Obesity is the new-age lifestyle disease with multiple ramifications. While its effects on the physical aspects are very evident, the damage it does to the brain are more severe, though not obvious. Read on to know some harmful effects of obesity on the emotional well-being.

Leads to binge eating: There is a certain pleasure in eating sugary and fatty food, and this is lost with depression. Therefore, to get that emotional satisfaction, people tend to eat more chocolates, cookies, milkshakes, and other weight-accumulating food items, which further add to obesity. Greater the weight gained by a person, lesser the response or happiness from such food products.
Increases impulsivity: The area of the brain known as orbitofrontal cortex, which is in charge of controlling impulsivity, shrinks in obese people. This results in people eating more impulsively.
Affects immunity: Obesity is a major cause of inflammation, leading to damage in certain parts of the brain. This impairs the immune system, making the affected person more prone to infections and tissue damage. This leads to increased chances of diabetes, heart disease, stroke, sleeping disorders, eating disorders, etc. The chemical known as C-reactive protein increases as seen on MRIs in obese people, and which is usually seen in patients with chronically increased inflammation.
Effects on memory: As the BMI increases, there is a decrease in scores of memory tests. This effect is more obvious in women after menopause. With increased fat accumulation, more hormones are released, which affects the memory. Increased inflammation also affects cognition and memory.
Increased risk of dementia: With more belly fat accumulating, there is extra stress on the body to burn the visceral fat. This reduces brain size and causes certain hormones to release, which further affects the body s ability to remember things. It has been proven that people with smaller brain size are at greater risk for developing dementia.
Weight loss stress adding to more stress: When obesity sets in and the BMI goes up, there is an added pressure to lose weight, which further ups the stress levels. During these dieting days, the brain is constantly alert and finds ways to eat more. This also leads to excess eating. Moreover, there are indications that there could be genetic changes during this phase, which may leave a permanent mark in the person s composition.
Depression: When a person is not happy with their reflection in the mirror, the chances of feeling good and happy are very less. In this age, where aesthetics plays a major morale booster, an obese image staring back does not help at all.
So, if you have a risk of obesity, watch out. It is not just how you look, but how you feel is also altered.

Obesity - How It Affects The Human Brain?

Migraine is a severe form of headache wherein, the excruciating pain is accompanied by an extreme sensitivity to sound and light; you also experience nausea. The headaches usually affect either side of the head and are throbbing in nature. Hot flashes, numbness of limbs and blind spots in the eye; these are often considered as warnings. In certain cases, migraines can cause blackouts that can range from a few seconds to a few minutes.

Migraine occurs in four stages:

Pro-drome (symptom indicative of an onset of an illness)
Aura (visual auras including blurred vision)
Headache
Post-drome (the residual effects of migraine characterized by fatigue and lethargy)
But the occurrence of these stages varies across individuals. The causes of migraines aren t specifically understood. It may be due to the interaction of the brain stem with the trigeminal nerve, which is an important pain pathway of the brain. Imbalances in hormonal levels or in the levels of neurotransmitters such as serotonin may also prove to be a causal factor.

Symptoms

Migraine may be triggered due to stress, physical exertion, and excess intake of alcohol or food additives such as MSG (Monosodium Glutamate). Changes in the environment and sleeping patterns may also be probable culprits.

Migraine can be easily distinguished from regular headaches, given the fact that migraines last longer and are rather severe in nature with pain felt in one part of the head. Most people experience the  Aura stage where they have visual flashes right before headache. Nausea, eye pain or sensitivity to light and sound are other factors helpful in distinguishing migraine from other headaches.

Symptoms can occur a while before headache, immediately before headache, during headache and after headache. Although not all migraines are the same.

Typical symptoms include:

Moderate to severe pain, usually confined to one side of the head during an attack, but can occur on either side of the head
The pain is usually a severe, throbbing, pulsing pain
Increasing pain during physical activity
Inability to perform regular activities due to pain
Feeling sick and physically being sick
Increased sensitivity to light and sound, relieved by lying quietly in a darkened room
Some people experience other symptoms such as sweating, temperature changes, tummy ache and diarrhea.
Complications in migraine may include:

Chronic migraine which last up to 15 days or more
Status Migrainosus where the attacks last for over 3 days
Migrainous infarction where the aura lasts longer than it should, cutting blood supply to the brain. 
If you wish to discuss about any specific problem, you can consult a neurologist.

Migraine - Know The Causes and Symptoms!

Brain cancer is a disease of the brain in which cancer cells (malignant cells) arise in the brain tissue. Cancer cells grow to form a mass of cancer tissue (tumor) that interferes with brain functions such as muscle control, sensation, memory, and other normal body functions. Tumors composed of cancer cells are called malignant tumors, and those composed of mainly non-cancerous cells are called benign tumors. Cancer cells that develop from brain tissue are called primary brain tumors while tumors that spread from other body sites to the brain are termed metastatic or secondary brain tumors.

Prologue:

Brain cancer is actually the abnormal growth and uncontrolled growth of the cancer cells in the brain,that forms a tumor in the brain.Tumours can be either benign or malignant.

Benign brain tumours are abnormal collections of cells that reproduce slowly and usually remain separate from the surrounding normal brain.

Malignant tumours reproduce and grow quickly. Their borders are hard to distinguish from the normal brain around them.

Symptoms:

There are few early symptoms of brain cancer, but as the tumour grows within the confines of the skull, it causes increased intracranial pressure and exerts pressure on the brain, causing signs to develop.

Brain cancer symptoms and signs are varied and depend on the area of the brain involved, but can include:

Headaches.

Seizures.

Nausea and vomiting, which, CANSA reports, may be worse in the morning or after a sudden position change.

Difficulty walking or clumsiness.

Vision changes.

Changes in alertness.

Behavioural impairment.

Causes:

Brain cancer occurs when there is an uncontrolled growth of cancer cells in the brain that form a malignant brain tumor. The underlying cause of primary brain cancer, cancer that begins in the brain, is not known. Secondary brain cancer is caused by a cancer of another organ in the body, such as the breast, prostate, kidney, skin, or bone, that has spread to the brain.

What are the risk factors for brain cancer?

Certain inherited conditions, including neurofibromatosis, Von Hippel-Lindau syndrome, Li-Fraumeni syndrome, and Turcot syndrome

Personal history of cancer or family history of brain cancer

Impaired immune system

Radiation therapy of the head

Treatments Options:

Treatment

Surgery is the main form of treatment for brain tumors that lie within the membranes covering the brain or in parts of the brain that can be removed without damaging critical neurological functions. The goal is to remove the entire tumor, whenever possible, as a tumor may recur if any tumor cells are left behind. Radiation therapy and chemotherapy are generally used as secondary treatment for tumors that cannot be cured through surgery alone.

Stereotactic radiosurgery

Stereotactic radiosurgery is a treatment option that delivers a high concentration of radiation directly to the tumor in order to stop its growth, while delivering only a minimal dose of radiation to the surrounding tissue. Unlike conventional surgery, stereotactic radiosurgery does not require making an incision to remove the tumor. It can be especially effective in patients with many small metastatic brain tumors.

Brain Cancer

Cranial nerve palsy is one of the common culprits of causing double vision. This is all the more true for people above the age of 60. A person is more prone to cranial nerve palsy if he is suffering from high blood pressure and diabetes. This is the reason why this disease is more commonly known as diabetes palsy. Eventually, though they get better and the problem of double vision disappears.

Symptoms:

One weak cranial nerve leads to the weakness of other cranial nerves as well. In case the eyes fail to move together, chances are that the patient will have double or blurred vision. In case the sixth nerve gets affected, side to side double vision is encountered. For the 3rd and 4th nerve disturbance, there could be a vertical double vision. The lack of blood flow causes pain to the eye.

Possible Causes of Cranial Nerve Palsy?

Cranial nerve palsy can result from traumatic or congenital factors. They can also result from vascular diseases such as strokes, hypertension, diabetes, and aneurysms. It can also arise out of infections, increased intracranial pressure, migraines, and tumours. A patient's age and clinical findings help a doctor decide the right course of treatment.

Treatment:

There are no particular treatments which can speed up the recovery of cranial nerve palsy. In a case of pupil pain, doctors may prescribe anti-inflammatory drugs such as Motrin and Advil. They key to natural recovery is to ensure that the blood sugar and the blood pressure is diligently controlled. By patching the eyes, the problem of double vision can be resolved. They are typically worn over both the eyes. They are however known to slow down the process of recovery and strain the eye. There is no known exercise to fix this condition. Botulinum injections are sometimes used by doctors to straighten the eyes but the result of such a treatment greatly varies from person to person. Doctors mostly rely on watchful waiting until the phase passes within 6-8 weeks. Pain medications are recommended on a case to case basis.

Lifestyle Changes:

Managing cranial nerve palsy can be difficult for a working person. It involves many lifestyle changes till the condition fully cares. Some of the suggestions given by an ophthalmologist include resting the eye as long as one can. Reading or working on a computer should be eschewed since it puts great pressure on the eyes. The eye should not be contacted with forehands in case there is too much pain. Other basic hygiene issues include taking the medicine time to time, cleaning the eye with fresh water two to three times a day, putting the eye drops on time as prescribed by the doctor.

How To Treat And Manage Cranial Nerve Palsy?

Migraine vs. Headache: know the difference

How to differentiate between a migraine and headache?

When you feel pain or pressure in your head, it may become difficult for you to assess whether you are experiencing a common headache or a migraine. Let's understand how different they are from each other.

A typical headache usually affects both sides of your head and varies from a mild to moderate pain. It can last from 30 minutes to up to a period of one week.

Some specific areas which get affected by a headache are:

  temples

  forehead

  back of your neck

Factors that trigger this headache type are a muscle strain, stress or anxiety. 

A migraine, on the other hand, is also a type of a headache which results in an acute throbbing sensation in one part of your head. Usually, migraine headaches are highly painful. Migraine pain makes it difficult for a person to carry out his/her daily tasks. Symptoms or signs associated with migraine attacks are:

  vomiting

  nausea 

  sensitivity to sound or light

  pain in the temples

  temporary loss of vision

  pain behind your ear or eye

What are the common causes of a migraine?

  hormonal imbalances in women - fluctuations in oestrogen, especially during menopause or pregnancy seem to trigger a migraine

  drinks like wine and extremely caffeinated beverages 

  foods such as salty foods, aged cheese as well as processed foods can trigger the migraine attack.

  medications - vasodilators such as nitroglycerine and oral contraceptives can intensify migraine pain.

How to treat a headache?

Fortunately, you can get rid of stress-induced headaches through over-the-counter treatments, which include:

  aspirin

  acetaminophen

  ibuprofen

How to treat a migraine?

If you experience migraine attacks less frequently, these medicines may give you quick relief:

  triptans, such as rizatriptan (Maxalt) or almotriptan (Axert)

  antinausea medicines, such as chlorpromazine (Thorazine), promethazine (Phenergan) or prochlorperazine (Compazine)

  non-steroidal anti-inflammatory drugs (NSAIDs), such as acetaminophen, naproxen sodium, aspirin or ibuprofen

Some preventive tips:

  make changes in your diet such as avoid such foods, including caffeine and alcohol which are believed to trigger headaches.

  you can also try muscle relaxation exercises, yoga or meditation to ease the migraine attack. 

If you would like to consult with me privately, please click on 'consult'.
Related Tip: 8 Common Migraine Triggers You Must Stay Away From

Migraine Vs. Headache: Know the Difference

The primary aim of the treatment in patients suffering from seizure is leasing a seizure-free life without giving way to any adverse effects. This goal can be accomplished in over 60 percent people with the help of anticonvulsants. Some patients also experience adverse effects since they suffer from a seizure which is refractory to medical therapy. Here are some of the common treatment options for seizures:

Monotherapy: Sometimes, monotherapy is given as it reduces the chance of all sorts of adverse effects and even avoids drug interactions. Moreover, this type of treatment approach is much less expensive than polytherapy since many older generation of the anticonvulsant agent comprises of hepatic enzyme which is responsible for reducing the serum level of the concomitant drug which leads to an increase in the dosage level of such medicines.
Social And vocational rehabilitation: People suffering from problems in psychosocial adjustments after the diagnosis may also need social and vocational rehabilitation. Many physicians do not pay enough attention to the consequences that an epilepsy diagnosis may leave on the patient. For instance, people with epilepsy may have a fear of experiencing next attack of seizure and they may be unable to work at heights or drive.
Consulting an expert: It is important to refer patients with intractable spells to epileptologist or neurologist for subsequent workup. A neurosurgical consultation may also be needed when the patient has to be treated surgically.
Importance Of anticonvulsant therapy
Patients who have had already suffered from recurrent attacks of unprovoked seizure may need treatment with an anticonvulsant. This treatment is not recommended until the person has risk factors for suffering from the problem yet again. The primary means of treating seizure is anticonvulsant therapy where the most suitable drug is chosen based on accurate diagnosis of the syndrome as a response to specific anticonvulsants may vary from one patient to another. The difference in response may reflect the various pathophysiologic mechanisms in different types of seizures.

Types of anticonvulsant therapy
Some of the anticonvulsant therapy medication may have multiple action mechanism while some have an only single mechanism of action. Some of the most common variants of the therapy include:

Neuronal potassium channel referred to as KCNQ opener
Blockers of unique binding sites such as perampanel, gabapentin, and levetiracetam
H-current modulators such as lamotrigine and gabapentin
Carbonic anhydrase inhibitors such as zonisamide and topiramate
Alpha-amino 3-hydroxy 5-methyl 4-isoxazole propionic acid receptor blockers like topiramate and perampanel.
N and L-calcium channel blockers like zonisamide, valproate, topiramate, and lamotrigine
Even though there are so many types of drugs available, all of them cannot be used for the treatment of seizures. Doctors would evaluate the condition thoroughly before prescribing a medication that can be helpful in reducing the severity of the condition.

Seizures - 3 Ways It Can Be Treated!

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