People with sickle cell disease often experience myriad symptoms of the disease that can be controlled by the right nutrition. Reports suggest that nutrition is an increasingly significant factor to prevent symptoms such as slow growth, lower body mass, joint issues, infections, pain crises, and anemia.

There is a greater than the typical requirement for both calories and micronutrients.

The nutritional requirement of a sickle cell patient emphasizes more on vegetables, fruits, whole grains, and more similar food items. These can prevent any deficiencies in the body and also decrease any chances of disease exacerbation.

 


	
	High-calorie nutrient-dense diet
	


The usual energy intake in a sickle cell patient is normally lower than the average values. It is a case even when the condition is asymptomatic where the requirement drops to half the level. As a result, people with sickle cell diseases (especially kids) are at higher risk for impaired growth and considerably lesser fat and fat-free mass, with obesity also posing a risk. It is suggested to have adequate energy supplements in the diet to reach the minimum sufficient requirement of the body that can be done only by proper nutritional assessment.


	
	Adequate fluids
	


Avoiding dehydration is another significant factor to avoid any severe symptoms of sickle cell disease. Sickling of the erythrocytes aggravates in patients who perform hardcore physical work in the heat without drinking enough fluids. This leads to dehydration and can even result in constipation.


	
	Micronutrients
	


Micronutrient deficiencies can be found in sickle cell patients up to a great extent. Several vitamins and minerals like vitamin a, b6, c, e, carotenoids, zinc, and magnesium are often found in fewer numbers in scd patients. A significant drop in blood-antioxidant status may result in acute chest syndrome. The supplementation of these vitamins and minerals can reduce the number of sickled cells in the body. Plant phenols and flavonoids may also help in lowering oxidative stress.


	
	Calcium-rich food
	


Getting plenty of calcium-rich food like dairy products, leafy vegetables, cereals, and fruit juices aids the child's growth and development. This may lead to a stronger physical structure and a greater resistance to the disease.


	
	Omega-3 fatty acid
	


There are reduced proportions of omega-3 polyunsaturated fatty acids in sickle cell patients. These acids aid the fluidity of red blood cell membranes. As a result, they prevent sickle cell crises. Supplemental docosahexaenoic (dha) and eicosapentaenoic (epa) have shown numerous therapeutic benefits in scd patients.


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Role Of Nutrition In Sickle Cell Disease

Hepatitis- related to an inflammatory condition of the liver. It occurs mainly due to infection caused by viruses but there are other possible causes as well. Hepatitis can be temporary or viral. Temporary hepatitis, which is acute in nature, gets resolved on its own. Viral hepatitis can be of five types, a, b, c, d, and e.

Symptoms of hepatitis

Hepatitis, in its initial phase, is called the acute phase. The following symptoms along with mild flu are visible:

Loss of appetite
Fatigue
Joint pains
Pain in the abdomen
Nausea
Weight loss
Jaundice
Though this phase is not really dangerous for some patients, it can result in liver failure leading to death.

How is hepatitis diagnosed?

Physical examination
Laboratory tests
Imaging tests


Treatment for hepatitis

Treatment options for different types of hepatitis are:

Hepatitis a: this doesn t require treatment as it is short-term in nature. In case the symptoms cause a lot of discomforts, then bed rest is recommended. The vaccine is available to prevent this infection.

Hepatitis b: acute hepatitis b doesn t require treatment either. Its chronic form can be treated with antiviral medications. This can be prevented with vaccination.

Hepatitis c: this type of hepatitis, both in its acute and chronic forms, is treated through antiviral medications.

Hepatitis d: according to a study in 2013, a drug known as alpha interferon is used to treat this type of hepatitis. Unfortunately, this only comes to the rescue of 25-30% of people.

Hepatitis e: this acute form of hepatitis gets resolved on its own. Adequate rest, drinking a sufficient amount of water, and taking enough nutrients in their food are some of the ways to get healed from this disease.


 

Hepatitis: Signs, Diagnosis, And Treatment

People suffering from sickle cell disease (scd) usually start showing symptoms very early. They can appear to show up even during the first year of life. Symptoms of a sickle cell vary from one person to another and can be mild to serious depending on the condition.

 

Sickle cell disease is a health condition that worsens with time. Despite the absence of any full-proof solution, some treatments prevent further complications. These treatments can help patients receive aid for a lifetime. Simply said, sickle cell diseases can be managed medically.

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Treatment

Treatment in a sickle cell patient depends on the severity of the symptoms. Preventing complications and relieving pain is the primary aim of the diagnosis. They can range from medications to blood transfusions.

 

Concerns

Some of the concerns that need to be taken care of during the treatment of scd are-

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	Prevent painful scenarios
	


A painful episode or sickle cell crisis can be avoided by consuming sufficient fluids, wearing warm clothing, and staying away from sudden temperature changes.

 


	
	Avoid infections
	


Children with sickle cell anemia are made safe from infections by using penicillin. Adults with anemia might need to take penicillin all their lives. Doctors should ensure that all vaccinations in children and adults are periodically done to avoid any infections. However, during the covid-19 pandemic sickle cell patients should take extra care.

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Medications

While there can be numerous ways to manage sickle cell treatment, medications help in a significant way. Some of the prescribed medicines are-


	
	Hydroxyurea- it reduces the frequency of sickle crises. Pregnant women should stay away from this according to experts.
	
	
	Crizanlizumab- this drug injected into the patient can help reduce the sickle crises in adults and children over the age of 16.
	
	
	Voxelotor- it is an oral drug used in children over 12. It lowers the risk of anemia by improving blood flow.
	
	
	Pain-relievers- narcotics to prevent excessive pain can also be used during the treatment.
	


 

Surgical procedures


	
	Blood transfusion
	


It is used to prevent stroke and other related complications in patients. This can increase the number of red blood cells in the body that can help reduce the symptoms.

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	Stem cell transplant
	


It is also called a bone marrow transplant and is used to replace affected bone marrow with a healthy one. This procedure is carried out between matched donor and recipient. Although it is a known cure for sickle cell disease, various risks involved make it a less used practice.

 

Can Sickle Cell Be Cured?

Air pollution affects the overall health of a human being. Whether it comes out of exhaust fumes from cars and factories or smoke from burning stubble air pollution, it is a cause of major concern. The effects of this can be seen in the growing number of asthma and other respiratory diseases. These diseases affect adults and children alike, however, it is the younger generation and elderly people who are more susceptible. Hence, it is extremely important to care about the quality of the air you breathe in. 


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What is the significance of the air quality index (aqi)?

The air quality index is a visual representation of pollutant levels in the air around you. A quick glance at this colour coded map can tell you if the air outside your home is likely to harm you or not. The code is broken down into 6 levels ranging from green which signifies minimal impact to red which marks pollution levels that can harm a healthy person and seriously impact those who are already ill. The higher the aqi, the higher the level of air pollution.

 

What are the steps to reduce air pollution?

Simply talking about how there need to be stricter laws about car emissions and the burning of waste will not help you. Here are a few things you can do to protect yourself and your family from the ill-effects of air pollution.


	
	Carpool: exhausts from cars and other vehicles are one of the biggest causes of air pollution. Do your part to reduce air pollution by restricting the amount you use your car. Try taking public transport to work or carpooling with colleagues. Similarly, avoid making individual trips every time you need something from the market. Make a list and when it s long enough, then step out.
	
	
	Limit indoor pollution: do not smoke indoors. When cooking, keep the exhaust fan on so that the smoke produced does not collect indoors. Avoid spraying air fresheners etc. While they may temporarily make the air smell fresh, in the long run, they contribute to air pollution.
	
	
	Use public transport try to use public transport and avoid the use of personal vehicles.
	


How to protect yourself from air pollution


	
	Refrain from morning walks routines to later hours.
	
	
	Use n95/99 face masks whenever you step out.
	
	
	Use air-purifying plants to purify the air around your surroundings.
	
	
	Ventilate your kitchen, and bathroom to keep yourself away from air pollution.
	
	
	Restrict outdoor activities for kids if there is a high level of air pollution
	
	
	Use air-purifiers in your surroundings.
	
	
	Try to take steam with a few drops of eucalyptus oil every day.
	
	
	Keep your car s environment fresh.
	
	
	Ventilate your home, open your windows and doors and allow the air to circulate during mid hours.
	
	
	Eat jaggery (aka gurr) to flush out pollutants from your lungs.
	
	
	Consume a diet rich in vitamin c, omega fatty acids
	


Hence, the other way to cut down this pollution is by bringing significant lifestyle changes in our daily living. Cutting down the number of diesel and petrol vehicles can also prove helpful. People should shift to cng and electric vehicles for daily commuting. These efforts, if practiced on a regular basis, can bring a huge decrease in pollution.

Air purifiers can also be a healthy option for indoor purposes.

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Why Should You Care About Air Quality?

What are the different types of sickle cell disease?

Sickle cell disease or sickle cell disorder is a term often used to talk about a group of diseases affecting hemoglobin. It is the oxygen-carrying element of blood that makes up 2 alpha globins and 2 beta globins. Sickle cell disease happens due to beta-globin mutation and depending on the abnormality in mutation.

Types-
Sickle cell diseases can be of many types depending on the gene mutation in the blood. Some of the common types are-

Sickle hemoglobin s disease (ss)
Hemoglobin ss disease or sickle cell anemia is the most popular type of scd. It takes place when hemoglobin s gene mutation is inherited from both mother and father. In simple words, it happens when the child inherits one substitution beta-globin gene from each parent. In this type, the body only produces hemoglobin s. It is mostly found in people of african and indian origin.

Sickle hemoglobin- c disease (sc):
Patients with sickle hemoglobin sc disease have a moderately dissimilar swapping in their genes of beta-globin. Here, both hemoglobin c and hemoglobin s are inherited from each parent. It may cause similar symptoms like anemia but remains relatively l. People of west african and mediterranean origin are more prone to this.

Hbs beta-thalassemia
People with this type of scd inherit one sickle cell gene s and one gene for beta-thalassemia from each parent. Zero and plus are the two common types of beta-thalassemia. While beta 0 thalassemia usually takes a severe form, beta + thalassemia is a milder form of the disease.

Sickle beta-zero thalassemia
Beta-zero thalassemia takes form when the child inherits the beta s gene from one parent and beta 0 thalassemia gene mutation from the other. With similar symptoms to anemia, it is a slightly severe form of beta-thalassemia.

Sickle beta-plus thalassemia
Substitutions in both beta-globin genes take place in patients with sickle beta thalassemia (sb) disease. This may even lead to the requirement of blood transfusion if no normal beta globin is produced. Mediterranean and caribbean people are more likely to have this disorder.

Hemoglobin sd, hemoglobin se, and hemoglobin so
These are the few rare and not less common types of sickle cell diseases. They are also less severe. People with these forms of scd inherit one sickle cell gene s and one gene from uncommon hemoglobin (d, e, or o) from each parent.

Sickle cell trait
Hbas
People with sct have one sickle cell gene s and one normal gene a from both mother and father. Ones with this disorder show few to no signs of the disease and usually spend a normal life. However, the risk to their future generations still exists.
 

What Are The Different Types Of Sickle Cell Disease?

Kidney - prolonged periods of stress can indirectly hurt your kidneys. So you need to be stress free to keep your kidneys healthy.

Stress And Kidney Failure: Are They Connected?

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