Cystic Fibrosis is a genetic disorder that is known to affect some of the vital organs of the body including the lungs, digestive system to name a few. For long it was believed that cystic fibrosis affects a person in their childhood. However, various research and studies suggest that adults are also susceptible to this inheritable disorder. In this article, we will discuss the cause and symptoms associated with cystic fibrosis.

Cause
The epithelial cells that line the stomach, nasal cavity and lungs, are responsible for the production of the digestive fluids, sweat, tears, mucus. The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene codes for a protein called the CFTR protein. The CFTR protein, a membrane protein plays a pivotal role in transporting the chloride ions of the epithelial cells inside and out of the cell. This regulation of the chloride ions goes a long way in ensuring that the mucus produced is free-flowing and thin.

In the case of Cystic Fibrosis, the CFTR gene that codes for the protein undergoes a mutation. With the CFTR protein unable to perform its function, sticky and thick mucus builds up and clogs some of the major systems of the body including the digestive system, reproductive, and respiratory system. There is also a higher salt content in the sweat of the affected person.

For a person to be affected by cystic fibrosis, he/she must inherit a copy of the mutated CFTR gene from both the parents ( Autosomal Recessive Disorder) at birth.

Symptoms
The symptoms associated with cystic fibrosis depends on the organs and systems affected.

The thick mucus formed can clog the digestive tract resulting in incomplete absorption of the essential nutrients from the food. This may have an impact on the overall growth and development of the body.
- There may be stunted growth or no weight gain.
- The stool may appear greasy and foul smelling. Some may also suffer from constipation.
- Newborns and infants may suffer from an intestinal blockage.
Cystic fibrosis, left unattended can lead to diabetes, intestinal blockage or obstruction.
- The mucus can also block the bile duct triggering a host of problems including liver disorders.
- At times, the obstruction or blockage can occur at the junction where the large and the small intestine meets (Distal intestinal obstruction syndrome).
The thick mucus can also affect the lungs and the respiratory system by blocking the tubes that act as a passage carrying the air inside and out of the lungs. As a result,
- A person may suffer from lung infections frequently.
- There may be difficulty in breathing, stuffy and blocked nose, or wheezing.
- Some people may also suffer from a chronic cough with a thick sputum.
Left untreated the complications can worsen resulting in

Nasal polyps, Chronic infections, Hemoptysis (there is blood while coughing), and Pneumothorax (air fills up in the space bifurcates the chest wall from the lungs).

In severe cases, there may be a respiratory failure.

Cystic fibrosis can also trigger fertility problems (both in males and females).

Cystic Fibrosis- Causes and Symptoms!

Parents sometimes tend to neglect their children due to various reasons. However, this negligence influences the children severely. It can affect the development, personality, relationship traits of the children. Every child needs care and love. Parents are naturally the closest people in a child s world. Negligence from the closest people can lead to destructive character traits in their personality.

1. Attachment problems: One of the primary and direct effects of parental negligence towards children can lead children to be less attached with family. If a child does not get the warmth and care from parents, he automatically detaches from the family bonding and even does not develop the love and compassionate feelings for the family. This pattern hardly changes over time, and it can even lead to problematic relationship of the child in the future. The child may not be able to be close to his own children later.

2. Brain development: Children are tender and sensitive, just like floral buds. Every stimulus has an action. For instance, a child who is affected by malnutrition suffers from weak neural cells. This can be a reason behind weak brain functions. The basic pillars of brain processes, that is, thinking and logical thinking, everything is affected due to parental negligence. It may lead to low level of self-confidence, depression, frustration, anxiety, troubled thoughts and emotional distortions.

Signs of parental negligence in children

1. Eating Disorders

2. Disrupted Sleep

3. Withdrawal from family bonding

4. Aggressive attitude

5. Bed wetting

6. Missing out school

7. Obsessive traits in behavioural patterns

8. Nightmares

9. Sudden change in attitude and behaviours

10. Depression

11. Violence

Every child seeks complete attention and love of his or her parents. However, parents may neglect them due to work stress, social obligations, personal problems and other such reasons. But parents should be considerate about the developmental barriers that could be posed due to this type of negligence. Some children also show eating habit changes, abusive attitude, violence or sometimes even plunge into complete isolation. While children require free scope to let their emotional and mental development boost with social activities, neglected children can withdraw themselves from social activities.

This means no friends, no social activity in life. This is a major reason for depression, suicidal attempts, deformed thought processes and misled lifestyle. As a parent, you can offer your optimum care and affection to your child to avoid such mental distortions, which can be avoided with love and warmth.

How Neglect from Parents Affects Your Child?

Coughing during the night can really wreak havoc for your sleep and cause inexplicable discomfort in the throat and chest region. Thankfully, you can manage it by soothing your tickling throat as well as sensitive airways before you go to bed at night. 

Drink herbal tea: A mugful of non-caffeinated tea mixed with a teaspoon of honey before going to bed can help you to a considerable extent. This is because any warm liquid has the power to break down the formation of mucus in the throat region and with a bit of honey, the herbal tea becomes even more powerful.
Try to sleep in an inclining position: Gravity is your greatest enemy while combating night-time cough. When you lie down flat on your back at night, all the mucus and dust particles, which you have swallowed all through the day, would accumulate in the throat area and aggravate it making more cough. But you can easily defy gravitational force by piling up some pillows and prop yourself on them while sleeping. You may also keep a wooden block of 4 inches height under your head, which would keep the acids in the stomach so that they don t come up to irritate your throat.
Make sure you use the steam cautiously: When your airways are dry, it can make you cough harder. Therefore, you may find relief if you take a warm shower or a bath before going to bed. But you have to be sure that you don t have asthma as steam can prove harmful for you.
Check the level of humidity: Humidifiers are known to soothe the problem of persistent coughing when the surrounding air is dry. But too much of moisture during the night can also make you cough. This is because dust mites, mold and other allergens thrive well in the damp air and they could conspire to make your cough even worse. So, pick up a cheap hygrometer from a hardware store and see that the humidity level stays within 40 to 50 percent.
Equip yourself at night: Keep all the things from drops to water to cough syrup or anything that soothes coughing at your bedside so that you can help yourself in case you wake up in the middle of the night and start coughing.
By following these few tips every day, you can manage the night time cough and have a good night s sleep without any interruptions.

Night Time Cough - 5 Tips to Manage it

Iron is an essential nutrient and mineral that is required by adults and children alike. Iron helps move oxygen from the lungs to the rest of the body and helps muscles store and use oxygen. It is especially important for children because it aids development and prevents anaemia. Untreated iron deficiency in children can cause physical and mental delays. It can lead to less healthy red blood cells in the child's blood stream which will cause a delay in the growth of physical and mental faculties.

Risk factors for iron deficiency in children

Infants and children at highest risk of iron deficiency include:

Babies who are born prematurely or have a low birth weight
Babies who drink cow's milk before age 1
Breast-fed babies who aren't given complementary foods containing iron after age 6 months
Babies who drink formula that isn't fortified with iron
Children ages 1 to 5 who drink more than 24 ounces (710 milliliters) of cow's milk, goat's milk or soy milk a day
Children who have certain health conditions, such as chronic infections or restricted diets
Children ages 1 to 5 who have been exposed to lead
Adolescent girls also are at higher risk of iron deficiency because their bodies lose iron during menstruation.
Symptoms of iron deficiency anaemia

The signs and symptoms of iron deficiency anaemia in children may include:

Pale skin
Fatigue or weakness
Slow cognitive and social development
Inflammation of the tongue
Difficulty maintaining body temperature
Increased likelihood of infections
Unusual cravings for non-nutritive substances, such as ice, dirt or pure starch
Prevent iron deficiency in children

Take steps to prevent iron deficiency in your child by paying attention to his or her diet. For example:

Breast-feed or use iron-fortified formula. Breast-feeding until your child is age 1 is recommended. If you don't breast-feed, use iron-fortified infant formula.
Encourage a balanced diet. When you begin serving your baby solids, typically between ages 4 months and 6 months, feed him or her foods with added iron, such as iron-fortified baby cereal. For older children, good sources of iron include red meat, chicken, fish, beans and dark green leafy vegetables. Between ages 1 and 5, don't allow your child to drink more than 24 ounces (710 milliliters) of milk a day.
Enhance absorption. Vitamin C helps promote the absorption of dietary iron. You can help your child absorb iron by offering foods rich in vitamin C, such as melon, strawberries, kiwi, broccoli, tomatoes and potatoes.
Consider iron supplements. If your baby was born prematurely or with a low birth weight or you're breast-feeding a baby older than 4 months and he or she isn't eating two or more servings a day of iron-rich foods, talk to your child's doctor about oral iron supplements.
Make sure that you watch out for the tell tale signs of iron deficiency and take the necessary precautions to avoid the same.

Iron Deficiency - How it Puts Your Child at Risk

Breastfeeding is best for the baby and its benefits extend well beyond the paradigm of basic nutrition. Breast milk contains all the vital vitamins and nutrients, which a baby needs in the first six months of life. It is fully loaded with disease fighting substances, which protect baby from illness. Many international paediatric organisation recommend exclusive breastfeeding for the first six months and recent research reports have proven that breastfeeding is good for both mother and the baby.

Breastfeeding protects the baby from a long list of illnesses, such as ear infections, lower respiratory illnesses, stomach disorder and meningitis and are less severe when they do happen. Breast milk adapts as the baby grows to meet the changing needs. Breastfeeding builds a strong emotional bond between the mother and the baby and it has long term benefits lasting right into adulthood.

The first milk of the mother contains high concentrations of secretory immunoglobulin A (IgA), which guards against invading germs by forming a protective layer on the mucous membranes in baby's intestines, nose, and throat. Mother's body responds to pathogens (virus and bacteria) that are in her body and makes secretory IgA, which is specific to those pathogens, creating protection for the baby based on to whatever mother is exposed. 

The antibodies in breast milk gives a baby's immune system a boost and also helps children avoid type 1 and type 2 diabetes, high cholesterol and inflammatory bowel disease that strike later in life. Babies who were not breastfed run the risk of developing Crohn's disease and ulcerative colitis.

Breastfeeding boosts child's intelligence. Surveys have shown that premature infants with extremely low birth weight who receive breast milk shortly after birth improved their scores of mental development at eighteen months when compared with premature infants who weren't given breast milk. The emotional bonding happening during breastfeeding contributes to some of the brainpower benefits. Breastfeeding lowers the risk of sudden infant death syndrome (SIDS). It reduces a child's risk of becoming obese as a teen or adult as the breast milk contains less insulin, which stimulates creation of fat. The high content of leptin in the milk regulates appetite and fat.

Breastfeeding triggers the release of the hormone oxytocin that promotes relaxation and nurturing. Oxytocin released while nursing also helps your uterus contract after birth, resulting in less postpartum bleeding. It reduces stress level and the risk of postpartum depression. Research studies show that breastfeeding results in changes in breast tissue and lactation reduces the production of oestrogen, which reduces the risk of breast and ovarian cancer. It also reduces the risk of osteoporosis and cardiovascular disease.

Benefits of Breastfeeding for Baby & Mother

You look your best when you wear a smile on your face. Everyone prefers a smiling face over a frowned one. Since we are talking about smiles, one can never underestimate the role that teeth play in the beauty of a smile. Dental hygiene and care is mandatory if you wish to secure your beautiful smile for years to come.

However, the global statistics for dental care suggests that we do not care enough for our teeth. 60-90% of children who are in school and almost every adult suffer from dental cavities. Dental cavities are pretty common nowadays. And yellowing of teeth can now be seen in almost every other person. It spoils the smile and makes people conscious. By ensuring a few dental care habits in your daily routine lives, you can avoid yellow teeth. Let us discuss the tips and tricks to avoid yellowing of teeth.
 
1. Say no to specific foods: Yellowing of teeth is caused by food choices including coffee, red wine, sodas, juices, sports drinks, white wine, coloured candies and other artificially coloured foods. It will help if these foods are consumed in less quantity and frequency as they are the major contributors towards discoloration of teeth.

2. Water after every coloured drink: Here is a habit that you must inculcate in your routine, whenever you consume any of the above mentioned food items. Post every drink or food intake which can cause tooth-staining, top it up with a glass of water. When you swirl or gargle the water in your mouth, you remove the acids that get accumulated in your mouth. It is one of the simplest preventive measures one can implement to avoid tooth stains.
 
3. Dental Hygiene: Our parents and dentists kept reminding us all the time to brush twice a day and gargle with water post every food intake but did we listen to them as kids? No we did not. Proper brushing, flossing and going for dental checkups at regular intervals are sure shot ways to keep your teeth healthy for majority of your lifetime. One must develop these habits quite early in life to gain benefits from it.

4. Whiten those Yellow teeth:  You might be at that stage of your life where inculcating the above mentioned habits won't do much good. The damage might already have been done. Your teeth are probably yellowish already and you have a history of dental cavities. In this 21st century, there are ways to whiten your teeth artificially with the many alternatives available in the market. One can opt for a solution, which can be done at home itself or go for a laser whitening which is now possible at a dentist clinic.
 
So there is still hope for those who are unable to share that smile with the world due to the yellowing of teeth. Nothing is irreparable here and the health of your teeth lies in your hand.

How to Avoid Yellowing of Teeth

Don't wait any longer, manage your Neonatologist online with a Lybrate doctor today

Consult for Neonatologist - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES