Alzheimer's disease is a neurodegenerative disorder that causes a degradation and eventually death of the brain cells. People with Alzheimer's disease suffer from a memory loss. There is also a progressive decline in the cognitive capacity of the brain.Today, Alzheimer's disease and dementia have become almost synonymous with old age. It is a heartbreaking experience to see aged people with Alzheimer's disease. They have little or no memory of the present time, of their loved people or the things around them. 

The Alzheimer's disease starts off as a mild condition and then gradually progresses through stages. In this article, we will discuss the different stages associated with Alzheimer's disease.

The first stage: This stage shows no significant changes in the affected person. Thus, without any diagnostic tests (such as a PET scan), it will be difficult to detect the condition in the initial stage.
The second stage: This stage brings about some changes in the person. The person might misplace things or may even forget words (something that is often brushed aside as a small problem). However, this seldom interferes with their daily activities. Like the first stage, this stage, in most cases, goes unnoticed.
The third stage: This is the stage that brings about visible changes in the person concerned such as
The person experiences difficulties in trying to organize things.
They forget things they have read, or heard just a few seconds back.
In some cases, the person may not be able to recollect a person's name they have just met.
Some people may end up repeating the same question over and over again.
The fourth stage: This stage marks a further decline in the mental health. The person gets forgetful about himself or herself. They also start mixing up with the dates and months or makes major goof up while cooking (misses out on ingredients).
The fifth stage: The mental deterioration reaches a step further. The person slowly starts forgetting about the present, such as their address, the time of the day, their profession and even phone numbers.
The sixth stage: The problem is getting worse. Hallucination is slowly setting in. The person is starting to forget people and their faces, mixing one identity with another.
The seventh stage: The final and unfortunately, the worst stage. The person stops talking to people, eating, or even walking. They stay confined to their world, oblivious of their immediate surrounding.
Dealing with an Alzheimer patient

In addition to the treatment and medication, a person with Alzheimer's disease needs the love, care, and support of their close and dear ones. Isolating them will only worsen the situation.
It may not be easy to deal with an Alzheimer's patient as the disease progresses, but do not be rude to them. Give them the confidence.
Always keep a paper containing their name, address and emergency contact number in their wallet.
People after the age of 50 should undergo regular health check ups.

Alzheimer's - How The Disease Progresses?

Epilepsy is a form of chronic disorder and it is characterized by recurrent seizures. The episodes of epileptic seizures may differ from person to person. These seizures could be a result of genetic disorder or a result of trauma or stroke. During a seizure, a patient may also experience symptoms of neurological disorders and sometimes lose consciousness.

Medical help for epilepsy
Epilepsy itself cannot be cured using medication, but proper medicines help in eliminating recurrent seizures. These medicines stabilize the electrical activity within the brain preventing seizures.

How effective is the medication for epilepsy?
The success of controlling seizures using medicines depends on the type and severity of epilepsy. Medicines for epilepsy are usually very effective and may fully keep seizures under control. However, controlling seizures caused due to brain problems may be more difficult. Usually, epilepsy medicines can control seizures for a long period of time when they are taken regularly.

When is medical help needed?
The decision about when to start medicines for epilepsy is a tricky one. This is because a first seizure cannot confirm whether a person has an on-going epilepsy problem. A second seizure may occur after many years or may not happen at all. Prediction of seizures is also quite difficult.

The severity of seizures also indicates when to start medicines for treatment. In case a first seizure is quite severe, medication should be started at once. Some people have very mild seizures even though they may be recurring in nature, and medication can be avoided in this situation. After first seizure MRI and EEG may help to know whether you have the risk of second seizure or not.

All the pros and cons must be thought over before starting medications for the treatment of epilepsy. It is advisable to wait for a second seizure and then start medications for treatment. In most cases, medication is started after a second seizure occurs, twelve months within the first seizure. You should always consult a doctor to know when you need to start taking medicines to treat the condition.

For making the most out of the medicines to control seizures, you should follow certain steps:

You must take medications exactly as your doctor has prescribed.
Before switching to generic versions of your medicines or before taking other prescribed medicines, you must consult your doctor.
You should never stop taking the medicines.
In case you experience enhanced depression, mood swings and suicidal thoughts, you should talk to your doctor immediately.
In case you have migraine, you should let your doctor know so that he can prescribe you anti-epileptic medicines, which also prevent migraines.
Medicines cannot treat the underlying cause of epilepsy, but these help in controlling seizures and this is the most common symptom of epilepsy. Medication should be started at a proper time and must be continued without stopping.

When to Seek Medical Help for Epilepsy

Surgery to remove abnormal growths of the brain, peripheral nervous system or the spine or any disorder can be tricky because the brain and the skull that shields it are complex areas. In the old days, open surgery was the only way to access the brain or spinal cord. But, with the invention of laparoscopy, keyhole surgery to treat neurological issues is gaining ground.

What is Neuroendoscopy? 
Neuroendoscopy is a surgical procedure that is favoured by doctors and patients alike because it is minimally invasive.
Before the surgery, you will be administered general anaesthesia so that you will be unconscious during the entire duration. During the surgery, the surgeon will drill a minute hole into your skull just above the eyebrows. You skull also has two natural openings. That is why the surgeon may make use of the nose or the mouth to access the region that needs to be operated upon.

Neuroendoscopy is useful because -

  It lets the surgeon reach regions that are not accessible with open surgery
  The tumour can be removed without any damage being done to surrounding tissues

An endoscope is a delicate device with a high-resolution camera mounted on it. There is an eyepiece on the other end. The device is also fitted with a light. When it is inserted into the brain, it lights up the passage and the eyepiece allows the surgeon to take a look inside. The camera sends a live feed of the path it is traversing and this guides the surgeon. When the tumour is reached, it is gently removed with other surgical instruments that too were inserted through the cavities or the drilled hole.

Benefits of Neuroscopy -
There are several advantages of relying on laparoscopy -

  The patient endures less pain
  Fewer chances of infection
  Faster recovery
  Very little scarring of tissues

Which Disorders call for Neuroendoscopy?
Any of the following disorders can be put to rights with a neuroendoscopic surgery -

  Pituitary tumours
  Rathke s cleft cysts
  Pineal area tumours
  Ventricular tumours
  Skull base tumours
  Brain inflammation triggered by an infection
  Chordomas
  Cerebrospinal fluid fistulas
  Trigeminal neuralgia
  Cerebral aneurysm

After Surgery-
Once you undergo the neuroendoscopic surgery, you will have to be rehabilitated so that your condition can be monitored round the clock. Neuroendoscopy is a state of the art clean and efficient surgery that is beneficial to both surgeons as well as the patients.

Know More About Neuroendoscopy And Its Uses!

In recent times, the advancement of medical science has substantially contributed in comprehending the Alzheimer s disease. Unfortunately, the number of individuals suffering from the disease is expected to rise in the next ten years which pose a threat to the allocation of health care resources and public health. Alzheimer s disease is thought to be a complex disease which influences a person s behavior as well as cognition through numerous mechanisms.

Can surgery be deemed as a treatment for Alzheimer s disease?
The surgery is a multicenter clinical trial which is making a new direction in clinical research. It is devised to halt or slow down the problems caused by the disease which gradually erases a lifetime of memories in elderly patients. Though there is no cure for Alzheimer s disease, it has been found that low-voltage electric charges delivered right at the brain. Only the symptomatic therapies for Alzheimer s disease are provided which do not have any effect on the evolution of the disease. The standard medical treatments for Alzheimer s disease include cholinesterase inhibitors along with a partial N-methyl D-aspartate antagonist. In most cases of mild to moderate symptoms of this disease, a combination of treatments is used according to the clinical history, age and condition of the patient.

Mental activity supporting cognition
Many patients having normal cognition or mild impairment have a fear that they may develop AD. Many experts are of the opinion that mentally challenging activities including brain teasers and crossword puzzles can be helpful in reducing the risks in such patients. Clinical trials are under the way for determining whether or not these types of activities have any substantial effect on halting the progression of AD.

Treating AD in its moderate to the severe stage
Numerous studies have shown that blockade of NMDA receptors by memantine can be used safely in combination with ChEls. This combination has been shown to delay the institutionalization in patients with Alzheimer s disease.

Treating secondary symptoms
A variety of behavioral as well as pharmacologic interventions can help in overcoming the clinical manifestations of the disease. These include anxiety, psychotic behavior, depression and agitation among others. The effectiveness of this disease can range from modest to excellent. No particular agent or dose of it can be unanimously accepted to be the sole treatment option for the wide range of clinical issues. Moreover, in the recent time, the FDA has not accepted any psychotropic agent for treating AD.

Along with these treatment options, there are behavioral interventions that can range from patient-centred approaches to caregiver training for helping manage the cognitive and behavioral manifestations of Alzheimer s disease. Last but not the least, it is very crucial to point out the significance of treatment in the early stages of AD in order to cure it better.

Alzheimer's Disease - Can Surgery Help You Treat It?

Autoimmune disorders are one of the least understood disorders in the whole of medical science. Systemic Sclerosis is also an autoimmune disorder in which the skin undergoes changes in texture and characteristics. 

However, the changes are not confined to the skin alone. It can affect blood vessels, muscles, digestive system, heart, kidneys, as well as the lungs. It typically affects people in the age group of 30 to 50 years, but the good thing is that doctors can diagnose this at any age. 

It has been observed that more women fall prey to this disorder than men. The severity of symptoms may also vary from person to person. Nevertheless, the real cause of worry is the progressive nature of the disease. Due to this, it is, in fact, sometimes referred to as Progressive Systemic Sclerosis. 

Causes of Systemic Sclerosis 

It is an autoimmune disorder in which the immune system attacks the skin and precipitates the problem. The attack by Immune System precipitates increased collagen production in the body, which accumulates in the skin tissue. This leads to changes in characteristics and the appearance of the skin. 

Symptoms of Systemic Sclerosis 

Systemic Sclerosis affects only the skin in the early stages. It may lead to thickening of skin and development of shiny areas around bony areas, such as nose, mouth, fingers etc. However, as the disease progresses, it may limit movement of these affected areas. So one may have a problem in opening the mouth, parting fingers etc. 

Other symptoms are: 

  Loss of hair 

  Deposit of lumps under the skin 

  Blood vessels under the skin getting dilated 

  Pain in the joints 

  Breathing difficulties 

  Dry cough 

  Constipation 

  Diarrhea 

  Swallowing difficulty 

  Reflux of food from esophagus 

  Feeling of bloating after taking meals 

In addition to the above, one may also sometimes experience spasms in the blood vessels of fingers and toes. Legs and hands may turn blue or white if a person is undergoing emotional stress or is in extreme cold. This is also known as Raynaud s phenomenon. 

Risk Factors

Though the causes of the disease are not yet known, there are some risk factors which can make a person susceptible to this disease: 

  If a person is undergoing chemotherapy with certain drugs like Bleomycin or are exposed to stuff like silica dust, organic solvents etc., one may become susceptible to this disease. 

  Women are more prone to acquiring this disease than men. 

  If a person is a Native American or an African-American then too he/she is more susceptible to this problem. 

Treatment of Systemic Sclerosis 

Systemic Sclerosis can t be cured, but its symptoms can certainly be reduced to some extent. So, treatment is specific to symptoms one is experiencing, and may include using the following: 

  corticosteroids 

  immunosuppressants 

  nonsteroidal anti-inflammatory drugs 

  blood pressure medication 

  aid to resolve breathing difficulty 

  physical therapy, light therapy etc. 

The fact that this disease really can t be fully cured makes this a pretty scare disease. Silver lining is that medication and other treatment options are able to suppress most of the symptoms.

Systemic Sclerosis - What Causes It?

Sleep apnoea is a kind of disease that can affect people of any age and is basically a kind of sleep disorder. The person suffering from sleep apnoea may feel extremely tired and fatigued even after having a full night s sleep and his snoring may become extremely loud which is again a serious problem.

What are the symptoms of sleep apnoea?

There can be many cases where the symptoms of central sleep apnoea and complex sleep apnoea may be overlapping which makes it a bit difficult to get diagnosed properly. But, there are certain very basic symptoms of sleep apnoea.
Very loud snoring is a basic characteristic of patients with sleep apnoea.
The patient may suffer from regular episodes of cessation when they are sleeping as might be pointed out by other people.
The patient may awaken from sleep regularly due to shortness of breath and problems in the sleeping order.
The patient suffering from sleep apnoea may wake up from sleep with a very dry mouth and or a sore throat.
The patient may suffer from a bad headache often and in many unfortunate cases, the patients may also suffer from insomnia which is the problem of sleeplessness.
Patients of sleep apnoea suffer from intense problems of irritability and bouts of morning sleepiness.
Shortness of breath may intensify in a patient so much so that the person may get awakened from sleep gasping for air as if choking.
Excessive bouts of daytime sleeping may cause a person to perform very poorly in his work as well.
It is at these times when a patient should immediately consult a doctor for a proper treatment and further solution to this problem.

Causes of sleep apnea

Obstructive sleep apnoea is caused when the muscle in our throat starts relaxing. It is this muscle that gives support to the triangular piece of tissue that hangs from the uvula which is the soft palate and the side walls of the tongue. Basically, when this muscle relaxes, the airways in the body gets narrowed as a result of which the blood does not get enough oxygen which is required for proper breathing. It is then that the brain starts sending signals to get up from sleep so that the nasal passage can be reopened for sufficient amount of oxygen.
There can also be cases where the brain is unable to send a proper signal to the muscles that help us to breath as a result of which a person does not breathe for a certain period of time. This, in turn, makes the patient awaken abruptly from sleep with shortness of breath and the patient finds it difficult to fall asleep.


Sleep Apnea - Know The Common Signs Of It!

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