Egg Freezing, which is also known as mature oocyte cryopreservation, refers to the method through which reproductive potential is restored among women. Eggs get harvested from the ovaries, frozen and in an unfertilized manner and are stored for purpose of using them later on. The egg freezing procedure is recommended for those women, who would like to delay conceiving baby due to various kinds of reasons.

Before the freezing of eggs, it is important to first retrieve the eggs. Let us look at how the eggs are retrieved, followed by the procedure of egg freezing through two different ways.

Retrieval of Egg

Egg Retrieval takes place just like it is done in case of in vitro fertilization (IVF). Women would need to be put under medication for hormones or through injections, which shall lead to the stimulation of ovaries, leading to more eggs getting matured. After this women would receive the necessary medication to stimulate ovulation and then the extraction of eggs takes place through the use of a needle. Specialists perform this whole procedure by putting women under the effect of anesthesia and are also guided by ultrasounds. Once the extraction is completed, the freezing takes place.

There are two different techniques involved in the egg freezing process. They include:

Slow Egg Freezing Method

A substance called cryoprotectant is used in order to protect the biological tissues from getting damaged out of freezing. This slow freezing method of getting eggs freezed relies on low initial concentrations of crytoprotectant. The cryoprotectant in low concentration is introduced when the egg is at a relatively warm temperature and still continues to experience the usual functions of a living cell. Then the cryptoprotectant would spread all throughtout thus fill the egg, hence replacing most of the water inside the egg. The egg is then inserted into a small container made of plastic and ultimately get placed inside a cooling chamber. The lowering of temperature, to around -6 degree centigrade, takes place through injecting very tiny amounts of liquid nitrogen into the cooling chamber. The cooling process is controlled by a computer.

The main purpose of these techniques is to avoid ice crystals from getting formed in the egg. During the spreading of the cryoprotectant, if the ice crystals are still present, they can cause damage to the egg and hence the egg may not survive the process of thawing. Then the temperature is lowered further to around -32 degree centigrade. By this time, the egg s metabolic rate become slow. The container where the egg was placed, is then dipped inside the liquid nitrogen, forming a solid.

Rapid Egg Freezing Method or Vitrification

At the time of rapid freezing method, there is high concentration of initial cryoprotectant whereas the cell remains at room temperature. The egg is unable to stay for long in this temperature and thus gets poured immediately onto the liquid nitrogen. Cryoprotectant spreads at a rapid rate so as to avoid ice-crystal from getting damaged. Vitrification is a very new method for freeing eggs. Recent research has shown that vitrification of eggs largely improves the possibility for survival after thawing and the rates of pregnancy.

Different Techniques That Can Be Used For Egg Freezing!

Factors that determine the success of your IVF procedure

IVF or In Vitro Fertilization is a process wherein an egg is fertilized by a sperm in a laboratory dish to form the embryo (baby's first cell) which after growth in artificial medium in the lab is transferred into the uterus of women, In general, a blood sample is collected to determine whether you're pregnant or not about 10-14 days after the eggs are retrieved.

Coming to the success of the procedure, a number of factors are at play and these are:

The age at which you get pregnant

A factor that plays a role in influencing your chances of experiencing success in your IVF procedure is the age at which you opt for this procedure. The lower your age, the chances that you may get pregnant and deliver a healthy child using your own eggs witness an increase. On the other hand, if you're aged 41 and above, or your egg reserve is very low donor eggs are the most preferred option as they help to increase your prospects of meeting a success.

Lifestyle habits

Certain lifestyle factors can significantly affect your prospects of getting pregnant through this route. Smoking can reduce your prospect of success using this procedure by about 50%. It can cause you to have lesser number of eggs retrieved during the procedure while increasing instances of miscarriages. Likewise, obesity, alcohol use, consumption of excessive caffeine and drugs can adversely affect your chances of getting pregnant using IVF.

Cause of Infertility

If your supply of eggs is normal, success rate using IVF is high. Women who suffer from the problem of endometriosis experience lesser chances of getting pregnant than women who have unexplained fertility.

Reproductive history

IVF success rate chances are higher if you've delivered a baby previously using IVF.

Embryo status

Embryos that are better developed with good grade stand a higher chance of experiencing success than less developed embryos. More importantly, not every embryo is able to survive the development process.



What are the factors that determine the success of your IVF procedure?

IVF is a useful process for people who want to become parents but have exhausted all other means of being so. However, the in-vitro fertilization method is definitely not suitable for everyone. Here are some facts you need to know about the procedure and they will help you determine whether you are suited for the program or not.

1. IVF Takes Time
Even though most clinics may not tell you this, but the IVF procedure takes a bit of time to deliver the desired results. On an average, the treatment can take anywhere between four weeks to a couple of months to produce results, depending on the patient s ability to respond to the medicines used. The procedure involves artificially stopping the menstrual cycle of the woman. Next, the ovulation process is stimulated so that the healthy egg can be extracted from the womb. The eggs chosen are then fertilized and left to undergo embryo culture for another six days. After this, the eggs are implanted back into the mother s body.

2. The process Can Be Stressful
IVF treatment and pregnancy can be quite a stressful period of time for the parents in question. The mother needs to be constantly monitored to check for any abnormal response to the pregnancy. Regular checkups by the doctor along with blood tests may also be suggested. However, this stress has very little chance of affecting the quality of the pregnancy. So, do not worry that overstressing yourself will lead to complications for the embryo.

3. More Than One Cycle Needed For Pregnancy
IVF treatment occurs in cycles. Each cycle involves transplanting a fertilized egg into the womb. However, pregnancy, right after completion of the first cycle, is quite rare. In fact, almost all patients need to undergo several similar cycles in order to get pregnant. So, do not be disheartened if you do not get pregnant after undergoing the very first cycle of IVF treatment.

4. IVF Is Costly
Not everyone is able to afford the high cost of IVF. Others may be able to afford the cost of undergoing a couple of cycles of the same, after which the high costs can become a burden. Only a select few can bear to carry on with the treatment until the pregnancy arises. So, consider your financial condition prior to signing on for such a treatment option.

At any rate, consult with an expert to get an even better idea about the IVF procedure and the consequent pregnancy. 

All You Need To Know About The IVF Procedure!

Contraceptives are generally drugs and devices, which are used to prevent pregnancy. A large number of contraceptives are available which allow the couple to enjoy sex without running the risk of unwanted pregnancies. The general categories of contraceptives are explained below:

Barrier Methods:
i. Male Condom: It is one of the most common forms of contraception. They are worn on the penis before sex is initiated. For safety purpose, a new condom should be used every time the person has sex.

ii. Female Condom: Much like male condoms, these are available at over-the-counter pharmacies without prescription. The condoms can be inserted to the vagina anytime within a period of 8 hours prior to sex.

iii. Diaphragm: This should be coated with a spermicide before sex and placed inside a woman's vagina so that the sperms are prevented from entering the uterus.

iv. Cervical Cap: These are used as replacements for diaphragms because some women may develop bladder infections such as cystitis while using it and these caps have lesser contact with the vagina.

Hormonal Methods:
The main implementation of hormonal changes to provide contraception is the pill. This is the most common form of female contraception available. It comes in two forms:
i. Combined contraceptive pill: Contains a combination of hormones such as progestin and oestrogen.
ii. Mini-pill: Contains only progestin: It is available only with the prescription of the doctor and should be used as per the prescription.

Intrauterine Devices
The intrauterine device (IUD) is a long-acting and reversible form of contraception for women. It is of two types: Copper IUD (contains copper) and Hormone-releasing IUDs (progestin hormone is released into the womb slowly). It is a small device that is fitted inside the womb and it provides contraception by facilitating the prevention of fertilization of the egg.

Sterilization
This is a lifelong option that is available for both men and women. In males, the procedure is known as vasectomy which basically ties and cuts off the tubes that carry the sperm.

In women, two forms of sterilization are available; surgical and non-surgical. Surgically, the fallopian tubes are cut and tied using small cuts in the belly so that the ovaries and uterus are not linked. Non-surgically, coils are inserted into the fallopian tubes so the resultant development of scars leads to complete blockage of the tubes.

Other forms of contraceptives include contraceptive patches, vaginal rings, contraceptive injections, spermicides and contraceptive implants.

Different Types of Contraceptives and Its Uses

Use of contraceptives is really important to avoid unwanted pregnancy. Countries like China and India, facing the problem of population explosion lay more stress on the use of contraceptives. However, you must always use or take oral and barrier contraceptives following the advice of a medical practitioner unless it is absolutely necessary to go ahead without consultation. The reason behind medical assistance is your own health. Contraceptive methods do have a vast range of side effects that can result in health hazards. There are various kinds of contraceptives; each having its own set of advantages and disadvantages. Being acquainted with the side effects of some contraceptive methods can help you choose wisely in times of need.

Possible side-effects of using condoms: Some men are allergic to latex. Using condoms can lead to heightened sensitivity. It can also lead to rashes in your genitals. Condoms are not foolproof. They do not provide total protection against sexually transmitted infections, HPV or against Syphilis and Herpes. These diseases can be contracted by coming in contact with genital skin that is not covered by a condom.
Possible side-effects of a Contraceptive Film: A contraceptive film might act as an interruption in your sexual activities if it is not placed properly, that is to say it must come in contact with the cervix to be effective. Using the film nonoxynol- very frequently can make you susceptible to life threatening diseases like HIV and other STIs.
Possible side-effects of a Cervical Cap: A cervical cap has to be inserted by a clinician and requires immense care to be fitted in later. Some of its side - effects can be of serious concern. If it is left inside for more than forty eight hours, it can result in toxic shock syndrome. Toxic shock syndrome is an infection that mars your overall health. It is also known to increase the chances of inflammation of the surface of your cervix.
Possible side-effects of Progestin only pills: Progestin only pills or mini pills can subject you to long- lasting depression. It can make you feel bloated and can actually increase your weight to a great extent if used on a regular basis. Minipills lead to irregularities in your menstrual cycle and might also make bleeding during menstruation scanty.
Possible side-effects of combined oral contraceptives: If this is your first month on combined oral contraceptives, you might feel nauseous and they can give you a terrible headache. Women taking these pills have a higher chance of developing cervical dysplasia. If you wish to discuss about any specific problem, you can consult a gynaecologist and ask a free question.

Side Effects of Different Contraceptive Methods

What are the latest advancements in male contraceptions?

The drawback of surgical approaches (such as vasectomy), especially patient compliance and the low success rates with condoms has spurred research on hormonal contraceptive dosage forms. There is a dearth of investigations in the development of pharmaceutical preparations. Evolving technology in the 21st century as well as improvement in living standards further underline the need for new male contraception approaches, especially those that entail new drug delivery methods.

Here are few areas where male contraception is being researched and used in some countries

Hormonal contraception for men is possible, and we are at the threshold of an important breakthrough. Combined testosterone plus progestin administration is more effective and safer than testosterone alone. Combination of testosterone plus an anti-androgenic progestin has several advantages over other formulations. In combined therapy, single injection formulation may have better compliance. 

Conventional male contraception 
Abstinence (doesn't work well)
Masturbation
Male condom
Vasectomy
There are other methods being developed but not sure they are there yet. But for guys? Their options are stuck in a time warp. If a man wants to take pregnancy prevention into his own hands, his choice basically comes down to condoms, a vasectomy, withdrawal, or abstinence. That s why it's so amazing that scientists are finally developing some real advancements when it comes to male contraception.

Researchers writing in the April issue of the Open Access Journal Contraception published a rundown of the top emerging options. A few hold real promise, particularly a daily or weekly pill that would deliver a dose of artificial hormones to a guy s bloodstream, which would then act on reproductive hormones to stop sperm from being produced. Like the female hormonal pill, the male hormonal pill would be reversible. But also like the female hormonal pill, there appear to be side effects, among them acne, weight gain, and even trickier to work around, changes in testosterone levels that trigger a plunge in libido.

Non-hormonal techniques are also being developed, particularly a vaccine that immunizes men with antibodies to halt sperm production. This so-called male birth-control shot is encouraging, because it targets sperm directly (rather than targeting other hormones in the body) and doesn t have the testosterone-lowering side effects of a hormonal pill. Each injection would last for long intervals (experts aren t yet sure how long), but the pregnancy-preventing effects would be reversible, if and when a guy decides he s ready to be a dad.

So when can you expect to see men rushing out to the pharmacy counter to pick up their new birth control Rx?  I think we may see a novel male contraceptive within 10-12 years, That may seem far off, but hey at least it s finally within sight.

Male Contraception - An Insight!

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