctuating sugar levels, which is unexplained.
Onset of diabetes, which is associated with weight loss and jaundice.
Increased tendency for blood clots.
Loss of appetite.
Bowel obstruction due to blockage of the growing pancreas.
Diagnosis
The above symptoms could lead to a further investigation that includes a few important tests, like the following.

Blood tests
Insulin levels
CT scan
Ultrasound
MRI
Laparoscopy, both to look for the extent of the disease and to do a biopsy, which can be used for confirming the type of cancer
Percutaneous transhepatic cholangiography: A dye is injected into the pancreas to study the spread of the dye, which will also help identify the diseased portion.
Treatment
Pancreatic cancer is very aggressive, usually not detected early, and has a very poor prognosis. So, if there is a family history or one has a prolonged pancreatic condition, it is advisable to go for annual screening to help with early detection and intervention. Once identified, treatment would include a combination of the three modalities   surgery, radiation, and chemotherapy. Surgery often may be followed by chemotherapy and/or radiation.

Prognosis
The prognosis for pancreatic cancer is very poor. Only about 25% of patients diagnosed with pancreatic cancer live past the first year. Early detection of risk factor remains the best way to improve prognosis. In case you have a concern or query you can always consult an expert & get answers to your questions!

Pancreatic Cancer - 8 Common Signs You Must Be Aware Of!

Enlarged pancreas can result beacuse of factors such as: 

An abscess in your pancreas: This refers to a dangerous formation inside the pancreas. Neglecting its occurrence can also turn out to be fatal. An abscess is a cavity containing pus that further infects the rest of the organ. Presence of harmful bacteria in the pancreas leads to such a case.
A cyst in the lining of your pancreas: Epithelial cysts in the pancreas can also cause the organ to swell up. Such cysts are mostly benign but they are accompanied by disabling pain.
Pancreatitis is one disease with an array of threats: Highly active enzymes within the organ can make its tissues wear down thus, affecting the size of your pancreas. If you are an alcoholic, you are more prone to develop this condition. It could also be contracted due to an excess of calcium or fats in the blood.
Cancer of the pancreas is dreadful too: Due to the unanticipated growth of cancer cells in the pancreas, the organ grows bigger. A person suffers from excruciating pain under the influence of this condition.
Pseudocysts in the pancreas can have serious ill effects: When benign cysts become unmanageably harmful, they result into pseudocysts. The cysts contain remains of your tissues and other damaging fluids that can increase the size of the pancreas.
An enlarged pancreas surfaces in the form of these symptoms:

The kind of stool you pass indicates a lot about your health. Oily poop can be indicative of an enlarged pancreas. Persisting diarrhea can also be a symptom of pancreatic ailments.
You may even experience an accelerated pulse rate.
You may feel feverish continually. Bouts of fever can impede your free movement and general health.
Health issues with your pancreas can make you suffer from jaundice. It could be a one- time affair or it could reappear from time to time.
Constant queasiness could hint at some underlying problem in your pancreas.
You may even lose more than a few pounds over a short span of time. Such a thing should not be taken lightly as it not only makes you look sick but also degrades your immunity.

Enlarged Pancreas - 5 Factors Behind It 

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