Nephropathy is also known as renal disease. It is any type of damage or disease relating to the kidneys. Though not everyone with diabetes has nephropathy, however, diabetic nephropathy can cause kidney failure.

How does diabetes affect the kidney?
Kidneys are responsible for taking waste out from your blood. They have a lot of tiny blood vessels to do this. High blood sugar may kill such blood vessels. Once these blood vessels are destroyed, the kidneys may not function as well or it may even lead to kidney failure.

What increases your risk of getting diabetic nephropathy?
There are several factors which increase your risk of getting diabetic nephropathy including: \
1. High blood pressure
2. High cholesterol
3. Smoking
4. Being native american, african american or of hispanic origin, for whom risk factors have proved to be magnified
5. If you have family history of diabetic nephropathy

Symptoms and diagnosis:
There are very few noticeable symptoms, which appear when you have diabetic nephropathy, except swelling in your arms and legs. The diagnosis is done by checking for a type of protein in your urine known as albumin, which is not supposed to be there. Getting the diagnosis done early is crucial.

Preventive measures
You can prevent kidney damage by doing the following:
1. Keeping your blood sugar levels under control - keep hba1c &lt; 6-7%
2. Keeping your blood pressure under control in the range of 130/80
3. Eating healthy food
4. Exercising regularly
5. Not eating too much protein
6. Not eating too much salt
7. Reducing smoke or excessive tobacco usage

Medicines for treatment
If you do get diabetic nephropathy, here are some medicines, which can help cure it
1. Ace inhibitors which are also called angiotensin-converting enzyme inhibitors
2. Angiotensin ii receptor blockers (arbs)

Possible complications
1. Blood pressure may rise
2. Triglyceride levels and cholesterol levels may rise.

All About Diabetic Nephropathy

When we talk about health, the kidneys are rarely spoken of. These unsung heroes are responsible for filtering waste out of our bodies and ensuring that only clean blood flows through our system. The kidneys are a pair of small, bean-shaped organs located at the back of the abdomen. Along with removing waste from the blood, the kidneys also balance electrolytes and control the fluid balance in the body. Thus, keeping the kidneys healthy is as important as keeping the heart and lungs healthy.

Kidney stones are the most common condition that can affect these organs. Other conditions that can affect the kidneys include inflammation of the kidneys, renal failure, nephrotic syndrome and cysts. Thankfully, keeping the kidneys healthy is easy. Here are a few things you can do to improve the health of your kidneys.

Drink plenty of water: Keeping your body hydrated is crucial to kidney health. Ideally, a person should drink a minimum of 8-10 glasses of water a day. Water helps control the production of aldosterone- a hormone that regulates blood pressure- by the adrenal glands and helps the kidneys retain enough water and sodium to balance blood volume levels. If the kidneys do not get enough water, the adrenal glands are stressed into increasing blood pressure levels.
Limit consumption of caffeine: We drink caffeine in many ways- sodas, coffee, tea etc. While caffeine may act as a stimulant and keep you focused on what you are doing in the short run, in the long run, it dehydrates the body. Dehydration can also lead to the formation of kidney stones. Hence reduce your caffeine intake and instead drink more water and fresh juices.
Quit smoking: Smoking not only affects the lungs but also damages blood vessels thus decreasing blood flow to the kidneys thus preventing the optimal functioning of the kidneys. Smoking can also increase one s risk of suffering from renal cancer.
Get regular exercise: Exercise benefits all parts of your body including the kidneys. Regular exercise reduces blood pressure and helps keep the blood moving. This can help prevent kidney diseases and a number of other conditions. Ideally, aim for half an hours exercise a day at the least.
Eat plenty of fresh fruits and vegetables: Fruits like grapes, apples and blueberries and vegetables like spinach, beets, garlic and red bell peppers help improve kidney functioning. Women should also include oestrogen boosting foods like chickpeas, fennel, tomatoes, cherries and carrots in their diet to protect themselves against kidney damage and fibrosis. Foods that are low in gluten, sugar and soy also help reduce the risk of kidney inflammation.

Kidney - 5 Things To Keep Them Healthy & Fit!

An overactive bladder is a condition that is characterized by a problem in the bladder storage function; a problem that eggs one on to urinate frequently. This condition can cause problems in your social and work life. You may isolate yourself from others and feel embarrassed about the situation.

Symptoms
If you have an overactive bladder, you may exhibit symptoms of frequent urination, involuntary leakage of urine and frequent urge to urinate. These symptoms might disrupt your daily life; so it is important to seek advice from a medical practitioner.

Causes
To better understand what causes an overactive bladder, you need to know how the urination process works. Urine is produced by the kidneys, which flows to the bladder. During urination, the urine is excreted from an opening in the bladder and flows out via the urethra. As the kidneys secrete urine, the bladder starts to fill up. During this stage, nerve signals are sent to the brain; signals that trigger your body to urinate. The bladder muscles tighten that pushes the urine out of the body.

An overactive bladder results from the involuntarily contraction of the bladder, which might happen even if the content of urine in the bladder is low. These contractions create the urge to urinate. The various causes of an overactive bladder are:

Excessive fluid intake, if your fluid intake is high, then you may have the tendency to urinate frequently.
Presence of tumors or stones in the bladder can make the bladder overactive as well.
Excessive alcohol or caffeine consumption has the same effect as an excessive intake of fluids has.
Urinary tract infections may interfere with the entire process of urination, thus causing your bladder to swell up and become overactive.
Other diseases and conditions such as constipation and an enlarged prostate can hamper bladder functioning.
Treatment
There are multiple approaches to treat an overactive bladder; your doctor may use one or a combination of multiple methods.

Medications: Medications such as Trospium and Tolterodine help in relaxing the bladder. These medications help treat symptoms of frequent urination.
Bladder injections: Botox is a protein that is injected into the bladder that causes partial paralysis of the bladder muscles. This helps in treating the constant urge to urinate. However, its effects are temporary as they last for 6-9 months.
Lifestyle modifications: Certain lifestyle modifications such as incorporating exercises to strengthen the pelvic muscles, maintaining optimal weight levels and bladder training to control its functioning can help with managing an overactive bladder.
Surgery: If the other treatments do not produce the desired results, then surgery is usually recommended. The aim of the surgery is to enhance the storage capacity of the bladder and reduce bladder pressure.

Frequent Urination - Is It A Symptom of An Overactive Bladder?

Urinary Incontinence is the sudden urine loss that occurs involuntarily in women. Some of the factors which cause urinary incontinence are pregnancy, menopause and childbirth. It should be noted that urinary incontinence by itself is not a disease, but is a symptom of other underlying disorders such as diabetes, infections and other conditions.

Causes of temporary cases of urinary incontinence include:
1. Constipation
2. Urinary tract infections
3. Excess consumption of alcohol and caffeine
4. Consuming carbonated drinks
5. Use of artificial sweeteners
6. High doses of vitamin B and vitamin C
7. Being on sedatives, muscle relaxants, blood pressure and heart medications
8. Eatables which are too spicy, acidic or sugary

However, persistence of incontinence might be due to a more serious condition. Some of the causes are stated below:

Age: The bladder muscles tend to weaken with age. This affects the bladder s urine holding capacity.
Pregnancy: Hormonal changes and increase in weight during pregnancy can cause incontinence.
Menopause: Oestrogen is responsible for the healthy maintenance of the lining of the urethra and bladder. The onset of menopause causes the oestrogen hormone levels to drop. The gradual damage of the bladder tissues causes incontinence.
Childbirth: The bladder control muscles are weakened during normal vaginal delivery, thus leading to incontinence.
Obstruction: Occurrence of tumours in the urinary tract can block the normal flow of urine which can cause incontinence.
Hysterectomy: The same ligaments and muscles support both the bladder as well as the urethra. With removal of the uterus by hysterectomy, the pelvic floor muscles are deteriorated. This leads to urinary incontinence.
Neurological disorders: Conditions such as multiple sclerosis (autoimmune disorder in which the immune system destroys the protective sheath of the nerves), Parkinson s disease (disorder affecting motor functioning of the body), brain tumours, spinal injury or strokes are capable of causing incontinence.

Different forms of urinary incontinence are classified on the basis of their symptoms:

Urge incontinence: Urge or urgency incontinence occurs when there is a leak before the person reaches the toilet.
Stress incontinence: Small amounts of urine leak out during normal physical movements such as sneezing, coughing and exercising. This happens because of the minimum stress exerted on the body, and hence, the name.
Functional incontinence: Sudden leakage of urine occurs due to external deterrents or physical disabilities such as not being able to find a toilet.
Overactive Bladder: This is characterized by frequent and urgent urination.
Overflow incontinence: A full bladder, at times, leads to unexpected leakage.
Transient incontinence: If urine leakage occurs due to temporary situations such as infections, or new medications.

Did You Know - Constipation Can Also be a Sign of Urinary Incontinence

Glomerulonephritis is a disease that is caused due to inflammation of the small filters that are present within the kidneys or glomeruli. Glomeruli eliminate the excess waste, electrolytes and fluids from the blood, discharged through urine. A glomerular disease can be either acute or chronic. If the condition arises without a combination of any other disease, it is termed as primary glomerulonephritis. Secondary glomerulonephritis is characterized by diabetes or lupus (an auto-immune disorder) being at the root of the disease. Prolonged or severe inflammation can take a toll on the kidneys.


Causes-


Nephrotic syndrome can be primary, being a disease specific to the kidneys, or it can be secondary, being a renal manifestation of a systemic general illness. In all cases, injury to glomeruli is an essential feature. Kidney diseases that affect tubules and interstitium, such as interstitial nephritis, will not cause nephrotic syndrome.


Primary causes of nephrotic syndrome include the following, in approximate order of frequency:
Minimal -change nephropathy
Focal glomerulosclerosis
Membranous nephropathy
Hereditary nephropathies


Secondary causes include the following, again in order of approximate frequency:
Diabetes mellitus
Lupus erythematosus
Viral infections (e.g., hepatitis B, hepatitis C, human immunodeficiency virus [HIV] )
Amyloidosis and paraproteinemias
Preeclampsia
Allo-antibodies from enzyme replacement therapy


Nephrotic- range proteinuria may occur in other kidney diseases, such as IgA nephropathy. In that common glomerular disease, one third of patients may have nephrotic- range proteinuria.


Nephrotic syndrome may occur in persons with sickle cell disease and evolve to renal failure. From a therapeutic perspective, nephrotic syndrome may be classified as steroid sensitive, steroid resistant, steroid dependent, or frequently relapsing.


Treatment-
Whether one is suffering from acute or chronic nephrotic glomerular , with symptoms moderate or severe, the treatment lies in treating high blood pressure and other underlying conditions of the disease.
Water pills help control sweating, thus increasing the fluid flushed from the kidneys.
Statins reduce cholesterol level.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
For kidney failure, dialysis can come to the aid in eliminating excess fluids and regulating hypertension.


Nephrotic Syndrome: Causes and Treatment

If you notice blood while urinating, you must visit a urologist to get a clear picture of the health issue. Blood in urine is known as hematuria in medical terms. Such a condition can occur in both men and women. It is a common condition and does not require the patient to panic. Rather immediate tests should be conducted to find out the cause of the blood and treated accordingly. Such conditions are very much treatable with a little care and vigilance following of the doctor s advice. Here are some of the common causes of hematuria in individuals: 

Urine Infections: Urine infections are the common cause of blood in your urine. Most commonly these affect urinary bladder and rarely kidneys also. Prompt identification and treatment can easily revert this problem. 
Urinary Stones: Another major cause of hematuria, usually accompanied by pain in the abdomen. 
Enlarged Prostate: With an enlarged prostate, there can be blood flow with the urine. Rarely this may be a sign of cancer in the prostate. 
Exercise: This might come as a surprise for many of the fitness freaks. While exercises are needed for the body and rightly so; but exercises should be done in a certain limit. Heavy exercises, limitless and vigorous exercises can sometimes cause other health problems in the body. One such problem is the passing of blood in the urine. 
Medications: Quite interesting is the fact that long-term consumption of certain medicines might cause hematuria in individuals. Certain medicines like penicillin and aspirin are absorbed by the body to a certain extent. But overdose or the regular dosage might lead to further problems in the human body. 
Kidney Injury: A kidney injury is a form of internal injury which can be felt and manifested through signs and symptoms. Such injuries occur mostly to those who are in the field of sports. At times, a heavy punch, a hard training session, or an exhaustive fall might lead to kidney injuries. This, in turn, would cause hematuria. 
Tumors of Urinary Tract: Bleeding can occur from tumors arising from kidney, ureter, urinary bladder as well as urethra. These require timely detection and management. Early treatment leads to an excellent long-term outcome. 
Thus, these are some of the common reasons for the development of blood in urine. However, it is a condition which can be best analyzed by the medical practitioner. Therefore, on the occasion of blood, you must get it tested and treated immediately.

Blood In Urine - What Does It Mean?

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