The body has multiple chemicals called hormones, which regulate many of its functions. Increased or decreased levels of these hormones affect various functions including metabolism, growth and sexual functions. Thyroxin produced by the thyroid (situated in the front of the neck) is one such hormone, which has a significant role to play in metabolism.

Graves  disease is one of the main causes of hyperthyroidism, where there is excessive production of thyroid hormones. Graves  disease is an autoimmune disorder, wherein the body reacts against its own tissues. It is very common in women than men, especially after 20 years of age. Family history also has a strong correlation in developing Graves  disease. The high levels of thyroid hormone increase the rate of metabolism, thereby altering weight, mental energy levels, physical stamina, and also mood.

Thyroid hormone is related to metabolism and more amount of it lead to higher metabolism. This causes the following symptoms.

    Intolerance to heat
    Excessive sweating
    Nervousness and anxiety
    Inability sleep, as the mind is always excited
    Increased appetite (sometimes despite weight loss) due to higher metabolism
    Irregular menstrual cycles
    Palpitations (rapid, loud heartbeat)
    Irregular heartbeats (tachyarrhythmia)
    Fine tremors of the extended arms
    Breast enlargement in men, known as gynecomastia
    Extreme moodiness, causing irritability and anger
    Inability to focus and concentrate
    General fatigue and shortness of breath with any exertion
    Increased frequency of bowel movements

In addition, the eye symptoms are quite diagnostic including:

    Protrusion of the eyes (exophthalmos), giving an impression that they are going to fall out
    Double vision
    Excessive tearing
    Increased irritation in the eyes

Diagnosis: The first symptom would be the presence of an enlarged thyroid gland (front of the neck above the collarbone), and the some of the above symptoms would be present.
In addition, tests to check for thyroid gland functioning including T3 and T4 levels would reveal increased amounts of hormone in the blood stream.
As a confirmatory test, the radioactive iodine uptake test also is done, which will indicate increased uptake by the thyroid gland. This indicates that the gland is functioning at an increased pace and requires additional iodine for the production of thyroid hormones.

Treatment: There are two approaches to it, one to control the symptoms and the other to control the thyroid gland per se.

    Beta blockers are very useful in controlling rapid heart rate and anxiety.
    Prednisone may be used to control eye irritation and swelling
    Antithyroid drugs are used to control the production of thyroid
    Radioactive iodine is given orally to control excessive thyroid production
    In severe cases, thyroid gland may be surgically removed partially or completely

Graves  disease is not life-threatening and once symptoms are controlled, the patient s quality of life improves drastically.

Graves' Disease - Things You Should Know About It

Diabetes is one of the most common problems that are caused by obesity, unhealthy and inactive lifestyle. It is a metabolic disorder in which the body is unable to store and use energy from food. Being physically inactive and eating unhealthy food are primary causes of diabetes. It is a long term condition, which causes high or unstable blood sugar levels in the body.

When a patient suffers from low blood sugar it is called hypoglycemia and if the blood sugar levels are too high, it is called hyperglycemia. Both are extremely harmful for a patient.

Type 1 and type 2 and gestational diabetes:

Type 1

In type 1 diabetes, the body does not produce insulin. The condition has no known cure and is usually hereditary in nature. Approximately 10% of those suffering from diabetes have type 1 diabetes. Patients with type 1 diabetes have to take regular medication, including insulin injections as well as take care of their diet.

Type 2

Type 2 diabetes happens when the body does not produce enough insulin for its proper functioning. 90% of all diabetic people suffer from type 2 diabetes. It is usually caused by poor lifestyle choices, like physical inactivity and unhealthy food habits. The disease lasts a lifetime and is usually progressive in nature, but can be managed by taking regular medication, choosing an active lifestyle and maintaining proper body weight.

Gestational diabetes

Diabetes during pregnancy is known as gestational diabetes. This has to be managed by taking medication or in extreme cases insulin shots. If undetected or untreated, gestational diabetes increases complications during childbirth, and causes unusual weight gain in the baby. However, gestational diabetes usually ends after the baby is born and women can go back to their normal lifestyle and eating habits post delivery.

Symptoms of diabetes

 Frequent urination
 Extreme hunger or thirst
 Weight loss
 Problems with vision
 Tingling or numbness of the extremities.
 Unexplained fatigue
 Dry skin
 Cuts or sores that heal slowly
 High number of infections

Who is at greatest risk for developing diabetes?

People who:

 Are 45 or over
 Are overweight
 Are habitually physically inactive
 Have previously been identified as having ifg (impaired fasting glucose) or igt (impaired glucose tolerance)
 Have a family history of diabetes
 Are members of certain ethnic groups (including asian american, african american, hispanic american, and native american)
 Have had gestational diabetes or have given birth to a child weighing more than 9 pounds
 Have elevated blood pressure
 Have an hdl cholesterol level (the good cholesterol) below 35 mg/dl and/or a triglyceride level above 250 mg/dl
 Have polycystic ovary syndrome
 Have a history of vascular disease

What is pre-diabetes?

Pre-diabetes is a condition of elevated blood glucose level that has not yet reached a diabetic level. Along with insulin resistance, pre-diabetes causes no symptoms. An individual may be pre-diabetic for years without knowing it. Pre-diabetes increases your risk of developing type 2 diabetes and heart disease. Weight loss and exercise may halt the onset of diabetes from pre-diabetes by returning blood glucose levels to a normal range.

Diabetes: At A Glance

Diabetes is a condition that affects the pancreas to the extent that it does not release the required quantity of insulin, which can lead to a high blood sugar level as the body starts to absorb excess glucose from the food that it ingests. This can be of various types and have different implications for different patients. While many experts insist that keeping a low cholesterol level and low weight is a primary requirement for the treatment of diabetes patients, there are a number of myths in this regard. Not eating fat is one such myth that we are out to prove wrong today.

So read on to find out why diabetic people need to eat fat:

Saturated Fats and Trans Fats: There are studies that demonstrate how saturated fats can actually prove to be beneficial for diabetes patients. These can be found in various sources like fish and nuts. This releases heptadecanoic acids, which can normalise the blood sugar levels as well as the insulin and triglyceride levels in the body.
Dairy Fat: The use of milk and yogurt as well as butter can actually be helpful in bringing the blood sugar levels down. It also shows up favourably on the lipoprotein markers. Butter, in particular, is known to have clarifying properties that can bring down the risk of diabetes as well. One must take care to use dairy products that are fat-free. 
Animal Fat: Having meat which releases fat and having dairy products like cheese and milk which releases healthy saturated fats are two different things. One can replace carbs and meat with these kinds of products so that there are better absorption and creation of quality animal fats which can actually help the insulin levels.
Monounsaturated and Polyunsaturated Fats: Food items like fish and nuts that carry high levels of Omega-3 fatty acids as well as monounsaturated and polyunsaturated fats can help patients suffering from diabetes by clearing the bloodstream of cholesterol and high lipid levels. This also prevents the risk of heart disease and arterial blockages. These kinds of fats are also found in flax seeds, soya products and walnuts. 
Going low on carbohydrates and avoiding sugar is usually recommended for patients suffering from diabetes. Yet, it is important to have your fill of essential fats as mentioned above with the help of dairy products, clarified better, omega three fatty acids, dry fruits, soya products and some amount of vegetable oils, as these actually have a number of benefits for these patients.

Why Do Diabetic People Need To Eat Fat?

Female infertility is considered as the inability of conceiving. As per WHO it is described as the inability to be pregnant, maintain and carry forward a pregnancy to its full term. It is often of two types:

    Primary Infertility: This is the inability to give birth to a baby either due to the inability to become pregnant or maintain a pregnancy, which includes stillborn and miscarriage.
    Secondary Infertility: This refers to the inability to give birth when there is already a live birth or the woman was pregnant.

The causes of infertility can vary from being acquired or genetic. However, following factors are largely responsible for infertility:

    Genetic: Some genes can lead to mutation leading to infertility like, in case of BMP15 gene there is a hypergonadotrophic ovarian failure which causes infertility.
    Acquired: This is caused by factors like age, smoking, sexually transmitted diseases, obesity, body weight, eating disorders, diseases like diabetes, thrombophilia and also radiation and chemotherapy.

The treatment for infertility usually depends on the cause, age, duration of time for which a person has been infertile and preference of the patient. Infertility is believed to be a complex disorder and the treatment involves a huge amount of physical, financial and psychological commitments. All this also requires a lot of time. Some women might need just a minimum of two therapies to attain fertility while others might require different treatment before they can conceive.

Treatment is largely aimed to restore the fertility either by means of medication and surgery or help in reproduction with the help of some procedures.

Fertility Restoration through medication

This is the main treatment for women who are infertile because of ovulation disorders. These drugs include:

    Gonadotropins: These are injected to stimulate the ovaries. Drugs like Menopur, Repronex, Follistim AQ, Gonal-F, Bravelle restore the production of eggs, while Ovidrel and Pregnyl are used for maturing the eggs and for their release.
    Clomiphene citrate: This is taken orally and stimulates ovulation by releasing more Follicle Stimulating Hormone and Luteinizing Hormone from the pituitary gland.
    Metformin: This is used in females who have PCOS and also when insulin resistance plays a major role in infertility.
    Bromocriptine: Used when the infertility is caused due to excess prolactin production.
    Letrozole: This also induces ovulation

Fertility Restoration through surgery

Surgical procedures can amend the problem of infertility. However, these treatments are very rare these days owing to the success of other fertility treatments. These include:

    Tubal ligation reversal surgery: In case a tubal ligation has been performed it can be reversed by reconnecting the tubes again through surgery.
    Hysteroscopic surgery: This corrects or removes the abnormalities that cause infertility. This surgery can correct the shape of the uterus, remove endometrial polyps and improve chance of getting pregnant.
    Tubal surgeries: In case of blocked fallopian tubes laproscopic surgery can be performed to dilate the tubes, removed blockages or create a new opening.

Assistance in Reproduction through techniques

The most common used techniques for reproduction assistance are:

    Intrauterine insemination or IUI: In this about million healthy sperms are put in the uterus at the time of ovulation.
    Assisted reproductive technology: In this mature eggs are retrieved from a woman and this is then fertilized with sperms in a dish in the lab. Once the fertilization is done the embryo is placed in the uterus for further development. IVF is the most common and effective assisted reproductive technology. This procedure takes place over weeks with several blood tests and hormone injections.

Dealing with infertility is not easy and can be emotionally and physically draining. To cope with the various tests and treatments of infertility one should be fully prepared, eat a healthy diet, exercise reach out for help and support of family and friends and look for other options like a donor egg, adoption or no children.

Treatments of Infertility

There was an era where we had deadly infections like plague and polio causing death of thousands of people. We still have occasional outbreak of swine flu, but by and large, infections are quite controlled. The new killer diseases are caused because of the lifestyle we have adapted and the damage we have done to the environment. High intake of processed foods, artificial chemicals in our foods, sedentary lifestyle with very minimal to no physical activity, couching over the computers; the list is quite long. All these have led to diseases like diabetes and cancer that were not so common about say few decades ago.

Detailed observation has revealed that both these new epidemiologic diseases have a close correlation. There are factors, which induce diabetes and diabetes in turn and in some cases, diabetes inducing agents, can cause cancer also. It has also been observed that mortality is severely increased if diabetic patients are diagnosed with cancer. There are two types of diabetes. While type 1 is mostly hereditary, type 2 is lifestyle induced and the age at which this is being diagnosed is taking a severe plunge. Adolescents and teenagers are being diagnosed for diabetes. Cancer, on the other hand, is of various types (leukaemia, melanoma, etc.) and can affect various organs (lung, breast, prostate, stomach, liver, etc.).

The medical community is yet to decipher the disease pattern of both these conditions. While there is no definite correlation between diabetes and all types of cancer, some types of cancer are definitely correlated with a definite reason identified, pancreatic and liver cancer for instance. The high amounts of insulin that diabetic patients are exposed to causes changes in liver and pancreas including fatty liver and cirrhosis, here the incidence of cancer is higher. The linkage is not very clear in lung and intestinal cancers and also there is no link between prostate cancer and diabetes.

Diabetes is considered as a state of chronic inflammation and leads to conditions like hyperinsulinemia (higher levels of insulin in the blood) hyperglycemia (higher levels of sugar in the blood). These are believed to aggravate the neoplastic process of cancer formation, thereby inducing cancer at a greater pace and also increasing the mortality rates.

The following are risk factors that are applicable to both age, physical activity, diet, obesity, drinking and smoking. It is also possible that onset of one can be followed by the other. As noted earlier, more detailed research is awaited to establish a definite linkage, but the correlation cannot be ignored at all.

Both these new epidemics are here to stay and since they have a common set of factors, we need to work on ways to contain them.

Diabetes and Cancer: The New Epidemic?

There are some commonest misconceptions about infertility and these misconceptions should be eliminated as soon as possible so that the actual facts can be known. There are many online sites where you can find detailed information on the scientific explanations regarding infertility and you can follow them.

List of myths and facts regarding infertility

1. Myth: The menstrual cycle of a woman is for 28 days.
Fact: Normal cycle ranges between 21 to 36 days.

2. Myth: A woman can have pregnancy on the day one of menstrual cycle.
Fact: The released eggs remain viable for almost 12-14 hours and a woman can get pregnant after an intercourse done two days after ovulation and five days before ovulation.

3. Myth: Infertility occurs due to stress.
Fact: Ovulation can surely get delayed due to hormone suppression, but infertility does not occur due to stress.

4. Myth: Sperms stay active for few hours.
Fact: Sperms stay alive at least for five days.

5. Myth: Men with a higher sexual drive will have a normal sperm count.
Fact: There is no relation in between fertility and virility. Sometimes, it has been found that men having a higher sex drive do not produce sperms.

6. Myth: Women have to wait for three months to conceive after stopping the usage of contraceptive pills.
Fact: As soon as a woman stops pill usage, hormonal levels go back to normal condition, as a result of which ovulation begins immediately.

7. Myth: Only females have infertility troubles.
Fact: Both women and men suffer from infertility troubles as per the current scientific studies.

8. Myth: Ovulation occurs in a woman on the 14th day of menstrual cycle.
Fact: Ovulation can be calculated by counting 14 days backwards from the past menstrual cycle's last day.

9. Myth: Daily sex can increase conceiving chances.
Fact: During ovulation, having sex each day, especially in between 12 to 16th day of the cycle can be the best timing.

10. Myth: Fertility troubles occur at 35.
Fact: Peak fertility timing in a woman's life is 20 and this might continue until late 30s. Fertility troubles might even arrive at a younger age. With age, conception chances get declined, especially after 35.

Myths & Facts About Infertility

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