Autoimmune disorders are one of the least understood disorders in the whole of medical science. Systemic Sclerosis is also an autoimmune disorder in which the skin undergoes changes in texture and characteristics. 

However, the changes are not confined to the skin alone. It can affect blood vessels, muscles, digestive system, heart, kidneys, as well as the lungs. It typically affects people in the age group of 30 to 50 years, but the good thing is that doctors can diagnose this at any age. 

It has been observed that more women fall prey to this disorder than men. The severity of symptoms may also vary from person to person. Nevertheless, the real cause of worry is the progressive nature of the disease. Due to this, it is, in fact, sometimes referred to as Progressive Systemic Sclerosis. 

Causes of Systemic Sclerosis 

It is an autoimmune disorder in which the immune system attacks the skin and precipitates the problem. The attack by Immune System precipitates increased collagen production in the body, which accumulates in the skin tissue. This leads to changes in characteristics and the appearance of the skin. 

Symptoms of Systemic Sclerosis 

Systemic Sclerosis affects only the skin in the early stages. It may lead to thickening of skin and development of shiny areas around bony areas, such as nose, mouth, fingers etc. However, as the disease progresses, it may limit movement of these affected areas. So one may have a problem in opening the mouth, parting fingers etc. 

Other symptoms are: 

  Loss of hair 

  Deposit of lumps under the skin 

  Blood vessels under the skin getting dilated 

  Pain in the joints 

  Breathing difficulties 

  Dry cough 

  Constipation 

  Diarrhea 

  Swallowing difficulty 

  Reflux of food from esophagus 

  Feeling of bloating after taking meals 

In addition to the above, one may also sometimes experience spasms in the blood vessels of fingers and toes. Legs and hands may turn blue or white if a person is undergoing emotional stress or is in extreme cold. This is also known as Raynaud s phenomenon. 

Risk Factors

Though the causes of the disease are not yet known, there are some risk factors which can make a person susceptible to this disease: 

  If a person is undergoing chemotherapy with certain drugs like Bleomycin or are exposed to stuff like silica dust, organic solvents etc., one may become susceptible to this disease. 

  Women are more prone to acquiring this disease than men. 

  If a person is a Native American or an African-American then too he/she is more susceptible to this problem. 

Treatment of Systemic Sclerosis 

Systemic Sclerosis can t be cured, but its symptoms can certainly be reduced to some extent. So, treatment is specific to symptoms one is experiencing, and may include using the following: 

  corticosteroids 

  immunosuppressants 

  nonsteroidal anti-inflammatory drugs 

  blood pressure medication 

  aid to resolve breathing difficulty 

  physical therapy, light therapy etc. 

The fact that this disease really can t be fully cured makes this a pretty scare disease. Silver lining is that medication and other treatment options are able to suppress most of the symptoms.

Systemic Sclerosis - What Causes It?

With age, most body organs begin to deteriorate in their function. This happens to the brain also, thereby reducing the overall speed of functioning of most organs. While slowing of bodily movement is visible, the internal organs functioning also slows down, which is not that obvious. Memory loss or dementia is one of the main manifestations of this degeneration of the brain.

Alzheimer s is the most common form of dementia, and the associated symptoms includes reduced reasoning abilities and cognitive defects. Though it is seen only in the elderly, not all elderly people will have Alzheimer s. The overall quality of life of the affected person is reduced with difficulty remembering things that were recently learned. It is a progressive disease and as it gets more severe, a full-time caretaker may be required.

Causes: The brain cells are affected by protein masses known as plaques and tangles. These hamper the way communication between the brain cells happens as well as affect nutrition from reaching all parts of the brain. This leads to shrinking of the brain, eventually leading to memory loss and other problems. There is also a strong genetic linkage, as most people with Alzheimer s have the lipoprotein A gene.

Symptoms: Though memory loss is the most common symptom, there are other symptoms:

Being confused about places, people, and times
Inability to find the right words during conversations
Regular objects are misplaced
Becoming irritable, (in someone who was not so previously)
Mood swings
Personality changes
Inability to organise thoughts
Not able to make the right decisions
Repetitive talks and actions
Forgetfulness (not something the person always does)
Difficulty with numbers (again, not something calculations
Difficulty managing everyday tasks and minor problems
Suspicion of others (like immediate family members and friends)
Risk factors: While age is definitely a risk factor, the fact that not all aged people develop Alzheimer s is to be borne in mind. Other risk factors include the history of stroke, high cholesterol, high blood pressure, diabetes, smoking, obesity, and poor lifestyle choices.

Diagnosis: While there is no definitive way to diagnose Alzheimer s, symptoms along with brain scans and neuropsychological function testing are useful ways to confirm the diagnosis.

Treatment: This is aimed at two things reducing the rate of disease progression and treat (or reverse) symptoms if possible.

Cholinesterase inhibitors improve cellular communication in the brain and also manage depression and agitation. Memantine is used to slow the pace of disease progression.
In people with the disease, small changes are useful to help them with the symptoms. These include keeping essential things like keys and wallet in the same place, keep a daily diary to help them remember things, keep pictures of friends and family within visible distance.

Alzheimer's - An Overview!

Firstly, what you need to realise is that Alzheimer s is not dementia and the main point you need to remember about the difference between the two is that the former is a disease while the latter is a syndrome. Alzheimer s is a neurodegenerative disease, it breaks down the cognitive functions of the brain and reduces a person s ability to function properly. It s one of the foremost reasons for untimely senility in middle-aged to old-aged persons.

It can be a scary time for the patient themselves as well as for friends and family alike but fear not, there are ways to reduce the chances of suffering from this painful predicament. Here are a few easy hacks to keep in mind to stave off the risk of Alzheimer s:

Fix your diet: Cut down on saturated fats and construct a diet combining lots of healthy vitamin and mineral rich foods, fruits and vegetables. Vitamin E is essential as well as vitamin B12 which can also be taken in the form of supplements. Vitamin E can be found in foods like spinach and even nuts. Rush University Medical Centre in Chicago has, after a lot of research, developed the MIND and DASH diets. The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet collates portions of the DASH (Dietary Approaches to Stop Hypertension) diet to create the perfect combination that has been shown to reduce the risk of Alzheimer s by 53 percent.
Exercise mental and physical: A sedentary lifestyle is one of the major causes of Alzheimer s because it leads to slower brain activity and an overall unhealthy lifestyle. To break out of this you need to regularly exercise and not just physical exercises but also mental exercises such as solving mental maths and crosswords and reading books and newspapers. There are a lot of apps concerning games that help boost brain activity on the market that can help as well. Physical exercise can include swimming, brisk walking, joking and even gardening.
Reduce stress: Stress proves to be a huge issue for the brain contributing to its damage by putting a lot of pressure on it. Try to relax more by improving your sleep cycle, resting as and when required, and not overworking yourself.
Aromatherapy: Essential oils have been shown to work wonders, by reducing stress and relaxing the mind. Lavender, rosemary, lemon and even orange are some great options you can try out. These oils can help rejuvenate damaged brain and nerve cells.
Meditation: Studies have shown that regular meditation helps boost grey matter in the brain, and along with yoga, keeps the minds and bodies of middle-aged people active and better focused contributing to the overall health of the brain.

Life Hacks! How To Beat Alzheimer's

A migraine often causes throbbing pain at one side of the head accompanied by sensitivity to sound and light, nausea and vomiting. The pain can last from a few hours to few days. Some warning signs of the pain take over include tingling of the leg or face, flashes of light and blind spots. Medication can help in avoiding the pain or manage it considerably.

Diagnosis:
Detection of a migraine is fairly easy for a medical professional. If a patient has a family history of a migraine, a doctor can prescribe the following to lock in on the diagnosis:

Blood tests: Through blood tests, a doctor tries to understand any possible problems in the blood vessels, spinal cord or presence of other toxins in the system
Magnetic Resonance Imaging: Better known as MRI, this is a process of capturing the detailed image of the blood vessels and the brain. It readily detects any possible problems related to a migraine.
Computerized tomography: More commonly known as CT scan, this is a process of capturing an image through a line of x-rays to detect any possible problems related to a migraine.
Lumbar puncture: This test is prescribed in extreme cases when a doctor suspects that there is a possible chance of bleeding in the brain.
What are the treatment options available?
There are two kinds of medications available- preventive medication and pain relieving medication. The treatment strategy is decided based on the frequency of the headaches and other health factors.



Some pain reliever medication includes triptan, ergots, opioid, glucocorticoids, anti-nausea medications etc. These medicines constrict the blood vessels and block the pathways of the pain in the brain cells. While some medicines are required to be consumed immediately after the symptoms starts, some should be taken regularly to avoid the pain in the first place. These pain relievers have side effects and should be consumed after prior discussion with a doctor.



Preventive medication, on the other hand, is only suggested by a doctor when a patient suffers from a migraine twice or more in a month, the pain lasts for more than 12 hours and the pain relievers do not work. Some of the common group of medicines that are suggested for these set of patients include cardiovascular drugs, anti-seizure drugs, anti-depressants etc.

Alternative medicine approach:
Alternative medicines are often witnessed to fetch positive results for migraine patients:

Acupuncture: this form of treatment involves inserting thin needles into the skin at various points to give relief from pain
Cognitive behavioral therapy: This is a form of treatment which focuses on perceiving pain with behavioral changes.
Biofeedback: This is a relaxation technique that teaches to control physical responses such as pain, stress, muscle contraction etc.
In case you have a concern or query you can always consult an expert & get answers to your questions!

Migraine - Treatment Options Available!

Heavy medication is often not required to treat fatigue. Homeopathy is an effective approch to deal with fatigue as it stimulates the body to heal itself. In most cases, simply replenishing phosphate cell salts in the body can have a beneficial effect and give you more energy. These salts help regulate disturbances in the constitution of a person at a cellular level. Phosphorus salts or phosphate compounds can be found in our body fluids, tissues and organs. These salts are essential for energy production, communication between cells and other regulatory responses. It is also vital for healthy bones, teeth and membrane structures. 

Take a look at these five cell salts and how they can revitalize you and help fight fatigue.

Calcarea phosphate: This compound is a building block cell salt. It is essential for the healthy growth of teeth, bones and blood cells. It helps with a number of conditions created by structural stress and helps fight tiredness and restlessness. It is also a beneficial tonic for children exhausted by long periods of mental exertion such as studying. 
Ferrum phosphate: This is an iron compound that is critical to the health of blood cells. By fighting cold, cough and slight fever in the initial phase, it keeps the body healthy and helps build up the immune system. When alternated with calcarea phosphate, the iron in this cell salt is absorbed more easily. Thus Ferrum phosphate can also help regulate the hemoglobin levels in the blood and reduce physical weakness and fatigue. 
Kali phosphate: This potassium and phosphorus compound is considered as a nerve nutrient cell salt. It can be used to treat agitation and depression by calming the nerves. It also fastens the healing of damaged nerve structures. It can also help treat insomnia that follows a day of excitement and physical strain.
Magnesium phosphate: This is an antispasmodic cell salt and is also known as the homeopathic asprin. It is essential for well structured muscles and their connective tissues. Magnesium phosphate helps muscles move smoothly and can be used to treat minor spasms, radiating pains and to relieve pen up tension and cramps. It can also ease painful menstrual cramps.
Natrum phosphate: The body depends on this compound to break down acids and help with the digestive system. Thus this is considered as an acidity cell salt, which also helps with issues like headache, muscle ache, stiffness and fatigue.

Battling Fatigue with Cell Salts

Our body is composed of many elements that carry out emotional and physical functions that are usually in sync with one another. It is important for these organs and other elements to be in sync for good health. All nerves are connected to the brain and are responsible for sending important signals throughout your body. Therefore, even one pressed nerve may send you warning signals such as pain to the body. It is advisable not to overlook these signals. Damage from a pressed nerve might be minor or extreme. It might bring about persistent and chronic issues. Therefore, the sooner you get a treatment for nerve compression, the more relieving experience you will have. In a few cases, you cannot reverse the damage caused by a pressed nerve. However, treatment does relieve you from the pain in most cases.

Nerves are the most vulnerable at spots in your body where they go through narrow spaces and have very less tissue to protect them. These are the places they are more likely to get pinched. A number of the causes may include:

If the nerve is pressed between tissues, for example, your tendon, ligament or bone.
Nerve compression in your neck or arm may likewise bring pain in zones, for example, your elbow, hand, wrist or fingers.
Aggravation or weight on a nerve root leaving the spine may bring about neck or low back pain.
In case a disc tears, it is known as a herniated circle that can put weight on a spinal nerve.
Some of the common symptoms of pinched nerves are:

Pain in the region of pressure, for example, the neck or low back
Transmitting pain, for example, sciatica or radicular pain
Numbness
Tingling
Blazing sensation
Weakness
To what extent you are affected depends from individual to individual. Treatment fluctuates, based upon the seriousness and reason for the pinched nerve. You may find that you benefit from just resting the affected area and by maintaining distance from any exercises that may cause you harm. If side effects endure or torment is serious, it is best to see your specialist. You may require one or more types of treatment to contract swollen tissue around the nerve.

Treatment may include:

NSAIDs - Non steroidal inflammation mitigating drugs (NSAIDs, for example, headache medicine, ibuprofen, or naproxen may diminish swelling).
Oral corticosteroids - These are utilized to lessen swelling and agony.
Opiates - These are utilized for brief periods to lessen extreme pain.
Steroid infusions - These infusions may diminish swelling and allow the affected nerves to recover.
Exercise based recuperation - This will extend and reinforce muscles.
Brace - A prop or delicate neckline limits movement and permits muscles to rest for brief periods.
Interventional Pain Procedures: They are the most cost effective and non invasive methods for pain relief as recommended by the WHO. Your pain will be taken care of by the interventional pain physician or the pain specialist.
Surgery - Surgery might be required for more serious issues that do not react to different sorts of treatment.

What to Do When You Have a Pinched Nerve?

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