The liver is the largest internal organ in our body which performs multiple functions and it is the only gland that can regenerate quickly when it is healthy. The main role of the liver is to clean and filter blood coming via digestive tract previous to it flows to remaining body parts. Liver failure results in reduced ability of blood clotting, thereby causing severe problems in case of injuries. Apart from that, alcohol and viruses are also significant factors that stop the liver from functioning properly.

Liver Transplantation
Liver Transplantation enables even the people at the final stage of liver failure to lead longer and happier life. The success rate of Liver transplantation has increased drastically due to advanced surgical techniques. Liver transplant is the best option when the liver is damaged partially or entirely. It is a surgery that involves replacing a failed liver in a recipient with a healthy liver of a donor.

Who should go for it?
The main cause of liver failure in infants is Biliary Atresia. This occurs when bile ducts are absent or partially/fully blocked. Whereas in adults, liver disease is caused due to Cirrhosis - a condition in which liver is scarred and becomes dysfunctional in the worst case. Most common reasons for Cirrhosis are Hepatitis B and C, genetic disorders, alcohol consumption, toxic metals and obesity. One should immediately seek advice from a doctor when he/she suffers from following symptoms:

Fatigue
Nausea
Weakness
Weight loss
Jaundice
Fever
Abdominal Pain
Itchy Skin
Liver Transplantation Surgery
Two kinds of the liver transplant are available: 

Deceased donor transplant 
Living donor transplant
There are not enough deceased donor livers available to match all the liver transplant needs. Any living donor with a matching liver can donate a part of their organ to the person undergoing the liver transplant. As the liver can regenerate itself to its normal size in healthy people within a few months, there are no side effects of donating a part of the liver. A thorough physical and mental health examination will be performed for both the donor and the recipient to ensure that they can cope with the process and are aware of the risks involved. This includes psychological tests and blood tests. Patients are added to a waiting list as per their priority score. The score is assigned to a patient based on three blood samples creatinine, bilirubin and INR.

The priority score is termed as MELD (model of end-stage liver disease) in adults and PELD (pediatric end-stage liver disease) in children. The patient cannot undergo liver transplant if he/she has contracted cancer in any other part of the body or is suffering from heart disease or severe infections.

During the liver transplantation procedure, the surgeon removes some part of the liver from a donor and replaces damaged liver in the recipient with it. Both recipient's and donor's liver re-grow rapidly and reach normal size within months. As per statistics, recipients who receive the liver from living donor have a higher survival rate than those who receive it from deceased donors.

After surgery, both donor and recipient should maintain healthy and clutter-free life and follow strict diet rules and get vaccinated as per the chart provided by the doctor. They also need to avoid consumption of alcohol entirely and talk to a medical practitioner before taking any medications.

Liver Transplant Surgery - Who Should Go For It?

Iron deficiency anemia is a type of anemia, which occurs due to deficiency of iron. Iron is the main component of hemoglobin. So, a decrease in the hemoglobin level results in iron deficiency anemia.
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What are the Signs and Symptoms of Iron Deficiency Anemia?

Signs and symptoms appear when anemia is moderate to severe. In the mild stage, iron deficiency anemia often goes unnoticed. The signs and symptoms of iron deficiency anemia are:

Extreme fatigue (weakness)
Pale skin and brittle nails
Reduced  appetite
Headache, dizziness, or lightheadedness
Cold hands and feet with tingling numbness
Chest pain, palpitations, or shortness of breath
Inflammation or soreness of the tongue
Unusual cravings for indigestible substances, such as ice, dirt, or starch. 
What are the Causes of Iron Deficiency Anemia? 

Inadequate iron intake: Your body gets iron from the food you eat. If you consume too little iron, then your body may become iron deficient. Hence, resulting in anemia.
Inability to absorb iron: Iron is absorbed into your bloodstream from the food in your small intestine. In conditions like an intestinal disorder, this absorption of iron is hampered which results in iron deficiency anemia. Also, when your small intestine is bypassed or removed surgically, absorption of iron is hampered.
Blood loss: Red blood cells in your blood contain iron, and if the blood loss is severe, you can end up having iron deficiency. Conditions, such as bleeding hemorrhoids, colorectal cancer, and heavy menstruation can result in iron deficiency anemia.
Pregnancy and lactation: During pregnancy and lactation period, the iron requirement of the mother is more, and when it is unfulfilled, she may end up having iron deficiency anemia. 
Which Group is at Risk? 

Vegetarians
Women
Infants and children 
Frequent blood donors
How is it Diagnosed?

Diagnosis is made with the help of: 

Patient s history  
Blood tests, such as CBC and serum ferritin
Some additional tests, such as colonoscopy, endoscopy, and sonography to diagnose the underlying cause
Treatment

Treating the underlying cause is the primary step. 

Severe cases: When the iron level is too low, blood transfusion and even intravenous iron is given
Mild to Moderate Cases: Iron and vitamin C supplements are given in mild and moderate cases of iron deficiency anemia.
Can you Prevent Iron Deficiency Anemia?

Yes. You can prevent iron deficiency anemia by including iron-rich foods in your diet, such as:

Dark green leafy vegetables, such as spinach, peas, and beans
Dry fruits, such as raisins and apricots
Red meat, pork and poultry, and seafoodIron-fortified cereals, bread, and pasta
Include vitamin C-rich foods in your diet to enhance iron absorption. Vitamin C is found in Grapefruit, oranges, strawberries, lemons, and melonsLeafy greens, broccoli, peppers, and tomatoes

Iron Deficiency - What Are The Possible Signs And Symptoms?

Your skin is the largest and most sensitive organ of your body. Funguses that live in the human body especially armpits, groin area, nails, and feet, cause fungal skin infections. Weak immunity is the leading cause, with over 300 million people fighting fungal infections globally, every year.

Some of the common types of fungal skin infections are-

  Athlete s foot- Also known as Tenia pedis, Athlete s foot occurs when the tenia fungus begins to grow on your feet. It is most commonly associated with athletes because it grows in warm and moist climates such as in socks, near swimming pools and in locker rooms.

Symptoms of athlete s foot  

Infected area becomes soft and layers of skin begin to peel off
Redness, blisters, and cracking of skin
Treatment includes applying of topical antifungal ointments such as terbinafine while, severe cases may require oral medication.

  Ringworm   Ringworm is a highly contagious skin infection and is spread by person-to-person or pet to person contact. The fungus can also spread through infected towel, clothes, and mud.

Symptoms of Ringworm  

Red itchy patches on the skin which develop into raised ring like bumps
Formation of scales on the patches
Treatment of the infection includes medicines like miconazole.

  Jock  s itch- Also known as Tinea Cruris, these fungi thrive in moist and warm areas of the body such as the groin, inner thighs and buttocks.

Symptoms of Jock s itch  

Itchy red circular rashes over the body and burning
Chafing and peeling of the infected area
Treatment includes prescribed medication and maintaining personal hygiene.

Prevention is better than cure when it comes to fungal infections. Visit a doctor at the first signs of infection. A medical exam is the best way to detect the cause of a skin infection.

Fungal Infection Of Skin And Its Treatment!

Varicose veins are twisted, enlarged superficial veins that typically appear in the feet and legs.
For many people, the condition is simply a cosmetic concern while for others varicose veins include symptoms like swelling, discomfort and aching.

What Causes Varicose Veins?
Doctors believe that damaged or weak valves may cause varicose veins. Arteries carry oxygenated blood from your heart to other parts of the body and the veins send it back to your heart for recirculation. The veins of your lower body need to work against gravity in order to return the blood to your heart.
Muscle contractions in the extremities act as pumps while the elastic vein walls send blood back to the heart. Small valves open in your veins as blood flows to your heart, and then close again to prevent the blood from flowing back. If these valves become damaged or weak, blood may flow back and accumulate in the veins, causing it to twist or stretch.

Symptoms of Varicose Veins
You may experience the following signs if you have varicose veins  
  Discoloration of the veins   usually they appear blue or dark purple
  Legs feel heavy
  Itching around the affected veins
  Muscle cramps
  A throbbing, burning sensation
  Swelling and bruising
  Discomfort and pain the veins of the legs

The symptoms of varicose veins are quite prominent and require treatment. If the condition is not that severe, exercises and compression stockings may be prescribed to manage the symptoms. However, if you are looking for a long-term cure, laser treatment may be the best option for you.

Can Laser Treatment Cure Varicose Veins?
Your doctor may use highly focused laser beams to treat varicose veins. The laser emits heat, which forms scar tissues. The scar tissue closes the vein so it loses its source of blood and eventually dies. In a year or two, the vein is likely to disappear.

Here are the different types of laser treatment you can opt for  
  Simple Laser Treatment   The laser beams are focused on the outer surface of the skin. It helps cure the tiny veins that are located just beneath the skin. Normally, more than one session of laser treatment is required. Your doctor may schedule you for a session every 6-12 weeks.

  Endovenous Laser Treatment   This type of laser treatment is directed towards treating larger varicose veins that appear in the legs. The doctor passes a laser fiber through a catheter (a long, thin tube) into the veins. While doing this, he/she keeps a close watch on the veins through a duplex ultrasound screen.

Laser treatment is less painful than other procedures like vein stripping and ligation. The entire procedure can be done while you are on local anesthesia or sedatives. Moreover, the time for recovery is relatively short. You can expect to get back to your routine activities in a week or two following laser treatment.

Laser Treatment For Varicose Vein!

The bones and joints orchestrate very well with each other for smooth movements of various joints and the spine. However, due to various reasons, some identified and others unknown, there could be inflammation of the areas where the bones join the muscles leading to impaired movement. The range of motion could be reduced or it could be painful, thereby, limiting movement. Spondyloarthritis includes a group of inflammatory diseases that involves the bones and joints and enthuses which are areas where the ligaments and tendons attach to the bones. This causes conditions like plantar fasciitis, ankylosing spondylitis, psoriatic arthritis and reactive arthritis. The term spondyloarthritis is a blanket term to describe any of the above-mentioned conditions.

Read on to know a little more in detail about it:

Causes: While the exact etiology is not identified for sure, most patients with spondyloarthritis have an autosomal dominant gene (HLA-B27). Chronic infections could trigger the onset of the disease too.

Symptoms:

1. In all forms of spondyloarthritis, there is always inflammation of the spine, joints and entheses. If the fingers or toes are involved, there could be swelling leading to what are typically known as 'sausage digits'.

2. There is sacroiliitis which is inflammation of the joint between the pelvis and the spine, and spondylitis which is inflammation of the joints between the spines. 3. Family history and autosomal dominant gene.

Diagnosis:

A detailed medical history and physical examination form the cornerstone of a confirmed diagnosis. In addition, radiographic examination and diagnostic blood tests also could be done to confirm the diagnosis. Radiographs, especially, of the spine and the low back show typical changes including sacroilitis in suspected cases of spondyloarthritis. If the spine does not show these changes, but there is a high likelihood of spondyloarthritis, then MRI (magnetic resonance imaging) can be used to confirm the diagnosis.

As a final step, a blood test for the HLA-B27 gene can also be confirmatory. However, it is not true that a person with the gene will definitely develop the disease.

Treatment:

The most important aspect of treatment is the use of pain medications and anti-inflammatory drugs (NSAIDs) which help manage pain and inflammation.
Corticosteroid injections may sometimes be given directly into the joint spaces or the membranes to provide quick relief of these symptoms.
ESWT / RSWT has a definite role to cure enthesopathy. Plantar fasciitis, and achillodynia can be cured with ESWT. Even small joints of hand and feet are amenable to treatment with RSWT. It is nonoperative and noninvasive treatment and has no side effects.
Very rarely, stronger drugs such as methotrexate or sulfasalazine may be used.
Another set of drugs known as TNF-blockers (tumor necrotizing factor blockers) are also shown to be highly effective in controlling the pain of the spine and joints.
In very severe cases, surgery may be required to correct joint damages or correct severe degenerative changes.
Exercise plays a very vital role in controlling the issue and improving range of motion.

What You Should Know About Spondyloarthritis?

When particular nerve cells in the brain don't function properly, it leads to epilepsy, which is a common brain disorder. There are several variants of epilepsy, and the one that you are suffering from would play a major role in the type of seizure you are likely to have. Here are the two most common type of seizures:

Common types of Seizures

Generalized seizures: This type of seizures take place when nerve cells on both sides of the brain start misfiring. They may lead to black out, fall or muscle spasms.
Focal seizures: It starts in a particular area of the brain, and the names of the seizure are based on the affected area of the brain. They may lead to both emotional and physical effects which may affect the way a person feels or sees or hear things that have no real presence. In particular cases, the symptoms of focal seizures are regarded of some other kinds of mental or nervous disorder.
Seizures are not considered an either-or thing since some people tend to have a particular type of seizure which gradually alters its course. It is not always easy to classify certain types of seizures which are called unknown-onset seizures and may lead to both physical and sensory symptoms. Both focal and generalized seizures can be categorized into various groups. The most common are listed below:

Subcategories of focal and generalized seizures

Simple focal seizures: It may change how the senses read the surroundings of a person. It can make a familiar taste or smell appear strange. Some people feel dizzy or visualize flashes of light or make the affected individual feel nauseated or sweaty.
Complex focal seizures: It normally happens when a part of the brain which controls emotion and memory gets affected. The affected person may feel awake even when he has lost consciousness. It can take several minutes for a person to come out of the problem.
Secondary generalized seizures: It starts when a part of the brain spreads to the nerve cells. They may lead to a few physical symptoms including muscle slackness and convulsions.
On the other hand, there are six variants of generalized seizures:

Clinic seizure: The muscles tend to have spasms which make a face, neck, and arms jerk rhythmically. It can last for minutes together.
Tonic-clonic seizure: These are the most notable type of seizures and leads to stiffening of the body, jerking and shaking along with the loss of consciousness. It can last between 1 to 3 minutes, and in case they go for a longer span, it is important to seek immediate medical attention. It may lead to breathing issues and may cause the person to bite his tongue or cheek.
Tonic seizures: When the muscled in the legs or arms or trunk tense up for more than 20 seconds, it is called a tonic seizure. If the affected person is in standing position, he or she may end up falling.
Other types of generalized seizure include atonic seizure, absence seizure and myoclonic seizure which are commonly seen in people who have epilepsy.

Seizures - Know The Common Types!

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