Causes and symptoms of acute tubular necrosis

Damage or destruction to tube-like structures known as tubules in the kidneys can bring about the development of acute tubular necrosis (ATN) and subsequently, acute kidney failure.

What causes acute tubular necrosis (ATN)?

A lack of supply of oxygen to the cells in the kidney is the most common cause of this condition. The reason as to why oxygen may not reach the cells and tissues of this organ could be restriction or blockage of the pathways. When this happens, the kidneys get damaged. Dehydration is the most important cause of ATN which may be because of loose motions, vomitings, heat stroke etc.

Health conditions such as diabetes, heart attack, and stroke can bring about a decrease in blood flow to the organs resulting in ATN and death of cells. Similarly, the presence of toxic substances in the blood can also lead to tubules damage and change the way the cells function in the tubules.

Other causes that may lead you to develop ATN may be medications, radiology dyes, anesthetics and chemicals that cause your body to react adversely.

In addition to these causes, a number of factors can put you at risk of ATN and there are:

- An injury to the body, more specifically your kidneys can cause clotting of the blood vessels
- An adverse response to blood transfusion
- Instances of septic shock can slow down blood flow to the organs
- A major surgery that can interrupt blood supply to the organs

What are the symptoms of the condition?

The symptoms associated with the condition can vary depending on the severity of the problem.

You may experience:

- Troubles in waking up
- Drowsy feeling even during daytime
- Feelings of lethargy
- Feelings of excessive thirstiness
- Problems with urination
- Fluid retention problems
- Instances of confusion
- Feelings of nausea



Can Acute Tubular Necrosis Cause Kidney Failure?

Urinary tract infection (UTI) is usually caused by inflammation or bacteria in the urinary tract. Pregnant mothers are most susceptible to this infection, especially after the sixth week and before the twenty fourth week of pregnancy. This usually happens due to the alterations that take place in the urinary tract during pregnancy.

Also, a growing uterus can block the urine drainage from this part of the body, leading to the accumulation of bacteria which causes infection. The symptoms are uncomfortable and even painful. These include pain and burning sensation, frequent urination, fever and chills. So how can you prevent UTI during pregnancy? we have a few tips for you!

- Hydration: The best thing you can do to both prevent and treat a urinary tract infection is to start drinking at least six to eight glasses of water in a day. Another good way to prevent and treat UTIs is with the help of cranberry juice which has powerful antioxidants that flush toxins out of your system effectively. You will, however, need to ensure that the cranberry juice is fresh and natural, without any sweeteners.

- Hygiene: Keeping yourself clean is one of the most important ways in which you can avoid UTI. It is best to clean from front to back, rather than the other way, so that you drive away bacteria and dirt. Also, make sure that you wash your private parts with warm water infused with a few drops of normal liquid antibacterial, so that you can be sure that the bacteria do not get a chance to thrive and affect your system. Also, remember to use soaps, washes and creams that have a mild formula, rather than a harsh chemical concoction. Hygiene for this area of the body includes keeping it dry.

- Diet: Your diet should have plenty of fluids and lemons or other citrus food that are rich in vitamin c, as this is a good vitamin to keep bacteria at bay. Also, you should eliminate sweet and refined products to ensure that you do not contract UTI. Other foods to avoid include caffeine and alcohol.

- Clothing: Wear airy and cotton based undergarments that are breathable and have a soft texture. This non abrasive type clothing can also help in keeping the area dry, so that bacteria does not get a chance to develop, as they typically need a damp environment for growth. Change your undergarments twice a day, if need be, and avoid wearing trousers and shorts that are too tight.

These tips and many others including urinating as soon as the urge sets in, can help in fighting the risk of contracting UTI during pregnancy.

Tips To Prevent UTI During Pregnancy

The urinary tract starts from the kidneys to the urethra where urine is passed out. Given the rich concentration of minerals and toxic wastes, it is highly prone to multiple infections. UTI, as urinary tract infections are often referred to, is one of the most common infections. In women, especially, every 1 in 2 women is affected by an UTI. Whichever part of the tract is affected, the symptoms and treatment are mostly the same. Read on to know some of the most common symptoms and treatment options for these.

Symptoms

A burning sensation with urination
Pain with urination
Burning sensation or pain in the urethra or vagina
Frequent urge to urinate, though not much urine is passed out
Sense of incomplete emptying of the bladder
Pain in the lower back on the sides of the spine
Change in the urine characteristics color, smell, or appearance
Fever or chills, maybe associated with shivering, nausea and vomiting
Causes

Most urinary tract infections are bacterial in nature, and these could find their way into the body through multiple ways.

The most common is through the urethra, which could happen due to unclean toilet habits.
Women especially are advised to wipe the urethra after each toilet visit. The bacteria from the feces can also enter the urethra due to close proximity
Use of unclean public toilets is another reason for UTIs
Tests

Though most often UTI does not require specific testing, the following are useful in confirming the diagnosis.

Culture and sensitivity: The urine is sent for a culture to identify the exact organism that has caused the infection. It also helps identify the right antibiotic which will help bring the infection under control.
Treatment:

UTIs are very common infections and though there is nothing to worry, it should be cleared completely.

Antibiotic course to get rid of the infection. Though you begin to feel better, the complete course should be completed to clear the infection.
Following culture testing to ensure the infection is cleared
Improve water intake to get rid of the toxins
Fever and pain to be controlled with medications
Healthy hygiene habits to ensure clearing of infection
Prevention:

Recurrent UTIs is a common problem, and the following can help prevent.

Ensure complete emptying of the bladder
Drink adequate water
Safe toilet habits, including before and after sex
Comfortable and clean underwear to prevent infection

Urinary Tract Infection - 8 Signs You Are Suffering From It!

You're said to suffer from the problem of acute kidney failure if your kidneys suddenly stop working and lose their ability to eliminate waste materials including excess fluids and salts from the blood. The condition usually develops quickly over a few days or even a few hours. When this happens, waste materials accumulate in your blood, disrupting the chemical balance of your bloodstream.

So, what causes this problem?

Acute kidney failure can occur because of any one of these reasons:

1. A drop or slowdown of blood flow to the kidneys - Adequate blood circulation to the kidneys is of great importance as without it the kidneys may end malfunctioning. If blood flow to the kidney is hampered, a part of or the entire kidney may die. You may suffer from acute kidney failure if blood flow to the kidneys gets impaired due to conditions like

Heavy blood loss
Sepsis (body's inflammatory reaction to an infection, which can bring about organ failure, tissue damage, and death)
Injury
Use of certain drugs
Dehydration
Burns
Heart disease
2. Urinary obstructions - A sudden blockage that hampers your kidney's ability to eliminate urine can also bring about acute kidney failure. When this happens, it leads to a build up of toxins in the body, causing an overload of the kidneys. Conditions that bring about this urinary obstruction include:

Cervical cancer
Colon cancer
Bladder cancer
Kidney stones
Enlarged prostate
Prostate cancer
3. Disease within the kidneys - Even instances of clotting within the blood vessels of the kidneys can lead to acute kidney failure. This is because if the movement of blood cells within the blood vessels gets hampered, kidneys are not able to filter out toxins from the body. The conditions and diseases that may cause clotting, and subsequently damage to the kidneys include:

Scleroderma (an autoimmune disease that affects connective tissues and skin)
Build-up of cholesterol deposits
Glomerulonephritis (an inflammatory condition of the kidney's ball-shaped structures called glomeruli)
Hemolytic uremic syndrome (a condition that occurs due to untimely death of red blood cells)
Lupus (a disorder of the body's immune system that brings about damage to the body's own organs and tissues)

3 Causes of Acute Kidney Failure!

What are kidney stones?
The primary function of the kidney is to filter the blood and eliminate the waste products through urine. The waste deposition is sometimes in the form of excessive calcium, uric acid and other undesirable contents. It may cause the urine to get highly saturated. This is when stone like formations take place inside the kidneys. Kidney stones are also termed renal lithiasis or calculi. There are different kinds of kidney stones, which are differentiated based on its varied constituents. Kidney stones cause excruciating pain and uneasiness. Frequent urination, extreme discomfort during urinating and presence of blood in the urine are some of the major signs of kidney stones. The symptoms are not evident if the stones are very small in size.

Causes of kidney stones:

Incorrect calcium intake: High amounts of calcium can lead to high calcium depositions in the kidneys. It is important to keep the calcium intake moderate. Calcium supplements must be checked if you have already included dairy products in your diet.
Abnormal rates of sodium in the body: Sodium, just like calcium, gets deposited in the kidneys.
Excessive animal protein intake: Too much of animal protein intake can make the urine turn acidic, leading to uric acid depositions in the kidneys.
Sugary, aerated drinks: These lead to undesirable waste deposition in the blood stream and eventually in the kidneys.
Inadequate water intake: Not keeping the body well hydrated can cause the urine to turn acidic and increase waste deposition.
Potential risks and complications of kidney stones:

Kidney stones may cause an infection in the kidneys which may eventually spread to the other internal organs and surrounding tissues.
Kidney stones block the ureter and cause severe pain and discomfort that make sitting, standing or any other posture difficult.
Kidney stones rarely cause kidney failures but the severe blockage and infection may cause such detrimental results in the human body.

Kidney Stones - 5 Causes Behind It!

Bladder cancer is characterized by irregular growth of abnormal tissue (tumor) on the lining of the bladder. This type of cancer may spread to the surrounding tissues or other body parts as well.

What are the causes?

Bladder cancer can be caused by environment-related factors and smoking. In fact, smoking tobacco is one of the major causes of bladder cancer around the world. The chemicals present in tobacco can irritate the bladder lining which ultimately leads to bladder cancer. It may also be caused by continuous exposure to chemicals such as dyes or leather dust and radiation. These chemicals tend to cause unusual changes in the cells of the bladder lining and causes cancer in the bladder.

It can also be caused by modifications in the dna in the cells of the bladder which may impair the functioning of the cells in the body. This can cause mutations in the bladder resulting in cancer.

What are the symptoms?

1. Presence of blood in the urine, often painless

2. Feeling of pain while passing urine

3. Back pain

4. Excessive urination

5. Infections in the urinary tract

6. Lower leg swelling

7. Pain in the bones, especially in the pelvic area

8. Weight loss

Treatment options

Treatments for bladder cancer depend on the stage of the cancer. The various treatment choices are:

Surgery - In some cases, these cancers are surgically removed by a surgeon. A type of surgery used is transurethral resection of bladder tumor (turbt) where the cancer cells are destroyed with laser by passing a thin fiber into the bladder.

Chemotherapy - In this method, medications are used to target and destroy cancer cells.

Radiation therapy - Radiation therapy uses rays such as x-ray or uv rays to destroy cancer cells in the body

Immunotherapy - This treatment boosts the immune system of the body so that it attacks the cancerous cells in the bladder.

Causes And Symptoms of Bladder Cancer

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